Traditional Ayurvedic Medicine Research Articles

Formulation and Evaluation of Herbal Churna for Constipation

Formulation and evaluation of herbal churna for constipation. • Churna is a very famous ayurvedic medicine for constipation. It is a traditional ayurvedic medicine. • The goal of treatment relives the cause of constipation and to promote regular and predictable bowel movement. • Regulates bowel movement. • Relieves frequent and chronic constipation. • Helps to pass stool more smoothly. • churna is a very famous Ayurvedic medicine for constipation. It is not a traditional Ayurvedic medicine. • It is a proprietary Ayurvedic medicine. It means that the formula of Kayam churna is not mentioned in any Traditional Ayurvedic text books. • The manufacturer of Churna, Sheth Brothers, formulated a combination of few Ayurvedic herbs that benefit in constipation, blended them into powder form and labelled it as churna. • As the standardization of herbal formulation is great concern for its safety and efficacy for that reason this work is aimed to formulation comparative evaluation of churna with marketed product. Churna, a traditional Ayurvedic formulation, has been used for centuries to treat constipation. The powder, composed of a blend of natural herbs and ingredients, stimulates bowel movements, softens stools, and relieves straining during defecation. With its natural and safe composition, Churna offers a cost-effective and minimally invasive solution for managing constipation. These abstract reviews the ingredients, preparation, and pharmacological properties of Churna, highlighting its potential as a natural remedy for constipation relief..

Quality Studies on Cynometra iripa Leaf and Bark as Herbal Medicines.

Cynometra iripa Kostel. is a Fabaceae species of mangrove used in traditional Ayurvedic medicine for treating inflammatory conditions. The present study aims to establish monographic botanical and chemical quality criteria for C. iripa leaf and bark as herbal substances and to evaluate their in vitro antioxidant potential. Macroscopic and microscopic qualitative and quantitative analyses, chemical LC-UV/DAD-ESI/MS profiling, and the quantification of key chemical classes were performed. Antioxidant activity was evaluated by DPPH and FRAP assays. Macroscopically, the leaf is asymmetrical with an emarginated apex and cuneate base. Microscopically, it shows features such as two-layered adaxial palisade parenchyma, vascular bundles surrounded by 3-6 layers of sclerenchyma, prismatic calcium oxalate crystals (5.89 ± 1.32 μm) along the fibers, paracytic stomata only on the abaxial epidermis (stomatal index-20.15), and non-glandular trichomes only on petiolules. The microscopic features of the bark include a broad cortex with large lignified sclereids, prismatic calcium oxalate crystals (8.24 ± 1.57 μm), and secondary phloem with distinct 2-5 seriated medullary rays without crystals. Chemical profile analysis revealed that phenolic derivatives, mainly condensed tannins and flavonoids, are the main classes identified. A total of 22 marker compounds were tentatively identified in both plant parts. The major compounds identified in the leaf were quercetin-3-O-glucoside and taxifolin pentoside and in the bark were B-type dimeric proanthocyanidins and taxifolin 3-O-rhamnoside. The total phenolics content was higher in the leaf (1521 ± 4.71 mg GAE/g dry weight), while the total flavonoids and condensed tannins content were higher in the bark (82 ± 0.58 mg CE/g and 1021 ± 5.51 mg CCE/g dry weight, respectively). A total of 70% of the hydroethanolic extracts of leaf and bark showed higher antioxidant activity than the ascorbic acid and concentration-dependent scavenging activity in the DPPH assay (IC50 23.95 ± 0.93 and 23.63 ± 1.37 µg/mL, respectively). A positive and statistically significant (p < 0.05) correlation between the phenol content and antioxidant activity was found. The results obtained will provide important clues for the quality control criteria of C. iripa leaf and bark, as well as for the knowledge of their pharmacological potential as possible anti-inflammatory agents with antioxidant activity.

