Asymptomatic Bacteriuria In Pregnancy Research Articles

Asymptomatic bacteriuria in pregnancy and its outcome

Asymptomatic bacteriuria in pregnancy and its outcome

Prevalence and Its Antibacterial Susceptibility Pattern of Asymptomatic Bacteriuria in Pregnancy of a Teaching Hospital

Prevalence and Its Antibacterial Susceptibility Pattern of Asymptomatic Bacteriuria in Pregnancy of a Teaching Hospital

Asymptomatic Bacteriuria in Pregnancy Causes and Incidence

OBJECTIVES This study aims to provide an understanding of asymptomatic bacteriuria in pregnancy by examining its frequency, causative agent, and potential strategies for detection and management. METHODOLOGY A cross-sectional study was conducted in the Department of Obstetrics and Gynecology, PGMI Hayatabad Medical Complex, Peshawar, from July to December 2022. The study included 117 antenatal patients with varying gestational periods attending the OPD. Patients with a history of antibiotic therapy, urinary frequency and dysuria, vaginal discharge, renal tract anomalies, and medical disorders were excluded. Demographic details were recorded, and urine samples were collected and cultured. Data was analyzed using SPSS version 22. RESULTSThe incidence of asymptomatic bacteriuria was 25.5%, among 117 women, with E. coli (53.3%) the most common pathogen responsible for the infection, followed by Klebsiella (36.7%) and staphylococcus (10%).CONCLUSIONBacteriuria without causing any symptoms is quite common in pregnancy. Simple measures like screening early in pregnancy can timely detect positive cases and with targeted treatment, both maternal and neonatal morbidity can be curtailed.

Bacterial abundance and antimicrobial resistance patterns of uropathogens among pregnant women with asymptomatic bacteriuria: Association with glycemic status

ObjectivesAntimicrobial resistance (AMR), a growing global menace, poses a significant threat to maternal and fetal health. Gestational diabetes mellitus (GDM) causes double trouble in pregnancy, increasing the risk of a variety of infectious morbidities while also raising the possible association with AMR. Asymptomatic bacteriuria (ASB) is a common problem in pregnancy, but little research has been done to date explicitly examining the relationship between GDM and ASB and yielded conflicting results. Even fewer studies have specifically examined the relationship between GDM and AMR in women with ASB. Retrieving the most recent information on the disease burden, the range of causative pathogens, their patterns of AMR, and associated risk factors in pregnant women is crucial to stop the exponential rise in AMR in pregnancy and improve maternal and neonatal outcomes of infectious morbidities. Hence, this study was planned to investigate the association between glycemic status and the contemporary bacterial profile, antimicrobial resistance(AMR), and associated variables among pregnant women with ASB Study designThis prospective, hospital-based, cross-sectional study was conducted among 320 pregnant women; divided into two groups, GDM and non-GDM. Data regarding sociodemographic and clinical characteristics were collected using a structured questionnaire. Clean-catch midstream urine samples were investigated for the presence of significant bacterial uropathogens and their AMR pattern was determined using recommended culture methods. ResultsWe found ASB in 46.25% of study participants with significantly higher occurrence in the GDM group. Dominant isolates were Escherichia coli followed by Klebsiella pneumoniae. AMR was noted in 51.35% and multidrug resistance(MDR) in 23.65% of isolates. Overall AMR, MDR and higher degrees of AMR were higher among uropathogens isolated from the GDM group as compared to the non GDM group, although the difference was not statistically significant. ConclusionThe high occurrence of ASB in pregnancy along with substantially high AMR in this study suggests the need for effective infection control and stewardship programmes. By defining the association of ASB and AMR with hyperglycemia, our study calls for the exploitation of this potential association in halting the pandemic of AMR and in improving the management of infectious morbidities, thus in-turn alleviating their undesired maternal and infant outcomes.

Clinico-microbiological Profile and Outcomes of Asymptomatic Bacteriuria in Pregnancy.

