Auxetic Polyurethane Research Articles

A Split-Plot Experimentation Strategy for Making Causal Inferences in Advanced Materials: Auxetic Polyurethane Foam Manufacturing and Processing Analysis.

Development of advanced materials is often time consuming and expensive because of the large number of variables involved and experiments needed. An effective experimentation strategy would accelerate development by reducing the required amount of experiments without sacrificing the obtainable information. In this paper, the development of auxetic polyurethane (PU) foams was discussed as a case study. Auxetic materials are materials with a negative Poisson's ratio and have potential in many structural and functional applications. Auxetic PU foams are the most studied auxetic materials, and their manufacturing and properties are affected by many processing and environmental factors. This paper introduces a sophisticated design of experimental methodology to help reduce the experimental effort while effectively screening these factors. This methodology is then applied in an experiment to illustrate its utility and distinct advantages that greatly facilitate material development.

Surface Engineering of Auxetic Scaffolds for Neural and Vascular Differentiation from Human Pluripotent Stem Cells.

Auxetic materials are the materials that can display negative Poisson's ratio that describes the degree to which a material contracts (or expands) transversally when axially strained. Human stem cells sense the mechanical properties of the microenvironment, including material surface properties, stiffness, and Poisson's ratio. In this study, six different auxetic polyurethane (PU) foams with different elastic modulus (0.7-1.8kPa) and Poisson's ratio (-0.1 to -0.5) are used to investigate lineage specification of human induced pluripotent stem cells (hiPSCs). The surfaces of the foams are modified with chitosan or heparin to enhance the adhesion and proliferation of hiPSCs. Then, the vascular and neural differentiation of hiPSCs are investigated on different foams with distinct elastic modulus and Poisson's ratio. With different auxetic foams, cells show differential adherent density and differentiation capacity. Chitosan and heparin surface functionalization promote the hindbrain and hippocampal markers, but not forebrain markers during neural patterning of hiPSCs. Properly surface engineered auxetic scaffolds can also promote vascular differentiation of hiPSCs. This study represents a versatile and multifunctional scaffold fabrication approach and can lead to a suitable system for establishing hiPSC culture models in applications of neurovascular disease modeling and drug screening.

A dynamic poroelastic model for auxetic polyurethane foams involving viscoelasticity and pneumatic damping effects in the linear regime

This work proposes a new dynamic poroelastic model to describe the vibration transmissibility of auxetic polyurethane (PU) foams. The model includes the pneumatic damping effect provided by the porous structure of the foam, and the viscoelasticity of the PU material. The auxetic foam is manufactured using a simplified and relatively low-cost uniaxially thermoforming compression technique, which allows the production of a foam with transverse isotropic properties. Stress relaxation, quasi-static cyclic compressive-tensile and seismic base vibration tests in the small strains and linear elastic regimes have been performed in this work. The permeability and the viscoelasticity of the auxetic foams with different thermoforming compression ratios along the thermoforming and transverse directions are identified by performing a nonlinear regression from the mechanical and vibration-derived data. The auxetic foams possess lower stiffness along the thermoforming direction and higher modulus along the transverse one. The moduli of different auxetic foams obtained from quasi-static tests are 40%–70% lower than the corresponding dynamic values estimated from the seismic base excitation, while the static loss factors are all around 20%–100% lower than the corresponding dynamic ones. The enhancements of the dynamic stiffness and damping are mainly caused by the pneumatic damping effect and the viscoelasticity of the PU material. The permeability of the auxetic foam loaded along the thermoforming direction is ∼ 2 times larger than the one of the pristine foam, but 50% smaller when the foam is dynamically loaded along the transverse direction, due to the transverse isotropic microstructure of this porous material.

