Facial Asymmetry Research Articles

Artificial Intelligence-based Assessment of Facial Symmetry Aesthetics of Saudi Arabian Population.

The purpose of this study is to investigate facial symmetry aesthetics (FSA) in the Saudi Arabian population using artificial intelligence (AI).Two hundred and ten people from a range of demographic backgrounds participated in an observational cross-sectional study that was done at a hospital. Standardized posed photos of the face and smile were taken using a Canon camera utilizing a stratified random sample approach. Webceph software (Korea) with AI was used to evaluate macro, micro, and tiny aesthetic factors. The data were analyzed using paired t-tests, post hoc Bonferroni testing, analysis of variance (ANOVA), and descriptive statistics. The computation of intraclass correlation coefficients (ICCs) was utilized to assess the dependability of AI evaluations.All variables had ICCs of more than 0.97, indicating exceptional dependability for the AI-based evaluations. Between the Class I and Class III malocclusion groups, there were significant variations in right mandibular body length (p < 0.001), with Class III patients exhibiting greater values. While no significant changes were identified for other characteristics, paired t-tests showed a significant divergence in mandibular body length between the right and left sides (p = 0.001). In Class III malocclusion, there was a significant preference for right deviation in the direction of mandibular deviation (p = 0.005). These results imply that AI is capable of accurately identifying some anatomical characteristics associated with face aesthetics, especially when it comes to differentiating between Class III malocclusions.In conclusion, the Saudi Arabian population's facial symmetry assessments via AI have demonstrated a high degree of reliability and consistency. Notably, the length of the mandible on the right side has emerged as a crucial feature in discriminating between malocclusion classes. The study emphasizes how AI might improve the accuracy of assessments of face aesthetics and our knowledge of facial features connected to malocclusion.

Dynamic Facial Reanimation for Facial Palsy: The Oman experience.

The goal of facial reanimation for facial palsy is to restore resting facial symmetry and dynamic facial motion that mirrors the opposite side as closely as possible. This study aimed to evaluate the restoration of oral commissure symmetry at rest and during excursion among patients with facial paralysis treated with free gracilis muscle transfer. This study included 9 patients who underwent facial reanimation with free gracilis muscle transfer at Khoula Hospital, Muscat, Oman, from 2019 to 2022. Children under 14 underwent a 2-stage surgery, while those above 14 underwent single-stage reconstruction. The average age among the cohorts was 24 years. Overall, 5 cases underwent a 2-stage facial animation, 4 underwent single-stage reconstruction and 1 patient had free flap loss following the free gracilis muscle transfer. The mean time for noticing recovery was 3 months postoperatively. Early recovery was noted in patients who underwent single-stage free gracilis muscle transfer with motor innervation from the ipsilateral nerve to the masseter compared to the cross-facial nerve transfer. Good patient satisfaction (88.9%) was observed following the procedure. This study observed earlier recovery in patients who had undergone single-stage free gracilis muscle transfer with motor innervation from the ipsilateral nerve to the masseter compared to the cross-facial nerve transfer. The oral commissure symmetry at rest and during excursion among patients with facial paralysis treated with free gracilis muscle transfer in Oman was found to be near normal.

Assessment of Facial Asymmetry in Slovak Patients with Positional Deformity

Objectives: Positional deformity (PD), also known as deformational plagiocephaly or non-synostosis, is a primary cause of abnormal head shape and asymmetry in infants. The most common type, occipital plagiocephaly, leads to flattening of one side of the back of the head or the entire head (positional brachycephaly). PD results from external forces on the growing skull, often due to childbirth and improper positioning during sleep. The incidence is approximately 1 in 300 births, with prevalence peaking between the seventh week and four months of age. Our objective was to monitor craniofacial parameters in patients with positional deformity (PD), to evaluate cranial asymmetry and PD severity, and to determine the relationship between craniofacial asymmetry and PD severity. Methods: This study included patients from the Department of Pediatric Neurosurgery at the National Institute of Children’s Diseases and the Faculty of Medicine, Comenius University in Bratislava, Slovakia. Craniofacial parameters on the right and left sides of the face were examined. Results: Significant differences were found in the upper and middle thirds of the face, indicating a strong association between positional deformity and facial asymmetry. Conclusions: the findings contribute new insights into craniofacial anthropometry and neurosurgery, enhancing the diagnosis of positional deformity in Slovakian patients.

