Awareness Of Healthcare Professionals Research Articles

6301352 Thromboelastography (TEG) in Major Obstetric Haemorrhage: Assessment of Use during Major Haemorrhage and Healthcare Professional Awareness of TEG

6301352 Thromboelastography (TEG) in Major Obstetric Haemorrhage: Assessment of Use during Major Haemorrhage and Healthcare Professional Awareness of TEG

Gonorrhoea in Poland in 2021.

The incidence of gonorrhoea at the European level increased over 2012-2019, decreased in 2020, and then reached higher values in 2021 than in 2019. Analysis in the descriptive epidemiology scheme of gonorrhoea notification in surveillance in Poland in 2021 (being the second year of the COVID-19 pandemic). Case-base data from surveillance of gonorrhoea were used: confirmed case (meeting laboratory criteria), probable (meeting clinical criteria and contact with confirmed case) and possible (only in Poland - physician diagnosed gonorrhoea, no information available for proper classification). Statistic Poland data was used to calculate the indicators. Data on patients treated in dermatology-venereology clinics between 2019-2021 were taken from the Bulletins of the Ministry of Health. The incidence of gonorrhoea in Poland in 2021 was only a fraction of recorded in the EU/EEA (0.74 vs. 13.7/100000)-similar to the first pandemic year and were about half of those notified in the 2019 (the peak year; 281 vs. 522 cases). There were 15.5 men per one female (incidence: 1.6/100000 men, 0.1/100000 women). Every second case was among aged 25-34 (49.62%), every fourth-aged 35-44 (23.11%). Under 15, no cases were reported. The predominant site was the genitourinary (excluding missing data: 85.3%). The cases with missing information on transmision increased (49.1%; aged 45+: 72.0%, women: 76.5%). Delays in reporting data were identified (greater than in 2019, however, less than in 2020), ~17% cases were from 2019-2020. Dermatology-venerology clinics treated 385 people - less than in 2020, however, more than reported in epidemiological surveillance (vs. 281). The COVID-19 pandemic has influenced on the surveillance system in Poland. There are difficulties in interpreting the epidemiological trend. It is necessary to: 1) intensify systemic solutions in the area of prevention, including sexual partners; 2) raise the awareness of healthcare professionals and sanitary inspection workers on the role of collecting epidemiological information.

A Longitudinal Analysis of Black Box Warnings: Trends and Implications for Drug Safety.

A black box warning, signaling potential life-threatening adverse effects of medications or medical devices, is crucial for public and healthcare professional awareness. Comprehending and adhering to these warnings can prevent serious harm. This review aims to elucidate their significance. Data on drugs with black box warnings were collected from the Food and Drug Administration's (FDA's) official website using the search term 'Boxed warnings' from January 1, 2015, to January 31, 2024. A MicrosoftExcel spreadsheet (Microsoft Corporation, Redmond, WA, USA) containing black box warnings for this period was downloaded from the FDA's website. Additional parameters, such as drug class and whether the warnings were new or existing, were added to the downloaded spreadsheet. The collected data were organized by year, categorizing new and existing warnings, along with details on the evidence source, system-wise classification, and black box warnings for commonly used drugs, including their clinical significance. Results show that in the past decade, 40% of black box warnings were issued in 2023, followed by 12% in 2022. Most warnings (67%) comprised existing ones with minor revisionswhile 29% were new. Nine existing warnings were removed during the period. Post-marketing studies predominantly provided evidence for these warnings. Neuropsychiatric concerns like addiction potential (31%), suicidal tendency (7%), and hypersensitivity reactions (12%) were the frequently encountered black box warnings. Black box warnings play a crucial role in highlighting the serious adverse effects of medications. Neuropsychiatric warnings have been frequent over the past decade. Awareness of these warnings is essential to prevent adverse effects and enhance patient care, especially concerning drugs like guaifenesin/hydrocodone bitartrate, zolpidem, and montelukast commonly encountered in clinical practice.

