Basic Chemistry Research Articles

GLOSSÁRIO AUDIODESCRITIVO: RECURSO DIDÁTICO INCLUSIVO NO ENSINO DE QUÍMICA

School inclusion is based on the idea that all students must attend the regular education network, with the school being responsible for adapting to receive the student, through the use of teaching methodologies, accessible teaching resources, always taking into account consideration of students' needs. This work aims to establish reflections on the inclusive potential of a multiformat glossary accessible in audio and audio description as a didactic resource, working on concepts related to atomic models and concepts of general chemistry. With regard to the research methodology, it was divided into four stages, namely: the choice of platform; study on audio description; study and choice of terms to compose the glossary; and the validation of the didactic resource, which was carried out in two stages, the first a priori and the second stage a posteriori. Some of the results that were obtained with the a priori validation process of the resource with the basic education chemistry teachers and with the advisor show the need to expand the contents to be included in the resource, in relation to the a posteriori validation, carried out by the blind people and people with low vision, it can be said that they believe that the resource is valid in the sense of making chemistry more accessible, less abstract, making it possible to actually learn this discipline. In conclusion, the research carried out has significant relevance, given that it allows students to have a space for speech and more autonomy in learning.

Transforming science literacy: assessing the ability of chemistry teacher candidates through the viewpoint of Islamic values

Science literacy assessment is important to familiarize students with literacy questions based on aspects of science knowledge and its interaction with the environment, technology, and society. Students' low science literacy is often caused by teachers' low science literacy. This study aims to analyze (1) the science literacy skills of chemistry education students in basic chemistry courses; and (2) the science literacy skills of chemistry education students based on competency aspects which are divided into three achievement indicators. This research is a descriptive study with a quantitative approach, with subjects 21 semester 6 students of the chemistry education study program at UIN Sayyid Ali Rahmatullah Tulungagung. The instrument used was a scientific literacy test in the form of an essay test with 22 questions which have been validated by 2 chemistry education lecturers, and the test results with a test reliability of 0.629, as well as a difficulty level of 1 easy question, 19 medium, and 2 difficult. The results showed that (1) students' science literacy skills were in the "sufficient" category with an average score of 43.9. (2) Analysis based on competency aspects shows the ability to explain phenomena scientifically and identify scientific issues is in the sufficient category, but the use of scientific evidence is low. The findings are expected to provide input to improve learning and practice of science literacy in preparing students as future educators.

“Basic Solid State Chemistry Second Edition” by Anthony R. West

“Basic Solid State Chemistry Second Edition” by Anthony R. West

Carbon Dots: A Versatile Platform for Cu2+ Detection, Anti-Counterfeiting, and Bioimaging.

Carbon dots (CDs) have garnered extensive interest in basic physical chemistry as well as in biomedical applications due to their low cost, good biocompatibility, and great aqueous solubility. However, the synthesis of multi-functional carbon dots has always been a challenge for researchers. Here, we synthesized novel CDs with a high quantum yield of 28.2% through the straightforward hydrothermal method using Diaminomaleonitrile and Boc-D-2, 3-diaminopropionic acid. The size, chemical functional group, and photophysical properties of the CDs were characterized by TEM, FTIR, XPS, UV, and fluorescence. It was demonstrated in this study that the prepared CDs have a high quantum yield, excellent photostability, and low cytotoxicity. Regarding the highly water-soluble property of CDs, they were proven to possess selective and sensitive behavior against Cu2+ ions (linear range = 0-9 μM and limit of detection = 1.34 μM). Moreover, the CDs were utilized in fluorescent ink in anti-counterfeiting measures. Because of their low cytotoxicity and good biocompatibility, the CDs were also successfully utilized in cell imaging. Therefore, the as-prepared CDs have great potential in fluorescence sensing, anti-counterfeiting, and bioimaging.

De Novo Design and Characterization of Amphiphilic Peptides with Basic Side Chains for Tailored Interfacial Chemistries.

