Arteriovenous Hemangioma Research Articles

Eyelid Tumors at Razi and Farabi Hospitals, Tehran, Iran

Background: Eyelid tumors are common in the daily practice of skin tumors and are composed of benign and malignant lesions. Methods: This retrospective case series study collected histopathologic reports of eyelid tumors of patients treated between 2022 and 2023 in Razi and Farabi hospitals (Tehran, Iran). Patient data, including patient age, sex, location of the lesion, and recurrence, were collected. Descriptive and inferential statistics were used to characterize the subgroups. Results: The sample was composed of 154 eyelid tumor specimens, including 72 (47%) malignant cases, 80 (52%) benign cases, and 2 (1%) premalignant cases. Malignant tumors included 81.9% basal cell carcinomas (BCC), 15.3% basosquamous cell carcinomas (BSC), and 1.4% squamous cell carcinoma (SCC). The benign eyelid lesions were comprised of 20% intradermal melanocytic nevus, 11.3% epidermal cyst, 7.6% dermoid cyst, 10% seborrheic keratosis, 6.3% xanthelasma, 2.5% wart, 3.8% compound nevus, 5% fibroconnective tissue, 3.8% squamous papilloma, 3.8% neurofibroma, 2.5% comedone,2.5% apocrine hidrocystoma, 2.5% foreign body type granuloma, and 1.3% of others (arteriovenous hemangioma, cavernous hemangioma, cutaneous horn, etc.) The premalignant lesions were 2 cases of actinic keratosis. Benign lesions had an equal frequency of occurrence in the upper and lower lids. Malignant lesions were seen more in the lower lid. Premalignant lesions were seen in the lower lid. The mean age at diagnosis was 45.8 ± 23.06 years for patients with benign lesions and 63.5 ± 16.7 years for patients with malignant lesions. The mean age for patients with premalignant lesions was 81.5 ± 9.19 years (P < 0.001). Conclusions: In our study, benign lesions were seen predominantly in young persons and malignant lesions were mostly seen in elderly persons. There is an equal occurrence of malignant lesions in males and females, and recurrence after excision was infrequent.

Rheumatism as a cause of cardiac hemangioma: a rare case report and review of literature with special focus on etiology

BackgroundCardiac hemangioma is a very rare benign tumor of the heart which accounts for 1–2% of all primary cardiac tumors. Multiple cardiac hemangiomas are even rarer with only three cases published in the literature. Pathologically it can be divided into cavernous hemangioma, capillary hemangioma, arteriovenous hemangioma, mixed-type hemangioma, and so on. At present, the etiology of cardiac hemangioma is not completely clear. In this study, we present multiple cardiac hemangiomas located in the right atrium and discuss the new unreported possible cause (rheumatism) of cardiac hemangioma. This is the fourth case of multiple cardiac hemangiomas in the medical literature and the first time to present rheumatism as the cause of cardiac hemangioma.Case presentationA 53-year-old man presented to the clinic with intermittent chest tightness and shortness of breath for 2 years. On echocardiography, multiple soft tissue masses in the right atrium were found. The patient had rheumatic heart disease with severe mitral stenosis and moderate tricuspid regurgitation. Two masses with a diameter of about 20 mm and 15 mm were seen in the right atrium. One mass was located on the inferior margin of the fossa ovalis and the other was adjacent to the inferior vena cava. Both masses were successfully removed surgically. The mitral valve replacement and tricuspid valve plasty were performed at the same time. The postoperative histopathology results confirmed the diagnosis of cavernous hemangioma.ConclusionThe occurrence of multiple hemangiomas in the heart is possible, especially in the presence of rheumatism. Rheumatism is one of the possible etiologies of cardiac hemangioma. Cardiologists and cardiac surgeons should be aware of its occurrence and should consider cardiac hemangioma as a differential diagnosis especially in rheumatic heart disease patients when they present with soft tissue cardiac masses for accurate management.

A right atrial arteriovenous hemangioma excision under a beating heart after percutaneous catheter cardiac ablation

Percutaneous catheter ablation treatment is an interventional treatment method for atrial fibrillation. Herein, we report the case of a 38-year-old male patient who developed a right atrial mass after two percutaneous catheter ablations. The mass was excised by the beating heart technique, later diagnosed as arteriovenous hemangioma. Arteriovenous hemangioma had not been encountered before as a complication of catheter ablation.

