As one of the main areas of Dentistry, Endodontics aims to repair periradicular tissues, allowing the affected tooth to reestablish its functions through its treatment. With this objective in mind, different types of root canal sealers (RCS) have been created in order to improve the healing of desired tissues. The main objective of this work is to analyze, through a literature review, studies on the use of second generation bioceramic cement in the voids of root canal systems, highlighting the essential properties in its clinical use, its advantages and disadvantages, and also compare its effectiveness with the oldest cements on the market. The methodology used was bibliographic research, exploring in sources such as research articles, meta-analysis and clinical trials published in Portuguese and English, selected through the search descriptors PubMed, Lilacs and Scielo. The results of the studies showed the efficacy in the use of bioceramic cement in the voids of root canal systems, since they have the ability to fill and seal, manifesting dimensional stability, avoiding the recontamination of the canals, among other benefits. However, in relation to retreatment, this type of sealer presented some difficulties in its removal when traditional techniques were used, being indicated to associate the use of mechanized techniques to improve its removal. It could also be observed the need for further studies in this area, as the analyzed studies have limitations, due to such types of cements being still relatively new to the market, meaning that the long-term success rate of the treatment is still unclear.
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