Asymptomatic bacteriuria (ASB) during pregnancy can lead to symptomatic urinary tract infection (UTI), with increased fetal and maternal morbidity and mortality. We evaluated the incidence, clinical and microbiological profile, and outcome of ASB in pregnant women attending our antenatal clinic. This prospective study was conducted on 3769 pregnant women in a routine antenatal clinic at a tertiary care center. Participants were divided into two groups, ASB and non-bacteriuria. Data were collected in a standard proforma and analyzed using the software Statistical Package for the Social Sciences (SPSS) v. 20. The incidence of ASB was 3.29% (124/3769). Majority of the women were in the age group of 21-30 years (78.76%, n = 89). Escherichia coli (61.06%) was the most common organism isolated. Maternal anemia (30.08% and 2.93% in the ASB and non-bacteriuria groups, respectively), low birth weight (LBW; 42.5% and 27.98% in the ASB and non-bacteriuria groups, respectively), intrauterine death (4.4% and 1.4% in the ASB and non-bacteriuria groups, respectively), and preterm delivery (37.2% and 22.31% in the ASB and non-bacteriuria groups, respectively) were were associated with ASB (P = 0.001). ASB was associated with maternal anemia, preterm delivery, intrauterine death, and LBW. Early detection and treatment of ASB may result in favorable maternal outcome.

To screen or not to screen for asymptomatic bacteriuria in pregnancy: A comparative three-year retrospective review between two maternity centres

BackgroundCurrent national guidance in Ireland states that asymptomatic bacteriuria (AB) should be screened for at 12–16 weeks’ gestation and treated with a seven-day course of antimicrobials, due to the potential risk of preterm birth and low birth weight infants (LBWI), however, this is based on low quality evidence. MethodsOver a three-year period (2018–2020), a retrospective review was undertaken in two neighbouring maternity hospitals; one of which screens for AB (Rotunda hospital (RH)) and one which does not (National Maternity Hospital (NMH)). Patients were included on the basis of fulfilling the IDSA definition for pyelonephritis and requiring admission for intravenous antibiotics. Rates of antenatal pyelonephritis were compared between hospitals, and between screened and unscreened populations. Secondary outcomes including rates of preterm births and LBWI were compared across sites. ResultsA total of 47,676 deliveries between the two centres (24,768 RH; 22,908 NMH) were assessed, of which 158 patients met inclusion criteria for antenatal pyelonephritis (n = 88 RH, n = 70 NMH). There was no statistically significant difference in the rate of antenatal pyelonephritis (p = 0.34) or preterm births (p = 0.21) across sites. RH had a significantly higher rate of LBWI at 6.45% versus 5.68% of all births in NMH (p=<0.004). Given the screening rate in RH was below 100%, this cohort was further subdivided into ‘RH screened’ and ‘RH unscreened’. There was no statistically significant difference in the rate of antenatal pyelonephritis both between the ‘NMH unscreened’ group (n = 70) versus the ‘RH screened’ group (n = 62) (p = 0.53), or in the ‘RH screened’ group (n = 62) versus the ‘RH unscreened’ group (n = 26) (p = 0.53). ConclusionOmission of a screening programme for AB in NMH did not result in higher rates of antenatal pyelonephritis, preterm birth or LBWI. Our findings may inform decision-making on screening protocols and whether selective screening (i.e. screening in high-risk patients only) could be more cost-effective without compromising best quality of care.