P139 CARDIAC PARAGANGLIOMA: THE IMPORTANCE OF MULTIMODALITY IMAGING

Abstract Cardiac paraganglioma is a rare neuroendocrine tumour secreting norepinephrine and causing severe hypertension, palpitations, tachyarrhythmias; its precise location is very important because the compression of cardiovascular structures may result in ischaemia, arrhythmia and cardiac failure. Surgical resection represents the primary treatment modality. A 40–year–old young woman with history of hypertension, nocturnal tachycardia and sweats with elevated levels of urinary metanephrine underwent abdominal MRI angiography showing normal kidneys and adrenal glands while in the cardiac–mediastinal site a solid neoformation with contrast impregnation confirmed at subsequent chest CT scan with contrast medium and it appeared inseparable from superior vena cava and occupying the atrial chambers. Patient started therapy with an α–adrenoceptor blocker and underwent cardiac MRI documenting the intrapericardial site of the lesion infiltrating atrial septum and PET/CT scan revealing a large area of uptake of the analogue of somatostatin in the mediastinum typical for atrial paraganglioma. Subsequent angiography CT scan of the thoracic aorta and coronary CT scan showed no signs of infiltration on the great vessels and heart chambers but there was not a clear adipose cleavage plane and the mass appeared intensely vascularized by two large vessels arising from the circumflex artery and the isthmic aorta. After specialistic surgical evaluation the patient was treated with ligation of the afferent peduncle to the neoformation and biopsy of the tissue sample was performed. Post–procedure angiography CT scan showed the neoformation unchanged in size with the two unchanged afferent branches. Histological examination of the tissue sample concluded with arteriovenous hemangioma. One month after surgery elevated urinary normetanephrine levels persisted and the mass on echocardiogram was unchanged. Cardiac MRI after three months was unchanged and specialistic surgical evaluation did not suggest reoperation. Six months after surgery cardiac MRI showed mild increase in volume of the intrapericardial lesion and unchanged atrial septum infiltration. The multimodality imaging plays an important role in the diagnosis of cardiac paraganglioma. The arterial ligation, without the completely removal of the lesion, was not conclusive, the mass increased in size and the patient remained symptomatic. Surgical resection is necessary for the complete cure of the syndromes.

Arteriovenous Hemangioma of the Mitral Valve: Successful Surgical Removal in an Infant.

Arteriovenous Hemangioma of the Mitral Valve: Successful Surgical Removal in an Infant.

The arteriovenous hemangioma of the right ventricle: Case report and literature review

Introduction. Cardiac hemangiomas of the right ventricle are very rare and mostly asymptomatic benign tumors. The surgical excision is the first line treatment. Case report. We report a case of 69-year-old woman with an asymptomatic arteriovenous hemangioma of the right ventricle. The complete surgical excision was performed with the use of cardiopulmonary bypass and the patient was discharged on the postoperative day 6 after the uneventral postoperative course. There was no relapse during the six-month followup. Literature review revealed totally 35 cases of this tumors including our case Conclusion. Described procedure can be performed safely with the excellent long-term results.

Nasoangiofibroma Juvenil vs Hemangioma arteriovenoso, Reto diagnostico. Reporte de caso.

El nasoangiofibroma juvenil es un tumor vascular benigno, localmente agresivo pero poco común, representa tan solo el 0,05% de todos los tumores de cabeza y cuello, con una incidencia de aproximadamente 1:150.000. Por otra parte los hemangiomas son neoplasias benignas de las células endoteliales, representa el 7% de los tumores vasculares y son lesiones poco común de cabeza y cuello, pero ¿Son una misma entidad?, ¿Se puede trazar una línea clara para diferenciarlos?. El objetivo del presente articulo es proporcionar información acerca de estas dos entidades clínicas y responder las preguntas previamente formuladas. Este es el caso clínico de un paciente del género masculino de 19 años de edad, quien consultó por cefalea hemicraneana izquierda, otalgia y sensación de opresión ocular ipsilateral de 7 días de evolución. La tomografía axial computarizada de cráneo mostró una masa de densidad de tejidos blandos que ocupa la coana izquierda, infiltra parcialmente la región posterior de la fosa nasal izquierda, erosiona la apófisis pterigoides y el suelo de la celda esfenoidal izquierda. Se realizó biopsia por medio de nasofibrolaringoscopia en el consultorio, previa a infiltración con lidocaína, se toman dos muestras de lesión en coana izquierda sin sangrado significativo; el reporte patológico informa hemangioma arteriovenoso, por lo que se decidió realizar embolización pre quirúrgica; posteriormente es llevado a procedimiento quirúrgico sin complicaciones, finalmente la biopsia excisional reporta nasoangiofibroma juvenil con estudio de inmunohistoquimica CD31 y CD34 reactivo en pared de estructuras vasculares. El nasoangiofibroma juvenil es el tumor más común de la nasofaringe en hombres adolescente, la ausencia de epistaxis recurrente unilateral no debe descartar el diagnostico.