Facilitators and barriers of implementing end-of-life care volunteering in a hospital in five European countries: the iLIVE study

BackgroundEnd-of-life (EoL) care volunteers in hospitals are a novel approach to support patients and their close ones. The iLIVE Volunteer Study supported hospital volunteer coordinators from five European countries to design and implement an EoL care volunteer service on general wards in their hospitals. This study aimed to identify and explore barriers and facilitators to the implementation of EoL care volunteer services in the five hospitals.MethodsVolunteer coordinators (VCs) from the Netherlands (NL), Norway (NO), Slovenia (SI), Spain (ES) and United Kingdom (UK) participated in a focus group interview and subsequent in-depth one-to-one interviews. A theory-inspired framework based on the five domains of the Consolidated Framework for Implementation Research (CFIR) was used for data collection and analysis. Results from the focus group were depicted in radar charts per hospital.ResultsBarriers across all hospitals were the COVID-19 pandemic delaying the implementation process, and the lack of recognition of the added value of EoL care volunteers by hospital staff. Site-specific barriers were struggles with promoting the service in a highly structured setting with many stakeholders (NL), negative views among nurses on hospital volunteering (NL, NO), a lack of support from healthcare professionals and the management (SI, ES), and uncertainty about their role in implementation among VCs (ES). Site-specific facilitators were training of volunteers (NO, SI, NL), involving volunteers in promoting the service (NO), and education and awareness for healthcare professionals about the role and boundaries of volunteers (UK).ConclusionEstablishing a comprehensive EoL care volunteer service for patients in non-specialist palliative care wards involves multiple considerations including training, creating awareness and ensuring management support. Implementation requires involvement of stakeholders in a way that enables medical EoL care and volunteering to co-exist. Further research is needed to explore how trust and equal partnerships between volunteers and professional staff can be built and sustained.Trial registrationNCT04678310. Registered 21/12/2020.

Evaluation of functional gastrointestinal disorders in children aged 4-10 years with autism spectrum disorder.

Gastrointestinal system disorders are known to be prevalent among children with autism spectrum disorder (ASD). Some ASD-associated comorbidities are abdominal pain, constipation, diarrhea, gastroesophageal reflux, sleep disturbances, epilepsy, and psychiatric problems. Nonetheless, there is still limited information about the presence of functional GI disorders (FGIDs) among children with ASD, especially in Türkiye. Using the Rome criteria, we aimed to investigate FGIDs in children with ASD. The sample of the study consisted of 68 children aged 4-10 years, diagnosed with ASD according to the DSM-5 diagnostic criteria and had scores greater than 30 on the Childhood Autism Rating Scale (CARS-2) and an age-sex matched control group (n=78). The Rome III criteria were used to evaluate FGIDs. The frequency of FGIDs in the ASD group was higher (76.5%) compared to the control group (p < 0.001). Compared to the control group, abdominal migraine frequency increased 10 times (p=0.012), functional constipation 7 times (p < 0.001), and fecal incontinence 6 times (p < 0.001) in the ASD group. Stool retention was not present in most children in the ASD group who were found to have fecal incontinence. In this study, the most common FGIDs in the ASD group were abdominal migraine, functional constipation, and non-retentive fecal incontinence. The finding that most children with ASD who had fecal incontinence did not show stool retention implicated social, psychological, and behavioral factors as the causes of incontinence. Raising awareness of healthcare professionals about the frequency of FGIDs in children with ASD will improve many areas in the daily lives of these children.

Study to evaluate awareness about medication errors and impact of an educational intervention among healthcare personnel in a cancer hospital.