Effects of geometrical and processing parameters on mechanical properties of auxetic polyurethane foams

This study aimed to investigate the influence of processing parameters on the mechanical properties of auxetic polyurethane foams including Poisson’s ratio and Young’s modulus. 12 different processing scenarios were considered using the method of Plackett–Burman in the design of experiments with three replicates for each one. Eventually, 36 foams were prepared with different densities and initial thicknesses, heating temperatures and times, applied compression ratios, and the rest times between two heating steps. The microstructures of the conventional and auxetic samples were observed by scanning electron microscopy (SEM). All samples were subjected to tensile loading in one direction with two different strain values. The strains of the foams in two other directions were recorded using a digital image correlation method. Also, the required force to create each strain value was recorded. The results showed that depending on the changing parameters, Poisson’s ratio of about 42% and 58% of the samples reduced at the strains of 10% and 20%, respectively. Heating temperature and time, the initial thickness of the foam, and the applied compression ratio were proved to have significant effects on the variations of both Poisson’s ratio and Young’s modulus of the foams. It was concluded that the Poisson’s ratio of foams was reduced at higher heating temperature, time, and applied compression ratio and also a lower foam initial thickness. On the other hand, these changes increased Young’s modulus of the polyurethane foams. The strain energy of the auxetic samples showed higher amounts of energy compared to the other foams.

Geometrically modified auxetic polyurethane foams and their potential application in impact mitigation of masonry structures

Hollow block masonry buildings constructed alongside busy roads are vulnerable to vehicular impacts resulting in damage to property and harm to the building and vehicle occupants. This paper presents a method for the design and insertion of various forms of geometrically modified auxetic foam structures inside the hollow cores of block masonry walls for mitigating the adverse effects of such impacts. Due to the low tensile strength of masonry, the insertion material should possess high energy absorption characteristics and high strength for impact damage mitigation which can be achieved through auxetic foams with negative Poisson’s ratio. To this end, finite element models of geometrically modified auxetic foams (GMAFs) are developed by inserting thin polyester sheets and hollow acrylonitrile butadiene styrene (ABS) tubes of various geometries into conventional polyurethane foams. The proposed geometrical configurations of inserted tubes and sheets result in auxetic behaviour of the conventional foam with a maximum negative Poisson’s ratio of about −12. These foam models are validated analytically and then employed to model masonry walls with auxetic foam insertions in the hollow cores of blocks. These masonry wall models are then analysed under high-velocity lateral impacts. Results show the beneficial change in the failure mechanism of the masonry walls which altered from severe damage of wall face to the rebound of the impactor without penetration by reducing the displacement by four times, due to the presence of the auxetic foam insertions. This phenomenon occurred due to the significant energy dissipation caused by the combined effects of the re-entrant shaped hollow tubes and thin polyester sheet arrangements in the GMAF. Outcomes of this study will contribute towards safer masonry buildings along busy road fronts.

Study of castor oil‐based auxetic polyurethane foams for cushioning applications

AbstractThis work involves the study of mechanical and antibacterial properties of auxetic polyurethane (APU) foams synthesized using castor oil (CO) to ascertain their suitability as seat cushions in wheelchairs. Firstly, CO‐based PU foams (PU‐CO) were synthesized by substituting 25% synthetic polyol with CO in a polyol blend. Conventional PU foams and PU‐CO foams were then converted to auxetic foams using triaxial compression and heating. The chemical composition, microstructure and thermal, mechanical and antibacterial properties of the foams were analyzed. It was found that addition of CO improved the antibacterial and mechanical properties of the foams. CO‐based APU (CO‐APU) foams showed highest compression strength and storage modulus. An increase in thermal stability of PU‐CO was also observed as compared to PU foams. These CO‐APU foams could be a better alternative to conventional PU foams for wheelchair seat cushions and in hospital bed applications. © 2021 Society of Industrial Chemistry.

Study of silver nanoparticle-loaded auxetic polyurethane foams for medical cushioning applications

Patients who are bed-ridden and users of wheelchairs are prone to development of pressure sores at the cushion–skin interface due to stress concentrations, moisture and bacterial infections. The purpose of this work is to develop antibacterial auxetic polyurethane (PU) foams for use in seat cushions and hospital beds. Silver nanoparticles (SNPs) were used in the synthesis of PU foams to induce antibacterial properties. These foams were then converted to negative Poisson’s ratio or auxetic polyurethane (APU) foams to improve the mechanical properties. Two different APU foams were made using compression factors of 2.07 and 2.97. Chemical composition, microstructure, thermal, mechanical and antibacterial properties of SNP-based PU foams before and after conversion to APUs were studied. The study showed that APU foams fabricated using higher compression factor greatly enhanced the antibacterial properties against gram positive (Staphylococcus aureus and Staphylococcus epidermidis) and gram negative (Pseudomonas aeruginosa and Escherichia coli) bacteria. APU foams made using higher compression ratio also exhibited increase in the compression strength at higher strains (after 20% strain). This study shows that the antibacterial APU foams developed in this work can possibly cause less infection and ensure better stress distribution at the cushion–skin interface.

