Health Area Research Articles

Colostrum: The Golden Elixir of Health – Unveiling Its Multifaceted Benefits in Modern Medicine

Introduction: Colostrum is uniquely rich in immunoglobulins, growth factors, antibacterial peptides, probiotics, prebiotics, and essential vitamins and minerals. Available as a supplement, BC is used to prevent gastrointestinal infections, boost immune support, and aid in managing chronic inflammation, autoimmune diseases, and even athletic recovery. Aim: The aim of this article is to assess the potential benefits of colostrum across various health areas, including gastrointestinal health, immune system support, respiratory diseases, dermatology, autoimmune conditions and the development of preterm infants. The article will also present a critical analysis of current scientific data and examine future research directions and therapeutic advancements. Review methods: This article is based on a comprehensive, non-systematic review of the scientific literature. A thorough search of the PubMed database was conducted, and 45 sources published up to 2024 were analyzed to ensure that the information presented is current and relevant. Abbreviated description of the state of knowledge: Analysis of the literature suggests that colostrum may provide passive protection, reduce inflammation and support gut integrity in preterm infants. Inflammatory bowel disease may benefit from colostrum, though results for IBS are mixed. It aids wound healing, has anti-aging effects, and shows potential in autoimmune disease management. It also boosts respiratory immunity and aids athletes' recovery and performance. Conclusions: Colostrum contains bioactive components like immunoglobulins, lactoferrin, and growth factors. While current studies highlight its benefits in enhancing immunity, supporting gut health, and managing inflammatory conditions, more comprehensive clinical trials are required to confirm its efficacy and safety across various populations and health conditions.

Screening for Frailty According to Rural and Suburban Health Areas in the Context of Adapted Integrated Care for Older People Approach: The FRAGING Study.

The integrated care for older people (ICOPE) program, developed by the World Health Organization, serves as a public health initiative to maintain older adults' functional abilities and promote healthier aging. Here, we adapted the ICOPE approach to assess overall prevalence of frailty in rural and semi-urban areas. We also investigated health-related quality of life and physical activity and sedentary behavior in older people. The FRAGING multicenter cohort study was performed on screening days dedicated to older adults (≥65 years) without chronic disease in a rural area (RU) and in a semi-urban area (SU). The study included a total of 105 participants: 98.4% of participants were frail, with a mean of 4.3 [SD:2.5] frailties per participant. RU participants had higher number of frailties (p = 0.02) and a higher percentage of frail participants in the dimensions of health-related quality of life (p<0.0001), socioeconomical level (p = 0.008), colorectal cancer screening (p = 0.022), and tetanus booster doses (p = 0.008). Globally, women were less sedentary than men (p = 0.02) and engaged more in low physical activity (LPA) than men (p = 0.01). RU participants engaged more in LPA than SU participants (p = 0.03). The prevalence of frailty is alarmingly underestimated in older adults without chronic disease. This study demonstrated the need to propose appropriate, validated screening tests that consider territorial issues and organization of care delivery. The ICOPE framework serves as a good startpoint for reorganizing person-centered healthcare pathways.

Harnessing genomic technologies for one health solutions in the tropics.

The targeted application of cutting-edge high-throughput molecular data technologies provides an enormous opportunity to address key health, economic and environmental issues in the tropics within the One Health framework. The Earth's tropical regions are projected to contain > 50% of the world's population by 2050 coupled with 80% of its biodiversity however these regions are relatively less developed economically, with agricultural productivity substantially lower than temperate zones, a large percentage of its population having limited health care options and much of its biodiversity understudied and undescribed. The generation of high-throughput molecular data and bespoke bioinformatics capability to address these unique challenges offers an enormous opportunity for people living in the tropics. MAIN: In this review we discuss in depth solutions to challenges to populations living in tropical zones across three critical One Health areas: human health, biodiversity and food production. This review will examine how some of the challenges in the tropics can be addressed through the targeted application of advanced omics and bioinformatics and will discuss how local populations can embrace these technologies through strategic outreach and education ensuring the benefits of the One Health approach is fully realised through local engagement. Within the context of the One Health framework, we will demonstrate how genomic technologies can be utilised to improve the overall quality of life for half the world's population.