Lysine-leucine (LK) peptides have been used as model systems and platforms for 2D material design for decades. LK peptides are amphiphilic sequences designed to bind and fold at hydrophobic surfaces through hydrophobic leucine side chains and hydrophilic lysine side chains extending into the aqueous subphase. The hydrophobic periodicity of the sequence dictates the secondary structure at the interface. This robust design makes them ideal candidates for controlling interfacial chemistry. This study presents the de novo design and characterization of two novel peptides: LRα14 and LHα14, which substitute lysine with arginine and histidine, respectively, in the helical LKα14 sequence. This modification is intended to expand the LK peptide platform to a new basic interfacial chemistry. We explore the stability of the new LRα14 and LHα14 designs with respect to changes in pH and salt concentration in bulk solution and at the interface using circular dichroism (UV-CD) and vibrational sum-frequency generation spectroscopy, respectively. Notably, the structural stability of the peptides remains unaffected across a wide range of pH and ionic strength values. At the same time, the variation of side-chain chemistry leads to a wide spectrum of interfacial water structures. By extension of the LK platform to include arginine and histidine, this study broadens the toolbox for designing tailored interfacial chemistries with applications in material and biomedical sciences.

Antihyperuricemia Potential of Ethyl Acetate Fraction from Ethanolic Stem Extract of Arcangelisia flava

Arcangelisia flava, with its secondary metabolites in flavonoids, has shown promising potential as an alternative treatment for hyperuricemia. The study aimed to determine the effectiveness of the ethyl acetate fraction from the ethanolic stem extract of Arcangelisia flava in inhibiting xanthine oxidase. This research, conducted at the Medical Basic Chemistry Laboratory Universitas Sriwijaya in September–December 2022, used in vitro study methods. The stem of Arcangelisia flava was extracted by maceration using ethanol. The ethanolic stem extract of Arcangelisia flava was then fractionated using n-hexane and ethyl acetate. The ethyl acetate fraction and ethanolic extract of Arcangelisia flava were measured to inhibit the xanthine oxidase using UV-vis spectrophotometry with allopurinol as a comparison. The IC50 was calculated by linear regression. The ethanol extract and ethyl acetate fraction have flavonoids, alkaloids, terpenoids, and quinones. The IC50 value of the ethanol extract was 30.04 ppm, the ethyl acetate fraction was 23.99 ppm, and the allopurinol was 17.16 ppm. The ethyl acetate fraction inhibited xanthine oxidase better than the ethanol extract. The study's significant finding is that the ethyl acetate fraction of the ethanolic stem extract of Arcangelisia flava strongly inhibits xanthine oxidase, offering a potential new avenue for treating hyperuricemia.

Application of Growth Record Evaluation in Classroom Teaching in Medical Universities -- Taking the Course of Medical Basic Chemistry as an Example

Growth record evaluation is an educational evaluation method based on the characteristics of the digital age, integrating information technology and evaluating students from both horizontal and vertical dimensions throughout the entire process and in all aspects. This article introduces the design and practice of growth record evaluation in Basic Chemistry for medical students. It is shown that this evaluation method can compensate for the problems of traditional evaluation methods and is conducive to promoting the all-round development of students.

Geoelectrical and seismoelectric mapping of subsurface pollution in a closed landfill near the Tongo Bassa and Ngongue river, Douala Cameroon

Located in Douala V (Cameroon), Makepé Missoké is a lowland area that is influenced by the Tongo Bassa and Ngongué rivers. The site has a closed dumpsite, that operated from the 1975’s to 2003 for the disposal and storage of domestic waste produced in Douala. Geoelectric profiling (ERT) coupled with seismo-electric imaging was used to characterize the shallow aquifer of the Douala subbasin and map subsurface pollution. Fourteen geoelectrical profiles were deployed between June and August 2018 and March 2019. Along these lines, 49 sets of seismo-electric point data were collected in December 2021. A total of 118 wells drilled (2018) were used to obtain water level and topographic data. The aquifer geometry, hydraulic characteristics, permeability, lithology and leachate plume extent were determined. This survey enables us to visualize waste infiltration and migration within Makepé. The drilled wells indicate that the main lithologies observed are clay, sandy clay, sand, clayey sand and gravel. The leachate plume observed after processing the electric profiles had a resistivity signature of ≤ 10 Ωm, and high electrical conductivity are observed in some wells. The leachate migrates within the subsurface along a northwest‒southwest trend, where ground water pollution is observed due to leachate infiltration. This infiltration resulted in poor water quality indices in some collected samples. Such pollution is common in unconfined aquifers (< 50 m) due to the absence of a confining layer at the landfill. An increase in resistivity values with depth toward the northeast direction indicates progressive vertical dilution during leachate mineralization. This study integrated geoelectric and seismo-electric tomography with basic water chemistry analysis to effectively characterize the groundwater within the phreatic Quaternary/Mio-Pliocene aquifers of the Douala basin.

