Automatic Tube Potential Selection Research Articles

Task-based automatic keV selection: leveraging routine virtual monoenergetic imaging for dose reduction on clinical photon-counting detector CT * *Portions presented at RSNA 2021 and 2022.

Objective. Photon-counting detector (PCD) CT enables routine virtual-monoenergetic image (VMI) reconstruction. We evaluated the performance of an automatic VMI energy level (keV) selection tool on a clinical PCD-CT system in comparison to an automatic tube potential (kV) selection tool from an energy-integrating-detector (EID) CT system from the same manufacturer. Approach. Four torso-shaped phantoms (20–50 cm width) containing iodine (2, 5, and 10 mg cc−1) and calcium (100 mg cc−1) were scanned on PCD-CT and EID-CT. Dose optimization techniques, task-based VMI energy level and tube-potential selection on PCD-CT (CARE keV) and task-based tube potential selection on EID-CT (CARE kV), were enabled. CT numbers, image noise, and dose-normalized contrast-to-noise ratio (CNRd) were compared. Main results. PCD-CT produced task-specific VMIs at 70, 65, 60, and 55 keV for non-contrast, bone, soft tissue with contrast, and vascular settings, respectively. A 120 kV tube potential was automatically selected on PCD-CT for all scans. In comparison, EID-CT used x-ray tube potentials from 80 to 150 kV based on imaging task and phantom size. PCD-CT achieved consistent dose reduction at 9%, 21% and 39% for bone, soft tissue with contrast, and vascular tasks relative to the non-contrast task, independent of phantom size. On EID-CT, dose reduction factor for contrast tasks relative to the non-contrast task ranged from a 65% decrease (vascular task, 70 kV, 20 cm phantom) to a 21% increase (soft tissue with contrast task, 150 kV, 50 cm phantom) due to size-specific tube potential adaptation. PCD-CT CNRd was equivalent to or higher than those of EID-CT for all tasks and phantom sizes, except for the vascular task with 20 cm phantom, where 70 kV EID-CT CNRd outperformed 55 keV PCD-CT images. Significance. PCD-CT produced more consistent CT numbers compared to EID-CT due to standardized VMI output, which greatly benefits standardization efforts and facilitates radiation dose reduction.

Procedure for optimal implementation of automatic tube potential selection in pediatric CT to reduce radiation dose and improve workflow.

It is important to employ radiation dose reduction techniques in pediatric computed tomography (CT) to reduce potential risks of radiation‐induced malignancy. Automatic tube potential (kV) selection tools have been developed and become available on many CT scanners, which select the optimum kV based on the patient size and clinical task to improve the radiation dose efficiency. However, its use in pediatric CT has been mostly empirical, following manufacturer’s default recommendation without solid demonstration for quality improvement. This study aimed to implement an automatic tube potential tool (CAREkV, Siemens Healthcare) into routine pediatric CT practice, using the “Plan‐Do‐Study‐Act” quality improvement process, in place of an existing kV/mAs technique chart. The design of this quality improvement project involved Plan‐Do‐Study‐Act stages. Plan and Do stages identified the criteria for optimal automatic kV selection; a range of phantoms representing typical pediatric groups were scanned on a dual‐source 128‐slice scanner using a fast‐pitch scanning mode. The identified CAREkV settings were implemented into the CT protocol and evaluated after a 6‐month period. In the Study stage, an objective evaluation of the image metrics and radiation dose for two similar patient cohorts using CAREkV and the technique‐chart, respectively, were compared. The kV selected, image quality and radiation dose determined by CAREkV were comparable to those obtained while using the technique‐chart. The CAREkV was successfully implemented into our pediatric abdominopelvic CT practice. By utilizing the “PDSA” process optimal image quality and radiation dose reduction were achieved with an automatic kV selection tool to improve CT workflow.

Optimization of paranasal sinus CT procedure: Ultra-low dose CT as a roadmap for pre-functional endoscopic sinus surgery.

