aza-Michael Reaction Of Amines Research Articles

Water hyacinth ash: an efficient green catalyst for the synthesis of β-amino carbonyl/nitrile compounds by aza-Michael reaction at room temperature

Water hyacinth ash is found to be an efficient and reusable catalyst for the synthesis of β-amino carbonyl/nitrile compounds by aza-Michael reaction of amines with α,β-unsaturated compounds at room temperature under solvent free condition. Due to low cost of the catalyst, good activity, ease of handling and easy recovery with high yields of the products in short reaction time, easy workup procedure, mild reaction condition, the protocol is highly applicable in synthetic organic chemistry.

Supramolecular Assemblies in Ionic Liquid Catalysis for Aza-Michael Reaction

Supramolecular assemblies formed by a relay of cooperative hydrogen bonds and charge-charge interactions have been identified/characterized by (+ve) ESI and MALDI-TOF-TOF MS and MS-MS studies during the aza-Michael reaction of amines with alpha,beta-unsaturated carbonyl compounds in the presence of ionic liquids (ILs) digging out the role of catalysis by ILs, forming the basis of rational design/selection as organocatalysts, and offering a diagnostic model to predict/rationalize the selectivity of the aza-Michael reaction in a competitive environment.

Polyaniline supported CuI: An efficient catalyst for C–N bond formation by N-arylation of N(H)-heterocycles and benzyl amines with aryl halides and arylboronic acids, and aza-Michael reactions of amines with activated alkenes

Abstract Polyaniline supported CuI catalyst was prepared, characterized and effectively used in the N -arylation of N (H)-heterocycles and benzylamines with aryl halides and arylboronic acids and in aza-Michael reaction of amines with activated alkenes. The catalyst was recovered by simple filtration and reused for several cycles with consistent activity.

Polyaniline supported indium chloride: A reusable catalyst for organic transformations in water

Polyaniline supported indium(III) trichloride (PANI-In) catalyst was prepared and thoroughly characterized by using FTIR, XPS, scanning electron microscopy-energy dispersive X-ray analysis (SEM-EDX) and ICP-AES. Thus, the synthesized catalyst was efficiently used in the aza-Michael reaction of amines with electron-deficient olefins and aza-Diels-Alder reaction of cyclic enol ethers with aromatic amines in water. Moreover, the catalyst was easily recovered by simple filtration and reused for several cycles with consistent activity.

Amberlyst-15: An efficient reusable heterogeneous catalyst for aza-Michael reactions under solvent-free conditions

The aza-Michael reactions of amines with α,β-unsaturated carbonyl and nitrile compounds have efficiently been carried out at room temperature using Amberlyst-15 as a heterogeneous reusable catalyst. The products were formed in short reaction times and in high yields.