The Phytochemical Analysis and Anthelmintic Potential of Celastrus paniculatus Seed: An In-Vitro Assessment

As the quality requirements are predicated on appropriate raw material selection, standardization is important to the development of phytopharmaceuticals of standard quality. A traditional Ayurvedic medicine plant, Celastrus paniculatus Wild (Celastraceae), has been used for millennia as a sedative, antiepileptic, analgesic, anti-inflammatory, and memory-enhancing drug. For rheumatism, gout, paralysis, and leprosy, a decoction of seeds is prescribed. The current study looks at morphological and microscopic characteristics, ash value, extractive values, and phytochemical assessments, which include a qualitative chemical analysis of the active ingredients. It was found that different seed extracts had varying degrees of anthelmintics.

TOPICAL APPLICATIONS IN AYURVEDA FOR THE MANAGEMENT OF ANAL FISSURES: A REVIEW

Anorectal fissures are a common ailment where the lining of the anal canal breaks or fractures painfully. Using a variety of topical treatments, traditional Ayurvedic medicine provides a comprehensive approach to control anal fissures. The purpose of this thorough analysis is to assess the efficacy of various Ayurvedic therapies for anal fissures, with an emphasis on the length of therapy and the rates of recovery linked to these interventions. A wide variety of Ayurvedic topical treatments, such as herbal ointments, medicinal oils, and formulations enhanced with natural constituents, are methodically analysed in this paper. To study the effect of various local applications in Ayurveda on treating fissures-in-ano. The text was collected from the classical Ayurvedic literature. Different research papers published in national and international journals were analysed systemically to determine their effectiveness in terms of duration of treatment and healing rate. According to the aforementioned study, numerous clinical trials were carried out in Ayurveda to demonstrate the efficacy of different local applications for the treatment of anal fissures, with a promising success rate. In three to four weeks, most of the fissures were observed to have fully healed. This study suggests that surgery can be avoided if anal fissure patients receive treatment in the initial stage with topical applications like ghrita, taila, malahara, pichu, guda varti, or guda basti.

Prakriti Chatbot using NLP

This literature explores the connection of traditional Ayurvedic ideas and modern technologies, providing a new perspective. Evaluate Ayurvedic Prakriti using Prakriti Bot, an AI-powered chatbot. Ayurveda classifies individuals into three prakriti types: Pitta, Kapha, and Vata. We offer a website with a chatbot to swiftly determine an individual's ayurvedic constitution, as traditional prakriti evaluation can be time-consuming. Prakriti bot simplifies evaluation by providing personalised health recommendations and Ayurvedic teaching materials. The website bridges the gap between traditional ayurvedic medicine and modern healthcare by enabling regional language option and personalised report generation.

Comparative Study on the Effect of Bacopa monniera and Omega3 Fatty Acids on the Cortisol Hormone Level in Cold Stress Induced Wistar Albino Rats

In recent years, researchers have identified several natural compounds that could potentially help to retard mental stress. Extracts of Bacopa monniera (BM), a traditional ayurvedic medicine and omega3 faffy acids (OFA) have been reported to enhance effects mental functions by combating the stress. However, there is still an lacunae studies on which of those two drugs has better results on cortisol hormonal changes due to stress. The current study aimed to compare the effects of BM and omega3 fatty acids on cold stress induced Wistar rats. We divided the animals into seven groups. Group I was control in which rats were kept under ideal laboratory conditions, Group II was given cold water swim stress for a period of one month after which the rats were sacrificed for hormonal assay, Group III in which cold water swim stress given for a month followed by oral administration of normal saline as vehicle for a month, Group IV and V in which cold water swim stress given for a month followed by oral administration of BM extracts 40mg/kg and 80mg/kg respectively as treatment for a month. Group VI and VII includes cold stress followed by oral gavages of OFA 60mg/Kg of Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) for 2 weeks (short-term model) and 4 weeks (long term model) respectively. After the treatment period blood was collected and cortisol assay was done. The data were compared with those of control rats. The results showed an increase in the cortisol level in the stressed group of rats when compared to the treatment group. These results indicate that oral administration of high dose of BM and long-term administration of OFA improves the cortisol level and helps in controlling the stress in rats.

