Beck Depression Inventory-II Questionnaire Research Articles

Association Between Physical Activity and Depression in Middle Aged Premenopausal and Postmenopausal Women in Malaysia

Objective: The objective of this study was to investigate the relationship between physical activity levels and depression among middle-aged premenopausal women in Malaysia. Methods: A cross-sectional study was conducted in a community centre, workplace, and healthcare institution. The Beck Depression Inventory-II questionnaire was used to assess the severity of depression symptoms. Multiple logistic regression analysis was conducted to determine the association between the amount of physical activity and depression. Results: Compared to those with low activity levels, participants with moderate activity levels had 25% lower odds of experiencing depression (adjusted OR = 0.75, 95% CI [0.60, 0.92], p 0.05). Participants with high activity levels also had 35% lower odds. Conclusions: This study highlights the significant inverse relationship between the level of physical exercise and depression in Malaysian women. Encouraging regular physical activity as a part of lifestyle interventions may serve as an effective strategy for preventing and managing depressive symptoms in this population. Further research is needed to explore the underlying mechanisms and to inform targeted interventions for promoting physical activity, thus promoting positive mental health outcomes.

Depresi sebagai Prediksi Kematian dalam 1 Tahun pada Pasien Hemodialisis

Depression is a mental disorder that is often found in hemodialysis patients. Depression had bad effects on patients. The study that determines the relationship between depression and all-cause mortality risk in hemodialysis patients is debatable. Objectives: To determine the role of depression as a predictor factor of all-cause mortality within one year in hemodialysis patients. Methods: This cohort study was conducted from February to August 2020 at the hemodialysis unit of Roemani Muhammadiyah Hospital, Semarang. The inclusion criteria were undergoing hemodialysis ≥3 months, hemodialysis frequency twice a week, being willing to participate in this study, being able to communicate well, and there was no history of previous mental disorders. Meanwhile, those whose data were incomplete, transferred to another hemodialysis unit, HBSAg +, and had other stressors unrelated to hemodialysis or Chronic Kidney Disease (CKD) were excluded from this study. Depression was assessed using the Beck Depression Inventory-II questionnaire. The collected data was then analyzed using Kaplan Meier and Cox regression. Results: From 82 respondents, 20 (24,4%) respondents categorized into depression group and 62 (75,6%) respondents into non depression group. Cox Regression analysis showed that depression plays a role as a predictor factor of all-cause mortality within one year in hemodialysis patients (p value=0,007, and Hazard ratio=3,587). Conclusion: Depression plays a role as a predictor factor of all causes of mortality within one year in hemodialysis patients.Keywords: depression, hemodialysis, mortality, end-stage renal disease

Hubungan antara penggunaan obat antiretroviral berbasis evafirenz dengan prevalensi gangguan depresi pada penderita HIV di klinik penyakit tropik dan infeksi terpadu RSUP Sanglah

Background: Efavirenz as the first-line ARV most frequently used worldwide has a neuropsychiatric side effect that is still debated. Early identification of depressive symptoms determines adherence to treatment. Objective: To determine the prevalence of depressive disorders in a population of HIV patients using efavirenz-based ARVs. Methods: This study used a cross-sectional observational research design with a consecutive sampling method that was conducted at the Sanglah Hospital's Integrated Tropical Disease and Infectious Disease Clinic during May to June 2019. Measurement of depression used the Beck Depression Inventory-II questionnaire. Data analysis used SPSS version 21 with chi square test. Result: The sample size was 90 people, the majority were men (58.9%) with a mean age of 36 ± 7.23 years and a long period of suffering from HIV 5 ± 3.82 years. The population of respondents who received efavirenz-based ARVs was 65.6% with a depression prevalence of 37.3%. The results of the chi-square test analysis showed that there was no significant relationship between the use of Efavirenz-based ARVs and the prevalence of depressive disorders (p = 0.86). Conclusion: More than a third of the sample population had a depressive disorder and was not associated with the use of EFV-based ARVs.

