Baby-Friendly Hospitals (BFH) in the United States (U.S.) are associated with higher breastfeeding initiation rates. Breastfeeding is associated with a myriad of favorable health outcomes for both mother and child. However, few studies have examined the impact of breastfeeding support resources, like BFH, on breastfeeding initiation among minority groups. The objective of this study is to evaluate the association between birth at a BFH and the breastfeeding initiation in Florida. A retrospective exploratory analysis of BFH and birth certificate data (n=3,321,022 ) from 2004-2022 from Florida was conducted. A logistic regression model was fit to examine the main and interaction effects of race/ethnicity and birth at a BFH on breastfeeding initiation. Time was included as a sequential variable to adjust for temporal effects. Covariates known to impact breastfeeding initiation rates, including maternal education and prenatal care utilization, were included in multivariate analyses. Of births at a BFH, 89% of mothers initiated breastfeeding. Comparatively, of the births at a non-BFH, 84% of mothers initiated breastfeeding. Giving birth at a BFH increased the odds of breastfeeding initiation by at least 42% (OR = 1.42, CI: 1.38-1.45, p <0.001, Hispanic White mothers) in unadjusted models and 10% (OR = 1.10, CI: 1.03-1.17, p = 0.004, other non-Hispanic mothers) in adjusted models. However, BFH may have differential effects by maternal race and ethnicity. In the multivariate model adjusting for relevant covariates, non-Hispanic Black mothers who gave birth at a BFH were 27% less likely to initiate breastfeeding compared to mothers that gave birth at a non-BFH (OR = 0.73, CI: 0.61- 0.88, p < 0.001; interaction term for BFH*maternal race/ethnicity). Similar trends were observed for Hispanic Black, Hispanic White, and other non-Hispanic mothers. Giving birth at a BFH is associated with greater odds of breastfeeding initiation. However, when considering the race and ethnicity of mothers, these odds significantly decline, indicating a need to further explore the barriers that may preclude non-Hispanic Black and Hispanic moms from receiving the same benefits of BFH.