Effect of Bacopa monniera on the Level of Cortisol Hormone in Forced Cold Water Swim Stress Induced Wistar Albino Rats

The human brain remains a mystery even after years of research into the biological processes underlying its specific actions. In recent years, researchers have identified several natural compounds that could potentially help to retard mental deterioration. Extracts of Bacopa monniera, a traditional ayurvedic medicine, have been reported to have memory-enhancing effects in animals. However, there are no studies on bp in cold stress induced neuronal changes in hippocampus have been explored. The current study examined the effects of standardized extract of Bacopa monniera, on Wistar rats. We divided the animals into 4 groups. Group I was control in which rats were kept under ideal laboratory conditions, Group II was given cold water swim stress for a period of one month after which the rats were sacrificed for histological studies to study the changes in the hippocampus caused by cold stress, Group III in which cold water swim stress given for a month followed by oral administration of normal saline as vehicle for a month, Group IV in which cold water swim stress given for a month followed by oral administration of Bacopa monniera, extracts 40mg/kg treatment for a month. Group V in which cold water swim stress given for a month followed by oral administration of Bacopa monniera, extracts 80mg/kg treatment for a month. After the treatment period blood was collected and cortisol assay was done. The data were compared with those of control rats. The results showed an increase in the cortisol level in the stressed group of rats when compared to the treatment group. These results indicate that oral administration of Bacopa monniera, extract improves the cortisol level and helps in controlling the stress in rats.

Elucidating the anti-cancer potential of Cinnamomum tamala essential oil against non-small cell lung cancer: A multifaceted approach involving GC-MS profiling, network pharmacology, and molecular dynamics simulations

Cinnamomum tamala (Buch.-Ham.) T.Nees & Eberm., or Indian Bay Leaf, is a well-known traditional ayurvedic medicine used to treat various ailments. However, the molecular mechanism of action of Cinnamomum tamala essential oil (CTEO) against non-small cell lung cancer (NSCLC) remains elusive. The present study aims to decipher the molecular targets and mechanism of CTEO in treating NSCLC. GC-MS analysis detected 49 constituents; 44 successfully passed the drug-likeness screening and were identified as active compounds. A total of 3961 CTEO targets and 4588 anti-NSCLC-related targets were acquired. JUN, P53, IL6, MAPK3, HIF1A, and CASP3 were determined as hub genes, while cinnamaldehyde, ethyl cinnamate and acetophenone were identified as core compounds. Enrichment analysis revealed that targets were mainly involved in apoptosis, TNF, IL17, pathways in cancer and MAPK signalling pathways. mRNA expression, pathological stage, survival analysis, immune infiltrate correlation and genetic alteration analysis of the core hub genes were carried out. Kaplan-Meier overall survival (OS) curve revealed that HIF1A and CASP3 are linked to worse overall survival in Lung Adenocarcinoma (LUAD) cancer patients compared to normal patients. Ethyl cinnamate and cinnamaldehyde showed high binding energy with the MAPK3 and formed stable interactions with MAPK3 during the molecular dynamic simulations for 100 ns. The MM/PBSA analysis revealed that van der Waals (VdW) contributions predominantly account for a significant portion of the compound interactions within the binding pocket of MAPK3. Density functional theory analysis showed cinnamaldehyde as the most reactive and least stable compound. CTEO exhibited selective cytotoxicity by inhibiting the proliferation of A549 cells while sparing normal HEK293 cells. CTEO triggered apoptosis by arresting the cell cycle, increasing ROS accumulation, causing mitochondrial depolarisation, and elevating caspase-3, caspase-8 and caspase-9 levels in A549 cells. The above study provides insights into the pharmacological mechanisms of action of Cinnamomum tamala essential oil against non-small cell lung cancer treatment, suggesting its potential as an adjuvant therapy.

Gulf war toxicant-induced effects on the hippocampal dendritic arbor are reversed by treatment with a Withania somnifera extract.

