Estimation Of Average Time Research Articles

Time Perception in Prodromal Alzheimer's Dementia and in Prodromal Dementia With Lewy Bodies.

Background: Time perception is a subjective experience or sense of time. Previous studies have shown that Alzheimer's dementia (AD) patients have time perception deficits compared to a cognitively unimpaired control group (CU). There are only a few studies on dementia with Lewy bodies (DLB) patients' time perception in comparison with CU and AD patients. Early intervention and prescription of the right medicine may delay the deterioration of AD and DLB, moreover, knowing how prodromal AD (prAD) and prodromal DLB's (prDLB) time perception differ from each other might be helpful for future understanding of these two dementias. Therefore, the purpose of this study is to explore the difference in time perception performance between prodromal AD and prodromal DLB.Methods: We invited people diagnosed with prAD, prDLB, and CU to participate in this study. Tests of verbal estimation of time and time interval production were used to assess their time perception. We analyzed the average time estimation (ATE), absolute error score (ABS), coefficient of variance (CV), and subjective temporal unit (STU) within the three groups.Results: A total of 40 prAD, 30 prDLB, and 47 CU completed the study. In the verbal estimation test, the CV for the prAD was higher than both prDLB and CU at the 9 s interval, and the CV of prAD was higher than CU at the 27 s interval. In the time interval production test, the subjective time units of prDLB were higher than prAD at the 10 s interval, while those of both prDLB and CU were higher than prAD at the 30 s interval. The percentage of subjects with STU < 1.0 s, indicating overestimation, was higher in prAD than both prDLB and CU.Conclusion: Time perception of prAD patients showed imprecision and overestimation of time, while prDLB tended to underestimate time intervals. No significant difference was found in accuracy among the three groups. It is speculated that the clinical and pathological severity of the two prodromal dementia stages may be different, and some patients have not yet had their time perception affected.

Operation-triggered quantum clock synchronization

We present a novel quantum clock synchronization(QCS) scheme of multiple parties which uses operation as the trigger to start the evolution of the initial state, where existing QCS protocols use measurement to start the evolution. Since the trigger is the unitary operation, we have protected entanglement of remote nodes, and after concentration of the qubits to the center node, general measurements of the total state is possible. We show that our protocol links the QCS problem to a multiple phase estimation problem. We use the Fisher information to give the precision of the synchronization, and explicitly show that the Heisenberg scale of synchronization is achieved in the two party case. We also show that our protocol is very efficient in synchronizing a clock to the average time of other clocks. The precision has an $O(\sqrt{d})$ advantage of the precision of the average time's estimation over the best possible strategy using measurement triggered QCS. The precision is also Heisenberg scale.