A self-powered smart safety belt enabled by triboelectric nanogenerators for driving status monitoring

Driving status monitoring is highly desirable to ensure safety and prevent traffic accidents. Unsafe and inappropriate driving behaviors can be identified through the monitoring of the driver's body motion. A self-powered smart safety belt composed of two types of triboelectric nanogenerators (TENGs) is developed to monitor the forward position and turning actions of the driver. An auxetic Polyurethane (APU) –TENG integrated in the horizontal strip of the safety belt achieves high sensitivity (0.89V/cm2) for strain measurements in the large strain domain (40%–100%), enabling the long range monitoring of the forward position of the driver, which correlates to abrupt and aggressive deceleration. Two sensor arrays of arch-shaped TENGs (AS-TENGs) attached to shoulder and waist location of the diagonal strip in the safety belt can measure the turning directions and angles of the driver, respectively. The AS-TENGs are designed through the integration of two TENGs in the top and bottom arch, respectively, to ensure stable and gradually increased contact between the triboelectric layers in both arches, which leads to a high displacement measurement sensitivity of 47.2V/cm3 with high linearity. This work demonstrates an effctive approach to integrate self-powered TENGs sensors seamlessly into existing driving environment for driving status monitoring, expanding the applictions of TENGs in wearable electronics.

Mechanical behaviors of auxetic polyurethane foam at quasi-static, intermediate and high strain rates

We experimentally determined the uniaxial compressive stress-strain responses of an auxetic polyurethane (PU) foam at quasi-static (0.01/s), intermediate (1/s, 10/s and 745/s) and high (1430/s, 1870/s and 2290/s) strain rates. A hydraulically driven materials testing system (MTS) was used to perform the experiments at the strain rate of 0.1/s, 1/s and 10/s, while higher intermediate (745/s) and high strain-rate compressive loadings were introduced using long and regular Kolsky bars, respectively. The Poisson effect of the auxetic PU foam was also investigated during the experiments using a precision LED optical micrometer system (OMS) (0.01/s–10/s) or an ultra-high speed camera (745/s–2290/s). Our results show that the compressive stress-strain curves of the auxetic PU foam are non-linear and strain-rate sensitive. In all the experiments, the Poisson's ratio, with an initial negative value at small strains, progressively increased toward 0 as the specimen was further compressed. The strain-rate effect on the material's Poisson's ratio is also evident in our study, as the specimens subjected to high strain-rate loadings exhibited smaller negative Poisson's ratios (NPR) in absolute sense at small strains in comparing with those at quasi-static and intermediate strain rates.

Influence of energy absorbers on Malgaigne fracture mechanism in lumbar-pelvic system under vertical impact load

Malgaigne fractures are the most common and widespread pelvic injuries resulting from the shear forces the action mechanism of which has not been explained in the literature yet. Military accidents with improvised explosive devices (IED) perfectly reflect this type of pelvic fracture. The finite element (FE) model of lumbar-pelvic complex (LPC) was developed based on computed tomography (CT) scans with the seat including steel frame, padding and soft tissue. The correlation coefficients of both low (100 N) and high (500 N) loads were greater than that currently obtained in the literature due to the presence of muscle force, pubic symphysis and joint cartilage. The dynamic analysis was performed to determine the influence of varying kinds of foam materials i.e. polyurethane, aluminium honeycomb structured and polyurethane auxetic foam on the stress/strain distribution in LPC under vertical impact load with the velocity of 7 m/s. Performed analysis showed the first fracture occurred in the L5 vertebrae resulting in the sacroiliac ligaments disruption and stress concentration in the pelvic ring causing further fractures of the wing of ilium, pubis and ischium bones. This results clearly explain the inconclusive findings about the second fracture that occurs in the pelvic area under a vertical impact load. The applied seat padding foam significantly reduced the stresses transmitted to the anatomical structures, thereby avoiding the risk of pelvic fracture. The analysis has proven that the auxetic polyurethane foam can be used as a good energy absorber.

