Base isolation is among the most effective techniques for safeguarding buildings against earthquakes. Similar to non-isolated buildings, the seismic performance of a base-isolated building can vary not only due to the inherent record-to-record variability in earthquake ground motions but also the non-negligible influence of uncertainties associated with structural properties. Introducing an isolation layer of isolation bearings and energy dissipators to the building further adds to the source of uncertainties, raising the question regarding the reliability of base isolated buildings. This study proposed a methodology that employs the probability density evolution method (PDEM) with local time grid refinement to evaluate the reliability of a base-isolated structure and its non-isolated counterpart under earthquakes of various magnitudes and fault distances. It allows for simultaneously considering the uncertainties of various sources in the reliability analyses with affordable computational cost, including those of the ground motions, of the structural nonlinearity, and of the ultimate states that define the reliability. The results show that the base-isolated building exhibits much higher reliability than its non-isolated counterpart in all cases even if the ultimate behavior such as the isolator fracture or the impact to the retaining wall is considered. The added source of uncertainties in the isolation layer does not exhibit a notable impact on the reliability. In contrast, the seismic reliability of base-isolated buildings is much less sensitive to structural uncertainties than that of their non-isolated counterparts.
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