This study investigated smallholder farmers’ perceived motivations for the adoption and implementation of climate information services (CIS) in the Atwima Nwabiagya District, Ghana. Specifically, the study answered the following research questions. (i) What is the perception of smallholder farmers on climate change and variability in the Atwima Nwabiagya District?; (ii) What are the CIS accessed and used by the smallholder farmers for farm management decisions?; (iii) What are the perceived motivations for the adoption and implementation of CIS by smallholder farmers?; and; (iv) What are the barriers confronting smallholder farmers in adopting and implementing CIS? Primary data was collected through questionnaire surveys with 200 farming households and four key informant interviews in four selected communities (Kobeng, Seidi, Wioso, and Nkawie Panin) in the study district. Results showed that smallholder farmers perceived climate change and variability through increased windstorms and thunderstorms, variable rainfall, and increased temperature patterns. The surveyed farmers also perceived that the climatic changes affect their agricultural activities adversely. However, the smallholder farmers accessed and used CIS including weather warnings (86%), daily weather forecasts (70%), and seasonal forecasts (60%) to manage climatic risks on the farm. Results also showed that the smallholder farmers were motivated by critical factors including improvement in the acquisition of proactive measures (92%), increased knowledge of climatic patterns that affect food stock (91%), and a reduction in loss of stock produced (88%) to access and use CIS. Despite this, the smallholder farmers were confronted with key barriers in their uptake and utilization of CIS. These were the timeliness of CIS (73%), a lack of weather symbols in the forecasts (65%), and inadequate information on seasonal forecasts for long-term planning (61%). The study concluded that the motivations for smallholder farmers using CIS in the study district may vary depending on their context, goals, and challenges. However, the general motivation is to enhance smallholder farmers’ farm planning and risk management by using weather and climate forecasts to make better decisions on crop selection, planting dates, input use, pest and disease control, irrigation, harvesting, and marketing.