Vascular differentiation from pluripotent stem cells in 3-D auxetic scaffolds.

Auxetic scaffolds, that is, scaffolds that can display negative Poisson's ratio, have unique physical properties and can expand transversally when axially strained or contract under compression. Auxetic materials have been used for bioprostheses and artery stents due to the enhanced compressive strength and shear stiffness. In vascular tissue engineering, auxetic scaffolds allow the widening of blood vessels when blood flows through (creating compressive stress) to prevent the blockage. However, the influence of auxetic materials on the cellular fate decision in local environment is unclear. In this study, auxetic polyurethane foams were used to support vascular differentiation from pluripotent stem cells. The expression of alkaline phosphatase, Oct-4, and Nanog was lower after 4days of differentiation for the cells grown in auxetic scaffolds. Higher expression of vascular markers CD31 and VE-cadherin was observed for the cells from auxetic scaffolds compared with those from the scaffolds before auxetic conversion. Little influence on the expression of cardiac marker α-actinin was observed. The vascular cells secreted extracellular matrix proteins vitronectin and laminin and expressed membrane-bound matrix metalloproteinase 9. The examination of Yes-associated protein expression indicated more cytoplasmic retention in the cells from auxetic scaffolds compared with those from regular scaffolds, suggesting that the auxetic scaffolds may affect cellular contraction. This study demonstrates a novel 3-D culture based on auxetic scaffolds for vascular differentiation and provides a platform to study the influence of biophysical microenvironments on differentiation of pluripotent stem cells. The outcome of this study has implications for regenerative medicine and drug discovery.

Auxetic polyurethane foams – method for determining a softening point

Abstract The article described selected methods for determining a softening point of plastics (polymers). The way of determining a softening point of polyurethane foams was suggested. Moreover, the influence of annealing temperature of an auxetic polyurethane foam on its volume was presented.

Auxetic Foam‐Based Contact‐Mode Triboelectric Nanogenerator with Highly Sensitive Self‐Powered Strain Sensing Capabilities to Monitor Human Body Movement

The first contact‐mode triboelectric self‐powered strain sensor using an auxetic polyurethane foam, conductive fabric, and polytetrafluroethylene (PTFE) is fabricated. Utilizing the auxetic properties of the polyurethane foam, the auxetic polyurethane foam would expand into the PTFE when the foam is stretched, causing contact electrification. Due to a larger contact area between the PTFE and the foam as the foam is stretched, this device can serve effectively as a strain sensor. The sensitivity of this method is explored, and this sensor has the highest sensitivity in all triboelectric nanogenerator devices that are used previously as a strain sensor. Different applications of this strain sensor are shown, and this sensor can be used as a human body monitoring system, self‐powered scale to measure weight, and a seat belt to measure body movements inside a car seat.

Macro-scale model study of a tunable drug dispensation mechanism for controlled drug delivery in potential wound-healing applications.

Auxetic materials tend to exhibit stretching in the direction of the applied load as well as in the perpendicular direction. This may be an inherent property of the material, or it might be a particular structural characteristic that confers it with auxetic properties. In this study, the auxetic properties of a rotating squares auxetic design were utilized in tandem with a stretching mechanism to manufacture a device that offers the advantages of adjustable pore size and hence tunable drug delivery characteristics. An auxetic polyurethane film was fabricated through the polymer casting technique. An acrylonitrile-butadiene-styrene (ABS) plastic mold for polymer casting was made through additive manufacturing. Stereolithography was used for fabrication of the mechanism that controlled pore size of the polymeric auxetic film. A laminate arrangement of the film and the mechanism was devised, through which movement of the mechanism controlled stretching of the auxetic film underneath. Results were analyzed through image processing. It was observed that a 2-dimensional increase (in length and width) of the auxetic film took place that corresponded to an increase in pore size of the film. Several mathematical correlations were drawn up. It may be concluded that the first factor controlling drug release kinetics is the pore size of the film. This study explored a prototype mechanism that has the potential for being used in devices for controlled drug delivery or in smart bandage systems that may enhance wound healing in chronic wound treatment.