To assess image quality and radiation dose associated with ultra-low dose CT protocol for patients with benign paranasal sinus diseases undergoing functional endoscopic surgery (FESS). We scanned the head portion of Alderson RANDO phantom on a second generation, dual-source, multidetector-row CT scanner (Siemens Definition Flash) using standard-dose and five low-dose protocols. Two radiologists assessed the image quality for each protocol to determine best ultra-low-dose protocols for imaging patients with benign paranasal sinus diseases undergoing FESS. The ultra-low-dose CT protocols were then used for scanning. Thereafter, 40 adult patients (age range 18-54years, M:F 23:17) were scanned with the four low dose scanning protocols (10 patients per protocol). On both transverse and coronal reformatted CT images, two radiologists assessed visibility of key anatomic landmarks for FESS on a 2-point scale (1=clear and complete visualization; 2=suboptimal visualization). Data were analyzed with descriptive statistics and Cohen's kappa coefficient for interobserver agreement. In phantom study, the lowest dose scan protocol (CTDIvol 2.1mGy, 70kV, 75 mAs) was unacceptable due to poor image quality. For patient studies, both radiologists gave acceptable image quality scores for ultra-low-dose scan protocol with axial scan mode, automatic tube potential selection and tube current modulation (CTDIvol 2.2mGy; DLP 22.9mGy.cm) with up to 60% lower dose compared to prior standard-dose CT (CTDIvol 5.3mGy; DLP 73.5mGy.cm). Ultra-low-dose CT protocol provides sufficient image quality for scanning patients undergoing functional endoscopic surgery for benign paranasal sinus diseases.

Relation between age and CT radiation doses: Dose trends in 705 pediatric head CT

PurposeTo evaluate the relationship between patient age and radiation doses associated with routine pediatric head CT performed with automatic tube potential selection and tube current modulation techniques. MethodsWe obtained patient demographics, scan parameters, and radiation dose descriptors (CT dose index volume -CTDIvol and dose length product -DLP) associated with consecutive routine head CT in 705 children (mean age 6.9 ± 5 years). Children were scanned on one of the three multidetector-row CTs (64–128 slices, Siemens) over 6 months period in a tertiary hospital. All head CT exams were performed in helical scan mode using automatic tube potential selection (Care kV) and automatic tube current modulation (Care Dose 4D) techniques. The information was obtained from a radiation dose monitoring software. Data were analyzed using linear correlation and analysis of variance. ResultsMost age-wise median CTDIvol (9−27 mGy; 703/705 pediatric head CT, >99 %) from our institution were lower than the European Diagnostic Reference Levels (EDRL, CTDIvol 24−50 mGy) but median DLP (151−586 mGy cm) from 201/705 children (28 %) was higher than the EDRL (DLP 300−650 mGy cm). Unlike the age-stratified EDRL, a combination of automatic tube potential selection and tube current modulation for pediatric head results in a significant linear correlation between radiation doses and patient age (r2 = 0.66, p < 0.001). ConclusionsRadiation doses for head CT change linearly with children's age. Despite lower CTDIvol and DLP for most children, longer scan length resulted in higher DLP for some pediatric head CT compared to the corresponding EDRL; this result underscores the need to promote clear guidelines for technologists operating CT.

Automatic tube potential selection with tube current modulation in coronary CT angiography: Can it achieve consistent image quality among various individuals?

