Atypical Face Processing Research Articles

Reduced gamma oscillation during visual processing of the mother's face in children with autism spectrum disorder: A pilot study.

This study aimed to investigate gamma oscillations related to face processing of children with autism spectrum disorders and typically developed children using magnetoencephalography. We developed stimuli that included naturalistic real-time eye-gaze situations between participants and their mothers. Eighteen young children with autism spectrum disorders (62-97 months) and 24 typically developed children (61-79 months) were included. The magnetoencephalography data were analyzed in the bilateral banks of the superior temporal sulcus, fusiform gyrus, and pericalcarine cortex for frequency ranges 30-59 and 61-90 Hz. The gamma oscillation normalized values were calculated to compare the face condition (children gazing at mother's face) and control measurements (baseline) using the following formula: (face - control)/(face + control). The results revealed significant differences in gamma oscillation normalized values in the low gamma band (30-59 Hz) in the right banks of the superior temporal sulcus, right fusiform gyrus, and right pericalcarine cortex between children with autism spectrum disorders and typically developed children. Furthermore, there were significant differences in gamma oscillation normalized values in the high gamma band (61-90 Hz) in the right banks of the superior temporal sulcus, bilateral fusiform gyrus, and bilateral pericalcarine cortex between the groups. This report is the first magnetoencephalography study revealing atypical face processing in young children with autism spectrum disorders using relevant stimuli between participants and their mothers. Our naturalistic paradigm provides a useful assessment of social communication traits and a valuable insight into the underlying neural mechanisms in children with autism spectrum disorders.

Understanding emotional language through events and words in people with Williams syndrome

ABSTRACT Previous studies have mainly examined emotion recognition through face processing in individuals with Williams syndrome (WS). Contextual integration is an automatic and basic comprehension ability emerged from distinct modalities. This ability requires sensation to global configuration and local elements. However, neurodevelopmental disorders are characterized by local-focusing and global-ignoring in visuospatial perception. This causes cognitive atypicality as compared to typical development, including atypical face processing and emotion recognition. These impairments might result in deficits in theory of mind and social cognition. People with WS demonstrate impaired false-belief attribution, which was reported to be improved with emotional cues. Yet, no previous study has examined knowledge of emotional language in people with WS, which might be one of the factors affecting the development of the theory of mind in people with WS. In the present study, we examined knowledge of emotional language in people with WS by testing three emotions: positive, negative, and neutral. Participants were asked to press buttons indexing emotions in reaction to auditory targets. In the emotional event study, people with WS demonstrated responses to positive events in the normal range, delayed responses to negative events, and deviant responses to neutral events. In the emotion word study, people with WS showed the lowest accuracy and longest reaction times for neutral words. These findings indicated asymmetrical and atypical knowledge of emotional language in people with WS, confirming that knowledge of emotional expressions influences the development of the theory of mind and social cognition.

Characterizing the neural signature of face processing in Williams syndrome via multivariate pattern analysis and event related potentials

Face recognition ability is often reported to be a relative strength in Williams syndrome (WS). Yet methodological issues associated with the supporting research, and evidence that atypical face processing mechanisms may drive outcomes ‘in the typical range’, challenge these simplistic characterisations of this important social ability. Detailed investigations of face processing abilities in WS both at a behavioural and neural level provide critical insights. Here, we behaviourally characterised face recognition ability in 18 individuals with WS comparatively to typically developing children and adult control groups. A subset of 11 participants with WS as well as chronologically age matched typical adults further took part in an EEG task where they were asked to attentively view a series of upright and inverted faces and houses. State-of-the-art multivariate pattern analysis (MVPA) was used alongside standard ERP analysis to obtain a detailed characterisation of the neural profile associated with 1) viewing faces as an overall category (by examining neural activity associated with upright faces and houses), and to 2) the canonical upright configuration of a face, critically associated with expertise in typical development and often linked with holistic processing (upright and inverted faces). Our results show that while face recognition ability is not on average at a chronological age-appropriate level in individuals with WS, it nonetheless appears to be a relative strength within their cognitive profile. Furthermore, all participants with WS revealed a differential pattern of neural activity to faces compared to objects, showing a distinct response to faces as a category, as well as a differential neural pattern for upright vs. inverted faces. Nonetheless, an atypical profile of face orientation classification was found in WS, suggesting that this group differs from typical individuals in their face processing mechanisms. Through this innovative application of MVPA, alongside the high temporal resolution of EEG, we provide important new insights into the neural processing of faces in WS.

