Aversive Arousal Research Articles

13. Increases in Aversive Arousal Promote Increased Craving and Greater Aversive Pruning During Planning in Amphetamine Use Disorders: An Experimental Computational Modelling Study

13. Increases in Aversive Arousal Promote Increased Craving and Greater Aversive Pruning During Planning in Amphetamine Use Disorders: An Experimental Computational Modelling Study

Water Drinking Behavior Associated with Aversive Arousal in Rats: An Integrative Approach.

Cholinergic muscarinic stimulation of vast areas of the limbic brain induced a well-documented polydipsia in laboratory rats. This excessive water-drinking behavior has not received any convincing biological and physiological interpretation for the last 50 years. This review offers such an interpretation and suggests that cholinergically induced drinking response, mostly by carbachol, is associated with activation of the ascending mesolimbic cholinergic system that serves for initiation of emotional aversive arousal of the organism. The ascending cholinergic system originates from the laterodorsal tegmental nucleus, has a diffuse nature, and affects numerous subcortical limbic structures. It is proposed that the carbachol-induced drinking response is related to the state of anxiety and does not serve the regulation of thirst. Instead, the response is anxiety-induced polydipsia that might occur as a soothing procedure that decreases the aversiveness of the negative emotional state induced by carbachol. It is concluded that carbachol-induced water-drinking behavior is a rewarding process that contributes to alleviating the feeling of anxiety by bringing some relief from the cholinergically induced aversive state, and it is a homologue to anxiety-driven polydipsia in humans.

The administration of the opioid buprenorphine decreases motivational error signals

While opioid addiction has reached pandemic proportions, we still lack a good understanding of how the administration of opioids interacts with cognitive functions. Error processing – the ability to detect erroneous actions and correct one’s behaviour afterwards - is one such cognitive function that might be susceptible to opioidergic influences. Errors are hypothesised to induce aversive negative arousal, while opioids have been suggested to reduce aversive arousal induced by unpleasant and stressful stimuli. Thus, this study investigated whether the acute administration of an opioid would affect error processing. In a double-blind between-subject study, 42 male volunteers were recruited and received either 0.2 mg buprenorphine (a partial µ-opioid receptor agonist and κ-opioid receptor antagonist) or a placebo pill before they performed a stimulus-response task provoking errors. Electroencephalograms (EEG) were recorded while participants performed the task. We observed no group differences in terms of reaction times, error rates, and affective state ratings during the task between buprenorphine and control participants. Additional measures of adaptive control, however, showed interfering effects of buprenorphine administration. On the neural level, decreased Pe (Error Positivity) amplitudes were found in buprenorphine compared to control participants following error commission. Further, frontal delta oscillations were decreased in the buprenorphine group after all responses. Our neural results jointly demonstrate a general reduction in error processing in those participants who received an opioid before task completion, thereby suggesting that opioids might have indeed the potential to dampen motivational error signals. Importantly, the effects of the opioid were evident in more elaborate error processing stages, thereby impacting on processes of conscious error appraisal and evidence accumulation.

Pupillometry and Hindsight Bias: Physiological Arousal Predicts Compensatory Behavior

According to violation–compensation models of cognitive conflict, experiences that violate expected associations evoke a common, biologically based syndrome of aversive arousal, which in turn motivates compensation efforts to relieve this arousal. However, while substantial research shows that people indeed respond with increased arousal to expectancy violating events, evidence for the motivating role of arousal is rarely found. In two within-subjects studies (N = 44 and N = 50), we demonstrate evidence for the motivating role of arousal in this violation–compensation process among university students. Using pupillometry and the hindsight bias phenomenon, we show that people respond with greater arousal when presented with expectancy violating information. In turn, we show that the pupillary response is positively related to the amount of hindsight bias being displayed. These findings provide further insights into the process underlying the hindsight bias and, crucially, support key predictions following from threat–compensation models.

Κίνητρα φιλοκοινωνικής συμπεριφοράς: Αγνός αλτρουισμός ή ψυχολογικός εξαναγκασμός;

Having as a starting point the dispute between the Empathy – Altruism Hypothesis and the Aversive Arousal Reduction Hypothesis, the present research focus on the study of the motives underlying prosocial behavior. Thus, an experimental process was designed in which male and female adults took part (N = 128). Participants first completed the Prosocial Tendencies Measure (PTM, Carlo & Randal, 2002) and the Toronto Empathy Questionnaire (TEQ, Spreng et al., 2009). Then, based on their answers, participants were assigned to eight groups and exposed to different experimental conditions (2 known – unknown x 2 in need of help – without need of help x 2 compel to receive help – absence of compel to receive help). Findings indicate that the level of empathy experiencing by the “benefactor” plays an important role in the performance of prosocial behavior. Nevertheless, the variable of familiarity with the person in need was found to be crucial in the performance of prosocial behavior as well as the need for help. Furthermore, findings suggest that the performance of prosocial behavior is a consequence of psychological pressure to the “benefactor” who, in turn, seems to use the performance of such a behavior as a means of psychological escape from a condition in which the request of help is salient.