Prevalence of asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women

Background and Aim: The condition of asymptomatic bacteriuria in pregnancy is common, and up to 40% of women developing pyelonephritis in pregnancy may suffer low birth weight and membrane’s premature rupture. The present study intended to investigate the incidence of asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women. Patients and Methods: This cross-sectional study was carried out on 183 pregnant women attending Obstetrics and Gynecology Department of Ayub Teaching Hospital, Abbottabad from December 2021 to May 2022. Pregnant women with asymptomatic bacteriuria attended the ANC services and willing to provide written consent were enrolled. Standard bacteriological procedures were followed for bacterial isolates identification using biochemical tests, colony characteristics, and Gram-staining. Kirby- Bauer disk diffusion technique was used for Antimicrobial susceptibility test on Muller-Hinton agar medium and Clinical Laboratory Standard Institute guidelines was used for interpretation of zone of inhibition diameter. Midstream urine samples were collected from each study participant and standard microbiological methods to culture urine, identify the pathogen, and conduct sensitivity tests. Data analysis was done in SPSS version 27. Results: The prevalence of asymptomatic bacteriuria was 14.2% (n=26) among pregnant women.

Asymptomatic bacteriuria in pregnancy

Asymptomatic bacteriuria (ASB) is diagnosed by the presence of a 10*5 colony-forming units (CFU) in the urine without any urinary symptoms. It commonly occurs in pregnancy with the incidence ranging from 2-10%. It poses a risk of progressing into pyelonephritis in pregnancy. Adverse fetal outcomes include preterm labor, neonatal sepsis, intrauterine growth restriction (IUGR) and neonatal death. Anatomical and physiological changes during pregnancy make pregnant women more vulnerable to ASB and subsequently symptomatic UTI. E coli is the commonest organism involved in ASB, followed by Klebsilla and Enterobactericiae. Evidence suggests that importance of routine screening for ASB in early pregnancy to avoid adverse fetomaternal outcomes. Reduced adverse outcomes were noted with prompt antibiotic treatment for ASB compared to untreated pregnant women with ASB. Urine culture remains as the gold standard method to diagnose ASB in pregnancy. Using urine culture as a routine screening method in Sri Lanka is limited due to financial restrictions.

Asymptomatic bacteriuria in pregnancy.

Asymptomatic bacteriuria (ASB) is associated with adverse maternal and neonatal outcomes and is routinely screened for and treated in the first trimester. Prevalence of ASB in the second and third trimesters of pregnancy is unknown. The aim is to determine the prevalence of ASB in the second and third trimesters of pregnancy. Prospective cohort study of 150 pregnant women. Mid-stream urine samples were tested for ASB in the second (24-28+6 ) and third (32-36+6 ) trimesters. Women were assigned to one of two groups: (i) ASB in any trimester of pregnancy and (ii) no evidence of ASB in pregnancy. Maternal and neonatal outcomes were compared between groups. Among 143 women included in the study, the rate of ASB was 4.9% (2.1, 2.1 and 3.2% in the first, second and third trimesters, respectively). Of those with ASB, 14% had it in every trimester, whereas 43% had it on two or more samples. Of those with ASB in pregnancy, 43% were detected for the first time in the third trimester. Rates of maternal and neonatal outcomes were not statistically significantly different between the two groups. No women with ASB were induced for chorioamnionitis or growth restriction. The rate of ASB was highest in the third trimester of pregnancy, with rates of 2.1, 2.1 and 3.2% in the first, second and third trimesters, respectively. This study was underpowered to assess maternal and fetal outcomes. Although numbers were small, the absence of ASB in the first trimester was a poor predictor of ASB in the third trimester.

Asymptomatic bacteriuria in pregnant Nigerian women at the Lagos University Teaching Hospital, south west Nigeria