IMPACT OF SOCIAL POLICY ON CPI IN MALAYSIA BETWEEN 2005-2023

The social policy that the government in Malaysia implemented had positive influences on the local community and economy in Malaysia as well, which focused on the Consumer Price Index (CPI) and the idea that the trend would change if social policy were made. A study focused on the effect of social policy specified in Malaysia’s education, health, and housing areas on CPI. This study used the quantitative method based on the model of ordinary least squares (OLS), and CPI (Y) was the dependent variable, while government education spending (X1), government health spending (X2), and government housing spending (X3) were the independent variables. According to the results of this research, it seems that there was a positive impact of social policy on the CPI, but no significant social policy that the Malaysian government implemented had a determined power over the CPI. Most country research on the impact of social policy on CPI was also insignificant, based on the previous studies. These findings found that CPI was affected by other factors apart from social policy as well and need to be studied as potential factors in the future, as there was a slight significance. To emphasize this study, ARMA is the best-suggested way to analyse the trend of CPI in Malaysia.

Evaluation of New Mental Health Diagnoses After Pediatric Traumatic Injuries at a Level 1 Pediatric Trauma Center.

Traumatic injury is associated with significant mental health morbidity. To evaluate the need for implementation of active-post injury mental health screening at a Level 1 Pediatric Trauma center, we aimed to characterize all new mental health diagnoses after injury and evaluated for patient or injury factors that may aid in targeting of future screening. A single-center retrospective analysis of trauma patients aged 6-18years presenting in 2022 was performed. Our primary outcome was a new DSM-5 mental health diagnosis documented after traumatic injury. Patients with and without a new mental health diagnosis were compared by age, sex, race, ethnicity, injury type/mechanism, injury severity score (ISS), intensive care unit (ICU) admission, and length of stay (LOS). 492 patients were included. Their median (IQR) age was 13.5 (10.4, 15.4) years. The median (IQR) follow-up interval was 157 (9, 429) days. There were 24 (4.9%) children with a new mental health diagnosis: 12 (50%) with trauma-related stress disorders, with the remaining having diagnoses such as depressive or anxiety disorders. Patients with a new mental health diagnosis had longer LOS (3.0 [1.8, 7.5] vs 2.0 [1.0, 3.3] days, P = 0.02) and were more likely to have sustained penetrating injury (P = 0.01). There were no differences in demographics, rates of preexisting mental health diagnosis or area deprivation index (P > 0.05). There were fewer new mental health diagnoses in our cohort than expected, likely underestimating the acute need. Comprehensive post-injury screening is imperative to sufficiently identify and intervene upon mental health morbidity after pediatric trauma.

Israel as India’s Pivot in the IMEC

India’s policy on the Middle East has broadly been bilateral and in the process, it had to strike a fine balance in furthering relations with countries that are rivals. Its “Look West” policy, introduced in 2005, made some inroads in the Middle East, enlarging its economic and strategic footprints. In recent years, it has stepped up its engagements through minilateral and multilateral frameworks by joining India, Israel, the United States, and the United Arab Emirates (UAE) (I2U2) grouping and jointly launching the India-Middle East-Europe Economic Corridor (IMEC). The I2U2 was launched in 2020 for expansive economic cooperation in vital areas of water, energy, transportation, space, health, and food security. It was catalyzed in the backdrop of the Abraham Accords. In September 2023, during the G20 summit in New Delhi, seven countries, namely, India, Saudi Arabia, the UAE, France, Germany, Italy, the United States, and the European Union (EU), signed a Memorandum of Understanding for the IMEC. The October 7, 2023 attack on Israel and its attendant consequences have threatened to derail this multilateral cooperation, but India and other signatories have remained steadfast in their commitment to IMEC, raising hope for its future.