Loss of control as a violation of expectations: Testing the predictions of a common inconsistency compensation approach in an inclusionary cyberball game.

Personal control relies on the expectation that events are contingent upon one’s own behavior. A common ‘inconsistency compensation approach’ posits that a violation of expectancies in social interaction triggers aversive arousal and compensatory effort. Following this approach, we tested the hypothesis that interventions affecting participants' decisions violate the expected personal control. In a modified version of the established cyberball paradigm, participants were not excluded, but consistently included. However, their decisions regarding the recipient of a ball throw in the virtual game were occasionally overruled (expectancy violation). We hypothesized that this intervention will trigger a P3 response in event-related brain potentials (ERP). Since this component is related to subjective expectancies, its amplitude was assumed to depend on the frequency of interventions (independent factor: loss of control). Further, we manipulated the vertical position of the participants’ avatar on the computer screen (independent factor: verticality). Building on research showing that verticality is related to the self-assigned power and influences the expected level of control, we hypothesized that the ERP effects of intervention should be more pronounced for participants with avatars in superior position. As predicted, both experimental factors interactively affected the expression of the ERP response: In case of low intervention frequency, P3 amplitudes were significantly pronounced if the participants’ avatar was positioned above as compared to below co-players (high > low self-assigned power). The effect of verticality could be traced back to a lack of adaptation of P3 amplitudes to recurring aversive events. By demonstrating that loss of control triggers ERP effects corresponding to those triggered by social exclusion, this study provides further evidence for a common cognitive mechanism in reactions to aversive events based on an inconsistency in expectancy states.

The role of the opioid system in decision making and cognitive control: A review

The opioid system regulates affective processing, including pain, pleasure, and reward. Restricting the role of this system to hedonic modulation may be an underestimation, however. Opioid receptors are distributed widely in the human brain, including the more “cognitive” regions in the frontal and parietal lobes. Nonhuman animal research points to opioid modulation of cognitive and decision-making processes. We review emerging evidence on whether acute opioid drug modulation in healthy humans can influence cognitive function, such as how we choose between actions of different values and how we control our behavior in the face of distracting information. Specifically, we review studies employing opioid agonists or antagonists together with experimental paradigms of reward-based decision making, impulsivity, executive functioning, attention, inhibition, and effort. Although this field is still in its infancy, the emerging picture suggests that the mu-opioid system can influence higher-level cognitive function via modulation of valuation, motivation, and control circuits dense in mu-opioid receptors, including orbitofrontal cortex, basal ganglia, amygdalae, anterior cingulate cortex, and prefrontal cortex. The framework that we put forward proposes that opioids influence decision making and cognitive control by increasing the subjective value of reward and reducing aversive arousal. We highlight potential mechanisms that might underlie the effects of mu-opioid signaling on decision making and cognitive control and provide directions for future research.

Thought-control difficulty motivates structure seeking.

Struggling to control one's mind can change how the world appears. In prior studies testing the compensatory control theory, reduced control over the external environment motivated the search for perceptual patterns and other forms of structured knowledge, even in remote domains. Going further, the current studies test whether difficulty controlling thoughts similarly predicts structure seeking. As hypothesized, thought-control difficulty positively predicted perceptions of causal connections between remote events (Study 1a) and nonexistent objects in visual noise (Study 1b). This effect was mediated by aversive arousal (Study 2) and caused specifically by thought-control difficulty as distinct from general difficulty (Study 3). Study 4 replicated the effect with a sample of meditators learning to control their thoughts, showing that thought-control difficulty was a powerful predictor of structure seeking. These findings reveal a novel form of motivated perception. (PsycINFO Database Record

More pain, more gain: Blocking the opioid system boosts adaptive cognitive control

The ability to adaptively increase cognitive control in response to cognitive challenges is crucial for goal-directed behavior. Recent findings suggest that aversive arousal triggers adaptive increases of control, but the neurochemical mechanisms underlying these effects remain unclear. Given the known contributions of the opioid system to hedonic states, we investigated whether blocking this system increases adaptive control modulations. To do so, we conducted a double-blind, placebo-controlled psychopharmacological study (n=52 females) involving a Stroop-like task. Specifically, we assessed the effect of naltrexone, an opioid blocker most selective to the mu-opioid system, on two measures of adaptive control that are thought to depend differentially on aversive arousal: post-error slowing and conflict adaptation. Consistent with our hypothesis, relative to placebo, naltrexone increased post-error slowing without influencing conflict adaptation. This finding not only supports the view that aversive arousal triggers adaptive control but also reveals a novel role for the opioid system in modulating such effects.

