The investigation of electromagnetohydrodynamic (EMHD) flow of non-Newtonian fluids in microchannels represents a compelling intersection of fluid dynamics, electromagnetism and materials science, particularly demonstrating significant potential and importance in contemporary microfluidic applications. This work delves into the intricate mechanisms governing the EMHD flow of non-Newtonian Jeffrey fluids within parallel plate microchannels, with a specific focus on the influence of asymmetric slip boundary conditions that depend on surface charge. The EMHD flow is propelled by the amalgamation of the Lorentz force and a consistent pressure gradient. Analytical solutions for the velocity and volumetric flow rate of this problem are derived employing both the method of separation of variables and Cramer's rule. Initially, this study undertook comparisons with prior research, leveraging pertinent assumptions to validate the precision of our findings. Subsequently, the discussion shifts to the examination of how velocities are affected by surface charge effects under various slip boundary conditions at different Reynolds numbers. The results suggest that velocities are significantly influenced by surface charge effects under asymmetric slip boundary conditions compared to scenarios involving symmetric and single-wall type, irrespective of the Reynolds number, thereby highlighting the importance of this study. Finally, the relationships among key parameters such as surface charge density, Hartmann number, relaxation time and retardation time affecting volumetric flow rate are analyzed, while approaches and specific percentages for increasing or decreasing volumetric flow rate are provided. One of the more interesting findings is that the volumetric flow rate is expected to experience a 3.9% reduction, considering the influence of the surface charge effect. These findings are not only vital for advancing microfluidics but also have the potential to drive new innovations in related medical technologies, given the notable similarities in the physical properties of Jeffrey fluid and blood.