Eye-gaze processing in the broader bipolar phenotype revealed by electrical neuroimaging

Previous studies have documented atypical brain responses to faces in individuals with bipolar disorder (BD) and in their relatives. In view of previous findings of atypical face processing in youths at risk for BD, the aim of this study was to examine whether BD patients and offspring would show differential activation in networks of the social brain when processing eye-gaze.Data from 18 euthymic BD patients and 18 offspring, as well as 36 age-matched healthy controls, were collected using a delayed face-matching paradigm, event related potentials and electrical neuroimaging methods.The P200 component, which is implicated in facial cues decoding, differentiated the BD groups from their age-matched controls. P200 source reconstruction indicates impairments conveyed by eye-contact in a network involved in experiencing others’ social intentions in BD patients (supplementary motor cortex, precentral gyrus, inferior parietal lobe), and the engagement of compensatory prefrontal mechanisms for modulating these functions in BD offspring. When viewing faces that had an averted gaze, BD patients and offspring showed a hypo-activation, compared to controls, particularly in regions involved in experiencing others’ feelings (post-central gyrus in BD patients / ventral premotor cortex in offspring). Therefore, the neural mechanism for decoding shifts in eye-gaze may be a familial characteristic of BD.

Reduced distractor interference in neurotypical adults with high expression of autistic traits irrespective of stimulus type.

Attention atypicality is evident in autism spectrum disorder (ASD) and its broader phenotype with previous studies suggesting that in some cases participants can be more efficient at ignoring distracting irrelevant information. However, it is not clear to what extent this improved filtering capacity is driven by perceptual atypicality, such as local bias or atypical face processing, which is also sometimes reported in these populations. For instance, better ability to ignore the global aspect of a display could stem from a local perceptual bias rather than from improved distractor inhibition. To test whether distractor suppression per se, is associated with high expression of autistic traits, in the present study a large cohort of neurotypical participants (n = 218), in whom expression of autistic traits was assessed, performed two nonspatial attention selection tasks with different categories of stimuli (global/local and face/scene). Importantly, both tasks involved a conflict with one aspect of the stimuli designated as the target and the other designated as the distractor. Across the two experiments adults with high autistic traits were overall, better able to ignore distractors than adults with low autistic traits, irrespective of the type of perceptual processing involved. These results support the notion that autistic tendencies are associated with increased attention filtering (at least when target and distractor remain constant) which is not dependent on perceptual biases. Thus, future work in the broader autism phenotype should explicitly consider the effect played by attention mechanisms in this population. Autism Res 2018, 11: 1345-1355. © 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: In the present study, we show that neurotypical adults with high autistic traits are better able to avoid distraction from conspicuous (but completely irrelevant) distractors when told in advance to do so. This ability is not affected by the type of visual input (for instance, whether the distractor is a face or whether small rather than large letters should be reported). This finding could be important in better understanding the way attention is utilized in Autism.

Atypical Processing of Gaze Cues and Faces Explains Comorbidity between Autism Spectrum Disorder (ASD) and Attention Deficit/Hyperactivity Disorder (ADHD)

This study investigated the neurobiological basis of comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). We compared children with ASD, ADHD or ADHD+ASD and typically developing controls (CTRL) on behavioural and electrophysiological correlates of gaze cue and face processing. We measured effects of ASD, ADHD and their interaction on the EDAN, an ERP marker of orienting visual attention towards a spatially cued location and the N170, a right-hemisphere lateralised ERP linked to face processing. We identified atypical gaze cue and face processing in children with ASD and ADHD+ASD compared with the ADHD and CTRL groups. The findings indicate a neurobiological basis for the presence of comorbid ASD symptoms in ADHD. Further research using larger samples is needed.

An Event-Related Potential Study on the Perception and the Recognition of Face, Facial Features, and Objects in Children With Autism Spectrum Disorders.

The study investigated whether children with autism spectrum disorders (ASD) showed atypical patterns of brain specialization for face processing, whether the response to familiar and unfamiliar faces, facial features, and objects were different from typically developing children. Event-related potentials were recorded in 5- to 8-year-old children (12 children with ASD, 12 typically developing children) using passive viewing paradigm. The fastest P1 latencies to faces and the largest P1 amplitudes to objects were observed in both participant groups. Both groups exhibited larger N170 response to faces and eyes, F(3, 66) = 46.94, p < .0001). However, earlier P1 and N170 latencies were found on left hemisphere in children with ASD, respectively, F(1, 83) = 4.32, p = .04; F(1, 83) = 6.73, p = .01, indicating an atypical face processing pattern. All children showed a significant effect of familiarity for objects and mouths, F(1, 71) = 33.97, p < .0001; F(1, 71 = 15.94, p = .0002. Children with ASD revealed smaller negative central to faces relative to typically developing children. Face processing abnormalities revealed in children with ASD very likely exist.