Medication errors (MEs) are preventable incidents that can result in harm to patients. Therefore, it is essential for healthcare professionals (HCPs) to be well-informed about MEs. This study aims to assess the awareness levels of HCPs and the impact of educational intervention on their understanding of MEs. Responses to a 17-question structured, self-administered questionnaire assessing the awareness of HCPs regarding fundamental aspects of MEs, ME reporting systems, and their ability to make recommendations for improving the system for handling the MEs were collected both before and after two weeks of educational intervention administration. Of a total of 114 HCPs who initially participated in the study, six dropped following the intervention. The awareness regarding the Class A questionnaire was good in most physicians (60%), nurses (60%), and pharmacists (57%) before the intervention, which improved postintervention, with physicians (80%), nurses (32%), and pharmacists (78%) demonstrating excellent awareness. The awareness level in the Class B questionnaire was also improved to excellent in most physicians (70%), pharmacists (85%), and nurses (85%) following the intervention, while it was excellent only in 50%, 35%, and 1% of physicians, pharmacists, and nurses, respectively, preintervention. In the Class C questionnaire, most physicians (40%) and nurses (60%) had good awareness, while pharmacists (35%) demonstrated excellent awareness preintervention. Postintervention, most physicians (70%), nurses (77%), and pharmacists (64%) exhibited excellent awareness. Most oncology practice HCPs demonstrate a good to average level of awareness regarding MEs. Clinical pharmacists' educational interventions can significantly enhance awareness among HCPs concerning MEs.

The vicious circle mechanism in atopic dermatitis: psychological distress as cause and effect of atopic dermatitis

Introduction and purpose: Atopic dermatitis (AD) is chronic inflammatory skin disorder. It typically begins in infancy or childhood and might persist into adulthood. AD is characterized by dry, itchy, eczematous skin. The lesions can vary in intensification from mild to severe according to patient age or body region. AD requires ongoing management to control the symptoms. Skin manifestations along with the demand of treatment and care regimens significantly impact quality of life (QOL) in patients with AD. Individuals suffering from this condition are more prone to developing mental health disorders, which are often linked to emotional stress they experience. Exposure to stress exacerbates AD and stimulates skin changes, which in turn leads to intensification of treatment regimens. This cause-and-effect chain can be considered as a vicious circle mechanism. The aim of the review is to highlight the phenomenon by examining current literature on this topic in order to raise the awareness of healthcare professionals regarding this subject as well as implement appropriate and complete support for patients struggling with AD. A brief description of the state of knowledge: The pathophysiology of AD is multifactorial. Numerous studies explore the impact of stress on the deterioration of AD symptoms and delve into its pathogenic concepts. Simultaneously, researchers highlight increased psychological distress in AD patients, which surpass that observed in many other chronic conditions. Summary: Psychological factors play a significant role in AD. It demands considering mental health screening and support as a part of clinical practice, treating AD patients. Further research is necessary to provide efficient and comprehensive interventions.

Evaluation and risk communication of the effects of alcohol exposure on disposable procedure masks and portable air purifiers in hospital environments.

Electret technology was widely used to prevent the airborne transmission of bioaerosols during the COVID-19 pandemic and improve the filtration efficiency of masks and high-efficiency particulate air (HEPA) filters. As alcohol disinfectants are widely used in medical and welfare institutions, concerns about alcohol exposure inactivating electret exist. However, comprehensive alcohol exposure tests have not been conducted on masks and HEPA filters distributed in Japan. Twenty-five types of masks and five types of HEPA filters were subjected to a discharging process according to ISO 16890 to quantitatively elucidate the resistance to alcohol exposure. Measurements of changes in filtration efficiency and pressure drop before and after discharge show that 17 masks (68%) and four HEPA filters (80%) exhibited a significant decrease in filtration efficiency, confirming their vulnerability to alcohol. In addition, a survey (n = 500 Japanese adults, including 30 healthcare professionals) revealed that ∼90% of the general public were unaware that alcohol exposure could degrade masks and air purifiers. Furthermore, 36% of the surveyed healthcare professionals had sprayed alcohol directly onto their masks. The effectiveness of user warnings through product labels and instructions was investigated from the perspective of ensuring the safety of patients and healthcare professionals. Results revealed that the best approach was to describe the extent and duration of the adverse effects caused by disregarding precautions. Increase in awareness of healthcare professionals and general public by authorities and manufacturers through guidelines and warning labels would reduce the risk of inhaling bioaerosols caused by unintentional electret inactivation.

