Introduction. Patients with transferred a new coronavirus infection, as a rule need in a rehabilitation. It is necessary to develop clinical recommendations for this group of patients. Medical rehabilitation during the COVID-19 pandemic should include all components of rehabilitation measures aimed at rapid recovery of vital body functions, improving the quality of life of patients and preventing complications. The aim of study is to identify the most effective methods of rehabilitation of patients with lung damage of varying severity caused by a new coronavirus infection. Assessment of rehabilitation potential depending on age, gender, and severity of lung tissue damage. Materials and methods. The article describes the experience of rehabilitation and rehabilitation treatment of 40 patients after acute infection caused by the SARS-CoV-2 virus, which was carried out on the basis of the neurological occupational pathology Department of the Burnazyan State Medical Center. Results. To determine the volume of rehabilitation treatment, each patient was tested using special scales and questionnaires that allow assessing the patient's somatic status, physical activity tolerance, cognitive functions, and the presence of affective disorders. Testing was performed at the patient's admission to the hospital and on the 12th day, which helped to assess the dynamics of recovery. To achieve the maximum effect of the work done, we have organized an individual comprehensive multidisciplinary approach to each patient, including a group of specialists, such as a therapist, pulmonologist, neurologist, rehabilitologist, physiotherapist, psychologist, physical therapy instructor. Against the background of rehabilitation and rehabilitation treatment, there was a positive dynamics in the condition of patients, in the form of an increase in tolerance to physical activity according to scales, questionnaires, and functional tests in 95%, improvement in saturation indicators in 90%, and affective disorders were completely corrected in 85% of patients. Subjectively, 100% of patients report an improvement in their health status. Conclusions. Thus, despite the timely treatment received in the acute period of the disease, a very important stage in the treatment of patients is rehabilitation in the long-term period.