Ardabil City Hospital Research Articles

Correlation between the elevated level of interleukin-6 following actemra administration and the mortality rate of seven severe COVID-19 patients

The escalation and involvement of Interleukin 6 (IL-6) in the pathogenesis of COVID-19 have been documented in numerous studies and are recognized as a diagnostic criterion, disease biomarker, and therapeutic objective. Our study aims to explore the correlation between the elevated level of IL-6 following actemra administration and the mortality rate of seven severe COVID-19 patients who were admitted to the special care department of Ardabil city hospital. In this case-series study, 7 patients with severe COVID-19 were admitted to the special care department of Ardabil city hospital were included in the study. Venous blood samples (3 cc) were taken in admission and after actemra injection. The demographic characteristics of the patients, including age, sex, duration of hospitalization, need for intubation, BMI, and interleukin 6 levels, were recorded in a checklist. The patients were then monitored for their clinical course, disease outcome, and complications. The mean IL-6 before and after actemra was 413.57±138.38 and 805.50±128.18, respectively and the difference was significant. After treatment by actemra, 71.4% of patients were discharged from hospital without mortality. Although elevated IL-6 levels have been associated with cytokine storms and unfavorable consequences in COVID-19 patients. This report indicates that high interleukin levels do not guarantee mortality. Young individuals without underlying conditions were ultimately discharged from the ICU despite severe inflammation, thanks to timely treatment and albeit with severe disability.

Study the frequency of substance abuse in patients with perforated peptic ulcer disease

Background: Peptic ulcer perforation is one of the severe complications of peptic ulcer disease (PUD). Patients with perforated peptic ulcers usually are presented by the acute abdomen. In some studies, substance abuse is one of the peptic ulcer risk factors. Our study aimed to evaluate the frequency of substance abuse in patients with perforated peptic ulcers referred to Ardabil city hospital from January 2020 until March 2021. Methods: This descriptive cross-sectional study was done on 60 patients with peptic ulcer perforation in Ardabil city hospital from January 2020 until March 2021. Data collected by a checklist and analyzed by statistical methods in SPSS version 25. Results: Of all patients, 13 patients (19.7%) had substance abuse and all of them were male. Of all 13 patients with substance abuse, 9 (69.2%) had opium use. Conclusions: The results showed that substance abuse among patients with peptic ulcer perforation, can be consider as a possible risk factor for peptic ulcer perforation, but more studies should perform to identify the effective factors and variables that can be main role in peptic ulcer perforation in patients.

Frequency of lumbar magnetic resonance imaging findings in patients with low back pain

<p class="abstract"><strong>Background:</strong> Back pain is one of the main causes of disability and has been the most common cause of disability in the last decade. MRI imaging is able to identify soft tissues, including the intervertebral disc, nerves, and muscles, that are potential sources of back pain; it should be noted, however, that in some cases MRI is not able to identify the source of low back pain.</p><p class="abstract"><strong>Methods: </strong>This cross-sectional study was done on 256 patients who referred to the imaging ward of Ardabil city hospital for lumbar MRI from September 2020 and September 2021. These patients in terms of gender, age, type of insurance, disc dehydration, disc protrusion, disc extrusion, disc sequestration, disc dehydration, spondylolisthesis, retrolysis, presence of Taylor cyst, hemangioma, vertebral fracture, spinal abnormality, spinal abnormality Bone marrow SG, spinal canal stenosis, furaminal stenosis, modic changes and the presence of scoliosis were evaluated.</p><p class="abstract"><strong>Results:</strong> The mean age of patients was 45.10 with a standard deviation of 14.28 years. 152 patients (59.4%) were male. 240 patients (93.7%) had health insurance.55 patients (21.5%) had normal MRI. The most common MRI findings in the present study were: extrusion (67.6%), intervertebral disc dehydration (59.4%), protrusion (40.2%), spinal canal stenosis (29.7%) furaminal stenosis (24.2%), retrolysis (19.5%), lumbar scoliosis (14.7%), modic changes in the lumbar vertebrae (14.5%), scoliosis (13.7%), hemangioma (10.5%), spondylolisthesis (9.4%), sequestration (3.1%), spinal abnormalities (2%) and bone marrow SG (1.6%).</p><p class="abstract"><strong>Conclusions: </strong>Based on the results, the most common abnormal findings in MRI of patients with low back pain were: extrusion, protrusion and dehydration of the intervertebral disc. Also, most of these changes were in the lower levels of the lumbar vertebrae.</p>

