Baleanu Derivative Research Articles

Modeling and analysis of Hepatitis B dynamics with vaccination and treatment with novel fractional derivative.

These days, fractional calculus is essential for studying the dynamic transmission of illnesses, developing control systems, and solving several other real-world issues. In this study, we develop a Hepatitis B (HBV) model to observe the dynamics of vaccination and treatment effects to control the disease by using novel fractional operator. Modified Atangana-Baleanu-Caputo (MABC) is a new definition of the used derivative that is based on a modification of the Atangana and Baleanu derivatives. By employing the MABC fractional derivative, which incorporates the concepts of non-locality and memory effects our model captures the complex dynamics of HBV transmission more accurately than traditional models. An objective of this study is to analyze the effect of immunization and treatment techniques on the course of the hepatitis B virus, with a particular focus on the changing order of differentiation. Thereby, our paper deals with the stability analysis, positiveness, existence and uniqueness of the solution and simulations. Analysis of reproductive number R0 with the impact of different parameters is also treated. The proposed model's existence and uniqueness findings are examined through the use of Banach's fixed point and Leray-Schauder nonlinear alternative theorems. The equilibria for the models are determined to be globally stable using Lyapunov functions. The simulations for certain parameters are achieved by applying the Lagrange interpolation for the numerical computations and also the results are compared with the ABC operator results. The model is validated using numerical simulations, which are also used to assess how well different intervention techniques work to lower the impact of HBV infection and prevent its spread throughout the community. The results of this research assist in developing public health policies intended to lower the incidence of HBV infection worldwide and offer insightful information about how well treatment and vaccination strategies work to prevent HBV disease.

Numerical estimation of the fractional advection–dispersion equation under the modified Atangana–Baleanu–Caputo derivative

The transport of contaminants is a crucial environmental issue, and accurate modeling of this phenomenon is vital for developing effective strategies for its management. In this study, We introduce a non-integer model of the advection–dispersion problem arising in the transport of contaminants. The used derivative is described in the modified Atangana–Baleanu–Caputo (MABC) sense which is a new definition based on an extension of the Atangana and Baleanu derivatives. We employ discrete Chebyshev polynomials to gain the numerical solution of the considered equation. First, we generate a new operational matrix through discrete Chebyshev polynomials properties and proposed derivative. Next, via discrete Chebyshev polynomials and the operational matrix, we gain an algebraic system whose solutions are easily obtained. Finally, we solve some examples and compare the results with those obtained from other numerical methods to confirm the practicality and accuracy of the suggested scheme.

A study of behaviour for immune and tumor cells in immunogenetic tumour model with non-singular fractional derivative

Abstract Mathematical biology is one of the interesting research area of applied mathematics that describes the accurate description of phenomena in biology and related health issues. The use of new mathematical tools and definitions in this area of research will have a great impact on improving community health by controlling some diseases. This is the best reason for doing new research using the latest tools available to us. In this work, we will make novel numerical approaches to the immunogenetic tumour model to using differential and integral operators with Mittag-Leffler law. To be more precise, the fractional Atangana- Baleanu derivative has been utilized in the structure of proposed model. This paper proceeds by examining and proving the convergence and uniqueness of the solution of these equations. The Adam Bashforth’s Moulton method will then be used to solve proposed fractional immunogenetic tumour model. Numerical simulations for the model are obtained to verify the applicability and computational efficiency of the considered process. Similar models in this field can also be explored similarly to what has been done in this article.