Background: Dipstick urinalysis is a handy and cost effective method for the early detection of asymptomatic bacteriuria. Asymptomatic bacteriuria occurs in 2-10% of pregnancies and has been associated with low birth weight and preterm delivery in pregnant women if untreated. Objective: To determine the incidence of asymptomatic bacteriuria in pregnancy, the distribution of infecting organisms and the antibiotic sensitivity pattern in pregnant Nigerian women attending the antenatal clinic of the Lagos University Teaching Hospital, Idi- Araba, Lagos. Methodology: This was a prospective study. The study population were 201 consecutive asymptomatic pregnant women, who attended the antenatal clinic of LUTH for booking between 1st July and 31st December, 2021. Two consecutive urine samples were collected and analysed for microscopy, culture and sensitivity and urinalysis. The outcomes of interest were prevalence of asymptomatic bacteriuria at LUTH, bacterial isolates, and their antibiotic sensitivity pattern. Results: The mean age of the population studied was 31years ± 4.56SD. The mean gestational age was 23.8 ± 5.39 SD with a range of 11-34 weeks; and majority of the participants (65.7%) were recruited at gestational ages between 14 and 26 weeks. The prevalence of asymptomatic bacteriuria in this study was 13.9%. The commonest isolated organism was klebsiella (46.4%) followed by Escherichia coli (21.4%). Ceftazidime, ofloxacin, and gentamycin showed good overall sensitivity with 92.9%, 89.3%, and 67.9%% respectively. From the results of urinalysis, nitrites showed a sensitivity of 48.3% and specificity of 98.2% with a positive predictive value of 83.3% while presence of bacterial cells on urine microscopy showed sensitivity of 31.2%, specificity of 85% and a positive predictive value of 27%. Conclusion: The incidence of asymptomatic bacteriuria in this study was considerably high and therefore, there may be need to consider introduction of routine urine culture at booking or in the second trimester.

Prevalence and its antibacterial susceptibility pattern of asymptomatic bacteriuria in pregnancy of a teaching hospital

Prevalence and its antibacterial susceptibility pattern of asymptomatic bacteriuria in pregnancy of a teaching hospital

Profile of uropathogens in pregnancy over 5 years from a large tertiary center in South India

Objectives: Urinary tract infections (UTIs) are a common medical problem in both antenatal and postnatal women. Data from India on the demography of these women, microbiology and antimicrobial susceptibility of the causative bacteria, need elucidation. Material and Methods: We performed an observation study that collected data on UTI in antenatal and postnatal women between 2013 and 2017 at our tertiary care center in South India. Antenatally, urine dipstick-positive patients, high-risk, and symptomatic patients submitted urine cultures. Postnatally, all symptomatic patients had urine cultures. This was 20% of all antenatal and postnatal women resulting in 20,203 cultures. Results: Of 20,203 cultures, significant bacteriuria was seen in 9.48% of antenatal and 13.28% of postnatal women. A higher mean age was seen among those with UTI, antenatal 27 (SD 3.5) and postnatal 26.4 (SD 4.7) years versus 23.9 (SD 3.6) with no growth in culture. The mean BMI among antenatal was 28.2 (SD 3.5) and postnatal was 28 (SD 7.4). Most (60%) were primigravida. At delivery, 37% required cesarean sections while 21.2% required instrumental delivery. Recurrent UTI was seen in 25% antenatally and 10% in the postnatal period. Escherichia coli accounted for 66 and 60% of infections among antenatal and postnatal women, respectively. Enterococcus species accounted for 13% in both while Klebsiella species was 4.9 and 7.3%, respectively. Among E. coli, 68.3 and 59.2% of isolates in antenatal and postnatal period were cefpodoxime susceptible. Nearly 75% of ante- and postnatal isolates were susceptible to amoxicillin-clavulanate while 90.2% and 92.5% were susceptible to nitrofurantoin. Enterococci spp. up to 84.4 and 97.1% in ante- and postnatal isolates were susceptible to ampicillin, 64.4 and 77.4% susceptible to high-level gentamicin, and 84 and 95.5% susceptible to nitrofurantoin. Asymptomatic bacteriuria in pregnancy was documented in 2.1% of antenatal outpatients and E. coli was isolated in 74% of these cultures. Conclusion: Importance of microbiological evidence prior to administration of antimicrobials is evidenced by 79% negative cultures in this 5-year cohort. Escherichia coli accounted for 60-66% of significant bacteriuria followed by Enterococcus and Klebsiella species with 30-40% E.coli probable ESBL producers. Nitrofurantoin followed by amoxicillin-clavulanate were found to be the best oral antimicrobial options.

