Dear Editor, Takayasu arteritis (TA) is a rare granulomatous pan-arteritis that involves large vessels predominantly the thoracoabdominal aorta and its branches (1). Angiography, particularly subtraction angiography is the procedure of choice for diagnosis of patients with TA and provides an appropriate guide for endovascular procedure (2, 3). A ten-year-old Afghan girl was referred to the pediatric cardiology ward of Namazee Hospital, Shiraz, Iran due to a history of fever, vascular claudication, and easy fatigability in both lower extremities. In physical examination, pulseless upper extremities and carotid artery bruit were detected. One year prior to this admission, the patient was labeled as a case of Henoch-Schonlein purpura due to her first presentation with rash and fever. In spite of this management, erythrocyte sedimentation rate and C reactive protein levels had not returned to the normal range. Color Doppler sonography of both upper extremities showed the significant thickening of intima and media, diffuse lumen narrowing of both subclavian arteries, subclavian and axillary arteritis. Bringing together all the aforementioned findings, the patient’s impression was changed to the TA; therefore, prednisolone and infliximab was started. The patient was followed at the outpatient clinic. Four months later, she was admitted in the hospital due to decreased level of consciousness following left sided paralysis in both upper and lower extremities and status epilepticus. In her physical exam, motor power of the left upper and lower extremities was 1/5. The brain computerized tomography showed a small size intra-cerebral hemorrhage in the frontal lobe. Brain magnetic resonance angiography showed stenosis in the posterior, middle and anterior cerebral artery. Echocardiography showed fair left ventricular function, hypertrophic left ventricle with dyskinesia of the ventricular septum. She received plasmaphresis, rituximab, prednisolone, anticonvulsants (phenobarbital and phenytoin) and antihypertensive drugs. Multislice computerized tomography showed stenosis of both carotids and subclavian arteries (Figure 1). Figure 1. Multislice Computerize Tomography Shows Stenosis of Both Carotids And Subclavian Arteries Due to repeated convulsions and poor general condition of the patient angiography for possible stenting the stenotic cranial arteries was done. The right innominate and subclavian artery was severely stenotic and totally occluded just proximal to the origin of the vertebral artery (Figure 2). Blood flow to the right cerebral hemisphere was supplied by the collateral channel, mainly from the vertebrobasilar system. The left common carotid and subclavian arteries were also stenotic. Figure 2. A, Arch Aortogram Shows Deterioration of All the Supra-Aortic Lesions; B, Transbrachial Angiogram Reveals That the Right Subclavian Artery Was Stenotic (Arrow) Proximal to the Orifice of the Vertebral Artery. Right common carotid artery was not visualized ... Under conscious sedation anesthesia and systemic heparinization, a five-French guiding catheter was placed in the aortic arch via the femoral route and a hippocampus stent 6 × 20 mm stent was deployed at the stenotic lesion of the right subclavian artery but the stenosis could not be relieved by multiple inflation of balloon (Figure 3). Subsequently, another stent (hippocampus stent 6 × 20 mm) was placed in the stenotic part, proximal to the previous stent, which markedly improved the antegrade flow of the right common carotid artery (Figure 4). Figure 3. A and B, A Hippocampus Stent 6 × 20 mm Stent Was Deployed at the Stenotic Lesion of the Right Subclavian Artery but the Stenosis Could not Be Relieved by Multiple Inflations of Balloon; C, Another Stent (Hippocampus Stent 6 × 20 mm) Was ... Figure 4. Final Result Showed Significant Improvement of Antegrade Flow to Right Hemisphere The symptoms disappeared immediately after the first treatment, and the patient returned to her daily life activities. Neurologic examination showed no changes during one year follow up and Doppler sonography revealed both carotid stenosis and good flow through the stent. In cases of TA, stenting for these supra-aortic vessels, especially for the carotid lesions, has rarely been presented (4-6). Several authors have reported using subclavian stenting in cases of adult TA (7, 8). In our case, we think that the right vertebral artery stenting was reasonable because both carotid arteries were occluded and the right vertebral artery was functioning as the main collateral pathway to the right cerebral hemisphere, which must be preserved throughout life. To our knowledge, this is the first reported case of stenting of stenotic lesions in the supra-aortic vessels in children in Iran and also there are few reports of stenting in children in the literature.