Maximizing Professional-Led Sexual Well-being Support in Cancer Care: Findings From a Qualitative Process Evaluation Following Healthcare Professionals' Engagement With an eLearning Resource.

Provision of healthcare professional (HP)-led sexual support in cancer care is lacking, perpetuated by barriers including a lack of HP awareness of sexual concerns and strategies to help patients and partners cope. In response, the Maximizing Sexual Wellbeing|Cancer Care eLearning resource (MSW|CC) was developed and demonstrated efficacy in reducing HPs' attitudinal barriers to the provision of sexual support. However, the mechanisms for such change are not yet known. A qualitative process evaluation was used to explore mechanisms that influence HP engagement with MSW|CC and its adoption into practice. Semistructured interviews were conducted with HPs providing cancer care in Northern Ireland upon MSW|CC completion. Interviews were audio-recorded, transcribed verbatim, and thematically analyzed. Seventeen participants were interviewed, and 4 key themes were identified: (1) MSW|CC raises HPs' awareness of the need for holistic sexual support as part of routine clinical care; (2) MSW|CC prepares and equips HPs to provide sexual support in cancer care; (3) MSW|CC is coherent, engaging, and acceptable; and (4) MSW|CC: moving forward. Participants derived benefits from MSW|CC, deeming it an acceptable resource. Insights into MSW|CC mechanisms of success were identified, including language to address sexual concerns, alongside patient referral resources. Perceived MSW|CC shortcomings from an earlier study were confirmed as a software issue.Implications for Practice:Healthcare professionals require training and resources to enhance sexual support provision in cancer care. Proactive implementation strategies used to maximize HP engagement with MSW|CC could equip HPs with tools to improve patient sexual outcomes after cancer.

Lessons learned from a cluster of immunization errors in newborns.

Vaccines are safe and effective, but adverse reactions can occur. Immunization errors (IEs) are one of the types of adverse events following immunization. The Moroccan Pharmacovigilance Centre (MPC) received a cluster of IEs from a maternity university hospital (MUH) regarding six newborns who were inadvertently administered rocuronium instead of hepatitis B (HepB) vaccine. The newborns experienced respiratory distress and one had a fatal outcome. The study aimed to describe the investigation findings, the underlying causes, and contributing factors of the IEs cluster, and proposed risk minimization actions. We carried out a descriptive analysis of the cluster of IEs related to the HepB vaccine reported to the MPC. An investigation was conducted by the Ministry of Health according to the World Health Organization guidance. The root cause analysis was performed to identify underlying causes and contributing factors that lead to IE occurrence. The cluster analysis showed that the main contributing factors were the look-alike rocuronium and HepB vaccine packaging, the first-time running HepB vaccination for newborns in the MUH, the lack of a full-time pharmacist, and the unsafe storage of rocuronium and vaccines. The administration of Sugammadex to the newborns followed by their transfer to the neonatal care unit resulted in the recovery of five of the six newborns. Proposed recommendations included (1) raising awareness of healthcare professionals to the risk related to look-alike medications, (2) training nurses to ensure vaccination to implement procedures related to immunization practices, (3) nomination of a full-time pharmacist, (4) reassessment of the safety of drug storage and dispensing at the hospital pharmacy, particularly for high-alert medications. Reporting IEs, particularly serious ones, allows us to identify causes and contributing factors that led to their occurrence. Lessons learned from errors are key to take risk minimization actions to improve vaccine safety worldwide.