Mood Reactive Disorders among COVID-19 Inpatients: Experience from a Monocentric Cohort

Objective: We aimed to investigate the presence and severity of depressive symptoms among coronavirus disease 2019 (COVID-19) inpatients and any possible changes after their discharge. Subject and Methods: We collected data of patients admitted to the Infectious Disease Unit in Sassari, Italy, for COVID-19, from March 8 to May 8, 2020. The Beck Depression Inventory-II (BDI-II) was performed 1 week after admission (T0) and 1 week after discharge (T1). The cutoff point chosen to define the clinical significance of depressive symptoms was 20 (at least moderate). Results: Forty-eight subjects were included. Mean age was 64.3 ± 17.6 years, and 32 (66.7%) were male. Most frequent comorbidities were cardiovascular diseases (19; 39.6%) and hypertension (17; 35.4%). When performing BDI-II at T0, 21 (43.7%) patients reported depressive symptoms at T0, according to the chosen cutoff point (BDI-II = 20). Eight (16.7%) patients had minimal symptoms. Mild mood disturbance and moderate and severe depressive symptoms were found in 24 (50%), 14 (29.2%), and 2 (4.2%) patients, respectively, at T0. The comparison of the BDI-II questionnaire at T0 with T1 showed a significant improvement in the total score (p < 0.0001), as well as in 4 out of the 5 selected questions of interest (p < 0.05). Univariate analysis showed that kidney failure and the death of a roommate were significantly associated with severity of mood disorders. Conclusion: Mood disturbances and depressive symptoms commonly occur among COVID-19 inpatients. Our results show that COVID-19 inpatients might be at higher risk for developing depressive reactive disorders and could benefit from an early psychological evaluation and strategies improving sleep quality.

Interleukin 6, interleukin 17, disease-related and contextual factor association with depression, and its severity in patients with rheumatoid arthritis.

Depression is very prevalent in rheumatoid arthritis (RA) compared with the general population and may be associated with poor clinical outcomes. Identifying factors associated with depression could improve outcomes for this at risk group. However, few studies have comprehensively examined the association of contextual and disease-related factors as well as pro inflammatory cytokines interleukin 6 (IL-6) and interleukin 17 (IL-17) with depression in RA. Therefore, we aimed to identify the factors significantly associated with depression and severe depression in RA, thus providing a reference for applying clinical care interventions for patients with RA. An observational cross-sectional study was conducted on 120 RA patients. Potential determinants included contextual and disease-related factors and laboratory variables. Enzyme-linked immunosorbent assay was used to measure serum IL-6 and IL-17 levels. Depression was assessed using the Arabic version of the Beck Depression Inventory-II questionnaire. A total of 120 patients were included, and up to 67.5% had some degree of depression with 60% having moderate to severe depression. The severity of disease activity of RA (DAS28-ESR (OR, 1.63; 95% CI, 0.899-3.755), HAQ scores (OR, 1.27; 95% CI, 0.702-2.933), and VAS scores for pain (OR, 2.2; 95% CI, 1.251-5.223)), besides elevated serum IL-6 (OR, 1.51; 95% CI, 0.832-3.475), IL-17 (OR, 1.28; 95% CI, 0.706-2.947), and CRP levels (OR, 1.20; 95% CI, 0.923-2.882) were significantly associated with depression and its severity in the multivariate analysis. Depression is frequent in RA and is strongly associated to elevated serum IL-6, IL-17, CRP levels, and disease activity-related factors. Key Points • RA patients are at increased risk of developing depression, particularly if their level of disease activity scores, serum IL-6, and IL-17 levels increases. • Patient characteristics associated with depression in RA include living without family, without employments, and with co-morbid hypertension, while RA disease factors are pain, functional disability, and high disease activity. • A multidisciplinary cooperative approach to RA patient care with regular assessments of these factors associated with depression should be incorporated into routine care programs to improve patients' self care capabilities and mitigate or prevent depression in these patients.

The Relationship between Household Food Insecurity and Depressive Symptoms among Pregnant Women: A Cross Sectional Study

Objective: There is growing evidence suggesting that household food insecurity (HFI) is associated with adverse outcomes on mental health; however, limited evidence exists for pregnant women. This study was conducted to determine the relationship between HFI and depressive symptoms among a sample of pregnant women. Method : This cross sectional study was performed on 394 pregnant women referring to the health centers located in Qom, Iran, from October 2017 to March 2019. HFI was evaluated using an 18-item US Household Food Security Survey Module. The Beck Depression Inventory-II questionnaire was applied to determine the severity of depressive symptoms. Logistic regression analysis was used to determine the factors associated with elevated depressive symptoms in the study population. Results: The mean (± standard deviation) age of the study population was 28.59 ± 7.28 years. Almost 48% of participants were food insecure, and 37% experienced elevated levels of depressive symptoms during pregnancy. The prevalence of elevated depressive symptoms was significantly higher in food-insecure (P < 0.001) and unemployed (P = 0.02) women, while it was significantly lower in women with higher education levels (P < 0.001). In the adjusted model, it was revealed that HFI was significantly associated with the higher likelihood of having elevated depressive symptoms (OR = 3.31, 95% CI = 2.07, 5.29), while the higher level of education was negatively associated with the levels of depressive symptoms (OR = 0.40, 95% CI = 0.20, 0.79). Conclusion: HFI was positively associated with the severity of depressive symptoms in a sample of pregnant women. Further studies are needed to confirm this finding. Meanwhile, routine screening of HFI for all pregnant women in the community health centers is recommended.