Patient with Huge Upper Esophageal Hemangioma

ABSTRACTBackgroundCervical esophageal hemangioma is a rare benign tumor. Symptoms may include hematemesis, dyspnea, cough, dysphagia, and chest pain.ObjectivesTo describe a case of a large esophageal hemangioma in order to raise awareness of the condition and highlight the use of a cooperative endoscopic treatment approach by a gastroenterologist and otolaryngologist with excellent results. The literature on large esophageal hemangioma is reviewed.Materials and methodsAn otherwise healthy male presented with a huge hemangioma of the upper esophagus. Imaging showed the mass hanging on a narrow stalk attached to the posterior wall of the cricopharyngeus muscle, filling the lumen of the cervical and mediastinal esophagus. Resection was accomplished with a combination of flexible gastroscopy and microscope-assisted rigid direct laryngoscopy.ResultsPathologic evaluation showed a polypoid mass covered with squamous epithelium, with multiple engorged blood vessels. Some of the vessels were wide, surrounded by a thin wall, and others were narrow with a thick wall. The histology was compatible with arteriovenous hemangioma. There was no evidence of malignancy. At the 7-month postoperative follow-up, the patient appeared well, with no dyspnea or dysphagia. Our literature search yielded only two published cases of a huge hemangioma of the upper esophagus, which were treated by open resection. Ours is the first report of the use of endoscopic excision.ConclusionLarge esophageal hemangioma should be part of the differential diagnosis of dyspnea, dysphagia, persistent cough, or chest pain. A combined approach by a gastroenterologist and otolaryngologist, working cooperatively, can facilitate the correct diagnosis and provide optimum treatment.How to cite this articleAlkan U, Geller A, Shvero J. Patient with Huge Upper Esophageal Hemangioma. Int J Otorhinolaryngol Clin 2017;9(1):25-27.

Incidental Discovery of a Large Complicated Arteriovenous Hemangioma

Incidental Discovery of a Large Complicated Arteriovenous Hemangioma

Cutaneous verruciform xanthoma

Verruciform xanthoma is an uncommon verruciform or cauliflower-like benign hyperplastic disease that occurs most frequently in the oral cavity and sometimes outside it. The lesions of verruciform xanthomacan be solitary or multiple, and grow slowly with no subjective symptoms. Histopathological manifestations are important evidence for final diagnosis, and are characterized by the presence of a large number of foam cells in the dermal papilla. The pathogenesis of verruciform xanthoma is still unclear, and is mainly associated with stimulation, trauma, inflammation, lymphedema, heredity, and so on. Verruciform xanthoma can occur alone or together with other diseases, such as discoid lupus erythematosus, lichen planus, lichen sclerosus et atrophicus, arteriovenous hemangioma, lymphedema, graft-versus-host disease, congenital hemidysplasia with ichthyosiform erythroderma and limb defects, dystrophic epidermolysis bullosa, capillary leak syndrome, etc. Key words: Skin; Xanthomatosis; Infection; Heredity; Immunity; Pathology

Angiolymphoid hyperplasia with eosinophilia associated with underlying arteriovenous hemangioma

Angiolymphoid hyperplasia with eosinophilia associated with underlying arteriovenous hemangioma

A Rare Case of Pulmonary Arteriovenous Hemangioma Presenting as a Peribronchial Mass.

Vascular tumors in the lung are unusual. The majority of previous reports described cases of multiple or solitary lymphangiomas or capillary and cavernous hemangiomas [1-4]. To date, there has been only one report describing arteriovenous malformation/hemangioma (AVMH) in the middle mediastinum [5]. Herein, we report an unusual case of pulmonary AVMH presenting as a peribronchial mass.