Healthcare Professionals' Knowledge, Attitude and Perception toward Adverse Drug Reaction Reporting in Saudi Arabia: A Systematic Review

Aims: To systematically evaluate the currently available evidences about the knowledge, attitude and perceptions of healthcare professionals in Saudi Arabia towards reporting adverse drug reactions to the Saudi Food and Drug Authority (Saudi FDA) as the regulatory authority monitoring adverse drug reactions in the country. &#x0D; Study Design: Systematic Review.&#x0D; Methodology: A systematic search of the literature was conducted on ScienceDirect, PubMed, OVID databases as well as Google Scholar for all studies published in English up to June 2023. Strengthening the Reporting of Observational Studies in Epidemiology Joanna Briggs Institute (STROBE) checklist was used to appraise the quality of the cross-sectional studies included in this review.&#x0D; Results: A total of 27 studies conducted in different healthcare institutions in Saudi Arabia were included in the systematic review. Overall, in the knowledge domain, the awareness of healthcare professionals toward the existence of a national pharmacovigilance adverse drug reaction reporting system ranged from 10% to 95%. In the attitude domain, the belief of the healthcare professionals that reporting adverse drug reaction is a professional obligation ranged from 12.80% to 90.20%. In the perception domain, 46.53% to 100% of healthcare professionals perceive adverse drug reaction reporting has a positive impact on healthcare system and improves patient’s care and quality of life.&#x0D; Conclusion: Despite having positive attitude toward reporting adverse drug reaction, the healthcare professionals require more education and training in utilizing the Saudi FDA provided adverse drug reaction form and online system to report on the adverse drug reaction that they encounter during their practice.

Analysis of the awareness by healthcare professionals and the public about viral hepatitis in the context of decentralisation of diagnostics

Viral hepatitis B and C (VH) is a global public health problem. The peculiarity of VH is usually asymptomatic onset of the disease, so early diagnosis and, accordingly, treatment of the disease at early stages will help to reduce mortality and costs associated with treatment of complications.&#x0D; The aim of our study was to investigate the level of awareness of health care professionals (HCPs) and the general population about VH, as well as their attitudes toward VH testing.&#x0D; In accordance with the objective, a survey form for healthcare professionals and a survey form for the general population were developed. Methods of comparative, statistical, graphical and logical analysis were used to process the survey results, describe them and draw conclusions.&#x0D; 79% of surveyed healthcare professionals believe that the problem of VH spread is relevant for Ukrainian society, 37% consider VH a very dangerous disease. 63% of respondents know the differences in treatment, but 60% answered incorrectly about the possibility of complete cure of HCV. The main obstacle to diagnosing VH is the belief that people do not belong to the risk group (82.3%), but only 23.3% of the surveyed population will not be diagnosed for this reason. Due to the cost of the procedure, 13.8% of the population will refuse to be tested. 71% of respondents said they knew the main symptoms of VH, while 84% did not consider themselves to be at risk of infection. In case of absence of symptoms, 55% of respondents are not ready to buy a test in a pharmacy for self-diagnosis of VH at their own expense. 89% of respondents are ready to buy a test for self-diagnosis in a pharmacy if they suspect VH. In general, the results of the study emphasize the relevance of decentralization of VH diagnostic services.&#x0D; The majority of respondents, both among the general population and healthcare professionals, are aware of the ways of VH infection, but do not consider it necessary to be tested. In our opinion, there is an urgent need for an information campaign focused on the need for annual VH diagnosis. In the future, decentralization of testing and information campaigns in cooperation with pharmacists will help reduce the burden on the economic system of providing testing and treatment for people with VH at the expense of the state.

The association of resilience with self-care and quality of life in people with chronic obstructive pulmonary disease: A cross-sectional study.

To investigate the association of resilience with self-care and quality of life in people with chronic obstructive pulmonary disease. Cross-sectional study. Data were collected between February and May 2021. Self-care was measured with the self-care of chronic illness inventory, quality of life was measured with the clinical chronic obstructive pulmonary disease questionnaire and resilience was measured with the resilience evaluation scale. Possible confounders were included (sex, age, smoking, time since diagnosis of chronic obstructive pulmonary disease, educational level, social support and pulmonary function). Multiple regression analysis was performed among the determinants, confounders and both outcomes. Participants scored fairly well on resilience (mean 22.5). Self-care scored reasonably well (mean maintenance 65.9, mean monitoring 70.9, mean management 59.9 and mean confidence 71.5). Quality of life scored mediocre (mean 2.6). The results of the linear multiple regression were resilience, which is associated with self-care confidence and quality of life when adjusted for possible confounders. This means people with chronic obstructive pulmonary disease with higher resilience have better self-care confidence and higher quality of life. The outcome contributes to strengthening nursing care and further developing nurses' knowledge. The results can contribute to increasing awareness for healthcare professionals that resilience can potentially increase self-care and quality of life.