Causation model of autism: Audiovisual brain specialization in infancy competes with social brain networks

Earliest identifiable findings in autism indicate that the autistic brain develops differently from the typical brain in the first year of life, after a period of typical development. Twin studies suggest that autism has an environmental component contributing to causation. Increased availability of audiovisual (AV) materials and viewing practices of infants parallel the time frame of the rise in prevalence of autism spectrum disorder (ASD). Studies have shown an association between ASD and increased TV/cable screen exposure in infancy, suggesting AV exposure in infancy as a possible contributing cause of ASD.Infants are attracted to the saliency of AV materials, yet do not have the experience to recognize these stimuli as socially relevant. The authors present a developmental model of autism in which exposure to screen-based AV input in genetically susceptible infants stimulates specialization of non-social sensory processing in the brain. Through a process of neuroplasticity, the autistic infant develops the skills that are driven by the AV viewing. The AV developed neuronal pathways compete with preference for social processing, negatively affecting development of social brain pathways and causing global developmental delay. This model explains atypical face and speech processing, as well as preference for AV synchrony over biological motion in ASD. Neural hyper-connectivity, enlarged brain size and special abilities in visual, auditory and motion processing in ASD are also explained by the model. Positive effects of early intervention are predicted by the model. Researchers studying causation of autism have largely overlooked AV exposure in infancy as a potential contributing factor. The authors call for increased public awareness of the association between early screen viewing and ASD, and a concerted research effort to determine the extent of causal relationship.

Neural and behavioural responses to face-likeness of objects in adolescents with autism spectrum disorder

Numerous studies have revealed atypical face processing in autism spectrum disorders (ASD) characterized by social interaction and communication difficulties. This study investigated sensitivity to face-likeness in ASD. In Experiment 1, we found a strong positive correlation between the face-likeness ratings of non-face objects in the ASD (11–19 years old) and the typically developing (TD) group (9–21 years old). In Experiment 2 (the scalp-recorded event-related potential experiment), the participants of both groups (ASD, 12–19 years old; TD, 12–18 years old) exhibited an enhanced face-sensitive N170 amplitude to a face-like object. Whereas the TD adolescents showed an enhanced N170 during the face-likeness judgements, adolescents with ASD did not. Thus, both individuals with ASD and TD individuals have a perceptual and neural sensitivity to face-like features in objects. When required to process face-like features, a face-related brain system reacts more strongly in TD individuals but not in individuals with ASD.

Face-sensitive brain responses measured from a four-year-old child with a custom-sized child MEG system

BackgroundPrevious magnetoencephalography (MEG) studies have failed to find a facesensitive, brain response-M170 in children. If this is the case, this suggests that the developmental trajectory of the M170 is different from that of its electrical equivalent, the N170. We investigated the alternative possibility that the child M170 may not be detectable in conventional adult-sized MEG systems. New methodBrain responses to pictures of faces and well controlled stimuli were measured from the same four-year-old child with a custom child MEG system and an adult-sized MEG system. ResultsThe goodness of fit of the child's head was about the same over the occipital head surface in both systems, but was much worse over all other parts of the head surface in the adult MEG system compared to the child MEG system. The face-sensitive M170 was measured from the child in both MEG systems, but was larger in amplitude, clearer in morphology, and had a more accurate source localization when measured in the child MEG system. Comparison with existing methodThe custom-sized child MEG system is superior for measuring the face-sensitive M170 brain response in children than the conventional adult MEG system. ConclusionsThe present results show that the face-sensitive M170 brain response can be elicited in a four-year-old child. This provides new evidence for early maturation of face processing brain mechanisms in humans, and offers new opportunities for the study of neurodevelopmental disorders that show atypical face processing capabilities, such as autism spectrum disorder.