느린 성장력을 보이는 구치후방 협점막에 생긴 지속성 두께의 동맥혈

Caliber persistent artery (CPA) is a vascular anomaly presenting as a bluish and pulsatile artery in the subepithelial tissue. Although the incidence of CPA was debated, many CPAs occurred in the perioral and facial tissues at which the embryonal strapedial artery networks were distributed. The present study demonstrated a case of CPA occurred in the retromolar buccal mucosa in a 37 years old male. The lesion showed many pinkish granular spots, but was asymptomatic except biting irritation during mastication. It had slowly increased in size up to 20 × 25 mm for 3 years, and recently became hemorrhagic due to the biting injury between left upper and lower second molars. With the fear of oral cancer an incisional biopsy was performed, and followed by histological and immunohistochemical study. Histologically the lesion showed many tortuous artery localized at the submucosa area, and the arterial wall was thick and its lumen was narrowed and shrunken. In the immunochemistry α-SMA was positive for thick smooth muscle layer of artery and arterioles, TGase 2 was weakly positive for the luminal surface of arterial intima, and bFGF was consistently positive for the perivascular fibrous tissue. But PCNA, VEGF, CD31, CMG2, TGF-β1, HSP-70, and 14-3-3 were almost negative for the vascular tissue. Therefore, it was presumed that the lesion was not actively proliferative nor degenerative but still retained its cellular stability and slow growing potential. It was finally diagnosed as CPA differentially from arterio-venous malformation, hemangioma, lymphangioma, and squamous cell carcinoma. The retromolar buccal mucosa CPA is first reported in this study and may present usual clinical findings depending on its size and location. This asymptomatic lesion could be severely hemorrhagic by minor biting injury, therefore, precise differential diagnosis should be made through biopsy, and careful therapy be followed.

Arteriovenous hemangioma in concha of pinna causing pulsatile tinnitus: Rare case report

Arteriovenous hemangiomas are benign vascular lesions. A network of arterial and venous structures is characteristic of these cutaneous vascular tumors. Vascular lesions are commonly found in the head and neck region. These lesions may involve the ear, usually extending from external ear canal to involve the tympanic membrane. Lesions limited to the external ear canal without involvement of tympanic membrane are very few and those reported may be counted on fingers. However there is no documented cases of lesions involving and limited only to the concha of the external ear in the English literature. Here we report the first such case of arteriovenous hemangioma involving and limited to the concha of external ear.

慢性肝障害に合併した arteriovenous hemangioma の2例

慢性肝障害に合併した arteriovenous hemangioma の2例

Arteriovenous Hemangioma Formation following Radiofrequency Ablation for Inferior Turbinate Reduction

Inferior turbinate reduction by radiofrequency ablation (RFA) has been recommended as an easy and safe option for the treatment of patients with inferior turbinate hypertrophy. Complications of this type of excision are generally acceptable. We describe a case of RFA turbinate reduction that resulted in an unusual complication: the formation of an arteriovenous hemangioma.

Oral arteriovenous hemangioma in patient with hepatitis C

Oral arteriovenous hemangioma in patient with hepatitis C

Arteriovenous hemangioma in the middle mediastinum: Report of a case

Hemangiomas in the mediastinum are uncommon, and the majority of these tumors are located in the anterior mediastinum. The present report describes an extremely rare case of a hemangioma in the middle mediastinum. A 40-year-old male patient presented with a mass in the left lower lung field on radiographic screening. Chest computed tomography and magnetic resonance imaging revealed a mass measuring 2.5 cm in diameter, which was close to the descending aorta in the left middle mediastinum. The tumor resection was performed by video-assisted thoracic surgery. The thoracoscopic findings revealed a blackish brown mass with a capsule, which had not invaded the descending aorta or cardiac sac. Histologically, the tumor was composed of typical thick-walled vessels and was therefore classified as an arteriovenous hemangioma.

Arteriovenous hemangioma of the foot—A case report

We report a case of a 40-year-old woman who presented with a heel mass on her left foot. She underwent removal of the mass, which was found to be an arteriovenous hemangioma (AVH). Arteriovenous hemangioma is a rare tumours, especially in the foot which is extremely rare. This tumour should be considered in the differential diagnosis of a mass presenting in the foot.

A rare cause of hematuria in children: arteriovenous hemangioma of the bladder

Bladder hemangiomas are exceedingly rare benign tumors of the urinary bladder that account for 0.6% of bladder tumors [1]. Although this tumor can occur at any age, hemangioma in childhood is relatively rare [2]. Hemangiomas are classified as cavernous, capillary, or arteriovenous. Most hemangiomas of the bladder are of the cavernous type. In the literature arteriovenous hemangiomas have been described only in adults [3]. We report a case of arteriovenous hemangioma of the urinary bladder in a 14-year-old young boy. To our knowledge, this is the first reported case of an arteriovenous hemangioma in a child causing macroscopic hematuria.