Optimization of basic chemistry learning: Validation of stem-based problem-based learning materials for chemical equilibrium

Background: The objective of this study is to create Basic Chemistry learning materials focused on the topic of Chemical Equilibrium using a STEM Problem-Based Learning approach. Effective learning is necessary to enhance students' understanding of complex chemistry concepts. Method: This study adopts the STEM Problem-Based Learning material development method, utilizing the ADDIE model, which consists of five steps: analysis, design, development, implementation, and evaluation. After the development process, the learning materials were assessed through an expert review stage. Evaluation was conducted to assess the validity of the design, pedagogical validity, and content validity using Aiken's coefficient as an indicator. Results: The expert review evaluation results showed high Aiken's coefficients: 0.98 for design validity, 0.95 for pedagogical validity, and 0.96 for content validity. These findings confirm that the developed learning materials comprehensively meet validity standards. Conclusion: Based on these evaluation results, it can be concluded that the developed Basic Chemistry learning materials, particularly on Chemical Equilibrium using the STEM Problem-Based Learning approach, meet the validity criteria. Therefore, these learning materials are considered suitable for use in the Basic Chemistry learning process. Novelty/Originality of this study: This study integrates the STEM Problem-Based Learning approach into developing Basic Chemistry learning materials, specifically on Chemical Equilibrium. Using the ADDIE model and comprehensive validation, this study presents a new framework for designing learning materials that simultaneously meet design, pedagogical, and content standards.

Bone Cement in Adult Hip and Knee Reconstruction: A Review of Commercially Available Options and Clinical Outcomes.

Polymethyl-methacrylate (PMMA) bone cement is used extensively in hip and knee arthroplasty. A thorough understanding of the basic chemistry underlying PMMA is important for orthopaedic surgeons because this underscores the specific way bone cement is used during surgery. Recently, clinical research has shed light on the various types of PMMA regarding the viscosity of the mixture and the effect of cement additives. These variations in composition may alter the clinical efficacy of implanted bone cement in hip and knee arthroplasty. Understanding these key differences will allow the surgeon to tailor the PMMA composition as needed to maximize outcomes of hip and knee arthroplasty. This review will summarize the preclinical feature of PMMA, evaluate current and past commercially available bone cement options, analyze preclinical results and clinical outcomes of various bone cement types, and highlight future areas of research.

Peran Media Pembelajaran Kreatif Dalam Peningkatan Keterampilan Sains Anak Usia Dini di Kelurahan Kebonsari, Kecamatan Citangkil, Kota Cilegon

The lava lamp exercise with the children of kebonsari urban village, citangkil sub-district is a fun and educational activity that involves making simple lava lamps using materials easily found at home. This study aims to explore the children's experience of the lava lamp experiment, and its impact on their understanding of basic chemistry concepts, and chemical interactions. Through a teaching approach based on simple science experiments and participatory observation, children were given the opportunity to experiment with a mixture of oil, water, and coloring agents to create interesting visual effects in their own lava lamps. The results showed that this practice not only increased children's interest in science, but also strengthened collaborative skills, and understanding of basic experimental concepts. This experiment highlights the importance of experiential and interactive learning approaches in developing childrens I nterest in science.

