Autogenous Fibula Research Articles

Finite element analysis and biomechanical study of "sandwich" fixation in the treatment of elderly proximal humerus fractures.

Proximal humerus fractures (PHFs) are common in the elderly and usually involve defects in the medial column.The current standard for medial column reconstruction is a lateral locking plate (LLP) in combination with either an intramedullary fibula support or an autogenous fibula graft. However, autogenous fibula graft can lead to additional trauma for patients and allogeneic fibular graft can increase patients' economic burden and pose risks of infection and disease transmission. The primary objective of this study was to introduce and assess a novel "Sandwich" fixation technique and compare its biomechanical properties to the traditional fixation methods for PHFs. In this study, we established finite element models of two different internal fixation methods: LLP-intramedullary reconstruction plate with bone cement (LLP-IRPBC) and LLP-intramedullary fibula segment (LLP-IFS). The biomechanical properties of the two fixation methods were evaluated by applying axial, adduction, abduction, torsional loads and screw extraction tests to the models. These FEA results were subsequently validated through a series of biomechanical experiments. Under various loading conditions such as axial, adduction, abduction, and rotation, the LLP-IRPBC group consistently demonstrated higher structural stiffness and less displacement compared to the LLP-IFS group, regardless of whether the bone was in a normal (Nor) or osteoporotic (Ost) state. Under axial, abduction and torsional loads, the maximum stress on LLPs of LLP-IRPBC group was lower than that of LLP-IFS group, while under adduction load, the maximum stress on LLPs of LLP-IRPBC group was higher than that of LLP-IFS group under Ost condition, and almost the same under Nor condition. The screw-pulling force in the LLP-IRPBC group was 1.85 times greater than that of the LLP-IFS group in Nor conditions and 1.36 times greater in Ost conditions. Importantly, the results of the biomechanical experiments closely mirrored those obtained through FEA, confirming the accuracy and reliability of FEA. The novel "Sandwich" fixation technique appears to offer stable medial support and rotational stability while significantly enhancing the strength of the fixation screws. This innovative approach represents a promising strategy for clinical treatment of PHFs.

Autogenous fibula graft and cannulated screw fixation to cephalic cut out after DHS fixation: a retrospective study

BackgroundThis study aimed to explore the effect of the treatment through autologous fibula graft and hollow needle fixation to treat femoral head cutting after dynamic hip screw (DHS) fixation.MethodsA total of 41 patients were admitted to the department of orthopedic trauma and received DHS fixation. Preoperative and postoperative harris score of hip function, limb shortening length and collodiaphysial angle between operation group (n = 11) and non-operation group (n = 13) were compared.ResultsThere was no difference between the two groups before surgery (P > 0.05). There was a difference between the preoperative and postoperative in the operation group (P < 0.05). The excellent and good rate of the hip function score in patients 6 months after the operation was 55.6%. In the operation group, the hip function score increased after surgery (P < 0.001). Except for two groups of patients before operation, there was a difference in the limb shortening length and collodiaphysial angle between the operation group and non-operation group in other time points after surgery (P < 0.001).ConclusionThe application of the autogenous fibula graft and hollow nail fixation was effective in treating femoral head cutting after DHS fixation, and patients’ subjective evaluation and objective indicators’ outcomes of follow up were satisfactory, which was worthy of clinical application.

How to optimize the therapeutic effect of free autogenous fibula graft and wrist arthroplasty for giant cell tumors of distal radius?

The purpose of this study is to retrospectively analyze the clinical efficacy of free fibula autograft and wrist arthroplasty in the treatment of giant cell tumors (GCT) of distal radius. We retrospectively reviewed 26 patients with GCT of distal radius who underwent free autogenous fibula graft and wrist arthroplasty for repairing residual defect after en-block resection. The length of the fibula graft was 8.2 cm (6-10 cm). Postoperative follow-up regularly for an mean of 66.9 months. Bone healing was assessed by radiographs, pain was assessed by Visual Analog Scale (VAS) score and limb function was evaluated by Musculoskeletal Tumor Society (MSTS) score and disabilites of the arm, shoulder and hand (DASH) score. The range of motion (ROM) of wrist and grip strength were also evaluated. There were four males and 22 females with an mean age of 36.7 years (19-60 years); the mean length of lesions was 4.8 cm (2.3-6.6 cm); 21 primary cases and five recurrent cases; eight cases of Campanacci Grade II, 18 cases of Grade III. We had no postoperative lung metastasis and only one case had a local recurrence, three cases (11%) with subluxation of lower ulnoradial joints and five cases (19%) showed narrowing of wrist joint space. The mean postoperative VAS pain score was 0.7 ± 0.7 and grip strength retained 71% of the normal hand, MSTS score was 27.7 ± 1.1 and DASH score was 9.0 ± 3.7. The ROM of the involved wrist only slightly restricted and no donor complications. Postoperative wrist joint function was significantly improved. Strict surgical resection boundary and solid reconstruction of wrist joint capsule are the key to achieving excellent oncological prognosis and function of distal radius GCT.