The Accuracy of Rapid Urine Tests in Detecting Asymptomatic Bacteriuria in Pregnancy at University of Maiduguri Teaching Hospital, Maiduguri, Nigeria

Background: Asymptomatic bacteriuria (ASB) is the most prevalent Urinary tract infection (UTI). The gold standard for detecting ASB is urine culture, which requires trained personnel who are not always readily available in some parts of the world. Quick office-based tests such as urine microscopy and reagent strip testing are also used as screening tests at points of care, reserving culture for positive and symptomatic cases. Objectives: This study determined the risk factors for ASB and the accuracy of reagent strip testing and microscopy in detecting ASB among pregnant women. Methods: A cross-sectional study of 150 women attending the antenatal clinic of the University of Maiduguri Teaching Hospital (UMTH) in Maiduguri, Nigeria, was conducted from 3rd October to 13th December 2010. Demographic and clinical variables were obtained. Midstream urine specimens were collected from each patient and used for reagent strip testing, microscopy, culture and antibiotic susceptibility testing. The performance of the various tests alone and in combination was evaluated using urine culture as the standard. Results: Sickle cell trait, history of UTI before index pregnancy and anaemia at booking were significant risk factors for the development of ASB. A combination of positive leucocyte esterase and nitrite tests had specificity and a positive predictive value of 100% each. Similarly, the combination of pus cell count and gram stain, termed enhanced urinalysis had specificity and positive predictive values of 99.1% and 95.0%, respectively. Conclusion: Sickle cell trait, UTI before index pregnancy and anaemia at booking are significant risk factors for ASB. A combination of negative dipstick leucocyte esterase, nitrite, and negative enhanced urinalysis effectively rules out ASB. Urine culture can be restricted to positive and symptomatic patients.

Prevalence of asymptomatic Bacteriuria among Pregnant Women in Sirte City (Libya).

Asymptomatic bacteriuria (ASB) is known as significant presence of pathogenic bacteria more as 105 CFU/ml in urine culture of pregnant women without any symptoms indicate of urinary tract infections. Which is may lead to serious complications on health of a pregnant woman, and the fetus if left untreated. The purpose of this study was designed to find the prevalence of asymptomatic urinary tract infection (AUTI) among pregnant women, and also to determine the antibacterial susceptibility of the isolates to various antibiotics to reduce risk factors in pregnancy. However, little is known about asymptomatic bacteriuria in pregnancy in Libya, namely in Sirte city. A total of 265 samples were collected in 7 months study involving women attending antenatal clinics in Sirte City-Libya, mid-stream urine samples were collected for microscopically examination. A colony culture growth were identified by biochemical tests and conventional antibiotic susceptibility tested in microbiology laboratory. Isolates were identified and tested against commonly used antimicrobial drugs using Kirby Bauer disc diffusion method. The prevalence of 265 pregnant women in different age groups were enrolled in this study, only 76 (28.7%) pregnant women had bacteriuria. The organism isolated from the urine sample according to the frequency of occurrence was Escherichia coli 32(42.1%), Coagulase negative Staphylococcus 11 (14.4%), Staphylococcus aureus 9(11.8%), Klebsiella Pneumoniae 9(11.8%), Streptococcus agalactiae 8 (10.5%), Enterococcus spp 5(6.6%), Proteus mirabilis 2(2.6%), respectively. The overall prevalence of asymptomatic bacteriuria among pregnant women in the study area was not high, but need to be taken on consider reducing risk of infections. The presence of asymptomatic bacteriuria and their antibiotic susceptibility test results should be taken into consideration during the management of pregnant women who are visiting antenatal care clinic; because there was high resistance to the most commonly used antibiotics. Routine urine culture and antimicrobial sensitivity for antenatal women should be carried out to detect asymptomatic bacteriuria to treat early infections, to prevent any serious complication associated with pregnancy.