The Depression Level of Women Suffering Domestic Violence in Medan, Indonesia

BACKGROUND: Domestic violence is defined as a social problem associated with an increased risk of mental illness in women. The violence experienced by women can be a traumatic event that leads to a psychological disorder. Domestic violence has a strong relationship with depression, including depressive symptoms, depression disorders, and suicide. Risk factors associated with depression in women victims of domestic violence are including age, education level, socioeconomic status, and long experience of violence.&#x0D; AIM: The aim of this study was to find the risk factors associated with the level of depression in women who experience domestic violence.&#x0D; METHODS: This was a cross-sectional study and conducted at the Psychiatric Clinic of Dr. Pirngadi General Hospital, Medan. Subjects were 82 people of victims of domestic violence and recruited using non-probability sampling which was consecutive sampling. Subjects that meet the inclusion criteria were interviewed with the ICD-10 (A1) version of the Mini International Neuropsychiatric Interview. Furthermore, subjects were asked to fill out the Beck Depression Inventory-II questionnaire. Finally, statistical analysis was performed using Chi-square and multivariate logistic regression through SPSS software.&#x0D; RESULTS: The most dominant risk factors for the level of depression were categorized with long experience of violence (odds ratio [OR] = 4.939, p = 0.018), economic level (OR = 4.436, p = 0.01), and education level (OR = 3.754, p = 0.022).&#x0D; CONCLUSION: A significant relationship is found between violence duration, economic level, and education level with the level of depression for women victims in domestic violence.

Correlation between perimenopausal syndromes and depression in nurses at Sanglah General Hospital

Background: Perimenopause covers the period immediately before the menopause and the first year after the last menstrual period. In addition to the changes in the menstrual cycle, women in the perimenopause phase often report a number of perimenopausal complaints and depressive disorders. This study aims to determine the prevalence of perimenopausal complaints and depression experienced in nurses at Sanglah General Hospital. Methods: The study uses a cross-sectional analytical. The measurement of perimenopause complaints uses the Menopause Rating Scale (MRS) questionnaire and the depression measurement uses the Beck Depression Inventory-II questionnaire (BDI-II). The data are analyzed descriptively, it uses the Fisher test and linear regression test with significance level p &lt;0.05. Results: Nurses who have perimenopausal complaints are 62.7%. Besides, depression is experienced by 23.8% of nurses who have perimenopausal complaints. The complained somatic symptoms with a mild degree are 50% and moderate degree is 40%. While the urogenital sexual symptoms with a moderate degree are 60%, and mild and severe degrees are 20%. Conclusion: This study shows the relationship between perimenopausal complaints and the depression of the nurses in Sanglah General Hospital. Therefore, it is necessary to hold an early detection of depression prevention by screening perimenopausal complaints.

Mild anxiety and depression related to elevated dopamine level

BackgroundDopamine is an important neurotransmitter that plays a role in the pathogenesis of anxiety and depression. Dopamine secretion occurs when there is a pleasurable stimulus. Blood dopamine levels have the potential to be developed as biomarkers of depression or anxiety, but previous studies related to the relationship between dopamine levels and levels of anxiety and depression are still controversial. The purpose of this study was to determine the correlation between anxiety and depression score with dopamine level in young adults. MethodsThis was an observational cross sectional study. A total of 43 subjects aged 18 to 40 years were recruited by consecutive non-random sampling according to inclusion and exclusion criteria. Anxiety and depression were assessed using the Beck anxiety inventory and Beck depression inventory-II questionnaire. Dopamine plasma level was measured using the enzyme-linked immunosorbent assay (ELISA). The Spearman rho correlation test was used to analyze the data and p&lt;0.05 was considered significant.Results The median dopamine levels in respondents with mild, moderate and severe anxiety were respectively: 77.79; 63.43; 62.51 ng/mL (p=0.043). The median dopamine levels in respondents with reasonable depression, mood disorder, moderate and severe depression were respectively: 79.2; 61,32; 62,51; 60.24 (p=0.001). Correlation test results showed a weak correlation between dopamine and anxiety (r=- 0.310) and a moderate correlation for depression (r=-0.505).ConclusionMild anxiety and depression were associated with elevated dopamine level in young adults. Further studies are required to confirm the role of dopamine metabolism in anxiety and depression in young adults.