LONG TERM EVALUATION OF VASCULARIZED FIBULAR GRAFT AS TREATMENT AFTER RESECTION OF GIANT CELL TUMOR (GCT) AT RIGHT PROXIMAL HUMERUS: A CASE REPORT

Giant cell tumors are locally aggressive tumors with high rate of recurrence. Recurrences of GCT in autogenous fibular grafts have been rarely reported and pathological fractures through such grafts are even rarer. Wide excision is the management of choice, but this creates a defect at bone. The preferred modalities for the defect reconstruction include vascularized/non-vascularized bone graft, osteoarticular allografts and custom-made prosthesis. We present our experience with wide resection and vascularized autogenous fibula grafting for GCT of proximal humerus.

Pott's Disease in a 2-Year-Old Child Treated by Decompression and Anterior-Posterior Instrumented Fusion.

Introduction. Paraplegia and kyphotic deformity are two major disease-related problems of spinal tuberculosis, especially in the early age disease. In this study a 2-year-old boy who underwent surgical decompression, correction, and 360° instrumented fusion via simultaneous anterior-posterior technique for Pott's disease was reported. Case Report. A 2-year-and-9-month-old boy presented with severe back pain and paraparesis of one-month duration. Thoracic magnetic resonance imaging demonstrated destruction with a large paraspinal abscess involving T5-T6-T7 levels, compressing the spinal cord. The paraspinal abscess drained and three-level corpectomy was performed at T5-6-7 with transthoracic approach. Anterior instrumentation and fusion was performed with structural 1 autogenous fibula and rib graft using screw-rod system. In prone position pedicle screws were inserted at T4 and T8 levels and rods were placed. Six months after surgery, there was no weakness or paraparesis and no correction loss at the end of follow-up period. Discussion. In cases of vertebral osteomyelitis with severe anterior column destruction in the very early child ages the use of anterior structural grafts and instrumentation in combination with posterior instrumentation is safe and effective in maintenance of the correction achieved and allows efficient stabilization and early mobilization.

En bloc excision and autogenous fibular reconstruction for aggressive giant cell tumor of distal radius: a report of 12 cases and review of literature

IntroductionGiant cell tumor (GCT) of distal radius follows a comparatively aggressive behaviour. Wide excision is the management of choice, but this creates a defect at the distal end of radius. The preffered modalities for reconstruction of such a defect include vascularized/non-vascularized bone graft, osteoarticular allografts and custom-made prosthesis. We here present our experience with wide resection and non-vascularised autogenous fibula grafting for GCT of distal radius.Materials and methodsTwelve patients with a mean age of 34.7 years (21-43 years) with Campanacci Grade II/III GCT of distal radius were managed with wide excision of tumor and reconstruction with ipsilateral nonvascularised fibula, fixed with small fragment plate to the remnant of the radius. Primary autogenous iliac crest grafting was done at the fibuloradial junction in all the patients.ResultsMean follow up period was 5.8 years (8.2-3.7 years). Average time for union at fibuloradial junction was 33 weeks (14-69 weeks). Mean grip strength of involved side was 71% (42-86%). The average range of movements were 52° forearm supination, 37° forearm pronation, 42° of wrist palmerflexion and 31° of wrist dorsiflexion with combined movements of 162°. Overall revised musculoskeletal tumor society (MSTS) score averaged 91.38% (76.67-93.33%) with five excellent, four good and three satisfactory results. There were no cases with graft related complications or deep infections, 3 cases with wrist subluxation, 2 cases with non union (which subsequently united with bone grafting) and 1 case of tumor recurrence.ConclusionAlthough complication rate is high, autogenous non-vascularised fibular autograft reconstruction of distal radius can be considered as a reasonable option after en bloc excision of Grade II/III GCT.