An unusual occurrence: Treacher Collin syndrome with nasal dermoid cyst

Treacher-Collins syndrome (TCS), characterized by autosomal dominant inheritance, affects craniofacial development and presents with diverse clinical manifestations, including facial bone hypoplasia, ear malformations, and ocular abnormalities. The syndrome's association with nasal dermoid cysts is rare and poorly documented in the literature. We present a case report of a 10-year-old male with TCS who presented with a nasal dermoid cyst, a noteworthy and atypical finding within this patient population. The patient exhibited typical features of TCS, including facial asymmetry, malar and mandibular hypoplasia, and microtia. The diagnosis was confirmed through clinical evaluation and diagnostic imaging, which revealed additional anomalies such as conductive hearing loss and absence of the external auditory canal. Surgical excision of the nasal dermoid cyst was performed, utilizing the V-Y advancement glabellar flap technique for closure. This case underscores the importance of comprehensive multidisciplinary care in managing complex conditions like TCS, where treatment strategies must address both medical needs and cosmetic outcomes. Further exploration of rare associations like nasal dermoid cysts in TCS contributes to a broader understanding of the syndrome's phenotypic variability and informs optimal clinical management strategies.

Management of hemifacial microsoma with ear tags: a case report and three years follow-up

Hemifacial microsomia is a congenital disorder characterized by asymmetric facial development, affecting the ear, eye, and facial nerves. The etiology is multifactorial, involving genetic and environmental factors. Clinical manifestations can range from mild facial asymmetry to severe craniofacial deformities, often requiring multidisciplinary intervention. Physical examination for facial asymmetry and ear abnormalities. Imaging studies (CT, MRI) to assess craniofacial structures. Detailed medical history to identify any familial patterns or associated syndromes. This case underscores the importance of approach in managing Hemifacial microsomia. Multidisciplinary Long-term follow-up and staged surgical interventions are crucial for achieving optimal functional and aesthetic outcomes. Further research is needed to refine treatment protocols and improve patient quality of life.

Surgical Assisted Rapid Maxillary Expansion in Hemifacial Syndrome Patient Post Primary Cleft Treatment: A Case Report

Introduction: Cleft lip and palate is a congenital malformation resulting from an incomplete or incorrect fusion during embryonic development. Hemifacial syndrome is one of rare orofacial anomalies with midface hypoplasia. Maxillomandibular deformity repair for maxillary hypoplasia can be achieved by repositioning the maxilla and mandible to correct occlusion, mastication, functional issues, cosmetic concerns, and facial symmetry. The main concerns in the case of maxillary hypoplasia are the repair of transverse (narrowing of the maxilla), sagittal (anterior posterior), and vertical (facial proportion) aspects. This study aimed to elucidate the treatment for patients with maxillary hypoplasia by utilizing the surgical assessment of rapid maxillary expansion (SARME) following cleft lip and palate surgery. Case Report: A 21-year-old female patient had symptoms of a truncated maxilla, compromised speech, and challenges with mastication and ingestion. The patient’s surgical history includes having undergone labioplasty, palatoplasty in 2002, and gnatoplasty in 2023. The recommended treatment for this situation involves SARME. The patient’s speaking and feeding difficulties were caused by both transversal and vertical problems in the patient with maxillary hypoplasia. This is why the therapy was necessary. Case Management: Implementation of surgical assessment rapid maxillary expansion (SARME). Conclusions: This case report concludes a notable improvement in the upper and lower jaw’s functional, masticatory, and aesthetic aspects in a patient with maxillary hypoplasia. This improvement was achieved with surgical assisted of rapid maxillary expansion (SARME) following primary cleft lip and palate surgery. Keywords: Cleft lip and palate, Hemifacial syndrome, SARME