Project Based Learning (PjBL) in Chemistry Learning: Systematic Literature and Bibliometric Review 2015 - 2022

Education is important to form an intelligent and competitive generation. Project Based Learning (PjBL) offers relevant and interactive learning, recognized by Grant (2002) as a student-centered model. PjBL creates a constructivist environment, developing content understanding and skills, such as communication, time management, research and critical thinking. This research focuses on the application of PjBL in chemistry learning, aiming to find out the results of previous research. This research uses Systematic Literature Review (SLR) and bibliometric review as methods. SLR is considered a systematic and transparent method of collecting, synthesizing and assessing study findings on a topic. The process includes planning (research identification), implementation (literature search and selection), and reporting (synthesis of findings). The research question (RQ) focuses on the application of Project Based Learning (PjBL) in chemistry learning. Twenty journals were selected, mostly from Scopus, with criteria ranging from 2015-2020. The analysis showed that 13 journals met the criteria, and a bibliometric review was then carried out on these journals. The research results show that PjBL focuses on skill development, learning innovation, and the impact on student understanding and participation. The research implications highlight the importance of the PjBL model to improve the learning process and better learning tools. The results revealed a wide variety of methods and samples. Six studies focused on the influence of PjBL, critical thinking abilities, psychomotor skills, problem solving, creativity, cognitive achievement, and teamwork. This framework generally involves students' innovative learning and laboratory experiments. Chemistry concepts include analytical, physical, environmental, basic, and organic chemistry. Data collection and analysis tools serve as benchmarks for future research and implications.

Learning with NanoKid: line-angle formula, chemical formula, molecular weight, and elemental analysis

Abstract The conversion from line-angle formula to chemical formula often poses a challenge for first-year nonchemistry majors. To address this, the authors developed an engaging exercise lecture that encompasses the conversion process and related chemistry concepts, including molecular weight and elemental analysis. Initially, the instructor reviews basic chemistry concepts with the students. Subsequently, students construct a NanoKid structure model using transistors and red LEDs connected by plastic tubes, representing carbon and oxygen atoms, respectively. By referencing their models, students identify the chemical formula of NanoKid, calculate its molecular weight, and perform elemental analysis under the guidance of the instructor. Additionally, they estimate the scale of the NanoKid model relative to the actual NanoKid molecule. The exercise promotes peer review among students and is completed within approximately 45 min. A post-lecture questionnaire revealed that the exercise was well-received by the students.

Corrigendum: Commentary: Evolving a mitigation of the stress response pathway to change the basic chemistry of life

Corrigendum: Commentary: Evolving a mitigation of the stress response pathway to change the basic chemistry of life

Effect of Cap Management Frequency on the Phenolic, Chromatic, and Sensory Composition of Cabernet Sauvignon Wines from the Central Coast of California over Two Vintages.

Cabernet Sauvignon from the California Paso Robles AVA was processed with a contrasting array of cap management frequencies, consisting of punch-down (PD) frequencies (0, 1, 2, and 3 PD/day) over two vintages, one of which the fruit was harvested at two contrasting maturity levels. Wines followed with up to 3 years of bottle aging for basic and phenolic chemistry, and the wines of the second harvest of 2020 were submitted to sensory analysis. There were almost non-existent effects due to the frequency of punch downs on parameters such as ethanol, pH, titratable acidity, lactic acid, and glucose + fructose. In 2019, the chromatic differences between different PD regimes were subtle, and minor effects of the punch-down frequency were observed for tannins and total phenolics. During the early stages of alcoholic fermentation, higher levels of all anthocyanin classes were observed in 1 PD wines and the lowest levels in 0 PD wines. The anthocyanin content of the wines of the first harvest (unripe) was 27% higher than that of the wines of the second harvest (ripe), but these differences disappeared after 3 years of bottle aging irrespective of the vintage and harvest date. Acylated anthocyanins were preferentially lost during aging, especially in 2019 wines and, to a lesser extent, in 2020 wines. In 2020, the polymeric pigment content of the wines of the second harvest was higher than in the wines of the first harvest, with 3 PD wines showing higher polymeric pigments and yellow hues than 0 and 2 PD wines after 3 years of bottle aging. Sensory analysis of the second harvest of the 2020 wines showed that the wines of all four PD regimes were perceived as drying, signifying they were perceived as equally astringent, which is consistent with comparable tannin levels on said wines. The perception of bitterness increased with the frequency of punch downs; thus, 3 PD wines showed the highest bitterness perception. It was concluded that in sufficiently warm fermentations and small volumes, phenolic extraction occurs regardless of fruit maturity and under conditions of minimum mixing.

A Systematic Review: How the Implementation of Collaborative Learning in Chemistry?