EVALUATION OF ANXIETY AND DEPRESSION AMONG NURSING STUDENTS OVER THE COURSE OF A YEAR

Introduction: Anxiety and depression observed in young people are associated with poor quality of life during college, not only in terms of poor eating and lifestyle habits, but also the inability to deal with problems associated with college and their future profession. Each stage of life, with its due concerns and questions, interferes in the level of overload and pressure among college students. Objective: This study aimed to investigate the levels of anxiety and depression among nursing students at a public university in the interior of Paraná, at three different times, over the course of one year. Method: This is a quantitative, descriptive, exploratory study with a longitudinal design. Data collection took place at three different times throughout the year (March, July and November) of 2019, using the Hospital Anxiety and Depression Scale (HADS), validated for Brazil to assess anxiety and depression, as well as an instrument for sociodemographic and academic characterization of the subjects, constructed and validated (face, content and semantics) for this study, by experts in the area of ​​education and mental health. Descriptive and inferential analyses were performed for the variables of interest, as well as the calculation of Cronbach's alpha to assess the internal consistency of the items of the HADS scale. Student's t-test, Analysis of Variance (ANOVA) and one-way ANOVA with repeated measures were used to compare the measures of anxiety and depression, as well as with sociodemographic and academic variables among the students, throughout the three evaluations. Results: Among the 77 participating students, 92.2% were women with a mean age of 21 years; 15.4% were married; 74.6% declared themselves to be Catholic; 65.8% declared themselves to be good students. Age and the fact of having a subject dependency were considered statistically significant when compared between the years of the course. Anxiety averages in the three measures, respectively, for general nursing: 10.0; 9.9; and 9.5, not being considered statistically significant. And for depression: 7.1; 7.4; 7.1 being statistically significant for the third evaluation. There was no statistically significant variation between the evaluation of anxiety and depression levels in the three measures. Conclusion: The levels of anxiety and depression evaluated by HADS, in the General Nursing group were not so expressive quantitatively, but are still higher than other studies involving nursing and/or health area university students. Data from the study indicated no difference in anxiety and depression levels, at different times, throughout the year. Not having reached the population of academics of the course in question, as a whole, in the evaluations carried out, was one of the limitations of the study.New studies are being carried out to try to explain the variations in anxiety and depression levels among students on the Nursing course in question, with methodological approaches that allow the subject studied to have a voice.

Challenges of the Biopharmaceutical Industry in the Application of Prescriptive Maintenance in the Industry 4.0 Context: A Comprehensive Literature Review

The biopharmaceutical industry has specificities related to the optimization of its processes, the effectiveness of the maintenance of the productive park in the face of regulatory requirements. and current concepts of modern industry. Current research on the subject points to investments in the health area using the current tools and concepts of Industry 4.0 (I4.0) with the objective of a more assertive production, reduction of maintenance costs, reduction of operating risks, and minimization of equipment idle time. In this context, this study aims to characterize the current knowledge about the challenges of the biopharmaceutical industry in the application of prescriptive maintenance, which derives from predictive maintenance, in the context of I4.0. To achieve this, a systematic review of the literature was carried out in the scientific knowledge bases IEEE Xplore, Scopus, Web of Science, Science Direct, and Google Scholar, considering works such as Reviews, Article Research, and Conference Abstracts published between 2018 and 2023. The results obtained revealed that prescriptive maintenance offers opportunities for improvement in the production process, such as cost reduction and greater proximity to all actors in the areas of production, maintenance, quality, and management. The limitations presented in the literature include a reduced number of models, the lack of a clearer understanding of its construction, lack of applications directly linked to the biopharmaceutical industry, and lack of measurement of costs and implementation time of these models. There are significant advances in this area including the implementation of more elaborate algorithms used in artificial intelligence neural networks, the advancement of the use of decision support systems as well as the collection of data in a more structured and intelligent way. It is concluded that for the adoption of prescriptive maintenance in the pharmaceutical industry, issues such as the definition of data entry and analysis methods, interoperability between “shop floor” and corporate systems, as well as the integration of technologies existing in the world, must be considered for I4.0.

Constantly changing, constantly adapting: Lives and life-course data of children and childhood social care

ObjectivesChildhood social care can lead to lifelong problems affecting health, educational attainment and other areas of a person’s life. Improving outcomes for children are therefore key policy objectives in many nations. The aim of this workshop was to inspire and drive forward life-course research on childhood social care internationally. ApproachThe workshop included presentations on the themes of the data jigsaw across the family life-course and data sovereignty and engagement. Presentations under each theme were followed by group activities and discussions. ResultsAdministrative data collections that include longitudinal details on childhood social care, developmental, health and other outcomes are becoming increasingly available for researcher purposes. Examples include the BEBOLD platform and the New South Wales Child E-Cohort in Australia, ECHILD in England and the Welsh SAIL Databank. First nations data sovereignty and engagement of childhood social care recipients has become a norm in many nations and led to improvements in research, including in methodology and interpretation of results. Together, improved access to data and meaningful stakeholder engagement can inform policy and practice to improve outcomes for children and young people. ConclusionsBarriers exist to understanding the family and home environments, such as very limited or no information about the fathers and other household members. Capturing populations who move between jurisdictions, e.g. migrants, is limited as administrative data is difficult to share across devolved nations/federated states. In some cases, a mismatch exists between expectations of meaningful engagement and institutional/research culture, resource and skill availability.