Investigation of the relationship between facial asymmetry and thoracic spine deviation

ObjectivesPrevious studies have linked facial asymmetry to scoliosis, but the relationship with thoracic vertebral deviation is unclear. This study aimed to investigate the association between facial asymmetry and thoracic spinal deviation. MethodsThis retrospective study analyzed 92 Japanese women who underwent computed tomography (CT) and plain chest X-rays for oral surgery. Cephalometric radiographs were reconstructed from CT data using SIMPLANT. Patients were categorized into symmetric and asymmetric groups based on a 2.5° deviation from the maxillomandibular (Mx-Md) midline angle. Thoracic deviation (DTh) was measured on chest X-rays, and Cobb angles were determined using the Cobb method. Multiple regression analysis explored the relationship between thoracic spine deviation and cephalometric parameters. Unpaired t-tests compared thoracic vertebrae measurements between the groups. ResultsSignificant associations were observed between DTh and several cephalometric parameters, including the Mx-Md midline angle (p = 0.011) and occlusal cant (p = 0.017) from frontal cephalometry, as well as the odontoid triangle angle and mandibular length (Co-Gn) from lateral cephalometry (R² = 0.18, p = 0.002). No significant association was found between cephalometric parameters and the Cobb angle. Of the 92 patients, 49 and 43 were included in the symmetric and asymmetric groups, respectively. The asymmetric group exhibited significantly larger thoracic deviation (p < 0.001), though no difference was observed in Cobb angle. ConclusionThe findings suggest a relationship between facial asymmetry and thoracic vertebral deviation but no significant link with scoliosis.

Preliminary application study of digital technology for constructing three-dimensional facial symmetry reference planes in anterior dental esthetic restoration

Objective: To explore the impact of digital technology in constructing a three-dimensional (3D) symmetry reference plane (SRP) for esthetic restoration of anterior teeth and to evaluate its clinical applicability. Methods: A cross-sectional study was conducted from February to May 2024, involving 20 patients [11 males and 9 females, aged (36.8±11.4) years] who underwent anterior esthetic restorations at the Department of Stomatology, People's Hospital of Ningxia Hui Autonomous Region. Symmetrical reference planes of patients' 3D facial models were constructed using three different algorithms: weighted Procrustes analysis (WPA), Procrustes analysis (PA) based on the ontology-mirror correlation method, and iterative closest point (ICP). The SRP defined by an associate chief physician served as the control (true-value group). The angular errors between each algorithm group and the true-value group were compared. The optimal algorithm was selected and combined with a three-dimensional digital smile design (DSD) to create virtual patients, followed by designing anterior restorations. The visual analogue scale (VAS) was used by patients to score the aesthetic restoration results of the conventional design (control group) and the algorithm-based design (algorithm group). Results: The angular errors of the WPA, PA, and ICP groups were 1.43°±0.66°, 1.82°±0.88°, and 4.74°±2.03° respectively, with statistically significant differences among the groups (F=41.10, P<0.001). Pairwise comparisons showed that the WPA group had significantly smaller angular errors compared to the PA and ICP groups (P<0.05). The VAS scores for aesthetic restoration were significantly higher in the algorithm group (8.09±0.74) compared to the control group (6.30±1.38) (t=-5.49, P<0.001). Conclusions: The SRP constructed using the WPA algorithm demonstrated minimal angular error when compared to the expert-defined SRP and is considered the optimal choice in clinical practice, yielding high patient satisfaction.

Evaluating Surgical Approaches for Hemimandibular Hyperplasia Associated with Osteochondroma: A Systematic Literature Review.