The present study included a total of 111 consecutive patients who had undergone coronary computed tomography (CT) angiography, using a first-generation dual-source CT with automatic tube potential selection and tube current modulation. Body weight (BW) and body mass index (BMI) were recorded prior to CT examinations. Image noise and attenuation of the proximal ascending aorta (AA) and descending aorta (DA) at the middle level of the left ventricle were measured. Correlations between BW, BMI and objective image quality were evaluated using linear regression. In addition, two subgroups based on BMI (BMI ≤25 and >25 kg/m2) were analyzed. Subjective image quality, image noise, the signal-to-noise ratio (SNR) and the contrast-to-noise ratio (CNR) were all compared between those. The image noise of the AA increased with the BW and BMI (BW: r=0.453, P<0.001; BMI: r=0.545, P<0.001). The CNR and SNR of the AA were inversely correlated with BW and BMI, respectively. The image noise of the DA and the CNR and SNR of the DA exhibited a similar association to those with the BW or BMI. The BMI >25 kg/m2 group had a significant increase in image noise (33.1±6.9 vs. 27.8±4.0 HU, P<0.05) and a significant reduction in CNR and SNR, when compared with those in the BMI ≤25 kg/m2 group (CNR: 18.9±4.3 vs. 16.1±3.7, P<0.05; SNR: 16.0±3.8 vs. 13.6±3.2, P<0.05). Patients with a BMI of ≤25 kg/m2 had more coronary artery segments scored as excellent, compared with patients with a BMI of >25 kg/m2 (P=0.02). In conclusion, this method is not able to achieve a consistent objective image quality across the entire patient population. The impact of BW and BMI on objective image quality was not completely eliminated. BMI-based adjustment of the tube potential may achieve a more consistent image quality compared to automatic tube potential selection, particularly in patients with a larger body habitus.

Attenuation-Based Automatic Tube Potential Selection in Cerebral Computed Tomography Angiography: Effects on Radiation Exposure and Image Quality

Attenuation-Based Automatic Tube Potential Selection in Cerebral Computed Tomography Angiography: Effects on Radiation Exposure and Image Quality

Scout-Based Automated Tube Potential Selection Technique (kV Assist) in Enhanced Chest Computed Tomography: Effects on Radiation Exposure and Image Quality.

The aim of our study was to assess radiation dose reduction and image quality for enhanced chest CT examinations with a scout-based automated tube potential selection technique (kV Assist) compared with a standard 120-kV protocol. Prospective study of enhanced chest CT examinations was performed in 100 consecutive patients with kV Assist and in 100 consecutive patients with conventional 120-kV protocol on a multislice CT (Discovery CT750 HD). The body mass index, CT dose index volume, and dose length product were recorded from the examination protocol. Image noise and CT value was measured on region of interest, signal-to-noise ratio, and contrast-to-noise ratio was calculated. The subjective image quality was assessed by two radiologists blinded to the respective protocol with the use of a 3-grade scale (3, superior quality; 2, moderate quality; 1, inferior quality). With kV Assist, the percentages of patients being scanned using 80, 100, and 120 kV were 12.0%, 80.0%, and 8.0%, respectively. The kilovolt setting was related with body mass index (r = 0.565, P = 0.000). Compared with the conventional 120 kV protocol, kV Assist allowed for an overall average decrease of 30.6% in CT dose index volume (kV Assist, 11.05 ± 4.78 mGy; 120 kV, 15.92 ± 6.89 mGy) (P < 0.001) and 32.3% in dose length product (kV Assist, 386.41 ± 184.02 mGy cm; 120 kV, 571.14 ± 286.68 mGy cm) (P < 0.001). In the kV Assist, mean attenuation of regions of interest inside the aorta was significantly higher than that in 120-kV protocols (kV Assist, 310.27 ± 73.70 HU; 120 kV, 239.44 ± 47.65 HU) (P < 0.001), resulting in increased contrast-to-noise ratio (kV Assist, 26.69 ± 7.78; 120 kV, 21.38 ± 6.05) (P < 0.001). There was no significant difference in subjective image quality scores between the 2 groups. The use of attenuation-based kV Assist technique enables significant dose reduction in enhanced chest CT scan while improving arterial enhancement and preserving image quality at adequate levels.

Initial Experience of the Application of Automated Tube Potential Selection Technique in High-pitch Dual-source CT Angiography of Whole Aorta Using Third-generation Dual-source CT Scanner.