Gulf War Illness (GWI) is a multi-symptom disorder that manifests with fatigue, sleep disturbances, mood-cognition pathologies, and musculoskeletal symptoms. GWI affects at least 25% of the military personnel that served in Operations Desert Shield and Desert Storm from 1990 to 1991. We modeled Gulf War toxicant exposure in C57BL/6J mice by combined exposure to pyridostigmine bromide (an anti-sarin drug), chlorpyrifos (an organophosphate insecticide), and DEET (an insect repellent) for 10 days followed by oral treatment with Withania somnifera root extract for 21 days beginning at 12 weeks post-exposure. W. somnifera, commonly referred to as ashwagandha, has been used in traditional Ayurvedic medicine for centuries to improve memory and reduce inflammation, and its roots contain bioactive molecules which share functional groups with modern pain, cancer, and anti-inflammatory drugs. Previously, we observed that GWI mice displayed chronic reductions in dendritic arbor and loss of spines in granule cells of the dentate gyrus of the hippocampus at 14 weeks post-exposure. Here, we examined the effects of treatment with W. somnifera root extract on chronic dendrite and spine morphology in dentate granule cells of the mouse hippocampus following Gulf War toxicant exposure. GWI mice showed approximately 25% decreases in dendritic length (p < 0.0001) and overall dendritic spine density with significant reductions in thin and mushroom spines. GWI mice treated with the Ayurvedic W. somnifera extract exhibited dendritic lengths and spine densities near normal levels. These findings demonstrate the efficacy of the Ayurvedic treatment for neuroprotection following these toxic exposures. We hope that the extract and the neuronal processes influenced will open new avenues of research regarding treatment of Gulf War Illness and neurodegenerative disorders.

Identification of authentic Phyllanthus amarus species in India

The Phyllanthus is a plant used in the traditional Ayurvedic Medicine system and has more than 800 species. These species grow in the same area and there are chances of adulteration of other species and, incorrect identification may also lead to wrong reports. This study was attempted by Enovate Biolife Pvt. Ltd. to identify authentic Phyllanthus amarus. The nine raw material samples were collected from different populations/suppliers from various zones of India for the study. All the samples were analysed using microscopic and macroscopic ID, and by using the High Performance Thin Layer Chromatography (HPTLC) fingerprint method. The samples collected from the Central zone (Lucknow PA-08, Uttar Pradesh) and the Southern zone (Coimbatore PA-05, and Chennai PA-09, Tamil Nadu) of India were found to be authentic P. amarus by the mentioned identification methods.

The impact of ashwagandha on sleep quality, anxiety reduction, and stress lowering: comparative analysis of available studies

Introduction and objective: The increasing prevalence of sleep disorders, anxiety, and stress in contemporary society necessitates effective and accessible treatments. Ashwagandha - Withania somnifera (WS), an adaptogenic herb utilized in traditional Ayurvedic medicine, has gained significant attention in recent years for its potential to improve various aspects of health and well-being. This comprehensive review of the scientific literature aims to systematize the current scientific reports regarding the impact of Ashwagandha on enhancing sleep quality, reducing levels of anxiety and stress.&#x0D; &#x0D; Material and Method: In this article, a review of publications available in the PubMed and Google Scholar databases was conducted, with an analysis of clinical and experimental studies focusing on methodology, participant demographics, dosage regimens, and tools for assessing sleep quality, anxiety, and stress levels. Articles were searched using English language terms: "ashwagandha," "Withania somnifera," "influence of sleep quality," "stress," "anxiety."&#x0D; &#x0D; Conclusions: The scientific studies presented indicate the benefits of Ashwagandha supplementation in the context of improving sleep quality, reducing anxiety states, and stress. The results of various studies, including randomized controlled trials and systematic reviews, suggest that Ashwagandha may positively influence these health aspects through its action on the hypothalamic-pituitary-adrenal (HPA) axis11, modulation of neurotransmitters (GABA, serotonin)1, and antioxidative activity2.

