This systematic review aims to identify the countriesmost active in combatting predatory journals and their definitions of such practices. It also seeks to assess awareness within academic communities, examine the impact of predatory journals on research quality and integrity, and compile existing policies to mitigate their negative effects and strengthen global scholarly integrity. A systematic search was performed in the PubMed, Scopus, and Embase databases on February 7, 2024, in line with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The focus was solely on identifying studies that examined the unique experiences and interventions associated with predatory journals in distinct national contexts. The analysis included a presentation of quantitative results and a thematic examination of qualitative data. A total of 40 articles covering 19 countries were included. Twenty-four countries (60%) were in Asia, 11 (27.5%) in Africa, two (5%) in Europe, and one (2.5%) each in Australia, North America, and South America. Although not all articles cited Beall's list to identify predatory journals, the thematic analysis showed consistent topics across various definitions and Beall's themes. Our analysis identified factors affecting academic publishing perceptions globally, highlighting publication pressure, predatory practices, and policy impacts on ethics and standards. This systematic review examined the literature on predatory publishing and identified the leading countries in the fight against these predatory publications. This analysis underscores a complex interplay of factors affecting academic publishing globally, from the push towards predatory journals as a response to publishing pressures, to the critical role of government and institutional frameworks.