Background/Objectives: Hemimandibular hyperplasia (HH) associated with osteochondroma presents complex challenges in maxillofacial surgery, including facial asymmetry, occlusal instability, and temporomandibular joint (TMJ) dysfunction. Surgical interventions vary widely in approach and outcomes, underscoring the need for a systematic evaluation of effectiveness. This systematic review assesses the effectiveness of surgical approaches for managing HH associated with osteochondroma, focusing on techniques including condylectomy, orthognathic surgery, distraction osteogenesis, total joint replacement (TJR), and genioplasty. Methods: Following PRISMA 2020 guidelines, a comprehensive search was conducted in PubMed, Scopus, and Web of Science for studies published from 2000 to 2023. Eligibility criteria were based on the PICO framework, with primary outcomes evaluated for facial symmetry, occlusal correction, mandibular function, and recurrence rates. The Cochrane Risk of Bias Tool assessed study quality, while the GRADE framework evaluated the certainty of evidence. This review was not registered due to exclusion criteria for certain dental topics in PROSPERO. Results: Of 145 studies identified, 18 met inclusion criteria, totaling 214 patients. High and low condylectomy both effectively corrected asymmetry, with high condylectomy reducing recurrence risk but often requiring reconstruction. Orthognathic surgery, combined with condylectomy, significantly enhanced facial symmetry and occlusal function. Distraction osteogenesis proved valuable for mandibular lengthening in cases of severe deformities, while TJR offered definitive solutions for extensive joint involvement. Genioplasty corrected chin asymmetry, contributing to improved facial balance. Limitations included small sample sizes and variable follow-up durations. Conclusions: Surgical approaches tailored to individual patient needs show effectiveness in treating HH associated with osteochondroma, achieving functional and esthetic outcomes. Future studies should prioritize larger cohorts and standardized follow-up protocols to better assess long-term efficacy. Advances in 3D surgical planning and individualized treatment strategies show promise for optimized patient-specific care.

Mandibular Actinomyces Osteitis Associated with Florid Cemento-Osseous Dysplasia

Introduction: Actinomycosis is a rare chronic suppurative granulomatous infection caused by actinomyces. The Florid cemento-osseous dysplasia (FCOD) is a benign fibro-osseous lesion. We report a case of simultaneous association of these two entities with the use of PRF for the first time in this context. Case Report: A 59-year-old female with no medical history was received in our clinic for painful swelling on the right mandible. On clinical examination, we noticed a facial asymmetry caused by the swelling and bone exposure with pus on the right mandibular ridge. The panoramic radiography showed right and left posterior mandibular opacities. On the cone beam reconstructions, we noted a hyperdense posterior right mandibular image surrounded by a hypodense border and a hyperdense posterior left mandibular image surrounded by a hypodense border, in contact with the apices of tooth 36. Based on the clinical, radiographic and pathological findings, the present case was diagnosed as mandibular actinomyces osteitis associated with florid cemento-osseous dysplasia. The treatment consisted of surgical excision of the lesion, filling of the defect with PRF and prescription of antibiotics. Conclusion: Despite its rarity, practitioners should be aware of the possibility of the coexistence of these two entities simultaneously. Thus, they can initiate the appropriate treatment.

Botulinum Toxin Type A for Trigeminal Neuralgia: A Comprehensive Literature Review.

Trigeminal neuralgia is a neuropathic pain syndrome responsive to botulinum toxin type A therapy. This review had the goal of analyzing the different studies published from 2002 to January 2024 to better define the techniques and the types of botulinum toxin type A used, the doses, the injection routes, and the different populations of trigeminal neuralgia patients treated. We considered only articles in which the therapy was administered to humans to treat trigeminal neuralgia. Case reports, case series, open-label, retrospective, and RCT studies were considered. The research was conducted on MEDLINE and the keywords included (trigeminal neuralgia) and (botulinum). Thirty-five articles were considered suitable for this review. Botulinum toxin type A was shown to be an effective therapy for TN pain in all the articles analyzed, albeit there is a lack of standardization in methods and outcomes. The techniques, the doses, and the injection approaches were very heterogeneous among the studies. Only two botulinum toxin type A formulations have been used in this setting: onabotulinumtoxinA and lanbotulinumtoxinA. There were 300 patients treated with onabotulinumtoxinA and 760 treated with lanbotulinumtoxinA overall (in 42 patients, the formulation was not specified). The distinction between etiological and clinical types of TN has been made by only a small portion of the studies. The main adverse event was transient facial asymmetry. Botulinum toxin type A is indeed a promising therapy that is clearly effective for trigeminal neuralgia. OnabotulinumtoxinA is the most common formulation used in Western countries; however, the meager sample of TN patients treated, and the lack of standardization are not sufficient for this therapy to be approved by the FDA or EMA. Indeed, more studies with standardized methods and larger samples are needed for this purpose.