Objective To evaluate the application of automated tube potential selection technique in high-pitch dual-source CT aortic angiography on a third-generation dual-source CT scanner. Methods Whole aorta angiography were indiated in 59 patients,who were divided into 2 groups using a simple random method:in group 1 there were 31 patients who underwent the examination with automated tube potential selection using a vascular setting with a preferred image quality of 288 mA/100 kV;in group 2 there were 28 patients who underwent the examination with a tube voltage of 100 kV and automated tube current modulation using a reference tube current of 288 mA. Both groups were scanned on a third generation dual-source CT device operated in dual-source high-pitch ECG-gating mode with a pitch of 3.0,collimation of 2×192×0.6 mm,and a rotation time of 0.25 s. Iterative reconstruction algorithm was used. For group 1,the volume and flow of contrast medium and chasing saline were adapted to the tube voltage. For group 2,a contrast material bolus of 45 ml with a flow of 4.5 ml/s followed by a 50 ml saline chaser at 5 ml/s was used. CTA scan was automatically started using a bolus tracking technique at the level of the original part of aorta after a trigger threshold of 100 HU was reached. The start delay was set to 6 s in both groups. Effective dose (ED),signal to noise ratio (SNR),contrast to noise ratio (CNR),and subjective diagnostic quality of both groups were evaluated. Results The mean ED were 21.3% lower (t=-3.099,P=0.000) in group 1 [(2.48±0.80) mSv] than in group 2 [(3.15±0.86) mSv]. Two groups showed no significant difference in attenuation,SD,SNR,or CNR at all evaluational parts of aorta (ascending aorta,aortic arch,diaphragmatic aorta,or iliac bifurcation)(all P>0.05). There was no significant difference in subjective diagnostic quality values of two groups [(1.41±0.50) scores vs. (1.39±0.50) scores;W=828.5,P=0.837]. Conclusion Compared with automated tube current modulation,the automated tube potential selection technique in aorta CT angiography on a third-generation dual-source CT can dramatically reduce radiation dose without affecting image quality.

Optimization of the pediatric head computed tomography scan image quality: Reducing dose with an automatic tube potential selection in infants

The objective of our study was to evaluate the impact of an automatic tube potential selection (ATPS) on the delivered dose and image quality in unenhanced head computed tomography (CT) scans of infants. Unenhanced head CT scans were acquired before and after the introduction of an ATPS in full automatic mode in two groups of 20 patients under one year of age. The delivered dose (CDTIvol) as the quantitative (contrast-to-noise ratio) and qualitative (based on the European CT criteria) image quality were compared on the supra- and infratentorial regions by three senior pediatric radiologists. Mann-Whitney and Fisher exact tests were performed. An interobserver Fleiss's kappa agreement was calculated for each criterion. The use of an ATPS allowed a significant reduction in the delivered dose (-21%, p=0.0005) with no significant difference of the contrast-to-noise ratio in supra- (-5%, p=0.21) and infratentorial regions (+16%, p=0.96). In all cases, dose reduction was obtained with the same value of 100kV. It maintained a good qualitative image quality (e.g., differentiation between gray and white matter in supra-tentorial region: p=0.470). The interobserver Fleiss's kappa agreements were good to excellent. ATPS is a tool that can significantly reduce the delivered dose by choosing the most appropriate tube voltage while maintaining image quality in unenhanced head CT scans of infants.

Dealing with Uncertainty in CT Images

New acquisition and reconstruction methods, such as automated tube potential selection, dual-energy acquisitions, and iterative reconstruction, certainly increase the variability possible in quantitative measurements, but these limitations should be readily accepted if they provide an avenue toward improving patient benefit by improving diagnostic performance or minimizing potential risk from radiation or intravenous contrast material.