Evaluation of socio- demographic risk factors for asymptomatic bacteriuria in pregnancy

Background: Asymptomatic Bacteriuria in pregnancy though common often goes undiagnosed till overt U.T.I. occurs. It leads to various maternal and fetal complications. Many factors influence its occurrence. The aim of the study was to evaluate socio-demographic risk factors of asymptomatic bacteriuria. Methods: A hospital based observational study done over one year in the antenatal clinic of a tertiary care hospital. Urine of all the pregnant women was sent for complete microscopy and culture &amp; sensitivity. Socio-demographic profile of all women was noted and data analysed. Results: Of the 450 women included in study, 8.22% had asymptomatic bacteriuria. It was significantly more in the less educated, in those residing in rural and semi-urban areas or belonging to socioeconomic group IV. Conclusion: All pregnant women must be universally screened for asymptomatic bacteriuria. In case it is not feasible, women with high risk factors should be identified and selectively screened.

Role of routine urine culture in predicting asymptomatic bacteriuria in pregnancy and the prevalence of asymptomatic bacteriuria in pregnant women - Our experience

Asymptomatic bacteriuria (ASB) in pregnancy can flare into frank pyelonephritis and sepsis if untreated due to the low immunity. Apart from causing morbidity in mothers it affects the foetus by increasing the incidence of prematurity and IUGR. The present study was undertaken to determine the prevalence of ASB in the pregnant women attending Ante natal clinic and the significance of routine urine culture. : Total 310 pregnant women attending the antenatal OPD were enrolled in the study over a period of 10 months. Inclusion criteria included all pregnant women attending antenatal OPD without any urinary symptoms or history of fever. Exclusion criteria included frank UTI symptoms like fever, dysuria, increased frequency of urine, any history of intake of antibiotics, any urinary tract anomaly or renal calculi. Their midstream urine sampling was collected and subjected to both microscopy and culture sensitivity; standard microbiological method was used. The prevalence of ASB was found to be 11.29% and was maximum in second trimester (54.2%). The study revealed routine urine culture is a sensitive test to diagnose ASB. The commonest bacterium isolated was Escherichia coli (51.4% cases) and the most effective antibiotic was Nitrofurantoin. The neonatal outcomes are discussed in the text while no perinatal deaths were recorded during the period of study. No direct association of asymptomatic bacteriuria with anaemia and preeclampsia was found, but odds ratio was more than one. The study highlights that asymptomatic bacteriuria is a common occurrence in pregnant women, including urine culture as a part of routine investigation in antenatal patients can help diagnose this condition. Prompt treatment of ASB can prevent any obstetric complication arising from the flareup of asymptomatic bacteriuria in pregnancy and thus reduce maternal and foetal morbidity.

Prevalence of Asymptomatic Bacteriuria in Pregnancy and Urinary Tract Infection in Non-pregnant Symptomatic Womem

Prevalence of Asymptomatic Bacteriuria in Pregnancy and Urinary Tract Infection in Non-pregnant Symptomatic Womem