Pluripotent stem cell expansion and neural differentiation in 3-D scaffolds of tunable Poisson's ratio.

Biophysical signaling from the substrates and scaffolds plays a critical role in neural lineage commitment of pluripotent stem cells. While the contribution of elastic modulus has been well studied, the influence of Poisson's ratio along with microstructure of the scaffolds remains unknown largely due to the lack of technology to produce materials with tailorable Poisson's ratio. This study fabricated auxetic polyurethane scaffolds with different elastic modulus, Poisson's ratio and microstructure and evaluated neural differentiation of pluripotent stem cells. The findings add a novel angle to understand the impact of biophysical microenvironment on stem cell fate decisions.

On the successful fabrication of auxetic polyurethane foams: Materials requirement, processing strategy and conversion mechanism

This study aims to provide fundamental understandings in several issues critical to the fabrication of auxetic polyurethane (PU) foams by thermal compression process: conversion and auxetic structure fixation mechanisms, materials characteristics essential for the successful auxetic conversion, and optimal conditions for auxetic conversion. Three flexible PU foams with similar morphology were selected for the study. First the commonalities as well as the differences between these foams in terms of their chemical composition, microstructure and thermomechanical properties were thoroughly analyzed. This is followed by the auxetic convertibility study of these three foams. Mechanisms for fixing the structure were elucidated and the windows for processing were interpreted in the context of polymer relaxation. Guided by these understandings, a series of auxetic foams were manufactured at a wide range of conditions. The processing conditions agreed very well with those suggested from the mechanistic investigation, validating the proposed auxetic conversion and structure fixation mechanisms. The mechanism was further confirmed by direct observation of the morphology of the fabricated auxetic foams.

Auxetic polymeric bone plate as internal fixator for long bone fractures: Design, fabrication and structural analysis.

Injuries cover about 11% of World's Disease Burden depicting fractures to be the leading severe consequence of trauma. Fractures occur due to force impact or osteoporosis. Fracture healing is a complicated process. Fracture fixation techniques focus on imparting reduction to fractured fragments and induce healing. When considering possible fixation methods, the aspect of micro-movement is an important one, as this induces callus formation which tends to be a crucial step for fracture healing. Internal fixation of long bone fractures using metallic plates has been carried out since decades and recently advancements have been in synthesizing biodegradable plates as well. The purpose of this research was to fabricate an Auxetic Polymeric Bone Plate that can be used as an internal fixator for long bone fracture; this bone plate renders micro-movement due to its counter intuitive behavior, has the potential to reduce the effect of stress shielding and allow the same range of motion as that of natural bone. Polyurethane was chosen as a material for the fabrication of the Auxetic device because of its biocompatibility and non-toxic effects. The plate was then tested for mechanical properties such as Tensile and Compression testing to determine the strength. The tensile testing of the Auxetic polyurethane specimens showed that the mean of the Poisson's ratio of the samples lies between -0.68 and -0.87 at different uni-axial tensile load values. The Auxetic structure of our device has the potential to allow for efficient fixation because its negative Poisson's ratio offers micro-movement, thereby causing fixation with relative stability rather than absolute stability. The Auxetic bone plate can be superior to contemporary plate fixation systems, as it demands meaningfully small contact points. The suitable mechanical properties might lessen stress shielding effects that are normally caused by rigid bone plates. The Auxetic nature of the bone will help align and sustain the bone fragments with small fracture gaps in order to impart appropriate assembly to accomplish bone healing.

Characterization of auxetic polyurethanes foam for biomedical implants

AbstractAging, accidents and diseases are the leading causes of disability in today’s world. Therefore, implants and prostheses for hard and soft tissues are becoming increasingly common to restore daily activity and improve the quality of life of patients. Although implants have been extensively developed and are in the clinical use, deformation mechanism, inflexibility and mismatch of the elastic and mechanical behavior of the implants with native tissues are challenges for tissue engineering. The objective of this study was to characterize auxetic polyurethane foam as an auxetic soft tissue implant based on mathematical modeling using a nonlinear elasticity theory. The compressibility effects on auxetic soft tissue implants due to equibiaxial loading were studied. Numerical results were computed using experimentally obtained data and compared with the non-auxetic behavior of a soft tissue.