Low-dose CT angiography of the abdominal aorta and reduced contrast medium volume: Assessment of image quality and radiation dose

To determine the effect of using 80kV tube voltage and a reduced amount of contrast medium on the image quality and radiation dose of computed tomography angiography (CTA) of the abdominal aorta. Patients who were referred for a CTA examination of the abdominal aorta were included in this technical efficacy study. Thirty patients were divided randomly into two groups. Fifteen patients underwent a dual-energy CT (DECT) protocol (Group A). Fifteen patients were scanned with the use of an automated tube potential selection algorithm tool (Group B). In both protocols, a test bolus injection of 10ml ioversol (350mg iodine/ml) was used, followed by 20ml of 1:1 saline-diluted contrast medium. Quantitative analysis comprised determination of the mean attenuation and contrast-to-noise ratio. Qualitative image analysis was performed independently by five radiologists. The estimated radiation dose in terms of CT dose index and effective dose was recorded and compared with a standard 120kV protocol. In Group B, six patients underwent CTA at 80kV, seven patients underwent CTA at 100kV and two patients underwent CTA at 120kV. The mean contrast-enhancement values of Group A (80kV) and the 80kV subgroup of Group B were 16.5% and 27.6% higher compared to the 100kV subgroup of Group B, these differences were, however, not significant. There were no significant differences in mean image quality between groups. In patients undergoing CTA at 80kV the effective dose decreased by up to 51.3% compared to a conventional 120kV CTA protocol. The findings of this study support the hypothesis that 80kV in CTA of the abdominal aorta can reliably be used with only 30ml contrast medium in total and a 50% reduction in radiation dose. The overall image quality was diagnostically adequate; however, it appeared to be suboptimal in patients with a BMI above 28kg/m(2).

Effects of automatic tube potential selection on radiation dose index, image quality, and lesion detectability in pediatric abdominopelvic CT and CTA: a phantom study.

To assess the effect of automatic tube potential selection (ATPS) on radiation dose, image quality, and lesion detectability in paediatric abdominopelvic CT and CT angiography (CTA). A paediatric modular phantom with contrast inserts was examined with routine pitch (1.4) and high pitch (3.0) using a standard abdominopelvic protocol with fixed 120 kVp, and ATPS with variable kVp in non-contrast, contrast-enhanced, and CTA mode. The volume CT dose index (CTDIvol), contrast-to-noise ratio (CNR) and lesion detectability index (d') were compared between the standard protocol and ATPS examinations. CTDIvol was reduced in all routine pitch ATPS examinations, with dose reductions of 27-52 % in CTA mode (P < 0.0001), 15-33 % in contrast-enhanced mode (P = 0.0003) and 8-14 % in non-contrast mode (P = 0.03). Iodine and soft tissue insert CNR and d' were improved or maintained in all ATPS examinations. kVp and dose were reduced in 25 % of high pitch ATPS examinations and in none of the full phantom examinations obtained after a single full phantom localizer. ATPS reduces radiation dose while maintaining image quality and lesion detectability in routine pitch paediatric abdominopelvic CT and CTA, but technical factors such as pitch and imaging range must be considered to optimize ATPS benefits. ATPS automatically individualizes CT scan technique for each patient. ATPS lowers radiation dose in routine pitch pediatric abdominopelvic CT and CTA. There is no loss of image quality or lesion detectability with ATPS. Pitch and scan range impact the effectiveness of ATPS dose reduction.

Automated Tube Potential Selection as a Method of Dose Reduction for CT of the Neck: First Clinical Results.

The objective of our study was to investigate whether the use of a software-based automated tube potential selection (ATPS) CT neck protocol can result in radiation dose reduction as compared with a set 120-kV protocol without a statistically significant reduction in image quality. Three hundred sixty-four patients (median age, 52 years) underwent CT of the neck. Group 1 (n = 320) underwent CT with ATPS with 80, 100, or 120 kV. Group 2 (n = 44) was examined with the standard CT protocol at 120 kV. Attenuation, image background noise, signal-to-noise ratio (SNR), dose-length product (DLP), volume CT dose index (CTDIvol), body mass index (BMI [weight in kilograms divided by the square of height in meters]), and subjective image quality (5-point Likert scale, two readers in consensus) were analyzed. A tube potential of 100 kV was selected in 279 patients, 120 kV in 40 patients, and 80 kV in one patient of the ATPS group. A significant correlation was found for selected tube potential and BMI (80 kV, BMI = 20.4; 100 kV, mean BMI = 24.2; 120 kV, BMI = 28.6; r = 0.28, p < 0.01). The average radiation dose was significantly lower with ATPS activated than with the standard protocol (mean DLP, 259 vs 350 mGy × cm, respectively). Background noise did not differ between groups 1 and 2 at the levels of the mandibular angle and the upper mediastinum; however, attenuation and SNR increased significantly with lower tube potential settings. Subjective image quality did not suffer (mean image quality score: ATPS protocol vs standard protocol, 4.56 vs 4.61, respectively; p > 0.05) with good interobserver agreement (κ > 0.56). ATPS allows significant dose savings for CT of the neck compared with a standard protocol that uses a fixed 120-kV setting without a statistically significant reduction in image quality.