SAĞLIK ÇALIŞANLARININ STRATEJİK PLANLAMA FARKINDALIĞININ İNCELENMESİ

Strategic planning is a process in which all employees are mobilized to achieve the hospital's vision, goals, and bjectives and critical success indicators. The implementation of an effective strategic planning process depends on the awareness of the health professionals, who play an important role in the delivery of health services, as well as the hospital management. For this reason, it is essential for management sciences to understand which variables affect the strategic planning awareness of healthcare professionals. With this background, the aim of the research is to examine the strategic planning awareness of health workers in terms of various variables. The research is a cross-sectional and descriptive study. Data were collected by face-to-face survey method on 450 healthcare professionals working in private hospitals operating in Istanbul (Turkey). To test the construct validity of the scale, confirmatory factor analysis using the Amos program and explanatory factor analysis using the SPSS program were applied. It was determined that the strategic planning awareness of the senior management is higher than those who do not have administrative duties. In addition, it was found in the study that there was no significant difference in the strategic planning awareness of clinical unit employees and administrative unit employees. Strategic planning acts as a guide in shaping the future of hospitals. Health professionals, on the other hand, are in a position to undertake the most critical task in carrying hospitals to this future. For this reason, it is necessary to increase the strategic planning awareness of healthcare professionals by the hospital management.

Factors Affecting Attitudes Towards Cancer, Cancer Prevention, and Early Diagnosis Behaviors Among Cancer Patient Relatives.

Attitudes towards cancer may affect the cancer prevention behaviors of cancer patients' relatives and their participation in cancer screening. Knowing the factors affecting attitudes will shed light on the education programs to be planned to encourage individuals to gain a positive attitude towards cancer and positive health behaviors in cancer prevention. Determining the behaviors towards cancer prevention and cancer screening, identifying reasons that prevent participation in cancer screening, determining the factors associated with the attitudes of cancer patients' relatives towards cancer, determining the factors affecting their attitudes towards cancer of cancer patients' relatives, can increase the awareness of healthcare professionals and patient relatives on the subject. The aim of the present study was to determine cancer prevention and early diagnosis behavior and the factors affecting the attitudes of towards cancer of cancer patient relatives. The descriptive and analytical study was completed with 321 relatives of cancer patients. The data were collected by the face-to-face interview method. The interview was conducted in a quiet place, alone with the participant, using a clear and simple language, allowing people to speak freely, and avoiding criticism and evaluation. About half of the participants smoked (49.5%), many did not do regular physical activity (67.3%) or protect themselves from the sun (77.3%), and only 10.9% had regular screening tests. The reasons for not having a screening test were ignorance, disregard, lack of complaints, and fear. Acording to binary logistic regression analysis, the determinants included factors of negative attitudes toward cancer with the age of the patient (Exp(β): 1.024), low education level (Exp(β): 2.572), being the child (Exp(β): 8.484) or sibling (Exp(β): 8.801) of the patient, not being protected from the sun (Exp(β): 2.063), and not doing physical activity (Exp(β): 1.744). Even for those having positive health behaviors, such as not smoking (Exp(β): 2.008) and using sun protection (Exp(β): 2.280), the attitudes towards cancer were negative for the Impossible to Recover sub-dimension. Cancer prevention behaviors and regular participation in cancer screening of cancer patients' relatives were very low. It was determined that low education level, increasing age of the patient, and the degree of relation to the patient negatively affected attitudes towards cancer, and that there was a need for education. We believe that the results of the present study will contribute to evidence-based practice for cancer prevention and early diagnosis.