English

Asymptomatic bacteriuria can lead to urinary tract infections in as many as 20% of pregnant women. Asymptomatic bacteriuria in pregnancy can also lead to preterm births and low birth weights. The objective of this study was to profile uro-pathogens and describe the population-based prevalence, the antimicrobial sensitivity pattern, and ascertain the risk factors for asymptomatic bacteriuria among pregnant women attending the antenatal clinic of Ho Teaching Hospital, in Ghana. Urine samples were cultured, isolates identified and antibiotic sensitivity testing was done using the Clinical and Laboratory Standard Institute (CLSI) guidelines. 46 (13.7%) out of 335 pregnant women had asymptomatic bacteriuria. The most frequently isolated bacteria were Pseudomonas species (26.1%) followed by Escherichia coli (21.7%). All isolates (n=46; 100%) were resistant to Augmentin whereas 87% of the isolates (n=40) were susceptible to Gentamicin. However, most of the isolates were multi-resistant to antibiotic drugs. No education (p=0.019) and first trimester (p=0.046) of pregnancy were risk factors for asymptomatic bacteriuria. Pseudomonas aeruginosa was the most frequent organism isolated. All the uro-pathogens were resistant to Augmentin, while high rates of resistance to Tetracycline, Amikacin, Norfloxacin, and Levofloxacin were observed. The study reveals that asymptomatic bacteriuria was significantly associated with the first trimester of pregnancy and having no education. &nbsp; Key words: Bacteriuria, urinary tract infections, prevalence, Ghana, Ho Teaching Hospital, antimicrobial resistance.

Prevalence of Asymptomatic Bacteriuria among Pregnant Women At Damietta Governorate, Egypt

Background:Asymptomatic bacteriuria during pregnancy is a main health problem, which is related to an increased risk of maternal and fetal morbidity. Aim of the Work:To estimate incidence of asymptomatic bacteriuria among pregnant females at Damietta Governorate, Egypt. Patients and Methods:Five hundred randomly selected pregnant females attending antenatal care units at Damietta Governorate during the period July, first, 2019 – January 31st, 2021. All participants were subjected to full history taking, complete blood count as well as urine culture and bacterial count. Result:A relatively high incidence of asymptomatic bacteriuria [13.8%] was revealed among participants in whom the most causative organism was Escherichia coli. The rate was lower among pregnant women with a high social standard and during the first trimester. Maternal age, parity, education level, or hemoglobin level, on the other hand, had no significant relationship . Conclusion: Screening of asymptomatic bacteriuria in pregnancy must be added to routinely antenatal care investigations and doing another studies on a wider scope are recommended.

Risk Factors during Pregnancy for Asymptomatic Bacteriuria

Introduction: Asymptomatic bacteriuria in pregnancy (ABU) is poorly understood and neglected in developing countries. It causes certain lethal maternal and fetal consequences if left untreated including low weighted births, premature delivery, full-blown urinary tract infection and pyelonephritis.&#x0D; Objective: Our aim was to explore such factors having bad impact on pregnancy associated with asymptomatic bacteriuria and aware our community about these unspoken perils so that ABU likelihood may be reduced. Prevalence varies country to country. Developing and low economic countries are suffered more than developed so thereby upgrading and providing basic amenities of life the risk factors may be reduced.&#x0D; Materials and Methods: This was a cross sectional study carried out in department of pathology PUMHSW. Sample size was 377, all selected were 18 years and above. All urinary samples were collected in sterile container and labeled and immediately transported to microbiology laboratory. Dipstick test, wet mount microscopy and Gram's staining were done. Blood, MacConkey's agar was inoculated and streaked with inoculi. Data were analyzed using SPSS version 23.&#x0D; Results: Samples found unlabeled (02) and contaminated (03) were dropped from study. A total of 372 were study samples. The most of patients were Gram negative 65(90.20%) predominantly Enterobacteriocae. When cultured, 72 were found growth positive (mixed plus pure) while 300 were negative. Risk factors were assayed in culture positive patients (ABU). A large number of patients (74%) belonged to lower economic class. Most common age group varied from 26-30 years (43%). Third trimester was the most common found in 37 patients ((49.3%). Gravid (G3 or more) were strong risk factors and were 55(73.3%). Most of patients were illiterate 65 (90.27%). The past history of UTI was a significant risk 46(63.88%) while anemia was found statistically insignificant 17(23.61).&#x0D; Conclusion: Asymptomatic bacteriuria is frequent in pregnant females and significantly increased when compounded by past history of UTI and low socioeconomic status. Therefore, it is necessary for mothers to be screened for ABU. There is a need of rapid and reliable screening methods so that upcoming disease burden can be reduced.