Evaluation of the use of automatic exposure control and automatic tube potential selection in low-dose cerebrospinal fluid shunt head CT.

Cerebrospinal fluid shunts are primarily used for the treatment of hydrocephalus. Shunt complications may necessitate multiple non-contrast head CT scans resulting in potentially high levels of radiation dose starting at an early age. A new head CT protocol using automatic exposure control and automated tube potential selection has been implemented at our institution to reduce radiation exposure. The purpose of this study was to evaluate the reduction in radiation dose achieved by this protocol compared with a protocol with fixed parameters. A retrospective sample of 60 non-contrast head CT scans assessing for cerebrospinal fluid shunt malfunction was identified, 30 of which were performed with each protocol. The radiation doses of the two protocols were compared using the volume CT dose index and dose length product. The diagnostic acceptability and quality of each scan were evaluated by three independent readers. The new protocol lowered the average volume CT dose index from 15.2 to 9.2mGy representing a 39% reduction (P < 0.01; 95% CI 35-44%) and lowered the dose length product from 259.5 to 151.2mGy/cm representing a 42% reduction (P < 0.01; 95% CI 34-50%). The new protocol produced diagnostically acceptable scans with comparable image quality to the fixed parameter protocol. A pediatric shunt non-contrast head CT protocol using automatic exposure control and automated tube potential selection reduced patient radiation dose compared with a fixed parameter protocol while producing diagnostic images of comparable quality.

Coronary CTA using scout-based automated tube potential and current selection algorithm, with breast displacement results in lower radiation exposure in females compared to males.

To evaluate the effect of automatic tube potential selection and automatic exposure control combined with female breast displacement during coronary computed tomography angiography (CCTA) on radiation exposure in women versus men of the same body size. Consecutive clinical exams between January 2012 and July 2013 at an academic medical center were retrospectively analyzed. All examinations were performed using ECG-gating, automated tube potential, and tube current selection algorithm (APS-AEC) with breast displacement in females. Cohorts were stratified by sex and standard World Health Organization body mass index (BMI) ranges. CT dose index volume (CTDIvol), dose length product (DLP) median effective dose (ED), and size specific dose estimate (SSDE) were recorded. Univariable and multivariable regression analyses were performed to evaluate the effect of gender on radiation exposure per BMI. A total of 726 exams were included, 343 (47%) were females; mean BMI was similar by gender (28.6±6.9 kg/m(2) females vs. 29.2±6.3 kg/m(2) males; P=0.168). Median ED was 2.3 mSv (1.4-5.2) for females and 3.6 (2.5-5.9) for males (P<0.001). Females were exposed to less radiation by a difference in median ED of -1.3 mSv, CTDIvol -4.1 mGy, and SSDE -6.8 mGy (all P<0.001). After adjusting for BMI, patient characteristics, and gating mode, females exposure was lower by a median ED of -0.7 mSv, CTDIvol -2.3 mGy, and SSDE -3.15 mGy, respectively (all P<0.01). We observed a difference in radiation exposure to patients undergoing CCTA with the combined use of AEC-APS and breast displacement in female patients as compared to their BMI-matched male counterparts, with female patients receiving one third less exposure.

Image quality and required radiation dose for coronary computed tomography angiography using an automatic tube potential selection technique.