Single-Neuron Correlates of Atypical Face Processing in Autism

People with autism spectrum disorder (ASD) show abnormal processing of faces. A range of morphometric, histological, and neuroimaging studies suggest the hypothesis that this abnormality may be linked to the amygdala. We recorded data from single neurons within the amygdalae of two rare neurosurgical patients with ASD. While basic electrophysiological response parameters were normal, there were specific and striking abnormalities in how individual facial features drove neuronal response. Compared to control patients, a population of neurons in the two ASD patients responded significantly more to the mouth, but less to the eyes. Moreover, we found a second class of face-responsive neurons for which responses to faces appeared normal. The findings confirm the amygdala's pivotal role in abnormal face processing by people with ASD at the cellular level and suggest that dysfunction may be traced to a specific subpopulation of neurons with altered selectivity for the features of faces.

Atypical Face Processing in Children with Tuberous Sclerosis Complex (P02.100)

Atypical Face Processing in Children with Tuberous Sclerosis Complex (P02.100)

It's all in the eyes: subcortical and cortical activation during grotesqueness perception in autism.

Atypical face processing plays a key role in social interaction difficulties encountered by individuals with autism. In the current fMRI study, the Thatcher illusion was used to investigate several aspects of face processing in 20 young adults with high-functioning autism spectrum disorder (ASD) and 20 matched neurotypical controls. “Thatcherized” stimuli were modified at either the eyes or the mouth and participants discriminated between pairs of faces while cued to attend to either of these features in upright and inverted orientation. Behavioral data confirmed sensitivity to the illusion and intact configural processing in ASD. Directing attention towards the eyes vs. the mouth in upright faces in ASD led to (1) improved discrimination accuracy; (2) increased activation in areas involved in social and emotional processing; (3) increased activation in subcortical face-processing areas. Our findings show that when explicitly cued to attend to the eyes, activation of cortical areas involved in face processing, including its social and emotional aspects, can be enhanced in autism. This suggests that impairments in face processing in autism may be caused by a deficit in social attention, and that giving specific cues to attend to the eye-region when performing behavioral therapies aimed at improving social skills may result in a better outcome.

Atypical Face Processing in Children With Tuberous Sclerosis Complex

There is a high incidence of autism in tuberous sclerosis complex. Given the evidence of impaired face processing in autism, the authors sought to investigate electrophysiological markers of face processing in children with tuberous sclerosis complex. The authors studied 19 children with tuberous sclerosis complex under age 4, and 20 age-matched controls, using a familiar-unfamiliar faces paradigm. Of the children, 6 with tuberous sclerosis complex (32%) had autism. Children with tuberous sclerosis complex showed a longer N290 latency than controls (276 ms vs 259 ms, P = .05) and also failed to show the expected hemispheric differences in face processing. The longest N290 latency was seen in (1) children with autism and tuberous sclerosis complex and (2) children with temporal lobe tubers. This study is the first to quantify atypical face processing in children with tuberous sclerosis complex. This functional impairment may provide insight into a mechanism underlying a pathway to autism in tuberous sclerosis complex.

Enhanced visual functioning in autism: An ALE meta‐analysis

Autistics often exhibit enhanced perceptual abilities when engaged in visual search, visual discrimination, and embedded figure detection. In similar fashion, while performing a range of perceptual or cognitive tasks, autistics display stronger physiological engagement of the visual system than do non-autistics. To account for these findings, the Enhanced Perceptual Functioning Model proposes that enhanced autistic performance in basic perceptual tasks results from stronger engagement of sensory processing mechanisms, a situation that may facilitate an atypically prominent role for perceptual mechanisms in supporting cognition. Using quantitative meta-analysis of published functional imaging studies from which Activation Likelihood Estimation maps were computed, we asked whether autism is associated with enhanced task-related activity for a broad range of visual tasks. To determine whether atypical engagement of visual processing is a general or domain-specific phenomenon, we examined three different visual processing domains: faces, objects, and words. Overall, we observed more activity in autistics compared to non-autistics in temporal, occipital, and parietal regions. In contrast, autistics exhibited less activity in frontal cortex. The spatial distribution of the observed differential between-group patterns varied across processing domains. Autism may be characterized by enhanced functional resource allocation in regions associated with visual processing and expertise. Atypical adult organizational patterns may reflect underlying differences in developmental neural plasticity that can result in aspects of the autistic phenotype, including enhanced visual skills, atypical face processing, and hyperlexia.

