This work addresses the nonfragile <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$H_{\infty }$ </tex-math></inline-formula> controller design problem for a class of discrete-time uncertain nonlinear systems. The norm-bounded uncertainty is contained in the nonlinear plant, which is described by the well-known Takagi–Sugeno (T–S) fuzzy model. The controller gain perturbation is also considered. When the input signal is transmitted from the controller to the system through the digital communication channels, it will be quantized by a static quantizer. The main attention is to design the nonfragile <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$H_{\infty }$ </tex-math></inline-formula> state-feedback controller for the closed-loop quantized uncertain T–S fuzzy system. By introducing some auxiliary scalars and the fuzzy basis-dependent Lyapunov function approach, sufficient conditions are established in the form of linear matrix inequalities (LMIs). The construction for the nonfragile <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$H_{\infty }$ </tex-math></inline-formula> controller can be completed by solving these LMIs. In the end, the applicability and effectiveness of the proposed method have been illustrated by two simulation examples.