Donor-site complications of autogenous nonvascularized fibula strut graft harvest for anterior cervical corpectomy and fusion surgery: experience with 163 consecutive cases

Background context The fibula is a source of bone graft for reconstruction of the appendicular and axial skeleton. Purpose The aim of this study is to determine donor-site complications and morbidity in a large series of patients who underwent autogenous fibula harvesting for anterior cervical corpectomy and fusion (ACCF) surgery. Study design/setting Retrospective review (Level III). Patient sample One hundred sixty-three patients over an eight-year period who underwent ACCF with autogenous fibula. Outcome measures Donor site complications (such as infection, cellulitis, pain, damage to the superficial peroneal nerve, ankle instability, tibial stress fracture, and so forth), treatment, and final outcome were determined from patient records. Methods Retrospective study of patients who underwent ACCF with autogenous nonvascularized fibula strut graft over an eight-year period (from 1995 to 2002) was conducted. Donor site complications (such as infection, cellulitis, pain, damage to the superficial peroneal nerve, ankle instability, tibial stress fracture, and so forth), treatment, and final outcome were determined from patient records. Results One hundred sixty-three patients underwent ACCF with autogenous fibula graft during the study period. The most common short-term complication (lasting <3 months) was incisional pain, present in 86 of 163 patients (53%). Incisional pain lasted longer than 3 months in 25 of 163 patients (15%) but resolved in all but two patients by 24 months. Two patients (1.2%) developed superficial peroneal neuromas. Five patients (3%) developed tibial stress fractures. Two patients (1.2%) developed ankle instability. Fifteen (9%) patients developed cellulitis that resolved in all patients after a short course of oral antibiotics, with one additional patient developing a deep infection requiring surgical debridement and intravenous antibiotics. Conclusions Although autogenous fibula is an excellent graft for multilevel ACCF reconstruction, surgeons should carefully consider the associated morbidity of fibular harvest before surgery. In this series, most complications were of short duration. However, nine patients with long-term complications required five additional surgical procedures. Therefore, patients who are scheduled to undergo autogenous fibula harvest should be advised about these potential complications.

Settling of Fibula Strut Grafts Following Multilevel Anterior Cervical Corpectomy

This is a retrospective study of settling of fibula strut grafts used for anterior cervical reconstruction. To measure settling and kyphotic angulation of uninstrumented fibula strut graft reconstruction for two- and three-level cervical corpectomy procedures. Clinical experience indicates that some settling of anterior fibula strut grafts used in anterior cervical reconstruction will occur. The amount of settling and subsequent kyphosis using this technique has not been documented in the literature. Twenty-six patients having had nonvascularized autogenous fibula strut grafting without instrumentation following a two- or three-level corpectomy were studied. Baseline radiographic measurements of height and angulation on postoperative radiographs before hospital discharge were compared with measurements performed at least 2 years after surgery. Clinical follow-up was also available on all patients. The average settling manifested by loss of height across the fused segments was 6.7 mm (standard deviation, 5.71 mm). The average change in angulation was 2.5 degrees into kyphosis (standard deviation, 6.09 degrees ). Loss of height and angulation were not statistically different for two- versus three-level corpectomy patients. Pain outcomes did not correlate with the amount of settling or angulation. Some settling of autogenous fibula strut grafting without instrumentation can be expected. These findings did not correlate with residual postoperative axial neck pain.

Osteomyelitis of Multiple Lumbar Vertebrae Associated with Infected Aortic Aneurysm: A Case Report

A 73-year-old male patient presented with a pulsating abdominal mass and intractable low back pain for several days. Magnetic resonance imaging revealed an infected abdominal aortic aneurysm invading the second, third, and fourth lumbar vertebrae. He underwent radical debridement of the infected aneurysm with reconstruction using vascular bypass, partial corpectomy of the L2 to L4 vertebrae, anterior reconstruction with autogenous fibular shaft, and posterior instrumentation with posterolateral fusion. Culture of the necrotic tissues grew oxacillin-resistant Staphylococcus aureus. He received intravenous vancomycin infusion for 4 weeks and oral ciprofloxacin for 6 months postoperatively. After a 15-month follow-up, no apparent signs of further infection were noted. C-reactive protein and erythrocyte sedimentation rate returned to normal during follow-up. No neurologic symptoms other than mild low back soreness were noted. The stability of the lumbar spine was maintained using long segment reconstruction with autogenous fibula shaft and posterior instrumentation along with posterolateral fusion. Infected aortic aneurysm with vertebral osteomyelitis is a rare clinical entity. Prompt diagnosis and adequate treatment are essential.