Atypical face processing and resistance to change in children with autism and their evolution throughout therapy

Event Abstract Back to Event Atypical face processing and resistance to change in children with autism and their evolution throughout therapy Emilie Meaux1*, Pascale Dansard2, Romuald Blanc2, Joëlle Malvy2, Catherine Barthélémy2, Frédérique Bonnet-Brilhault2, Marie Gomot2 and Magali Batty2 1 INSERM U930, Team 1, France 2 UMRS « Imagerie et cerveau », INSERM U930 Team 1, CNRS ERL 3106, Université François Rabelais de Tours, CHRU de Tours, France Difficulties in social interaction (e.g. face processing) and resistance to change are main features of autism (ASDs) and the brain processes underlying these aspects of the disorder are reported to be abnormal. Based on the neurodevelopemental theory of autism, the exchange and development therapy (EDT) consists in the early re-education of the basic neurophysiologic functions. Previous studies have confirmed the efficiency of the EDT in ASDs, showing a decrease of the inappropriate behaviours and an increase in cognitive and social abilities. However, the cerebral correlates that underlie these improvements have never been studied. The first aim of this study was to investigate neural basis of face processing and auditory change-detection in children with ASDs through electrophysiological indices (N170, MMN). The Second purpose was to investigate the evolution of those indices before and after the EDT and to test whether these are related to clinical improvements using SCEB (socio-emotional skills) and BSE-R scale (change detection abilities). ASDs displayed abnormal visual ERPs in response to face (P1, N170) and atypical MMN compared to controls confirming that these two processes, involved in social adaptation, are affected in autism. Moreover one year after the beginning of the therapy, all the clinical, behavioural and electrophysiological indices appear to be affected by the EDT. These preliminary findings are very encouraging and suggest an effect of therapy on brain development in agreement with the principles of the EDT. Keywords: autism, Neuropsychiatry Conference: XI International Conference on Cognitive Neuroscience (ICON XI), Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011. Presentation Type: Poster Presentation Topic: Poster Sessions: Neuropsychiatric Applications Citation: Meaux E, Dansard P, Blanc R, Malvy J, Barthélémy C, Bonnet-Brilhault F, Gomot M and Batty M (2011). Atypical face processing and resistance to change in children with autism and their evolution throughout therapy. Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI). doi: 10.3389/conf.fnhum.2011.207.00234 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 21 Nov 2011; Published Online: 28 Nov 2011. * Correspondence: Dr. Emilie Meaux, INSERM U930, Team 1, Tours, France, e.meaux@chu-tours.fr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Emilie Meaux Pascale Dansard Romuald Blanc Joëlle Malvy Catherine Barthélémy Frédérique Bonnet-Brilhault Marie Gomot Magali Batty Google Emilie Meaux Pascale Dansard Romuald Blanc Joëlle Malvy Catherine Barthélémy Frédérique Bonnet-Brilhault Marie Gomot Magali Batty Google Scholar Emilie Meaux Pascale Dansard Romuald Blanc Joëlle Malvy Catherine Barthélémy Frédérique Bonnet-Brilhault Marie Gomot Magali Batty PubMed Emilie Meaux Pascale Dansard Romuald Blanc Joëlle Malvy Catherine Barthélémy Frédérique Bonnet-Brilhault Marie Gomot Magali Batty Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Atypical Face Versus Object Processing and Hemispheric Asymmetries in 10-Month-Old Infants at Risk for Autism

Previous studies have documented atypicalities in face/object processing in children and adults with autism spectrum disorders (ASDs). To investigate whether such atypicalities may reflect a genetically mediated risk factor present early in development, we measured face/object processing in 10-month-old high-risk infants who carry some of the genes associated with ASD because they have an older sibling diagnosed with the disorder. We employed event-related potentials (ERPs) to measure cortical responses to pictures of faces and objects, the objects being toys. Latencies and amplitudes of four ERP components (P100, N290, P400, and Nc) were compared between 20 high-risk infants and 20 low-risk control subjects (infants with no family history of ASD). Responses to faces versus objects differed between high- and low-risk infants for the latencies of the N290 and P400. Differences were driven by faster responses to faces than objects in low-risk, but not high-risk, infants (P400) and, conversely, faster responses to objects than faces in high-risk, but not low-risk, infants (N290). Object responses were also faster in high-risk than low-risk infants (both N290 and P400). Left versus right hemisphere responses also differed between high- and low-risk infants for the amplitudes of the P100, N290, and P400; collapsed across faces/objects, low-risk, but not high-risk, infants exhibited hemisphere asymmetries. Genetic risk for ASD is associated with atypical face versus object processing and an atypical lack of hemispheric asymmetry early in life. These atypicalities might contribute to development of the disorder.

Response to Smith’s Letter to the Editor ‘Emotional Empathy in Autism Spectrum Conditions: Weak, Intact, or Heightened?’

