Soil erosion and sediment buildup are the factors that speed up the decline in capacity and function of reservoirs, agricultural products, and water resources. In order to simulate sediment and runoff and map high sediment-yielding sub-basins in the Gibe Gojeb catchment in southwest Ethiopia, this study used the Soil and Water Assessment Tool (SWAT) model. Using data on sediment and river flow, calibration and validation were carried out. Between 2003 and 2016, the catchment produced an average annual sediment loading of 62.5 tons ha−1 yr−1, with loading fluctuations ranging from 0.2 to 108.4 tons ha−1 yr−1. The acceptable sediment yield threshold value ranges from 12.3 to 108.4 tons ha−1 yr−1 for 56 sub-basins, and from 0.2 to 10 tons ha−1 yr−1 for 5 sub-basins. The most significant sub-basins with very high to extremely severe sediment yields were sub-basins 1 to 30, 32 to 44, 47, 48, 50, 51, and 53 to 61. After thirteen years of operation, the yearly amount of 58,802 tons of sediment transferred from the catchment and deposited into Gibe One reservoir has decreased the capacity by 5.7 %. The accumulation of sediment in a reservoir has an impact on its functionality, power production, and capacity, affecting the safety of dams and the environment. The study's findings enhanced our comprehension of sediment accumulation in reservoirs and furnished us with the necessary information regarding reservoir safety, integrated soil, and water management.