Association Of Thrombocytopenic Purpura Research Articles

P0357 A CASE OF THROMBOTIC THROMBOCYTOPENIC PURPURA ASSOCIATED WITH CLOPIDOGREL

P0357 A CASE OF THROMBOTIC THROMBOCYTOPENIC PURPURA ASSOCIATED WITH CLOPIDOGREL

Cerebellar degeneration and immune thrombocytopenic purpura associated with human immunodefi ciency virus infection (HIV)

Cerebellar disorders associated with HIV infection are usually caused by opportunistic infections, central nervous system lymphoma, and toxic effects of medicines, nutritional and metabolic disorders, and cerebrovascular disease. We present an unusual association of cerebellar degeneration and immune thrombocytopenic purpura in a 28-years-old woman HIV infected. An autoimmune aetiology is likely.

Maladie de Basedow et purpura thrombopénique auto-immun : l'évolution n'est pas toujours parallèle

The association of idiopathic thrombocytopenic purpura and Graves' disease is rare. Hence, little is known about the outcomes of these two diseases when associated. We report two cases of idiopathic thrombocytopenic purpura associated with Graves' disease, in which the two diseases had distinct outcomes. Thus, the hypothesis of cross-reaction between antithyroid antibodies and platelet epitopes, which has been proposed to explain the association, seems unlikely.

A Newborn Who Has a Swollen Upper Extremity

A term male newborn presents with a swollen left upper extremity. ### Prenatal History: ### Birth History and Presentation: The infant was delivered from vertex presentation by spontaneous vaginal delivery. A pediatric team was not present at the delivery because there were no risk factors. Delivery was complicated by left shoulder dystocia. Because the labor and delivery nurse noted that the infant had poor tone and respiratory effort, he received positive pressure ventilation with bag and mask for approximately 1 minute, and the pediatric team was called. Apgar scores were 3 at 1 minute and 7 at 5 minutes. The birthweight was 3.7 kg. What other physical examination findings are pertinent? What laboratory tests would you order? What interventions are indicated? ### Vital Signs: ### Physical Examination: #### Photograph of infant's body The patient was started on oxygen by nasal …

Thrombotic Thrombocytopenic Purpura Associated with Transient Chromosomal Aberrations: Successful Treatment with Plasma Exchange

A 69-year-old woman with typical thrombotic thrombocytopenic purpura is reported, who was treated successfully by plasma exchange. An initial chromosomal analysis of peripheral blood lymphocytes revealed abnormal patterns of 45, XO/46, XX/47, XXX; a second analysis showed 45, XO/46, XX/47, XXX/47, XX + 21, and a third, performed in remission, showed a normal pattern. Skin fibroblasts showed a normal pattern even during the acute disease. The association of transient chromosomal aberrations and thrombotic thrombocytopenic purpura might be related to a viral infection.

Thrombocytopenic purpura in narcotics addicts.

Since November 1982 we have seen an association of thrombocytopenic purpura with chronic narcotic addiction in 70 patients with a mean platelet count of 53000 +/- 4000 (SE); 33 had stopped taking intravenous drugs for an average of 21.2 +/- 4.7 months; 13 of 15 had elevated antibody titers for a virus related to the acquired immunodeficiency syndrome. Platelet-bound IgG, IgM, and complement levels were 16.7-, 5.6-, and 3.1-fold greater than control values, respectively, and 2.6-, 1.9-, and 2.4-fold greater than values in 25 patients with classic autoimmune thrombocytopenic purpura studied at the same time. Thirty-three of thirty-six addicts had elevated circulating immune complexes, whereas 8 patients with autoimmune thrombocytopenia had no elevation. Eleven of eighteen addicts had positive serum platelet-reactive IgG titers, compared to 5 of 19 patients with classic autoimmune thrombocytopenia. The platelet-reactive IgG in sera of addicts was composed of 7S IgG antibody as well as high molecular weight (immune complex) IgG. Thus, chronic addicts appear to have a new immunologic platelet disorder associated with the presence of 7S IgG antiplatelet antibody, like patients with classic autoimmune thrombocytopenic purpura, and immune complex associated nonspecific platelet IgG, like male homosexual patients with thrombocytopenia.

Acute thrombocytopenic purpura associated with "Septrin".

Medical Journal of AustraliaVolume 1, Issue 14 p. 769-770 Correspondence ACUTE THROMBOCYTOPENIC PURPURA ASSOCIATED WITH “SEPTRIN” First published: 01 April 1971 https://doi.org/10.5694/j.1326-5377.1971.tb87850.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume1, Issue14April 1971Pages 769-770 RelatedInformation

THROMBOCYTOPENIC PURPURA ASSOCIATED WITH HYDROCHLOROTHIAZIDE THERAPY

Chlorothiazide and hydrochlorothiazide are widely used, effective, orally given nonmercurial diuretic and antihypertensive agents. A principal action of these drugs is marked enhancement of the excretion of sodium and chloride and to a lesser extent of potassium. Although they possess the advantage of being relatively safe drugs, there are a few sidereactions of importance, including nausea, skin rash, anorexia, headache, restlessness, and constipation. Potentially serious side-effects include postural hypotension; circulatory collapse; sodium, potassium, and chloride depletion; temporary aggravation of hyperuricemia; and acceleration of hepatic coma in patients with severe liver disease. 1 Two cases of purpura with thrombocytopenia due to administration of chlorothiazide (Diuril) have recently been reported. 2 Among a group of patients treated with hydrochlorothiazide a case of thrombocytopenia with purpura presumed to be due to administration of this drug was encountered and is here described. The problem of purpura was complicated by adynamic ileus secondary to hypopotassemia.

Thrombocytopenic purpura occurring with large hemangioma.

THE ASSOCIATION of thrombocytopenic purpura with large hemangiomas has been reported in seven infants.* Management of this condition has consisted of irradiation of the hemangioma, blood transfusions, and, in two cases, splenectomy. One author 6 states that splenectomy was probably not effective as a treatment of the thrombocytopenia in this syndrome. We wish to report a case in which splenectomy was followed by complete regression of the thrombocytopenia and hemangioma. REPORT OF A CASE A one-month-old white boy was admitted on April 17, 1953. He was born at full term, and delivery was spontaneous. The mother was normal and the pregnancy uncomplicated. His birth weight was 7 lb. 2 oz. The only abnormality noted at birth was a bluish discoloration, 2½ in. in diameter, involving the skin over the right deltoid area. Circumcision was performed two days after birth without abnormal bleeding. At 2 weeks of age the lesion on

THROMBOCYTOPENIC PURPURA ASSOCIATED WITH OXYTETRACYCLINE THERAPY

THROMBOCYTOPENIC PURPURA ASSOCIATED WITH OXYTETRACYCLINE THERAPY

Thrombocytopenic purpura associated with cat-scratch disease; response of cat-scratch disease to steroid hormones.

IT IS THE purpose of this paper to report the occurrence of thrombocytopenic purpura during typical cat-scratch disease and the probable relationship of the two conditions. This association has not previously been noted in the literature. It is the further purpose of this paper to note the salutory effects of corticotropin (ACTH) and cortisone on the lymphadenopathy of cat-scratch disease, another fact not previous reported. REPORT OF A CASE A 26-year-old grade school teacher was admitted to the hospital on Jan. 27, 1953. Five weeks before admission he had been scratched on the tip of the fourth finger of his right hand by his cat. After several days the scratch began to swell, and a few days later the patient noted painful swelling of a right axillary lymph node, followed in one week by painful swelling of a right epitrochlear lymph node. During this period the patient felt fatigued, ached