To investigate the image quality and the minimum required radiation dose for automatic tube potential selection (ATPS) in dual-source computed tomography (DSCT) coronary computed tomography angiography (CCTA). Three hundred twenty-five consecutive patients (153 men and 172 women) undergoing CCTA were assigned to either the ATPS group (n=172) or the control group (n=153); the control group underwent imaging at a constant current of 120kV. All patients were scanned in either prospectively ECG-triggered high-pitch helical mode or sequential mode. The subjective image quality score, attenuation, image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), volume CT dose index (CTDIvol), and effective dose (ED) were compared between the two groups with the Student t test or Mann-Whitney U test. The subjective image quality score was not significantly different between the two groups. Imaging noise and attenuation were both significantly higher in the ATPS group than in the control group (imaging noise: 25.6±7.6 versus 15.8±4.0HU, P<0.001; attenuation: 559.6±142.0 versus 412.5±64.3HU, P<0.001). SNR and CNR were significantly lower in the ATPS group than in the control group (SNR: 23.21±7.40 versus 27.71±8.25, P<0.001; CNR: 27.81±8.44 versus 33.94±9.69, P<0.001). ED was significantly lower in the ATPS group than in the control group (ED: 1.25±1.24 versus 2.19±1.77mSv, P<0.001). For both groups, ED was significantly lower in the high-pitch mode than in the sequential mode. The use of ATPS for CCTA significantly reduced the radiation dose while maintaining image quality.

Feasibility of a radiation dose conserving CT protocol for myocardial function assessment.

Assessment of myocardial function can be performed at higher noise levels than necessary for coronary arterial evaluation. We evaluated image quality and radiation exposure of a dose-conserving function-only acquisition vs retrospectively electrocardiogram(ECG)-gated coronary CTA with automatic tube current modulation. Of 26 patients who underwent clinically indicated coronary CTA for coronary and function evaluation, 13 (Group I) underwent prospectively ECG-triggered coronary CTA, followed by low-dose retrospectively ECG-gated scan for function (128-slice dual-source, 80 kVp; reference tube current, 100 mA; 8-mm-thick multiplanar reformatted reconstructions) performed either immediately (n = 6) or after 5- to 10-min delay for infarct assessment (n = 7). 13 corresponding controls (Group II) underwent retrospectively ECG-gated protocols (automatic tube potential selection with CARE kV/CARE Dose 4D; Siemens Healthcare, Forchheim, Germany) with aggressive dose modulation. Image quality assessment was performed on the six Group I subjects who underwent early post-contrast dedicated function scan and corresponding controls. Radiation exposure was based on dose-length product. Contrast-to-noise ratio (CNR) was preserved throughout the cardiac cycle in Group I and varied according to dose modulation in Group II. Visual image quality indices were similar during end systole but were better in Group II at end diastole. Although the total radiation exposure was equivalent in Group I and Group II (284 vs 280 mGy cm), the median radiation exposure associated with only the dedicated function scan was 138 mGy cm (interquartile range, 116-203 mGy cm). A low-dose retrospective ECG-gated protocol permits assessment of myocardial function at a median radiation exposure of 138 mGy cm and offers more consistent multiphase CNR vs traditional ECG-modulation protocols. This is useful for pure functional evaluation or as an adjunct to single-phase scan modes. Radiation exposure can be limited with a tailored myocardial function CT protocol while maintaining preserved images.

SU‐E‐I‐89: Assessment of CT Radiation Dose and Image Quality for An Automated Tube Potential Selection Algorithm Using Pediatric Anthropomorphic and ACR Phantoms

