Ramp controllers are required to manage their workloads effectively while handling complex operational tasks, a crucial part of improving aviation safety. The ability to detect their instantaneous workload is vital for ensuring operational effectiveness and preventing hazardous incidents. This paper introduces a novel methodology aimed at enhancing the evaluation of the ramp controller’s cumulative workload by incorporating and optimizing the feature combination from eye movement, respiratory, and fatigue characteristics. Specifically, a 90-minute simulated experiment related to ramp control tasks, using real data from Shanghai Hongqiao Airport, is conducted to collect multi-type data from 8 controllers. Following data construction and the extraction of multi-type, the workloads of all samples are categorized through unsupervised learning. Subsequently, supervised learning techniques are used to calculate feature weights and train classifiers after data alignment. The optimal feature combination is established by calculating feature weights, and the best classification accuracy is over 98%, achieved by the KNN classifier. Furthermore, numerical evaluation and threshold calculations for different workload levels are interpreted. It is promising to provide insights into future works towards human-centered data construction, processing, and interpretation to promote the progress of workload assessment within the aviation industry.