Knowledge, attitude and practice regarding sexual and reproductive health rights among married adolescents in urban slums of Bangladesh: A cross-sectional survey

Background: Adolescents, especially married adolescents living within urban slum communities, encounter significant difficulties in obtaining and exercising their sexual and reproductive health rights (SRHR). This study aimed to determine the knowledge, attitude, and practice of SRHR and its associated factors among married adolescents living in urban slums. Methods: A cross-sectional survey of 500 married adolescent girls living in slums in Dhaka and Gazipur, Bangladesh, was conducted in the icddr,b Health and Demography Surveillance System areas. We interviewed them using a pretested questionnaire to assess their knowledge, attitude, and practice of SRHR. Data on their sociodemographic variables, such as household asset items and age and education, were collected. Principal component analysis was used to create wealth indices. Results: Knowledge of self-care during menstruation and the oral contraceptive pill was almost universal, though knowledge of condoms, abortion, danger signs of pregnancy and sexually transmitted infections was low. They (70%) agreed that young people should have access to menstruation-related hygiene facilities, contraception and sex education, though there was less agreement regarding abortion being a woman’s right. The use of antenatal care and institutional-level delivery was also low. Age, years of schooling and prior pregnancy were positively associated with their knowledge levels. Important attitudinal and practice variations were noted between regions, Gazipur being the most disadvantaged. Conclusion: There are important gaps in knowledge and practice in SRH service-seeking in this slum population. Heterogeneity in the slum population must be recognised to design services that reach the most disadvantaged group.

The Relationship Between Serum Cholesterol, Triglycerides, and Self-Reported Appetitive and Reactive Aggression, as Well as Violent Crimes in Male Forensic Patients with Substance Use Disorder

Numerous studies have linked lower levels of serum cholesterol with heightened aggression, violent crimes, and violent deaths across diverse populations, including forensic psychiatric patients, criminals, and the broad public. Interestingly, this association appears to be more pronounced in men than in women. Conversely, findings regarding serum triglycerides present a more nuanced picture, with some studies indicating heightened aggression with elevated levels and others suggesting the opposite. However, most studies have neglected to examine this phenomenon in conjunction with psychological traits. Additionally, no prior research has explored the association between serum lipid levels and different types of aggression, e.g., reactive, instrumental, or appetitive. Considering these gaps, our study aimed to assess serum cholesterol and triglyceride levels upon clinic admission and correlate them with scores from the Appetitive and Facilitative Aggression Scale (AFAS), a self-rating questionnaire assessing reactive and appetitive aggression. We conducted our investigation on a cohort of 135 forensic psychiatric patients undergoing drug addiction treatment under Section 64 of the German Criminal Code. This provision offers a nearly unique opportunity worldwide for individuals who have committed crimes under the influence of drugs or in the context of their addiction to receive specialized treatment. Using non-linear Spearman correlation analyses, we observed an inverse relationship between serum concentrations of both cholesterol and triglycerides and AFAS appetitive violence scores but not for reactive aggression. Additionally, triglyceride levels exhibited an inverse association with the prevalence of violent crimes as an index crime. In conclusion, blood lipids may affect numerous areas of health and disease beyond what is currently known, offering a potential shift in how we understand their role in aggression.