Reneration of the donor side after autogenous fibula transplantation in 53 patients

We determined the degree of fibular regeneration at the donor site, using radiographs and dual x-ray absorptiometry, in 53 patients who underwent autogenous nonvascularized fibular transplantation for tumor reconstruction in long bones (mean follow-up 15 (3–26) years). Logistic regression was used to determine whether gender, age at transplantation, time since transplantation, bone mineral density (BMD), and length of the graft were associated with fibular regeneration.26 patients had spontaneous complete bone regeneration. Younger age at transplant was the only predictor of fibular regeneration. In predicting fibular regeneration, sensitivity was 96% and specificity 74%, using 15 years of age as a cut-off. In the long-term follow-up, we found only gradual changes in the BMD and the values ranged from 24% to 217%. We found no correlations of bone mineral density with age, gender, length of the graft, or time since transplantation.

Regeneration of the donor side after autogenous fibula transplantation in 53 patients: evaluation by dual x-ray absorptiometry.

We determined the degree of fibular regeneration at the donor site, using radiographs and dual x-ray absorptiometry, in 53 patients who underwent autogenous nonvascularized fibular transplantation for tumor reconstruction in long bones (mean follow-up 15 (3-26) years). Logistic regression was used to determine whether gender, age at transplantation, time since transplantation, bone mineral density (BMD), and length of the graft were associated with fibular regeneration. 26 patients had spontaneous complete bone regeneration. Younger age at transplant was the only predictor of fibular regeneration. In predicting fibular regeneration, sensitivity was 96% and specificity 74%, using 15 years of age as a cut-off. In the long-term follow-up, we found only gradual changes in the BMD and the values ranged from 24% to 217%. We found no correlations of bone mineral density with age, gender, length of the graft, or time since transplantation.

The arthrodesis rate in multilevel anterior cervical fusions using autogenous fibula.

This study was a roentgenographic review of 145 patients who underwent multilevel anterior cervical arthrodesis using autogenous fibula. To determine the arthrodesis rate in multilevel cervical fusions using autogenous fibula. Previous studies have shown an unacceptably high rate of nonunions with multilevel anterior cervical arthrodesis. However, this has not been the clinical experience of the author's group. Lateral roentgenograms taken a minimum of 2 years after surgery were reviewed independently by two radiologists. If either radiologist questioned any fusion level, the final decision was made on the basis of flexion-extension roentgenograms. An overall union rate of 90% and 94% per patient was found for each level of attempted fusion. A solid arthrodesis was achieved in 93% of the patients with two-level fusions, and 84% of the three-level fusions were solid. The difference was not statistically significant. Autogenous fibula used as a strut graft results in an acceptable union rate for multilevel anterior cervical arthrodesis.

Surgical reconstruction of fibrous dysplasia of bone in long-term follow-up

To examine how different operative measures influence the surgical outcome in patients with fibrous dysplasia of bone. 118 dysplastic fibrous lesions of bone were surgically treated and reviewed in 70 patients between 1983 to 1993 (eleven years) with a median follow-up of six and a half years. Surgery consisted of intralesional curettage in 93 and marginal en bloc resection in 25 lesions. Bony defects were reconstructed with autogenous iliac crest graft in 55 lesions, with autogenous fibula graft in 9, with homologous bone chips in 28, and 5 times with a homologous fibula graft from the bone bank. In 33 lesions the entire defect was filled with polymethylmethacrylate. Osteosynthesis was performed in 41 patients. Recurrences requiring surgical revision were observed in 26 of 74 primary lesions (= 35% overall recurrence rate) at a mean 123.6 weeks postoperatively. The most frequent primary and recurrence location was the proximal femur (85% revision rate). 69% of all recurrences occurred under the age of 20. After intralesional curettage the reoperation rate was 32% and after marginal resection 8%. After reconstruction with autogenous iliac crest graft recurrence rate was 36%, after autogenous fibula graft 55%, after homologous bone chips 18%, after polymethylmethacrylate 9% and allograft fibula reconstruction showed no recurrences. A combined stable osteosynthesis bridging the fibrous osseous defect significantly reduced the revision rate to 3% (p = 0.01). Intralesional curettage and reconstruction with autogenous iliac crest graft in fibrous dysplasia of bone leads to a high recurrence rate. Reconstruction with cortical grafts or bone chips from the bone bank, if necessary in combination with a durable osteosynthesis in mechanically demanding locations, or solely bone cement in mechanically less demanding areas, reduces the revision rate in patients with monoostotic and polyostotic fibrous dysplasia.