Dear Editor, We read with interest the Letter by Smith (2009) suggesting that individuals with Autism Spectrum Conditions (ASC) have heightened emotional empathy (EE). We are pleased to be invited to contribute to the discussion. We do this by commenting on both the evidence cited by Smith, and also the evidence he does not cite. We conceptually reframe the question being posed and argue that, in the light of a broader review of the evidence, empathic responses in people with ASC are in general reduced. However, a basic type of empathic response that would fall into Smith’s definition of EE may indeed be heightened (a self-oriented personal distress response to others’ distress). We end by suggesting additional avenues to be explored. Empathy is a process where another person’s mental state (which include intentions, desires, emotions and proprioceptive states) automatically activates in the observer a representation of the observed state. These representations, unless inhibited, prime associated autonomic and somatic responses in the observer, thus generating a state in the observer that is more appropriate to the state of the person being observed (Baron-Cohen and Wheelwright 2004). The empathic process can therefore be considered as a superordinate category that includes many phenomena sharing this same underlying mechanism (Preston and de Waal 2002). Minio-Paluello et al. (2009) addressed the embodied side of empathy in people with ASC by investigating the response to others’ pain using a paradigm that involved watching a hand being penetrated by a needle. Facial or vocal representations of pain were not shown, to avoid any confound due to emotion recognition difficulties (Humphreys et al. 2007; Ashwin et al. 2006; Kuusikko et al. 2009) or atypical face processing (Spezio et al. 2007; Behrmann et al. 2006) in ASC. This study found that when observing another person’s physical pain, unlike controls, participants with ASC did not show a neurophysiological response as if they were experiencing pain themselves, and nor did their neurophysiological response correlate with the imagined pain sensory qualities. Instead, participants with ASC represented others’ pain in relation to the level of self-oriented arousal experienced while watching pain affecting another person. Further, participants with high empathy and a low number of autistic traits showed a stronger embodied empathy response. Thus, embodiment of another person’s state is one possible mechanism underlying the empathic process (Niedenthal 2007; Gallese 2007) and one that seems reduced in ASC (Minio-Paluello et al. 2009; Williams 2008). Reduced embodiment in people with ASC does not directly relate to their level of EE, defined by Smith (2009) as ‘an emotional response in an individual that stems from and parallels the emotional state of another individual’ (italics added). In the study by Minio-Paluello et al. (2009), for example, neither participants with ASC nor controls reported vicariously experiencing any pain while watching the model’s hand being penetrated by the needle. I. Minio-Paluello (&) Dipartimento di Psicologia La Sapienza, Universita’ di Roma, Via dei Marsi 78, 00185 Rome, Italy e-mail: ilaria.miniopaluello@uniroma1.it

The eyes or the mouth? Feature salience and unfamiliar face processing in Williams syndrome and autism

Using traditional face perception paradigms the current study explores unfamiliar face processing in two neurodevelopmental disorders. Previous research indicates that autism and Williams syndrome (WS) are both associated with atypical face processing strategies. The current research involves these groups in an exploration of feature salience for processing the eye and mouth regions of unfamiliar faces. The tasks specifically probe unfamiliar face matching by using (a) upper or lower face features, (b) the Thatcher illusion, and (c) featural and configural face modifications to the eye and mouth regions. Across tasks, individuals with WS mirror the typical pattern of performance, with greater accuracy for matching faces using the upper than using the lower features, susceptibility to the Thatcher illusion, and greater detection of eye than mouth modifications. Participants with autism show a generalized performance decrement alongside atypicalities, deficits for utilizing the eye region, and configural face cues to match unfamiliar faces. The results are discussed in terms of feature salience, structural encoding, and the phenotypes typically associated with these neurodevelopmental disorders.

Typical Emotion Processing for Cartoon but not for Real Faces in Children with Autistic Spectrum Disorders

This study evaluated whether atypical face processing in autism extends from human to cartoon faces for which they show a greater interest. Twenty children with autistic spectrum disorders (ASD) were compared to two groups of typically developing children, matched on chronological and mental age. They processed the emotional expressions of real faces, human cartoon and nonhuman cartoon faces. Children with ASD were as capable as controls in processing emotional expressions, but strategies differed according to the type of face. Controls relied on a configural strategy with all faces. By contrast, ASD children exploited this typical configural strategy with cartoons but used a local strategy with real faces. This atypical visual processing style is discussed in the context of face expertise.