Objective To evaluate the clinical usefulness of assessing transcranial magnetic stimulated motor evoked potentials (MEP) in lumbar spinal stenosis (LSS).Methods Twenty-three LSS patients, consisting of 12 males and 11 females were enrolled.The mean age was 67.9 years(52-83 years).The average duration of symptoms was 31.5 months(3 months to 10 years).Twelve patients were associated with degenerative spondylolisthesis.Fourteen patients had bilateral and 9 patients had unilateral leg symptoms.The number of involved disc levels was one in 15 cases, two in 7 cases and three in 1 case.All patients were associated with neurogenic intermittent claudication (NIC).The mean walking distance of NIC and the minimal cross-sectional area (mCSA) of the dural sac was 302.1 m and 0.4 cm2, respectively.The preoperative data of MEP latency (MKPLT) recorded in both sides of adductor hallucis (AH), clinical symptoms, Japanese Orthopaedic Association (JOA) scores for low back pain, visual analogue scale (VAS) for back pain, leg pain and numbness were evaluated.Results The mean MEPLT were (42.1±2.8) ms.The mean JOA score, VAS scores for back pain, leg pain and numbness were 15.9±4.8, 6.0±2.9, 7.7±1.9 and 7.3±3.0, respectively.MEPLT was related to the walking distance (r=-0.455, P<0.05), limb symptoms (bilateral or unilateral symptoms, r=0.545, P<0.05) and VAS-numbness (r=0.605, P<0.05), but was not related to diagnosis (with/without degenerative spondylolisthesis), affected disc levels, duration of symptoms, JOA scores, VAS for back pain and leg pain.MEPLT was significantly delayed in patients who showed a walking distance less than 500 m (P<0.05).Conclusion MEP is useful in LSS assessment.It can reflect the subjective severity of motor disturbance and predict the neurological deficit prior to appearance. Key words: Lumbar vertebrae; Spinal stenosis; Evoked potentials, motor