The mediating role of strategic planning awareness in the impact of organizational innovation on business excellence in hospitals

PurposeEvaluating the operational outcomes of hospitals is critical concerns for hospital managers. The realization of these evaluations through the principles of Total Quality Management (TQM) is important so that decision-makers can base their decisions on rational grounds. To achieve TQM principles, hospitals need innovative processes that can adapt to changing patient expectations. Innovation activities that will lead to business excellence can be achieved with the strategic planning awareness of healthcare professionals. In this study, it is aimed to evaluate the effect of organizational innovation on business excellence and to reveal the role of strategic planning awareness in this relationship in hospitals.Design/methodology/approachThe data were collected using a quantitative questionnaire to 450 healthcare professionals working in private hospitals operating in Istanbul (Turkey). The data were analyzed using the AMOS (Analysis of Moment Structures) 23.0 and SPSS (Statistical Package for the Social Sciences) for Windows 25.0 program. In addition to the reliability analysis, confirmatory factor analysis was performed using the AMOS program to test the construct validity of the scales. The model established in line with the research hypotheses was tested with path analysis and mediator role analysis.FindingsThe results confirm that organizational innovation has a statistically significant and positive effect on strategic planning awareness and business excellence. In addition, it has been determined that strategic planning awareness has a statistically significant and positive effect on business excellence. Moreover, the research model confirms that strategic planning awareness plays a mediating role in the relationship between organizational innovation and business excellence.Research limitations/implicationsThe limitation of the study is that it was conducted only in private hospitals. A comparative study that includes the public health sector can further strengthen the research framework.Practical implicationsHospitals that invest in innovative activities can get the reward of their efforts as business excellence. However, this is affected by the strategic planning awareness of healthcare professionals. Research results present the role of strategic planning awareness on the way to business excellence led by organizational innovation. Achieving business excellence in complex and constantly changing environmental conditions depends on an appropriate strategic plan for hospitals. In order to achieve these goals included in the strategic plans, the education of healthcare professionals that contributes to their strategic perspectives should be supported and their participation in decision-making processes should be ensured.Originality/valueThe research contributes to the literature on the relationship between organizational innovation and business excellence in the health sector. In addition, revealing the role of strategic planning awareness of healthcare professionals in this relationship is the originality of the research. In addition, the research supports the literature that allows performance evaluation in hospitals to be carried out with a business excellence model based on TQM.

Awareness of healthcare professionals about risk minimization measures associated with COVID-19 vaccines: international cross-sectional study

The Coronavirus 2019 (COVID-19) pandemic caused the global healthcare to face one of the most significant challenges since the World Health Organization was founded over 70 years ago. The development and approval of marketing authorization for vaccines with the COVID-19 indication represents an opportunity to address this public health threat. The aim of this study is to analyze the awareness of healthcare professionals (HCPs) on the benefit-risk balance, safety, and risk minimization measures associated with vaccine administration. This is an open-label, prospective, 1-year cross-sectional study (2021–2022). It was conducted using the indirect anonymous survey method by completing an online and paper questionnaire containing open and close-ended questions. The results obtained locally and internationally were validated, systematized, compared, and analyzed. The study included 344 HCPs from 40 countries on six continents. The data show that among HCPs, the highest proportion are pharmacists and doctors in the age group of 21–30 years. А 20% difference in results was observed regarding the statement that vaccines approved for use are of high quality, efficacious, and safe, 68% (on local level) and 88% (on global level) of the respondents agreeing. On the other hand, ∼80% of HCPs both in Bulgaria and abroad felt that they need additional professional data for the vaccines authorized for use. Surveys assessing the awareness and attitudes of HCPs regarding risk management and adverse reactions are key to increasing the level of informed decision-making and can help fighting the world infodemic with data from trusted sources.

Advantages and disadvantages of connected insulin pens in diabetes management.