Investigation On the Larvicidal Potential of Endophytic Fungi Isolates from Psoralea corylifolia And Leptadenia reticulata Against Aedes Aegypti

Globally, several million peoples are infected with epidemic-prone mosquito-borne diseases like yellow fever and malaria that is transmitted to humans by the bites of infected mosquitoes. Psoralea corylifolia, often known as babchi, is a well-liked herb that has been utilised in traditional Ayurvedic and Chinese medicine for many years for its miraculous abilities to treat a variety of skin conditions and Leptadenia reticulata, also known as Jivanti is an herb that is traditionally used in treating the conditions like malaria, diabetes, and liver disorders. The present study investigated the larvicidal properties of endophytic fungi isolated from Psoralea corylifolia and Leptadenia reticulata against Aedes aegypti. The highest larvicidal activity was seen in Trichodermata viride and Candida albicans species from leaves of L. reticulata was found to be 85.71% and 90.47 at 20 ppm. Likewise, Piriformospora indica and Aspergillus niger species from the leaves of P. corylifolia was found to be 66.66% and 83.33 % respectively. Candida albicans from leaves of L. reticulata and Aspergillus niger from the leaves of Psoralea corylifolia showed the highest mortality percentage was found to be 90.47 and 83.33 at 20 ppm respectively. The present study reveals the determination of optimal, eco-friendly, and selective mosquito larvicidal agents. The development of innovative and affordable medications to combat diseases spread by mosquitoes will be aided by more research on the isolation, characterisation, and determination of the mechanism of action against the selective mosquitos.

Establishment of the mechanism of purification and levigation of green chemistry-assisted biocomposites of red ochre (Gairika): synthesis, characterization, and antibacterial, prebiotic, antioxidant, and antacid activities of the traditional Ayurvedic medicine Laghu Sutashekhara Rasa

Gairika (red ochre) has a long history of influencing human civilization. Gairika is a rich source of nutrients used for reproductive and brain health. Gairika is mentioned as an antacid drug in Indian Ayurvedic medicine under Laghu Sutashekhara Rasa (LSR). However, a detailed study on LSR has not been reported to date. In the present study, LSR was prepared, and a pharmaceutical SOP (standardization procedure) was reported to obtain batch-to-batch reproducibility. LSR was characterized using FTIR, XRD, SEM-EDX, and TGA analyses. LSR was tested in vitro for its antacid activity. Advanced instrumentation revealed that LSR formation produced symmetrical particles (5–8 µm) with kaolin, kaolinite, quartz, goethite, and hematite, along with the phytoconstituents of Goghrita (clarified cow’s butter), Shunthi, and Nagawalli, as confirmed by GC-MS/MS analysis. The FTIR study revealed the formation of a chelating complex of goethite and hematite along with their phytoconstituents. XRD analysis confirmed the presence of kaolin, kaolinite, quartz, goethite, and hematite. Using in vitro antacid experiments, LSR and Shunthi demonstrated significant antacid activity as compared to antacid drugs and standards in the market, such as CaCO3. The DPPH assay revealed IC50 values of 12.16 ± 1.23 mg/mL, which is 0.0029 of Trolox-equivalent antioxidant activity. The inhibition (18 ± 4 mm) against pathogens (S. aureus, E. coli, P. aeruginosa, and B. subtilis) and the prominent growth of gut microbiota-supported strains (S. boulardii, L. paracasei, and L. plantarum) observed on LSR formulation were indicative of LSR application as a prebiotic. Here, the mechanism of purification and levigation mentioned in the classical literature of LSR was established. Overall, purification of Gairika with cow ghee and levigation with Nagawalli may enhance the solubility, bioavailability, and shelf-life of LSR through hydration and co-crystallization mechanisms. This is the first comprehensive report on the pharmaceutical validation of LSR and its characterization. The results of the present study could contribute to the development and reliable reproduction of LSR and the utility of environmental red ochre as a medicine in combination with Shunthi (Zingiber officinale Roxb.), as prescribed under Indian Ayurvedic medicine.

