You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology II1 Apr 2017MP81-10 ERECTILE DYSFUNCTION IN 45–YEAR–OLD GERMAN MEN IN ASSOCIATION WITH RISK FACTORS AND COMORBIDITIES; RESULTS OF THE GERMAN MALE SEX–STUDY Kathleen Herkommer, Jacqueline Hallanzy, Martina Kron, F.-M. Köhn, Maximilian Schmautz, Peter Albers, Christian Arsov, Boris A. Hadaschik, Markus Hohenfellner, Florian Imkamp, Martin Kuczyk, and Jürgen E. Gschwend Kathleen HerkommerKathleen Herkommer More articles by this author , Jacqueline HallanzyJacqueline Hallanzy More articles by this author , Martina KronMartina Kron More articles by this author , F.-M. KöhnF.-M. Köhn More articles by this author , Maximilian SchmautzMaximilian Schmautz More articles by this author , Peter AlbersPeter Albers More articles by this author , Christian ArsovChristian Arsov More articles by this author , Boris A. HadaschikBoris A. Hadaschik More articles by this author , Markus HohenfellnerMarkus Hohenfellner More articles by this author , Florian ImkampFlorian Imkamp More articles by this author , Martin KuczykMartin Kuczyk More articles by this author , and Jürgen E. GschwendJürgen E. Gschwend More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2536AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We analyzed erectile dysfunction (ED) in a representative sample of 45-year-old German men and assessed the association with lifestyle risk factors and ED-related comorbidities. METHODS Data was collected within the German Male Sex-Study (part of the PROBASE prostate cancer screening trial) between April 2014 and April 2016. 45-year old men living in four German regions (Dusseldorf, Hannover, Heidelberg, Munich) were invited within a screening trial. 10.135 Caucasian, heterosexual and sexually active men were included in this analysis. An anamnesis interview was obtained for all men including information on comorbidities and medication. Weight and waist circumference were measured on site. Erectile function was evaluated using the International Index of Erectile Function (IIEF-EF(6)). The presence of ED was defined as IIEF-EF-Score <=25. Association of ED and comorbidities/risk factors were analyzed by logistic regression. RESULTS The prevalence of ED was 25.2% (IIEF-EF: 6-10: 3.1%, 11-16: 9.2%, 17-21: 4.2%, 22-25: 8.7%). We ascertained a baseline risk of 14.4% for men without ED-related comorbidities and with healthy lifestyle factors: no smoking, waist circumference <94cm, physical activity >=4 days a week, IPSS=0. In multiple logistic regression with backward elimination the following factors associated with ED were identified: Comorbidities: Depression [OR 1.87], lower urinary tract symptoms (defined as International Prostate Symptom Score >7) [OR 1.68], diabetes mellitus [OR 1.38], hypertension [OR 1.22].Risk factors: Poor general health status (first question of SF12) [OR 1.72], waist circumference (>=102cm) [OR 1.31], physical activity (<2 days a week minimum 30 minutes per day mild exercise) [OR 1.27], smoking regularly [OR 1.15]. The only factor eliminated during variable selection was BMI even though this factor showed a crude OR of 1.42. ED-prevalence increased with the number of risk factors (0 factors: 21.9%; 3 factors: 33.4%) and number of comorbidities (0 comorbidities: 22.4%; 3-4 comorbidities: 64.3%). CONCLUSIONS ED was found in every fourth 45-year-old German man. Prevalence increased significantly with the number of risk factors and comorbidities. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1092-e1093 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Kathleen Herkommer More articles by this author Jacqueline Hallanzy More articles by this author Martina Kron More articles by this author F.-M. Köhn More articles by this author Maximilian Schmautz More articles by this author Peter Albers More articles by this author Christian Arsov More articles by this author Boris A. Hadaschik More articles by this author Markus Hohenfellner More articles by this author Florian Imkamp More articles by this author Martin Kuczyk More articles by this author Jürgen E. Gschwend More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...