The future of drug treatment services in today’s digital society (web society) depends, among other things, on the interoperability between health care information systems and other information systems linked to social control agencies, police forces and the judiciary. Agreements and partnerships between such different institutional actors should be strengthened, with regard to both old addictions (to psychoactive substances), and ones (regarding Internet, gambling, and so on). Possible areas of interoperability and related problems should be analyzed. We focus on four points: a) the impact models and tools of tele-e-Health in prison; b) the intertwining between e-government and new digital privacy rules with regard to addictions; c) the operational networks of inter-institutional cooperation (e.g. the recovery paths for addicted subjects reported to the judiciary); d) a federal model of tele-cooperation in prison as example of interoperability between institutions.