Development of Qualified Items for Nursing Education Assessment: The Progress Testing Experience

Aimto analyze the psychometric characteristics of items in the nursing inter-institutional progress testing for the years 2019, 2021, 2022 and 2023. BackgroundProgress testing is a validated method for evaluating professional undergraduate education, aimed at identifying knowledge gain in a continuous and progressive manner, with potential benefits for nursing education. However, for its results to be useful, the evaluation items used in the test must have good psychometric performance. Designa cross-sectional study. Methodsa sample of 377 items (multiple-choice questions) was applied to 4,678 students in four years of progress testing. The difficulty and discrimination indexes were analyzed using descriptive statistics, ANOVA and simple linear regression. ResultsThe average difficulty index of the test items ranged between 0.39 and 0.46. The areas of child and adolescent health, women's health and adult health had the most difficult items, while the areas of management, mental health and public health had the least difficult items. Discrimination index ranged from 0.35 to 0.43. There was a difference between discrimination index between the years of application (p<0.001), with a significant increase in the discrimination index (p<0.001) in the trend analysis. Students in the final years showed lower levels of difficulty and discrimination when compared with students in the initial years, demonstrating that the test is easier and there is less dispersion of performance among students in the final years. ConclusionsThe items are not difficult and have good discrimination. A gradual annual increase in the discrimination index of the items was observed. This study provides useful information for the psychometric analysis and quality assurance of knowledge assessment items, both for the implementation of similar PT experiences and in the use of multiple-choice questions for other knowledge assessment purposes.

Interventions involving nudge theory for COVID-19 vaccination: A systematic review and meta-analysis.

New approaches to mitigate vaccine hesitancy and improve vaccine uptake are urgently needed. Nudging has shown effective results in several health areas. However, the effectiveness of interventions involving nudge theory in increasing COVID-19 vaccination remains unclear. We searched PubMed, Web of Science, and Scopus for randomized controlled trials published before December 31, 2022, to determine whether interventions involving nudge theory improved COVID-19 vaccination behavior and intent. Risk ratio (RR) and a 95% confidence interval (CI) were used as pooled measures to assess vaccination behavior. Intention to vaccinate was reported in a narrative synthesis. Sixteen randomized controlled trials involving 176,125 participants were included. Interventions involving nudge theory weakly boosted the COVID-19 vaccine uptake rate (RR = 1.21, 95% CI [1.07, 1.36], p < .01). Subgroup analysis showed a weak positive effect of social norms (RR = 2.04, 95% CI [1.61, 2.57]), defaults (RR = 1.32, 95% CI [1.03, 1.69]), and salient reminders (RR = 1.19, 95% CI [1.04, 1.36]). Nudge interventions integrating multiple components were more efficacious in increasing vaccination rates compared to nudge alone. The effect of nudging interventions weakened over time (p < .001). Most studies (10 of 11) involving vaccination intention outcomes showed positive or partially positive results. Interventions involving nudge theory can promote COVID-19 vaccination behavior and intentions. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Musculoskeletal Clinical Online Cases With a Focus on Anatomy for Preclinical Learners.

While musculoskeletal disorders are leading causes of medical visits, musculoskeletal education is underrepresented in US medical curricula. Previous studies have demonstrated that undergraduate medical students often fail to demonstrate competency surrounding musculoskeletal disorders. More educational content is needed to support musculoskeletal knowledge in learners. We developed an online, case-based musculoskeletal module for second-year medical students alongside their standard course material and presented clinical cases with multiple-choice question quizzes regarding the presentation, diagnosis, and anatomic correlation of musculoskeletal conditions. Cases, under 10 minutes each, targeted common, medically important areas of musculoskeletal health. Grades in the required musculoskeletal course were significantly and positively correlated with online module quiz performance. 258 (73%) of 354 students completed at least one quiz, and students completed an average of 14 out of 15 quizzes. Learners who completed more than 50% of the quizzes performed significantly better in the course than those who completed fewer quizzes; this was true for a formative internal course exam (p = .035), an NBME customized assessment (p = .008), and the course overall (p = .021). Additional analyses of students' perceptions revealed that students valued the self-directed online learning environment. The high completion rate (73%) for the online module also signaled student value in the content and format. This module represents educational material that has been demonstrated to improve medical student musculoskeletal learning. Additionally, the module could be expanded to address inadequacies in orthopedic education among other students, such as allied health learners.