Insulin administration remains vital to the treatment of diabetes and although there have been advances in insulin delivery, evidence suggests that many people with diabetes on insulin therapy have suboptimal glycemic management. Recent advancements in insulin administration techniques include connected insulin devices, such as connected insulin pens and pen caps. In this review, we provide an overview of the literature on the use of connected insulin pens and pen caps to further elucidate the clinical benefits and drawbacks of these devices. We discuss the development of these devices, outlining the characteristics of insulin pens and pen caps with regulatory approvals. These devices have different features that can ease the burden of diabetes management, including automatic recording of insulin dose information, tracking of insulin-on-board, bolus calculators, and missed dose alerts. Despite the advantages of connected pens and pen caps, a small percentage of insulin users are currently using these devices, due to many factors, including lack of health-care professional awareness, initial training for prescribers, and setup of the device. Overcoming these barriers and publishing more data demonstrating the glycemic outcomes associated with these systems could improve diabetes management for people living with diabetes. As health-care systems become increasingly digital, connected insulin pens have the potential to allow a data-driven approach to diabetes management for people who are not interested in, cannot afford, or do not have intensive insulin regimens that might warrant use of insulin pumps or automated insulin delivery systems.

The Role of Real-World Evidence in Treatment Decision-Making, Regulatory Assessment, and Understanding the Perspectives of People with Type2 Diabetes: Examples with Gliclazide MR.

Real-world evidence (RWE) plays an important role in the management of type2 diabetes (T2D). It provides data about the effectiveness and safety of an intervention from outside the randomised controlled trial (RCT) setting and allows healthcare professionals (HCPs) to determine if RCT data are applicable to their patients in routine clinical practice. This review provides a discussion of the value of RWE in T2D management in day-to-day clinical practice, with a focus on RWE with sulfonylureas (SUs), and presents two examples of a new generation of international real-world studies in people with T2D managed in routine clinical practice. RWE plays a valuable role in advising HCPs in the day-to-day management of T2D, informing regulatory authorities with regard to pharmacovigilance and post-approval updates, and providing insights with regard to patients' treatment adherence and preference. RWE should be used alongside RCTs to increase HCP awareness and understanding of their patients' perspectives, potentially allowing for improvements in treatment adherence, glycaemic control and health-related quality of life (HRQoL). In addition, real-world studies must be conducted in a way that generates robust RWE by limiting the risks of bias and confounding as much as possible. A growing body of RWE is emerging from Asia. For example, in a preliminary HRQoL analysis of the Joint Asia Diabetes Evaluation (JADE) Register, Asian people with T2D had better HRQoL with gliclazide-based treatment than with other SU agents, despite being older and having more diabetes-related complications.

Vibrio cholerae-An emerging pathogen in Austrian bathing waters?

Vibrio cholerae, an important human pathogen, is naturally occurring in specific aquatic ecosystems. With very few exceptions, only the cholera-toxigenic strains belonging to the serogroups O1 and O139 are responsible for severe cholera outbreaks with epidemic or pandemic potential. All other nontoxigenic, non-O1/non-O139 V.cholerae (NTVC) strains may cause various other diseases, such as mild to severe infections of the ears, of the gastrointestinal and urinary tracts as well as wound and bloodstream infections. Older, immunocompromised people and patients with specific preconditions have an elevated risk. In recent years, worldwide reports demonstrated that NTVC infections are on the rise, caused amongst others by elevated water temperatures due to global warming.The aim of this review is to summarize the knowledge gained during the past two decades on V.cholerae infections and its occurrence in bathing waters in Austria, with aspecial focus on the lake Neusiedler See. We investigated whether NTVC infections have increased and which specific environmental conditions favor the occurrence of NTVC. We present an overview of state of the art methods that are currently available for clinical and environmental diagnostics. Apreliminary public health risk assessment concerning NTVC infections related to the Neusiedler See was established. In order to raise awareness of healthcare professionals for NTVC infections, typical symptoms, possible treatment options and the antibiotic resistance status of Austrian NTVC isolates are discussed.