Ｂａｒｒ´ｅ‐Ｌｉ´ｅｏｕ徴候を伴った頚椎カリエスの１例

Tuberculosis of the cervical spine is uncommon to arise in the whole apine. We report a case of tuberculous cervical spondylitis with Barre-Lieou syndrome.The case was a 61 year old female, who complained of mild muscle weakness and strong dizziness at motion, headache, nausea, so called Barre-Lieou syndrome. MRI showed rim enhancement of the retropharyngeal soft tissue and peridural abscess. We therefore performed the operation of curretage and anterior spinal body fusion by use of autogenous fibula bone, adding the chemotherapy of INH, RFP and SM. She gradually recovered from Barre-Lieou syndrome.The origin of Barre-Lieou syndrome in this case was unsidered the source of the irritation of the vertebral nerve by tuberculous abscess.

The surgical anatomy of the principal nutrient vessel of the tibia.

Large segmental long-bone defects deserve consideration for reconstruction by vascularized, straight, high-density cortical bone grafts of comparable diameter. If available, the tibial diaphysis would be an option superior to the fibula, since the latter has known limitations when a large size discrepancy exists at the recipient site. However, the former choice is unrealistic except in the most unusual circumstances, since the tibia is a nonexpandable bone required for weight bearing. In anticipation of just such a unique opportunity, we have investigated the surgical anatomy of the principal nutrient vessel of the shaft of the tibia in 53 fresh lower limb specimens. Classical descriptions of the pertinent vascular anatomy of the tibial shaft are inadequate, since the origin of its principal nutrient vessel actually may be from the popliteal bifurcation or anterior or posterior tibial vessels. In every dissection at least a single artery and vein of large caliber (both exceeding 1.5 mm in diameter in 85 percent of cadavers) were discovered entering a nutrient foramen, usually at the upper third of the tibia. Lead oxide injection studies of the nutrient artery alone in nine cadavers demonstrated no contiguous muscle or cutaneous communications. The large size of these nutrient vessels would simplify ipsilateral pedicled transfers of an autologous tibial shaft as well as facilitate microanastomoses for its distant transfer to other humeral, femoral, or contralateral tibial defects as in a salvage replantation. Once immunologic barriers have been conquered, these data should have even greater practical clinical significance for the use of vascularized tibial allografts for substitution in lieu of autogenous fibula or other conventional bone donor sites.

Treatment of Benign Lesions of the Femoral Head and Neck

Benign lesions of the proximal femur usually weaken the supporting framework in the femoral neck. Of seven patients aged 11 through 26 years with the diagnosis of fibrous dysplasia (four), aneurysmal bone cyst (two), and simple bone cyst (one), six were treated with curretage and an autogenous fibula strut graft in conjunction with a sliding hip screw. One patient was treated with only the curretage and strut graft. The functional results were excellent (five), good (one), and fair (one), with no local recurrence. In treating fibrous dysplasia, dysplastic bone should be supplemented with grafts of cortical bone. This construct provides increased strength and prevents deformity and fracture, but it does not eradicate the disease. Internal fixation promotes union of the cortical graft to the host cancellous bone. The sliding screw stabilizes the bone and eliminates the need for plaster casts.

Aneurysmal Bone Cyst of the Sternum

A very rare case of aneurysmal bone cyst of the sternum is described. Aneurysmal bone cyst is a tumorlike bone lesion occumng commonly in the metaphysis of long bones and in the vertebrae. This report is one of the very few cases in the literature of aneurysmal bone cyst of the sternum. Total resection of the tumor and reconstruction of the sternal defect using autogenous fibula are presented