Dünn in der Fläche? Regionale Disparitäten in der Hospiz- und Palliativversorgung in Deutschland

IntroductionOutpatient and inpatient hospice and palliative care services have been significantly expanded in Germany in recent decades and are increasingly being supplemented by day care services. However, the availability of these services varies greatly from region to region. The extent to which the availability of these care structures is matched by a regional need based on local population structures is as yet unknown. MethodsIn four Poisson regression models, the relationship between population indicators from the areas of demographics, employment, income, education and health and the number of offers of outpatient and inpatient hospice work and palliative care is exploratively examined. The cumulated data at district level is drawn from the INKAR database of the Federal Institute for Research on Building, Urban Affairs and Spatial Development on living conditions in Germany and from the guide of the German Association for Palliative Medicine. By means of logistic regression, factors influencing the establishment of day care services will also be identified. ResultsThe analysis included 401 districts and cities in Germany. The number of inhabitants, settlement density, and the average age of inhabitants are the strongest predictors of the number of palliative care services. In metropolitan regions, both outpatient palliative care services and palliative care units tend to be more frequently available, while the number of outpatient hospice services and inpatient hospices increases in districts with a higher number of inhabitants regardless of settlement density. The regression model was unable to demonstrate a significant influence on the emergence of semi-inpatient care facilities, neither for the population indicators nor for the existing care structures. DiscussionRegional population structures can only partially explain the geographically uneven distribution of hospice and palliative care services in districts and cities in Germany. Despite an increase in hospice and palliative care services, fewer hospice and palliative care structures are available in low population density regions that tend to have a higher share of older inhabitants. ConclusionFuture health care planning should give more consideration to other population characteristics than to population size alone in order to improve care in regions with higher care needs that are, for example, due to a higher proportion of older residents. Subsequent studies should investigate which population characteristics can best describe the actual care needs.

Prevalence and relevance of H558R in the efficacy and toxicity of flecainide in patients with atrial fibrillation: a cohort study.

The SCN5A gene polymorphism histidine-558-to-arginine (H558R) has been associated with atrial fibrillation (AF) and may affect the therapeutic effects of flecainide. This study aimed to assess the prevalence of the H558R polymorphism in a European cohort of patients with AF and examine its association with flecainide's effects on AF recurrence and toxicity. This cohort study included patients diagnosed with AF and prescribed flecainide between 2017 and 2021 in a regional health area. Patients without the polymorphism (H558R-/-) were compared with heterozygous patients (H558R+/-) for a primary outcome of combined 6-month AF recurrence or toxicity. Secondary analyses evaluated the long-term outcomes and compared the prevalence of H558R in the AF cohort to a general population sample (n=3401). A total of 104 patients were enrolled, with 57% H558R-/-, 37% H558R+/- and 6% H558R+/+. The prevalence of the H558R polymorphism was significantly higher in the AF cohort than in the general population (43.27% vs 24.37%, prevalence ratio 1.78, 95% CI 1.41 to 2.23, p<0.01). H558R+/- patients had a significantly lower risk of 6-month AF recurrence or toxicity (p=0.023, risk ratio 0.423, 95% CI 0.189 to 0.947), corresponding to an absolute risk difference of 21.5%. These findings were similar in the multivariable analysis. In long-term follow-up, H558R+/- patients continued to demonstrate a lower risk of AF recurrence or toxicity (p=0.039, HR 0.53, 95% CI 0.276 to 0.999). The H558R polymorphism is more prevalent in patients with AF compared with the general population and its presence is associated with a more favourable response to flecainide treatment.

Influence of the Olfatín Project on the reduction of pain related to intranasal influenza vaccination, as part of a school influenza vaccination program

PurposeTo evaluate the influence of viewing the Olfatín Project video on the assessment of school LAIV-associated pain in three and four-year-old children through the Wong Baker Faces® pain classification scale. Design and methodsA three-arm randomized multicenter clinical trial with a placebo control group was carried out. The main variable measured was pain, assessed through the score on the Wong Baker Faces® Pain Rating Scale. There were a total population of 4591 children three and four-year-olds (born in 2019 and 2020) and who attended the 1st and 2nd year of early childhood education. Before the school vaccination, researchers randomly assigned participant schools corresponding to each of the basic health areas to each of the three study groups: Olfatín's video viewing, a control video viewing not related to influenza and no video viewing. ResultsNo significant differences according to sex, age or the minor's grade according to the assigned intervention were detected. 72.3% of those vaccinated assigned a 0 from the Wong Baker Faces® scale: 75.4% of those who watched Olfatín's video, 68.3% for those in Drilo's group and 72.8% for those who didn't watch any video, but without significant differences (p = 0.08). There were no significant differences either stratifying by sex. ConclusionLAIV is a painless vaccine for children, which has to be taken into account by the health authorities when planning the pediatric influenza vaccination campaign. Practice implicationsOlfatín's cartoon video can be used by professionals to create a greater experience for children and therefore a better acceptance.