Laser therapy for Bell's palsy: a systematic review and meta-analysis of randomized trials.

This meta-analysis investigated therapeautic effects of laser therapies in patients with Bell's palsy (BP). The authors performed the literature search in the PubMed, Embase, and Cochrane Library databases using the following search terms: (facial paralysis OR Bell's palsy OR facial palsy OR idiopathic facial paralysis) AND (laser OR low-level laser OR photobiomodulation OR phototherapy). Relevant studies published before October 29th 2024 were identified. Randomized trials comparing the outcomes of laser therapies with other interventions, including electrical stimulation and control or usual care in patients with BP were included. The mean difference (MD) was determined as the effect size for continuous outcomes, and outcome accuracy was determined using 95% confidence intervals (CIs). Twelve studies were included, with a total of 597 patients. Nine studies were further included in the quantitative analysis. Our meta-analysis revealed that laser therapy significantly improved disease severity (House-Brackmann facial paralysis scale) (MD = -1.51, 95% CI = -2.43 to -0.59), facial asymmetry (Sunnybrook facial grading system) (MD = 20.63, 95% CI = 10.33 to 30.94), and facial function and disability (Facial disability index) (MD = 17.91, 95% CI = 5.60 to 30.22) when compared with control care in adult patients. Moreover, laser therapy significantly improved facial severity (MD = 21.05, 95% CI = 16.77 to 25.33) when compared with electrical stimulation. In addition, no adverse effects of laser therapy were reported. Laser therapy has favorable effects on disease severity, facial asymmetry, and facial function and disability for patients with BP.

Comparison of Different 3D Surface Registration-Based Methods to Assess Facial Asymmetry.

Facial asymmetry is gaining an increasing diagnostic interest in many clinical contexts. Several three-dimensional surface-based methods have been proposed for its assessment; however, they might provide non-equivalent data. Since there is a lack of comparative studies in these terms, this study aims to compare three methods for assessing the asymmetry of the face and facial thirds, thus addressing whether the potential differences can be considered clinically acceptable or not. Two 'maxillofacial' methods based on the trigeminal nerve distribution and one 'orthodontic' method based on reference horizontal planes were used to identify the facial thirds on 3D facial models of 80 Italian healthy adults to calculate the asymmetry of the face, and the upper, middle, and lower thirds of the face differently selected by each method. As a measure of asymmetry, the Root Mean Square value was calculated through a mirroring surface-based registration. Intra- and inter-operator reliability was verified for each method. Differences and interchangeability between the methods were tested, respectively, by two-way repeated measures ANOVA (Analysis of Variance) and Bland-Altman and Similarity Percentage model analysis. Additionally, the time required to perform each method was assessed. All methods demonstrated excellent intra- and inter-operator reliability. While the ANOVA analysis found significant differences (p < 0.001) for the majority of facial Regions of Interest between each method, the Bland-Altman analysis revealed that the differences were clinically acceptable (<0.50 mm) for all facial regions between the trigeminal methods, and for the face and the upper third of the face between the orthodontic method, which was revealed to be faster, and the trigeminal ones. The additional similarity percentage model provided visual support for the complete interchangeability of the two trigeminal methods, as evidenced by the lower Coefficient of Variation value. There is no best method for assessing facial asymmetry that applies to all types of clinical settings, as we have shown that different methods may not be completely interchangeable. However, we suggest that the methods based on the trigeminal subdivision can be used interchangeably in contexts where the morpho-functional analysis of maxillofacial regions with different embryological origins is considered. Thus, the clinical setting imposes the choice of one method over another and, as we have pointed out, the consequent comparison of data with those obtained with methods whose interchangeability has been demonstrated.

Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis: evidence from facial grading and automated image analysis

Surface Functional Electrical Stimulation (FES) is a well-studied intervention for multiple muscular disorders. However, it is still controversially discussed as a complementary therapy for complete facial paralysis. The aim of this intervention is to test a daily home-based ES concept as a pilot study regarding safety, feasibility, and effects on facial functionality and symmetry. In a prospective single-centre pilot study, 10 patients (median 61 years, denervation 130 d) with complete peripheral facial paralysis performed home-based FES of the affected lateral mouth region Stimulation parameters, facial paralysis scores and standardised photographs were assessed in monthly follow-ups. No serious adverse events appeared. Stimulation parameters could be constantly increased indicating effective muscle training while subjectively perceived functionality of the face improved. Thus, smile angle of the paralysed side improved as well. FES is a safe therapy model for application in facial nerve paralysis patients. A feasible stimulation protocol could be applied, which improved the functionality and symmetry of the stimulated facial region. A future controlled, randomised and double-blind follow-up study is needed to investigate these initial results in a further evolved replicable setting.

Improving life quality via mandibular reconstruction: Innovations and techniques – A literature review

Mandibular abnormalities can arise from a range of causes, including illnesses, trauma to the face, and surgical excision of tumors. These conditions can significantly affect daily activities such as eating, speaking, and even grooming. These functions are impaired without appropriate repair, which has a major negative impact on an individual's quality of life. Mandibular reconstruction aims to preserve facial symmetry and allow patients to regain their normal ability to chew food by restoring both the structure and functionality of the jaw. A successful restoration also takes into account elements such as the positioning of implants to restore oral function and, in certain cases, the reconnecting of the inferior alveolar nerve to enhance feeling.Mandibular reconstruction has undergone a revolutionary change in technique over the years. These developments are still ongoing, with the goal of improving patient recovery and outcomes. This article highlights the continuous attempts to improve surgical techniques and integrate new technologies for improved patient care. It gives a general review of the historical evolution, contemporary approaches, and prospective future possibilities in mandibular reconstruction.

The Correlation Between Static and Dynamic Facial Asymmetry in Unilateral Cleft Lip and Palate.

Assess the relationship between static and dynamic facial asymmetry in unilateral cleft lip and palate during maximum smile. Retrospective cross-sectional study. Multidisciplinary dentofacial planning clinic. Thirty-one surgically managed non-syndromic unilateral cleft lip and palate patients between the ages of 13 to 17 years. Dynamic three-dimensional (3D) facial images (four-dimensional [4D]) throughout the course of a maximum smile were captured using video stereophotogrammetry at a rate of 60 frames per second, which generated 180 3D images/expression. A generic facial mesh containing more than 7000 vertices was superimposed onto the 3D facial images to quantify and track facial asymmetry throughout the captured sequence. Partial ordinary Procrustes analysis was utilized to calculate an asymmetry score at the rest position, maximum smile, and at the point of maximum mathematical asymmetry. The relationships between the asymmetry at rest and the asymmetry at the point of maximum smile (static 3D), and the maximum mathematical asymmetry (dynamic 4D) were evaluated. Asymmetry scores were higher at maximum smile than at rest. Maximum mathematical asymmetry was observed in most cases during the relaxation phase. Static asymmetry at rest and maximum smile was strongly correlated with the maximum mathematical asymmetry (r = 0.941, P < .001). Static 3D asymmetry at both rest and maximum smile are strongly correlated with dynamic 4D facial asymmetry. The use of 4D imaging, combined with generic mesh conformation and dense correspondence analysis, provides a valid objective measure of facial asymmetry.

Computer-assisted contouring combined with bone ostectomy for dental implant placement of craniofacial fibrous dysplasia involving the right maxilla.