Gender differences in platelet brain derived neurotrophic factor in patients with cardiovascular disease and depression

Women have a higher prevalence of depression compared to men. Serum levels of Brain-derived neurotrophic factor (BDNF) are decreased in depression. BDNF may also have a protective role in the pathogenesis of coronary artery disease (CAD) or events. We examined whether there are gender differences in BDNF levels in patients with stable CAD and comorbid depression. We enrolled 37 patients (17 women) with stable CAD with and without depression from a single medical center. All patients had depression assessment with the Beck Depression Inventory-II questionnaire. Both plasma and platelet BDNF were measured in all patients using a standard ELISA method. Platelet BDNF levels were higher than plasma BDNF levels in the entire group (5903.9 ± 1915.6 vs 848.5 ± 460.5 pg/ml, p < 0.001). Women had higher platelet BDNF levels than men (6954.2 ± 1685.6 vs. 5011.2 ± 1653.5 pg/ml, p < 0.001). Women without depression (BDI-II < 5, n = 8) had higher platelet BDNF than men without depression (n = 8, 7382.8 ± 1633.1 vs 4811.7 ± 1642.3 pg/ml, p = 0.007). Women with no or minimal depression (BDI < 14, n = 14) had higher platelet BDNF levels than men with no or minimal depression (n = 18, 6900.2 ± 1486.6 vs 4972.9 ± 1568.9 pg/ml, p = 0.001). The plasma BDNF levels were similar between men and women in all categories of depression. In conclusion, women with stable CAD have increased platelet BDNF levels when compared to men with stable CAD regardless of their level of depression. Sex specific differences in BDNF could possibly indicate differences in factors linking platelet activation and depression in men and women.

Evaluation of depressive symptoms in obese patients with or without acanthosis nigricans.

Acanthosis nigricans (AN) has been closely associated with obesity. Depression has also been shown to be disproportionally prevalent among obese people. However, there is still a paucity of studies on the relationship between depressive symptoms and AN in obese patients. This study examined the difference in metabolic disorders and depressive symptoms between simple obesity and obesity-related AN. A total of 88 obese patients treated in our department were selected for analysis. They were divided into simple obesity (OB n=30) and obesity with acanthosis nigricans (AN n=58). A control (CON) group included 56 normal weight healthy volunteers. The self-administrated Beck Depression Inventory-II questionnaire was used. General characteristics and clinical data were collected for analysis. The frequency of depressive symptoms was recorded as 67.2% in the AN group, 43.4% in the OB group, and 3.6% in the CON group (P <0.001). The severity of depression in the AN group was significantly higher than in the OB group and CON group (P <0.001). Patients with moderate depressive symptoms had higher levels of inflammatory markers than those with mild symptoms depression. Free fatty acid (FFA) and uric acid (UA) level in the AN group were significantly increased compared with the OB group (P=0.010, P=0.020). Discrimination was associated with depressive symptoms (P <0.001). Obese patients had a higher risk of depressive symptoms, which were even higher in patients with AN. AN is associated with more depressive symptoms and high inflammation status. Psychological intervention should be started early to prevent further physical and pathological impairment in obese patients, especially obese patients with AN.

Depression, abuse and its relationship to interstitial cystitis

This study evaluated the prevalence of depression, sexual abuse, and physical abuse among women diagnosed with interstitial cystitis (IC). One hundred forty-one subjects completed the validated Beck's Depression Inventory II Questionnaire (BDI-II) and the validated Drossman Abuse Questionnaire. Ninety-seven (69%) subjects scored 14 or higher on the BDI-II, corresponding to depression. When compared to the US prevalence of 9%, this was significantly higher. Fifty-one subjects (36%) reported sexual abuse which is higher than the US average. The prevalence of childhood sexual abuse in the sample was not significantly different than the US average. The prevalence of physical abuse in the sample was not statistically different than the US average. Women with IC appear to have a higher prevalence of depression and sexual abuse than the general population. Women with IC should be screened for depression and abuse and referred to a mental health expert as necessary for treatment.