Aryl Aluminum Research Articles

Ligand-Free, Copper-Catalyzed Coupling Reaction of Aryl Aluminum Reagents with N-Aryl Thiosuccinimides

: A highly efficient and simple cross-coupling reaction of N-aryl aluminum reagents with Naryl thiosuccinimides for the synthesis of diarylsulide derivatives using CuCl (20 mol%) as a catalyst is reported. Under the optimum reaction conditions, the coupling reaction between aryl aluminum reagents with different substituents and N-aryl thiosuccinimides with different substituents can be carried out smoothly with 18-94% isolated yields of diarylsulides. The method avoids the use of expensive transition metals, such as Pd, Ir, or Rh, phosphine ligands, and has the advantages of simple operation and high reaction efficiency. The structures of all the target compounds are confirmed by 1HNMR and 13CNMR.

The Influence of Metal Lithium and Alkyl Chain in the Nucleating Agent Lauroyloxy-Substituted Aryl Aluminum Phosphate on the Crystallization and Optical Properties for iPP

In this work, a kind of aryl phosphate salt nucleating agent (APAl-12C) was synthesized, which was replaced in the hydroxyl group on the aluminum hydroxy bis [2,2′-methylene-bis(4,6-di-tert-butylphenyl) phosphate] (APAl-OH) by lauroyloxy, which could improve the dispersion between the nucleating agent and the iPP matrix and reduce the migration potential of the nucleating agent in the iPP matrix by increasing the molecular weight. The structure of the nucleating agent APAl-12C was analyzed by fourier infrared spectroscopy (FT-IR ) and 1H NMR. The differential scanning calorimeter (DSC) results indicated that the addition of APAl-OH or APAl-12C alone was inferior to the commercial nucleating agent NA-21 (compounds of APAl-OH and Lithium laurate) in terms of the crystallization behavior, which may be due to the importance of metal Li in the crystallization property. Thus, the iPP/A12C-Li composites were prepared with APAl-12C, lithium laurate (lilaurate) and the iPP matrix. The crystallization behavior, morphology, optical and mechanical properties for the iPP/A12C-Li composites were systematically studied and compared with that of the iPP/NA-21 composite. Among the iPP/A12C-Li composites with the addition of 0.5 wt%, APAl-12C/Lilaurate had the fastest crystallization rate and reduced the haze value of the neat iPP from 36.03% to 9.89% without changing the clarity, which was better than that of the iPP/NA-21 composite. This was due to the weakening of the polarity of the APAl-12C after lauroyloxy substitution and better dispersion in the iPP matrix, resulting in a significant improvement in the optical properties.

ChemInform Abstract: Generation of Functionalized Aryl and Heteroaryl Aluminum Reagents by Halogen—Lithium Exchange.

AbstractVarious functionalized aryl aluminum reagents are obtained by performing halogen—Li exchange reactions with the corresponding aryl halides in the presence of iBu2AlCl.

ChemInform Abstract: Iron‐Catalyzed Cross‐Coupling of Halohydrins with Aryl Aluminum Reagents: A Protecting‐Group‐Free Strategy Attaining Remarkable Rate Enhancement and Diastereoinduction.

AbstractThe cross‐coupling reaction of protected trans‐4‐chlorocyclohexanol derivatives with in situ formed aryl aluminum reagents proceeds with low diastereoselectivity whilst analogous reactions of unprotected trans‐4‐chlorocyclohexanol demonstrate a good trans‐selectivity.

ChemInform Abstract: Copper‐Catalyzed Asymmetric Conjugate Addition of Aryl Aluminum Reagents to Trisubstituted Enones: Construction of Aryl‐Substituted Quaternary Centers.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract: Enantioselective Synthesis of All‐Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five‐, Six‐, and Seven‐Membered‐Ring β‐Substituted Cyclic Enones.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Copper‐Catalyzed Asymmetric Conjugate Addition of Aryl Aluminum Reagents to Trisubstituted Enones: Construction of Aryl‐Substituted Quaternary Centers

Copper‐Catalyzed Asymmetric Conjugate Addition of Aryl Aluminum Reagents to Trisubstituted Enones: Construction of Aryl‐Substituted Quaternary Centers

Copper‐Catalyzed Asymmetric Conjugate Addition of Aryl Aluminum Reagents to Trisubstituted Enones: Construction of Aryl‐Substituted Quaternary Centers

Al be back: Novel aryl and alkenyl aluminum reagents are generated through a halogen/Li exchange–Li/Al transmetalation sequence. These aryl alanes are used in the copper-catalyzed asymmetric conjugate addition reaction to a variety of cyclic enones giving chiral aryl-substituted quaternary centers (see scheme). Both, electron-donating and electron-withdrawing groups give full conversion and very good ee values.

Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring beta-substituted cyclic enones.

Enantioselective synthesis of all-carbon quaternary stereogenic centers by catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents to five-, six-, and seven-membered-ring beta-substituted cyclic enones.

Enantioselective Synthesis of All‐Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five‐, Six‐, and Seven‐Membered‐Ring β‐Substituted Cyclic Enones

Effiziente katalytische Verfahren für asymmetrische konjugierte Additionen von Alkyl- und Arylaluminiumreagentien an nichtaktivierte β-substituierte Cyclopentenone (siehe Schema) werden durch Kupferkomplexe chiraler zweizähniger N-heterocyclischer Carbene vermittelt (z. B. aus 1) und führen zu quartären Kohlenstoffstereozentren.

ChemInform Abstract: Dichlorobis(triphenylphosphine)nickel-catalyzed Cross-Coupling of Aryl Chlorides with Intramolecularly Stabilized Group 13 Metal Alkylating Reagents.

Abstract The intramolecularly stabilized alkyl and aryl aluminum complexes 1 , 4 and 11 , as well as the indium compounds 6 , 9 and 10 cross-couple with a variety of chloroarenes at 80°C in the presence of NiCl 2 (PPh 3 ) 2 to give selectively the respective alkylated arenes in high yields. Addition of organic or inorganic bases lowers the reaction temperature to 50°C.

Dichlorobis(triphenylphosphine)nickel-catalyzed cross-coupling of aryl chlorides with intramolecularly stabilized group 13 metal alkylating reagents

The intramolecularly stabilized alkyl and aryl aluminum complexes 1, 4 and 11, as well as the indium compounds 6, 9 and 10 cross-couple with a variety of chloroarenes at 80°C in the presence of NiCl 2(PPh 3) 2 to give selectively the respective alkylated arenes in high yields. Addition of organic or inorganic bases lowers the reaction temperature to 50°C.

On the reaction between alkyl or aryl aluminum chlorides and cobalt compounds

On the reaction between alkyl or aryl aluminum chlorides and cobalt compounds