Comparing the Efficacy and Side Effects of Intravenous Ibuprofen and Acetaminophen in Pain Control Following Laparoscopic Cholecystectomy

BACKGROUNDThe importance of using effective postoperative analgesia is widely accepted. Systemic opioids are the gold standard for reducing severe pain after surgery, but the side effects have limited the use of adequate doses. We aimed to evaluate the effect of adding intravenous acetaminophen and intravenous ibuprofen to fentanyl on patient-controlled analgesia. METHODSIn this randomized clinical trial study in Ardabil city hospital at 2019, 90 patients undergoing elective laparoscopic cholecystectomy were randomly divided into three groups. The control group (n=30) received normal saline, the acetaminophen group (n=30) received 1g intravenous acetaminophen, and the ibuprofen group (n=30) received 800 mg intravenous ibuprofen. All patients received a pain control by intravenous pump containing fentanyl (15µ/ml). The drugs were injected intravenously after surgery. Shoulder and abdominal pain scores, sedation rate, nausea and vomiting, satisfaction, and the doses of fentanyl and meperidine were recorded in SPSS software within 24 h after surgery. RESULTSThe mean abdominal pain scores in ibuprofen (3.02) and acetaminophen (2.89) groups were not significantly different (P=0.719) but were significantly lower than in the control group (5.10) (P<0.001). The severity of shoulder pain, nausea and vomiting, sedation, and fentanyl intake were not significantly different in the ibuprofen and acetaminophen groups but were significantly lower than in the control group.CONCLUSIONThe use of both intravenous acetaminophen and ibuprofen in pain control after surgery can reduce the need for opioid use. Acetaminophen can also be a suitable alternative for postoperative pain control in patients that are unable to use NSAIDs.

Comparison of the effect of kalsitrapine and metformin as adjunctive therapy in the treatment of infertility in women with polycystic ovary syndrome

Background: Chronic anovulation is one of the most common causes of infertility. In women with polycystic ovary syndrome (PCOS), other factors related to oocyte quality or endometrial and nesting disorders may also play a role. Infertile and non-ovulatory women who tend to become pregnant are candidates for ovulation induction. The aim of this study was to evaluate the effect of Kalsitrapine and metformin on the treatment of patients with PCOS.Methods: The clinical trial study was performed on 80 female patients with PCOS who had referred to Ardabil city hospital for infertility treatment were randomly divided in two groups with personal consent. One group received Kalsitrapine and another group received metformin.Results: The mean age of all patients was 26.08±5.21. There was no significant difference between 2 groups in term of age and BMI. There was no statistically significant difference between the two groups in terms of primary and secondary infertility. The mean duration of infertility was 3.68±3.49 years. There was no statistically significant difference between the 2 groups in terms of infertility duration. There was no statistically significant difference between the 2 groups in terms of the type of menstrual cycle. The response rate to treatment was 17.5% in the metformin group and 10% in the Kalsitrapine group. There was no statistically significant difference between the 2 groups in terms of response to treatment. In comparison, none of the studied factors in the 2 groups was significantly associated with the response to treatment.Conclusions: It is true that the recovery rate of the herbal medicine Kalcitropine in this study was slightly lower than metformin, but due to the side effects of metformin, including lethargy, abdominal pain, diarrhea, headache, constipation, bloating, weight loss, heartburn, nausea and Vomiting, unpleasant taste of metal in the mouth In some people, such people may be prescribed kalcitrapine for a longer period of time to evaluate its effect.