OVERVIEW OF CAREER MANAGEMENT IN DENTISTRY: CHALLENGES AND TRENDS FOR THE FUTURE FROM THE STUDENTS' PERSPECTIVE

Career management has faced several innovations, due to the economy, politics and social contexts. Such changes are justified by technological advances, globalization, communication processes, outsourcing, and unemployment (PEREZ, 2021). It is relevant to reflect and outline a career plan, in order to find a way to put it into practice, to have the attitude of moving towards the achievement of both personal and professional goals. To describe the perception of career management, as seen by students in the health area at a private university in Belo Horizonte. This is a quantitative research, with the purpose of obtaining results that answer the guiding problem of this study. All dentistry students from Brazilian public and private universities were included, who answered a semi-structured questionnaire, reaching the following results: Gender 76.9% of the interviewees are female and 23.1% male; Age 58% of the students are in the 25-year age group; working in the area represent 38%; 79.3% of these students are studying their first undergraduate degree; 20.7% are in their second degree. Regarding the income profile, 37.9% receive between 1 and 2 thousand reais per month, and 50.7% have a salaried employment relationship, and 70.9% have never taken a vocational test to choose dentistry. Therefore, it is possible to conclude that in the current times, important changes in the work scenario are visible. Having achieved the objectives of this study, evidencing the commitment of dentistry students, however, contrary to expectations, it was noted that the individual initiative to develop the career is unsatisfactory, as well as there is no promotion by the HEIs due to the lack of disciplines on clinical career management and offices during the course.

Perspectives of Regenerative Medicine in Dermatology and Cosmetology

Regenerative medicine has revolutionized the field of biological sciences, pharmacology and healthcare, bringing a new approach to treatments of various health conditions. Dermatology and aesthetic medicine are interested in these new scientific approaches as well. From this point of view, many areas of skin health and cosmetology may be involved, but several questions should be answered before these procedures become routine in offices and hospitals. Indeed scientific, ethical, and financial issues still have to be addressed in detail. Nevertheless, ongoing research and technological advancements are expected to further improve therapies. The integration of artificial intelligence and machine learning could enhance the precision of regenerative treatments, making them more effective and accessible in forthcoming years.

Multi-Scenario Simulating the Effects of Land Use Change on Ecosystem Health for Rural Ecological Management in the Zheng–Bian–Luo Rural Area, Central China

A healthy rural ecosystem ensures a win–win situation for both economic growth and ecological conservation. However, the impact of land use changes at the rural level on ecosystem health remains unclear. This study focuses on the rural scale of Zheng–Bian–Luo, analyzing changes in land use from 2000 to 2020. Using the “Ecosystem Vigor-Organization-Resilience-Services” model, the study evaluates the spatiotemporal patterns of ecosystem health. The Patch-generating Land Use Simulation (PLUS) model was employed to simulate land use and ecosystem health in 2035 under three scenarios: Natural Development (ND), Ecological Protection (EP), and Cropland Protection (CP). The findings are as follows: (1) From 2000 to 2020, the area of cultivated land in Zheng–Bian–Luo rural areas decreased, and the area of forest land first decreased and then increased. (2) During the study period, ecosystem health improved as ecosystem vigor, organization, and services increased. Low-value areas of ecosystem health showed a shrinking trend, most notably in Kaifeng. (3) By 2035, under the EP scenario, forest land increased by 76.794 km2, while it decreased under the CP and ND scenarios. Construction land showed an increasing trend in all three scenarios, with the ND scenario seeing the largest increase of 718.007 km2. (4) In 2035, ecosystem health is projected to decline under the ND scenario due to reduced forest land and increased construction land. The CP scenario showed no significant change in ecosystem health, but the southwestern rural areas of Luoyang improved. The EP scenario saw an overall increase in ecosystem health, highlighting land use optimization as beneficial. Local governments are encouraged to create ecological protection plans balancing ecological and cultivated land protection, focusing on sensitive areas such as the Songshan region and southwestern mountainous areas of Luoyang for coordinated development.