This research aims to determine what chemical materials are commonly used in collaborative learning and what methods/modes/approaches are used in collaborative learning in chemistry classes. The research method used is a systematic literature review (SLR) by analysing relevant research results from the Google Scholar and ERIC databases of 20 articles based on their suitability with the research theme within the last eight years (2016-2023). Through the SLR method, articles are reviewed systematically by following the steps that have been determined. The results of this systematic literature review (SLR) chemical material commonly used in collaborative learning is basic chemistry at the senior high school and university level, then the models/methods/approaches used in collaborative learning are inquiry-based collaborative learning, flipped classroom, and game-based collaborative learning.

Enhancing self-learning skills and quality through formative actions and feedback within chemistry classes in the laboratory – A useful model

In here a novel method is described to improve student success rates in a first-year basic chemistry theoretical/practical hybrid course (n = 31 students) by implementing simple ways of formative assessment. This to reduce student dropout rates following the philosophy of encouraging students’ self-control. Essential is to train first-year bachelor students in their self-learning skills and to enhance their evaluative judgment. As a result, students are able to provide better quality of the assessment products at the end of the course. In practice the course is redesigned and intervention tools are integrated at multiple levels throughout the course. The lecturers’ role was adapted to a coaching role, thereby introducing low-effort personalized micro-interventions to meet the personalized needs of students. To clarify these learning needs for students, awareness of the quality desired for the final assessment products is important. Awareness was improved by providing examples of varying quality and introducing multiple peer- and self-assessment moments during the course. The final evaluation of the course examination products showed that the quality of the laboratory notebook was substantially higher after following this approach. Additionally students learned other important skills such as self-learning skills, collaborating in practical work and giving and receiving feedback. Unexpectedly, the high perceived lecturers’ workload decreased. The work presented here provides a novel approach in the form of a model and a practical blueprint with tools for a practical chemistry course design which develops students’ self-learning skills thereby substantially improving student success rates. In our example course, the ultimate student success rate increased form 83 % to 95 % after using this novel approach.

Responsive materials nanoarchitectonics at interfaces

AbstractAdvanced materials could perform functions in response to external stimuli. These are responsive materials. In order for us to develop advanced functional systems with a good responsive nature, we need to create a methodology that goes one step further. It is the artificial architecture of functional material systems based on the knowledge of nanotechnology. The task will be fulfilled by the new concept of nanoarchitectonics. Nanoarchitectonics integrates nanotechnology with various material sciences, basic chemistry, microfabrication techniques, and biological processes to architect functional material systems from atomic, molecular, and nanomaterial units. This review will deal with the nanoarchitectonics of responsive materials related with phenomena at interfaces. In order to demonstrate the effectiveness of responsive materials nanoarchitectonics at interfaces for functional systems of various sizes, this review article is organized by size for various functional systems. Specifically, this review has grouped them into (i) molecular level response, (ii) nanodevice level response, (iii) material level response, and (iv) living cell level response. If the social demand for these materials is fully recognized, such development is expected to efficiently progress. This review article would play a role in stimulating such development.

The need analysis for computational chemistry based learning media atomic structure and chemical bonding basic chemistry courses

The need analysis for computational chemistry based learning media atomic structure and chemical bonding basic chemistry courses

Review of Chemistry Learning Strategy Based on Process Oriented Guided Inquiry Learning (POGIL)

This study aimed to review the application of Process Oriented Guided Inquiry Learning (POGIL) in chemistry learning strategies by analysing reputable international journal documents between 2012 and 2022. The method used was a literature study with 47 articles on POGIL-based chemistry learning strategies. The results of the analysis showed that POGIL-based chemistry learning strategies applied to college students and high school students can improve learning achievement, self-efficacy, critical thinking, problem-solving, science processing skills, representational abilities, multiple intelligences and other skills. The chemical study materials were about basic chemistry, organic chemistry, physical chemistry, biochemistry and inorganic chemistry. In addition, several researchers used the POGIL syntax at different stages from the original idea of Moog and Spencer because the design of POGIL activities adapted to the skills to be improved. Furthermore, there are limitations to the application of POGIL-based chemistry learning strategies, which require more time to implement. Keywords: POGIL, chemistry, learning strategies