Purpose:To assess the impact of General Electrics automated tube potential algorithm, kV assist (kVa) on radiation dose and image quality, with an emphasis on optimizing protocols based on noise texture.Methods:Radiation dose was assessed by inserting optically stimulated luminescence dosimeters (OSLs) throughout the body of a pediatric anthropomorphic phantom (CIRS). The baseline protocol was: 120 kVp, 80 mA, 0.7s rotation time. Image quality was assessed by calculating the contrast to noise ratio (CNR) and noise power spectrum (NPS) from the ACR CT accreditation phantom. CNRs were calculated according to the steps described in ACR CT phantom testing document. NPS was determined by taking the 3D FFT of the uniformity section of the ACR phantom. NPS and CNR were evaluated with and without kVa and for all available adaptive iterative statistical reconstruction (ASiR) settings, ranging from 0 to 100%. Each NPS was also evaluated for its peak frequency difference (PFD) with respect to the baseline protocol.Results:For the baseline protocol, CNR was found to decrease from 0.460 ± 0.182 to 0.420 ± 0.057 when kVa was activated. When compared against the baseline protocol, the PFD at ASiR of 40% yielded a decrease in noise magnitude as realized by the increase in CNR = 0.620 ± 0.040. The liver dose decreased by 30% with kVa activation.Conclusion:Application of kVa reduces the liver dose up to 30%. However, reduction in image quality for abdominal scans occurs when using the automated tube voltage selection feature at the baseline protocol. As demonstrated by the CNR and NPS analysis, the texture and magnitude of the noise in reconstructed images at ASiR 40% was found to be the same as our baseline images. We have demonstrated that 30% dose reduction is possible when using 40% ASiR with kVa in pediatric patients.

SU‐E‐I‐81: Assessment of CT Radiation Dose and Image Quality for An Automated Tube Potential Selection Algorithm Using Adult Anthropomorphic and ACR Phantoms

Purpose:To assess the impact of General Electrics (GE) automated tube potential algorithm, kV assist (kVa) on radiation dose and image quality, with an emphasis on optimizing protocols based on noise texture.Methods:Radiation dose was assessed by inserting optically stimulated luminescence dosimeters (OSLs) throughout the body of an adult anthropomorphic phantom (CIRS). The baseline protocol was: 120 kVp, Auto mA (180 to 380 mA), noise index (NI) = 14, adaptive iterative statistical reconstruction (ASiR) of 20%, 0.8s rotation time. Image quality was evaluated by calculating the contrast to noise ratio (CNR) and noise power spectrum (NPS) from the ACR CT accreditation phantom. CNRs were calculated according to the steps described in ACR CT phantom testing document. NPS was determined by taking the 3D FFT of the uniformity section of the ACR phantom. NPS and CNR were evaluated with and without kVa and for all available adaptive iterative statistical reconstruction (ASiR) settings, ranging from 0 to 100%. Each NPS was also evaluated for its peak frequency difference (PFD) with respect to the baseline protocol.Results:The CNR for the adult male was found to decrease from CNR = 0.912 ± 0.045 for the baseline protocol without kVa to a CNR = 0.756 ± 0.049 with kVa activated. When compared against the baseline protocol, the PFD at ASiR of 40% yielded a decrease in noise magnitude as realized by the increase in CNR = 0.903 ± 0.023. The difference in the central liver dose with and without kVa was found to be 0.07%.Conclusion:Dose reduction was insignificant in the adult phantom. As determined by NPS analysis, ASiR of 40% produced images with similar noise texture to the baseline protocol. However, the CNR at ASiR of 40% with kVa fails to meet the current ACR CNR passing requirement of 1.0.

Standard chest CT using combined automated tube potential selection and iterative reconstruction: image quality and radiation dose reduction

ObjectiveTo evaluate the image quality and radiation dose reduction of chest computed tomography (CT) using combined automated tube potential selection (ATPS) and iterative reconstruction (IR). Materials and MethodsImage quality and radiation dose were compared between conventional contrast-enhanced chest CT using 120 kVp and filtered back projection (Protocol A) and CT using ATPS and IR (Protocol B) in 43 patients. ResultsThe effective radiation dose was 3.6±0.4 mSv for Protocol A and 2.2±0.6 mSv for Protocol B (mean dose reduction, 39.7%). Protocol B showed diagnostic image quality in all patients. ConclusionATPS and IR allows for radiation dose reduction while maintaining diagnostic image quality.