Five different series system configurations with standby units are compared based on their overall reliability and availability. The time-to-failure of a component and its repair time are assumed to have the negative exponential distribution. The mean time-to-failure, MTTF, and the steady-state availability, A T (∞), are obtained for the first three simple configurations and comparisons are performed. For all five configurations, comparisons are made based on assumed numerical values given to the distribution parameters, as well as to the cost of the components. The configurations are ranked based on: MTTF, A T (∞), cost and cost-benefit where benefit is either MTTF or A T (∞).