Ayurvedic Management of Ovarian Cyst

Ovarian cyst is commonest problem facing by young women and foremost cause of infertility in women. Sedentary lifestyle, abnormal food habits, stressful life have influences on secretion of female hormones and thereby causing the manifestation of ovarian cyst. Methodology: In this present case study, 18 years old woman patient consulted to the OPD of Kayachikitsa of GAMCH, Bareilly with the complaints of pain in lower abdomen, irregular menses and generalized weakness. Ultrasonography was advised and finding suggestive of right ovarian cyst (37×33mm). She was given combination of traditional herbomineral Ayurvedic medicine for three months 20 days. Result: By the use of combination of traditional Ayurvedic medicines complete resolution of ovarian cyst was noticed in follow up- Ultrasonography. Discussion: This case study highlights on the management of ovarian cyst by Ayurvedic medicine.

A CRITICAL APPRAISAL ON SUVARNA (GOLD) BHASMA

The Ayurveda system of medicine has appreciable antiquity, dating back to about 5000 years B.C. Materia Medica of Ayurveda contains resources in the form of drugs derived from plant, animal, metal, and mineral sources. Gold is found in the form of fine gold dust, red colloidal solution, Suvarnapatra, Suvarnabhasma, Suvarnaparpati, Kharaliya (triturated) formulations, and Sindoorkalpa. These are used in single or in combination form along with Ghrita and Madhu (honey) to enhance Medhya (intellect) and Rasayana (rejuvenation). Bhasmas are Ayurvedic metal-based preparations manufactured through various steps along with the use of certain herbs. Thus converting raw metal into its therapeutic active form known as Suvarna Bhasma. This Suvarna Bhasama is a traditional Ayurvedic medicine that contains nano and colloidal gold particles. In this review article, the author tries to gather all available information on gold that establishes its anti-inflammatory, antimicrobial, anti-carcinogenic, anti-rheumatic and antioxidant properties through published research articles and experimental and clinical studies.

Nadifit: a novel single position pulse based diagnostic system

Both traditional Chinese medicine (TCM) and traditional ayurvedic medicine (TAM) rely on a system of radial pulse diagnostics to assess a patient's health. The doctor or practitioner should place all three fingers on the patient's wrist and feel the styloid processes to detect any changes in the radial pulse. However, finding medical professionals skilled in pulse diagnosis or nadipariksha is becoming increasingly challenging in the current and upcoming generation. One technological approach that could solve this issue once and for all would be to transform objective pulse diagnosis into a subjective process. To automate this procedure, however, three separate sensors must be constructed for three positions in order to capture pulse at varying pulse pressures, which increases the hardware complexity for consumer use. To simplify the process and ensure a correct diagnosis, this study presents an effort to create the smart portable system Nadifit, which takes a single pulse reading from the patient. A single pulse is all that's needed to identify distinctive organ patterns, which can then be analyzed to provide insight into potential health issues. Analogue signals are quantified with the help of a microphone, a transmitter, and a 32-bit microprocessor. The data is acquired with a precision of 10 bits and virtually no electronic or contaminating noise outside of the system. The computer receives the collected pulse signal and does time and frequency domain analysis of the Nadi patterns, shapes, and width to determine the presence of the three ayurveda doshas (Vata, pitta, and kapha) as well as Chinese organ patterns (such as Qi stagnation, yin deficiency, yang excess, etc.). The experimental results demonstrate the effectiveness of the suggested system in identifying dosha, making it highly tailored to the individual patient's health issue. It is also demonstrated that the pulse waveform demonstrates the desired fluctuations in relation to patient age, pressure applied to the sensing element and full vs. empty stomach. Comparisons of stiffness across age groups are also performed. Practitioners, vaidhyas, and medical professionals are used to verify the system's accuracy. Hence, we believe a larger segment of the general public will be able to make use of our technology.

A Review of Taila Varga (Edible Vegetable Oils) According to Bruhat Trayi

Vegetable oils have been used for many centuries in traditional Ayurvedic medicine in India and in Chinese medicine for their therapeutic properties. The purpose of this article is to inform readers about the characteristics of edible oil as described in Ayurveda, with particular emphasis on Charak Samhita, Sushruta Samhita, and Ashtanga Hridaya. Literature about nutrition and dietetics was studied in books, journals, and research engines. The main components of vegetable oils are sesame, coconut, groundnut, sunflower, soybean, palm, safflower, and mustard oils. Many other oils used as essential oils or for medicinal purposes. In addition, many oils can be used as functional food.