Startle potentiation to uncertain threat as a psychophysiological indicator of fear-based psychopathology: An examination across multiple internalizing disorders.

Heightened reactivity to uncertain threat (U-threat) is an important individual difference factor that may characterize fear-based internalizing psychopathologies (IPs) and distinguish them from distress/misery IPs. To date, however, the majority of existing research examining reactivity to U-threat has been within individuals with panic disorder and major depressive disorder (MDD) and no prior study has directly tested this hypothesis across multiple IPs. The current study therefore explored whether heightened reactivity to U-threat is a psychophysiological indicator of fear-based psychopathology across 5 groups: current (a) social anxiety disorder (SAD); (b) specific phobia (SP); (c) generalized anxiety disorder (GAD); (d) MDD; and (c) individuals with no history of psychopathology (controls). All 160 adults completed a well-validated threat-of-shock task designed to probe responses to predictable (P-) and U-threat. Startle eyeblink potentiation was recorded as an index of aversive arousal. Results indicated that individuals with SAD and SP evidenced greater startle potentiation to U-threat, but not P-threat, relative to individuals with GAD, MDD, and controls (who did not differ). The current findings, along with the prior panic disorder and MDD literature, suggest that heightened reactivity to U-threat is a psychophysiological indicator of fear-based disorders and could represent a neurobiological organizing principle for internalizing psychopathology. The findings also suggest that individuals with fear disorders generally display a hypersensitivity to uncertain aversive events, which could contribute to their psychopathology. (PsycINFO Database Record

Características de la respuesta emocional generada por las palabras: un estudio experimental desde la emoción y la motivación

Los estudios experimentales de la emoción y la motivación se han desarrollado de forma más frecuente con imágenes, sonidos y videos, sin embargo, son pocos los trabajos que han estudiado la respuesta emocional y motivacional ante las palabras, las cuales son estímulos que guían significativamente nuestra interacción social. Por lo anterior, el objetivo de la presente investigación fue identificar la capacidad que tienen las palabras para generar estados emocionales y las posibles diferencias entre hombres y mujeres. Para esto se llevó a cabo un estudio con 232 personas y se utilizaron 15 palabras con contenido afectivo, las cuales fueron evaluadas en las dimensiones de valencia, arousal y dominancia. Los resultados muestran que las palabras agradables, en especial aquellas con contenido sexual generan una valencia apetitiva, alto arousal y alta dominancia, y las palabras desagradables generan una valencia aversiva, bajo arousal y baja dominancia. Solo se encontraron diferencias significativas entre hombres y mujeres en la valencia de las palabras desagradables y el arousal de las palabras agradables

Legitimate vs. illegitimate restrictions - a motivational and physiological approach investigating reactance processes.

Threats to our freedom are part of our daily social interactions. They are accompanied by an aversive state of motivational arousal, called reactance, which leads people to strive to reestablish their threatened freedom. This is especially the case if the threat seems to be illegitimate in nature. However, reactance theory suggests that reactance should also be aroused when people are exposed to legitimate freedom threats. In this article we first aim to show that both illegitimate and legitimate freedom threats evoke reactance. Second, we aim to extend past work on reactance by exploring the underlying process of experiencing a legitimate vs. an illegitimate restriction. In the current study (N= 57) participants were restricted in an illegitimate (unexpected and inappropriate) or legitimate (unexpected but appropriate) way, or were not restricted at all. We assessed participants’ experience of reactance, their behavioral intentions to restore their freedom, their approach motivational states, as well as their physiological arousal (heart rate). Results indicated that when restricted in an illegitimate or a legitimate way, participants indicated the same amount of reactance as well as anger. However, when looking at people’s physiological reactions, important differences between illegitimate and legitimate restrictions become apparent. Illegitimate restrictions led to an immediate arousal, whereas legitimate restrictions led to a time delayed arousal. This suggests that illegitimate restrictions lead to a sudden increase in aversive arousal. Legitimate restrictions, however, seem to be associated with a more cognitive process in which people first need to structure their thoughts and reflect upon the situation before getting into the feeling of reactance in a physiologically arousing sense. Moreover a mediation analysis could show that behavioral intentions to regain one’s freedom result in positive and negative approach motivation. In sum we propose a combined dual-process and intertwined-process model explaining people’s reactions to legitimate vs. illegitimate restrictions.