Auxetic polyurethane stents and stent-grafts for the palliative treatment of squamous cell carcinomas of the proximal and mid oesophagus: A novel fabrication route

Squamous cell carcinoma is usually cancer of the upper oesophagus and is very aggressive cancer. The cancer of the cervical oesophagus causes a serious complication called dysphagia, which is difficulty in eating or swallowing and which is indicative of incurability. Oesophageal stents have been used as a relatively better palliative method for patients who are suffering from advanced stage squamous cell carcinomas of oesophagus and also for the effective relief of dysphagia. There are still problems in currently available self-expanding metals and plastic stents, which are associated with high rates of early and late complications. This research work is aimed to use Auxetic (rotating-squares) geometry for the production of a novel Auxetic oesophageal stents and stent-grafts relevant to the palliative treatment of squamous cell carcinomas of the proximal and mid oesophagus and also for the prevention of dysphagia. This study also endeavoured to manufacture a significantly small diameter Auxetic oesophageal stent and stent-graft. In order to easily deploy the Auxetic stent orally using a commercial balloon dilatational catheter, and hence it also obviates the need of an expensive dedicated delivery system. A novel manufacturing route was employed in this research to develop both Auxetic films and Auxetic oesophageal stents, which ranged from conventional subtractive techniques to new generative manufacturing methods. Polyurethane was selected as a material for the fabrication of Auxetic films and Auxetic oesophageal stents because of its good biocompatibility and non-toxicological properties. The developed Auxetic films were later used for the fabrication of seamed Auxetic oesophageal stents. The flexible polyurethane tubular grafts were also attached to the inner luminal side of the seamless Auxetic oesophageal stents, in order to prevent tumour in-growth.

Auxetic oesophageal stents: structure and mechanical properties

Oesophageal cancer is the ninth leading cause of malignant cancer death and its prognosis remains poor, ranking as the sixth most frequent cause of death in the world. This research work aims to adopt an Auxetic (rotating-squares) geometry device, that had previously been examined theoretically and analysed by Grima and Evans (J Mater Sci Lett 19(17):1563-1565, 2000), to produce a novel Auxetic oesophageal stent and stent-grafts relevant to the palliative treatment of oesophageal cancer and also for the prevention of dysphagia. This paper discusses the manufacture of a small diameter Auxetic oesophageal stent and stent-graft. The oral deployment of such an Auxetic stent would be simplest if a commercial balloon dilatational catheter was used as this obviates the need for an expensive dedicated delivery system. A novel manufacturing route was employed in this research to develop both Auxetic films and Auxetic oesophageal stents, which ranged from conventional subtractive techniques to a new additive manufacturing method. Polyurethane was selected as a material for the fabrication of Auxetic films and Auxetic oesophageal stents because of its good biocompatibility and non-toxicological properties. The Auxetic films were later used for the fabrication of seamed Auxetic oesophageal stents. The flexible polyurethane tubular grafts were also attached to the inner luminal side of the seamless Auxetic oesophageal stents, in order to prevent tumour in-growth. Scanning electron microscopy was used to conduct surface morphology study by using different Auxetic specimens developed from different conventional and new additive manufacturing techniques. Tensile testing of the Auxetic films was performed to characterise their mechanical properties. The stent expansion tests of the Auxetic stents were done to analyse the longitudinal extension and radial expansion of the Auxetic stent at a range of radial pressures applied by the balloon catheter, and to also identify the pressure values where the Auxetic stent fails. Finite element models of both Auxetic film and Auxetic stent were developed, and the results were compared with experimental results with a good agreement. The tensile testing of the Auxetic polyurethane films revealed that the Poisson's ratio of the sample ranged between -0.87 and -0.963 at different uniaxial tensile load values. From the stent expansion test, it was found that the Auxetic oesophageal stent radially expanded from 0.5 to 5.73mm and longitudinally extended from 0.15 to 1.83mm at a range of applied pressure increments (0.5-2.7bar) from the balloon catheter.