Craniofacial fibrous dysplasia (CFD) affecting the jaws can result in facial asymmetry, posing a unique challenge for dental implant placement in edentulous areas. This case report introduces an innovative approach for rehabilitating the posterior maxilla affected by CFD using a computer-guided technique for maxillary recontouring and substitution bone grafting at implant sites. A 58-year-old edentulous female with a craniofacial fibrous dysplasia bone lesion affecting the right maxilla was referred for correction of asymmetry and dental implant placement. A computer guide was devised for shaving and contouring the right maxilla. Following virtual maxillary reduction, a second guide was created over the osteomized 3D model to plan the location of future dental implants and guide bone ostectomies for allograft substitution. Particulate bone substitute was applied to ostectomy sites in the affected maxillary alveolar ridge. Four implants were placed successfully four months post-operation, with integration confirmed by clinical examination after one year of follow-up. This treatment approach emerges as a reliable and effective modality for simultaneous dental implant rehabilitation in edentulous alveolar bone and jaw contouring in CFD cases.

Effect of Facial Acupuncture Stimulation: Magnetic Resonance Imaging-Based Masseter Muscle Volume Analysis and Questionnaire Evaluation

Abstract Background Cosmetic acupuncture may improve wrinkles, swelling, sagging, and facial asymmetry and may lift facial contours. Objectives To investigate the impact of cosmetic acupuncture on masseter muscle volume and its implications for facial aesthetics Methods We included 10 apparently healthy adult women (average age, 50.3 ± 6.45 years) and performed acupuncture once a week for 8 weeks. Magnetic resonance imaging was conducted before acupuncture stimulation and 3 days after the treatment. The collected image data were analyzed using ZioCube software (ZioSoft Co., Ltd., Tokyo). Before and after the intervention, two evaluators measured the masseter muscle volume thrice each and calculated the average value. Results The average total volume of the left and right masseter muscles decreased from 40.73 ± 8.2 cm3 to 37.81 ± 8.57 cm3 after cosmetic acupuncture, a significant reduction of 2.92 ± 2.48 cm3 (7.37%, p &amp;lt; 0.05). All 10 subjective evaluation items showed significant decreases, particularly in facial sagging, contour, and asymmetry, confirming aesthetic improvements and psychological satisfaction among participants. Cosmetic acupuncture reduced masseter muscle volume, leading to noticeable aesthetic benefits. Conclusions Acupuncture stimulation at acupoints around the masseter muscle can reduce the muscle volume due to muscle relaxation. The improvement in subjective evaluation and changes and decreases in masseter muscle shape enable the attainment of facial contour aesthetics, contributing to the evidence in support of cosmetic acupuncture.

Successful Management of Parry-Romberg Syndrome With Lipografting: A Case Report

Parry-Romberg Syndrome (PRS), or progressive hemifacial atrophy, is a rare disorder marked by the progressive atrophy of skin and soft tissues, sometimes affecting muscles, cartilage, and bones. Typically manifesting in childhood, PRS has a 66% female predilection and sporadic occurrence. Diagnosis is clinical, supplemented by tests to exclude other conditions. Treatment options include bone/cartilage grafts, fat grafts, dermal fillers, and free tissue transplantation. Lipoinjection, using autologous adipose tissue enriched with stem cells, is a promising technique. A 33-year-old female with PRS exacerbated by pregnancy presented with severe right hemifacial atrophy. Initial lipoinjection elsewhere resulted in significant graft reabsorption. At our institution, a second lipoinjection was performed at age 34 after disease remission. Five months postoperatively, 30% graft reabsorption was noted, but significant improvement in facial symmetry was achieved. A second lipoinjection session further enhanced facial volume and skin quality. Four months postoperatively, the patient showed substantial improvement, with 90% facial symmetry and stable disease remission. Autologous lipoinjection is an effective treatment for PRS-related facial atrophy, offering minimal tissue rejection and satisfactory aesthetic outcomes. The presented case highlights the potential of this technique in achieving significant clinical improvement and facial symmetry in PRS patients.

Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance.

We introduce an open-source, semi-automated pipeline to detect abnormally asymmetric phenotypes in 3D scans of fetal mice to explore the relationship between facial asymmetry, perturbed development, and developmental instability.