Empathic concern drives costly altruism

Why do we self-sacrifice to help others in distress? Two competing theories have emerged, one suggesting that prosocial behavior is primarily motivated by feelings of empathic other-oriented concern, the other that we help mainly because we are egoistically focused on reducing our own discomfort. Here we explore the relationship between costly altruism and these two sub-processes of empathy, specifically drawing on the caregiving model to test the theory that trait empathic concern (e.g. general tendency to have sympathy for another) and trait personal distress (e.g. predisposition to experiencing aversive arousal states) may differentially drive altruistic behavior. We find that trait empathic concern – and not trait personal distress – motivates costly altruism, and this relationship is supported by activity in the ventral tegmental area, caudate and subgenual anterior cingulate, key regions for promoting social attachment and caregiving. Together, this data helps identify the behavioral and neural mechanisms motivating costly altruism, while demonstrating that individual differences in empathic concern-related brain responses can predict real prosocial choice.

Emotion as a necessary component of threat-induced death thought accessibility and defensive compensation

Terror management theory presents an account of how the avoidance of the potential anxiety accompanying knowledge of one’s inevitable mortality motivates a vast array of human behaviors. However, in practice, evidence from one of the hypotheses designed to test this account—the death thought accessibility (DTA) hypothesis—has been purely cognitive. The goal of the present research was to examine the role of emotion in this process. Participants were presented with existentially threatening stimuli under experimental situations in which the emotion induced by the threat (either aversive arousal or disgust) was present or absent. When the emotion was unaltered, participants exposed to threats, relative to controls, evinced high levels of DTA (Studies 1 and 3) and worldview defense (Study 2). When the emotion was misattributed to a neutral source (Studies 1–2) or down regulated via reappraisal (Study 3), however, DTA and worldview defense did not increase. The results and implications are discussed in relation to the threat compensation literature.

Appetitive and Defensive Arousal in Violent Video Games: Explaining Individual Differences in Attraction to and Effects of Video Games

Evidence surrounding the attraction to media violence is mixed and the effects of violent video game play on players varies across experimental participants. Differences in both may be explained by differences in experienced positive or negative arousal. This study utilizes the limited capacity model of motivated mediated message processing (LC4MP) and the motivation activation measure (MAM), which measures resting activation of the appetitive and aversive arousal systems, to explore the relationship between attraction to media violence, arousal, and aggression. In part 1, a questionnaire found that men and frequent players of violent games expected to enjoy violent games more than nonviolent games. In addition, participants whose scores on the MAM characterized them as risk takers (high scores on appetitive arousal and low scores on aversive arousal) indicated a stronger preference for violent games compared to the other three arousal types, which is in line with the LC4MP. In the experimental portion of the research, after playing a violent game, those participants characterized as risk avoidant (high on aversive arousal and low on appetitive arousal) were significantly less aggressive than all other arousal groups. Overall, results show that individual differences in the appetitive and aversive arousal systems can explain attraction to violent media. Furthermore, arousal resulting from violent video game play can be experienced as pleasant or aversive, and it is this experience of arousal that explains variations in aggressive responses to violent video games.

The Ascending Mesolimbic Cholinergic System—A Specific Division of the Reticular Activating System Involved in the Initiation of Negative Emotional States

The review summarizes evidences from extensive studies suggesting that ascending mesolimbic cholinergic system (AMCS) that terminates in vast areas of forebrain and diencephalic limbic areas is responsible for specific generation of aversive arousal and aversive emotional state. This state is accompanied by emission of threatening and/or alarming vocalizations that served as a quantitative measure of the emotional response. The AMCS originates from the cholinergic neurons within the laterodorsal tegmental nucleus that have widespread and diffuse ascending connections. Activity of the AMCS induced by activation of the muscarinic cholinergic receptors in the terminal fields of this system, or by glutamate stimulation of neurons of the laterodorsal tegmental nucleus, brings about aversive state with alarming vocalizations. It is postulated that release of acetylcholine from the terminals of the AMCS in the vast areas of the forebrain and diencephalon serves as the initiator of the aversive emotional state with concomitant manifestations and alarming vocal signaling. It is concluded that the AMCS serves as a specific physiological, psychological, and social arousing and alarming system.