A comparative Study of Structural Properties and Antacid activity of some commercial samples of Shauktika bhasma

Backgroud: Shauktika Bhasma is a traditional ayurvedic medicine which is an excellent remedy for a number of stomach disorders, hyper acidity and ulcers. It is prepared from mother pearl by subjecting the powder of mother pearl to traditional ayurvedic processes. To get a worldwide recognition to such supreme ancient medicine, it is necessary to reinvestigate it on the basis of modern analytical techniques.In the present work a comparative study of some commercial samples of Shauktika bhasma is undertaken to understand the current status of this bhasma and to explore its acid neutralization capacity using back titration method. Materials and Methods: Samples from renowned pharmacies are collected and subjected to chemical and structural investigations using analytical techniques like XRD, IR and UV. Back titration method is applied to find acid neutralizing capacity of these bhasma samples. Conclusion:The study reveals that Shauktika bhasma is chemically calcite form of calcium carbonate. Antacid activity of the samples is reported for these samples using simple titration method which is useful to estimate number of moles neutralized for a quick comparison. The antacid activity of the samples is found to be inversely proportional to the crystallite size of the bhasma.

Mode of Action of Trikatu Ghrita Yukt Swarnabhasma in Pandu Roga (Anaemia)

Pandu roga, an ancient Ayurvedic term used to describe a specific disease, has been recognized and discussed by various Ayurvedic scholars. According to their teachings, Pandu roga is considered a type of Rasa pradoshaj vikara, with Pitta dosha playing a prominent role in its manifestation. The key characteristic of this disease is Panduthwa, or Pallor, which exhibits clinical features similar to modern-day Anaemia .A condition in modern medicine, involves a deficiency in red blood cells or hemoglobin percentage due to decreased production. It is often associated with poor nutrition and overall health. The problem is commonly observed in low birth weight infants, overweight children who lack energy for physical activity, school-going children, adolescents, and pregnant women. In traditional Ayurvedic medicine, there are various formulations suggested for managing Anaemia, one of which is Trikatu Ghrita Yukt Swarnabhasma. This herbal preparation contains Trikatu, a combination of three spices - Shunthi (Zingiber officinale), Marich (Piper nigrum), and Pippali (Piper longum). These spices are renowned for their digestive and metabolic properties. Additionally, Swarnabhasma, derived from gold, has been utilized in Ayurveda for its rejuvenating and tonic effect.

Critical review of the utilization of Panchagavya in the form of Nutraceuticals

Background: In India Cow represents Mother Earth and is commonly called as ‘Gaumata’ because of its nourishing nature. In Ayurveda, since ancient time’s cow products have been used for a healthy body, therapeutic purposes and pharmaceutical processes. Panchagavya is a mixture prepared by using five ingredients derived from Cow. The three direct ingredients are cow dung, cow urine and cow milk and the two derived products are ghee and curd each of which represents ‘Gavya’ i.e., obtained from Gou (Cow). Each Gavya can be used individually or in combination with other products. Any product generated from food sources having additional health advantages in addition to the essential nutritional content contained in foods is considered as a Nutraceutical. The long standing consumer acceptability of nutraceuticals is brought about by their association with conventional medicine. Although the idea of nutraceuticals has grown in popularity recently, it has its roots in the traditional Ayurvedic medicine of ancient India. Aims and Objectives: This work is a modest attempt to employ Panchagavya as a kind of nutraceutical. Materials and Methods: Various books and review articles were referred to carry out this review. Results and Conclusion: A number of illness, including obesity, dietary and gastrointestinal tract abnormalities, leucoderma, wound healing, leucorrhoea, hepatitis, TB, ulcer, chemical intoxication, as well as other bacterial, fungal and viral infections, are advised for Panchgavya therapy. Nutraceuticals are substances that have physiological benefits or provide protection against chronic diseases. Using this concept, Panchgavya can be used as a kind of nutraceutical.