Feeling Better or Doing Better? On the Functions of Inconsistency Reduction (and Other Matters)

In the target article, Travis Proulx and Michael Inzlicht suggest that expectancy violations cause an arousing negative affective state (or aversive arousal) and that humans are motivated to behave...

Moderated Disanxiousuncertlibrium: Specifying the Moderating and Neuroaffective Determinants of Violation-Compensation Effects

abstraction , andthe subsequent iteration of the MMM incorporatedthis compensatory effort into our descriptive taxon-omy (Proulx & Heine, 2010). In later empirical work,we demonstrated that unrelated meaning violations,such as absurd art and mortality threats, increased astate need for simple structure (Proulx, Heine, & Vohs,2010)—as had previously been demonstrated follow-ing violations of personal control (Whitson & Galin-sky, 2008). We took these additional findings as furtherevidencethatdifferentviolationsarebestunderstoodinterms of expected associations, more generally, ratherthan as operating primarily in terms of a specified con-tent, whether it involves human mortality, surreal im-ages, or personal control (the latter account suggestedby Galinsky et al., this issue).Moreover, evidence that these violations bottleneckat a common arousal mechanism can be derived froma number of sources, including the “misattribution ofthe arousal” literature discussed in the target article:Compensation efforts following behavioral dissonance(Zanna & Cooper, 1974), visual anomalies (Proulx &Heine, 2008), and control violations (Kay, Moscov-itch, & Laurin, 2010) are all extinguished if peopleare able to attribute their arousal to a placebo pill, orif they are told that a placebo pill will render themimmune to arousal (Greenberg et al., 2003). More re-cently, Randles, Heine, and Santos (in press) demon-strated that compensatory affirmation following mor-tality reminders and surreal images was extinguishedif participants received an actual pain pill. In general, itappears that all of these violations bottleneck at someform of aversive arousal, with violation–compensationperspectives throughout the field of psychology posit-ing some mode of aversive arousal following the viola-tionagiven belieforgoal.What,then,isthissensation,and is it the same mode of arousal following any givenviolation? Is disequilibrium (Piaget, 1937/1954) thesame as behavioral dissonance (Festinger, 1957)? Isit the same as ideological dissonance (Jost, Pelham,Sheldon, & Sullivan, 2003)? What about its similarityto the “potential terror” that arises from a reminder ofour own mortality (Pyszczynski et al., 1999)?Until we are able to specify this arousal be-yond a kind of “brain phlogiston,” our literature will

The Five “A”s of Meaning Maintenance: Finding Meaning in the Theories of Sense-Making

Across eras and literatures, multiple theories have converged on a broad psychological phenomenon: the common compensation behaviors that follow from violations of our committed understandings. The meaning maintenance model (MMM) offers an integrated account of these behaviors, as well as the overlapping perspectives that address specific aspects of this inconsistency compensation process. According to the MMM, all meaning violations may bottleneck at neurocognitive and psychophysiological systems that detect and react to the experience of inconsistency, which in turn motivates compensatory behaviors. From this perspective, compensation behaviors are understood as palliative efforts to relieve the aversive arousal that follows from any experience that is inconsistent with expected relationships—whether the meaning violation involves a perceptual anomaly or an awareness of a finite human existence. In what follows, we summarize these efforts, the assimilation, accommodation, affirmation, abstraction and assembly behaviors that variously manifest in every corner of our discipline, and academics, more generally.

Dosed versus prolonged exposure in the treatment of fear: An experimental evaluation and review of behavioral mechanisms

Exposure-based treatments have proven effective in treating a range of fears and phobias and can be accounted for by mechanisms described in behavioral theory. Enhanced dosed and dosed-only exposure are promising new behavioral approaches for treating fears and phobias. Thirty-nine participants with speech anxiety were randomly assigned to a prolonged exposure (PE) condition, a positively enhanced dosed exposure (PDE) condition, a dosed-only exposure (DE) condition, or a negatively-supplemented dosed exposure (NDE) condition. Results indicated that both the PDE and DE conditions produced less measured aversive arousal and significantly more rapid arousal reduction than the tested alternatives. These techniques may represent an important advancement, in that the treatment gains of traditional exposure therapies might be achieved without the degree of aversive arousal (and possibly high drop out rates) typically seen in exposure therapies. Additionally, these data contradict prevailing opinion concerning the necessity for sustained aversive arousal during exposure-based treatment.