Prevalence of infectious abortion and its complications in pregnant women hospitalized in Ardabil city hospital during 2011-2018

Background: Infectious abortion and its mortality is one of the most serious health threats to women. Infectious abortion with high prevalence rate is more accessible in many of developing countries. The aim of current study, was to investigate the prevalence of infectious abortion and its complications in pregnant women hospitalized in Ardabil city hospital during 2011-8.Methods: In this retrospective cross-sectional study which done on pregnant women with symptom of infectious abortion who admitted to Alavi hospital in Ardabil city during the years 2011-2018. Data collected by a checklist including demographic and clinical information and then analyzed by statistical methods in SPSS version 20. Results: The rate of infectious abortion in this study was 40 people per 50,000 live births. The mean age of the studied women was 32.58±5.35 years. The highest number of infectious abortion was related to the women in the gestational age group over 13 weeks (50%). Most of women with 80% had fever and 52.5% of women had an open cervix at the time of referral. Complications of infectious abortion included peritonitis, uterine rupture, septic shock, and DIC.Conclusions: Results showed that the rate of infectious abortion in this study was 22.5% that generally due to manipulation by methods such as curettage, drug use and its side-effects. By considering the average age of women about 32 years and problems related about pregnancy, so programing and training in this themes could prevent many of these problems in pregnant women in future.

The Epidemiological, Risk Factors and Clinical Characteristics of Ischemic Stroke in Ardabil Province, Iran: a Hospital Based Study

Introduction: Stroke is the third most common cause of death in world after heart diseases and cancer. Due to the higher rate of stroke and less attention to its occurrence, assessing the prevalence of ischemic brain stroke and its clinical patterns across countries and nations such as Iran could be valuable and important. Objectives: The aim of this study was to assess the epidemiological, Risk factor and clinical characteristics of ischemic stroke in Ardabil province. Materials and Methods: This descriptive cross-sectional study has been done on 676 patients with ischemic stroke who referred to Ardabil city hospital during at year 2018. Data collected by using a checklist including demographic and clinical data of patients. Collected data were analyzed by statistical methods in SPSS version 21. The p-value less than 0.05 was considered as significant. Results: Of all patients, 294 (43.5%) were female and rest of them were male. The mean age of patients was 69.3±13.2 years. Of all patients, 25.3% arrived to the hospital in less than 4.5 hours. The difference between arrival time to the hospital in rural and urban patients was significant. The most risk factors were seen in both sexes was HTN and in female only was DM and in male only was CVA. The results of CT and MRI showed that 30% and 64.9% of patients had lesion respectively that of them the most lesion in MRI was SMALL VESSEL and in CT was Middle Cerebral Artery (MCA). Conclusion: Results showed that the patients who live in urban areas arrive to emergency sooner than rural patients. The significant relation was seen between AF, residence place and valvular with arriving time to hospital.

Study the frequency of bronchial anthracosis and its influencing factors in patients undergoing bronchoscopy in Ardabil city hospital, 2013-2015

Background: Bronchial anthracosis is defined as appearance of multiple dark anthracotic pigmentations on large airway mucosa with or without airway narrowing or obliteration. This study aims to investigate the frequency of bronchial anthracosis and its influencing factors in patients undergoing bronchoscopy.Methods: In this cross-sectional study, data was obtained from reviewing the files of 900 patients who underwent bronchoscopy in Ardabil city Hospital. Those with dark pigmentation on their airways mucosa were considered as having bronchial anthracosis. During bronchoscopy, samples were collected from the airways in the form of bronchoalveolar lavage and then the smear and culture of these samples were examined for acid fast bacilli. Type of fuel used for cooking in the kitchen and for heating in their house, history of smoking, the patient’s geographical location and occupation were recorded by a checklist and then evaluated.Results: Of 900 cases, 42 (4.6%) had bronchial anthracosis, out of which 23 (55%) were male and most were in urban areas. Majority of patients were in the age range of 60 to 70 years. Of 11 farmers with anthracosis, 7(6.63%) patients used fossil fuels for heating. Among the anthracosis patients, 11 (21.2%) subjects had Tuberculosis. There was a significant difference between age, habitant of patients, pulmonary tuberculosis and bronchial anthracosis.Conclusions: There was a significant correlation between age of patients, pulmonary tuberculosis and bronchial anthracosis, therefore, performing necessary tests and follow-ups for pulmonary tuberculosis is necessary in cases that undergo bronchoscopy for any reason and those with bronchial anthracosis.

Frequency, causes, and findings of brain CT scans of neonatal seizure at Ardabil City Hospital, Ardabil, Iran

Background: Neonatal seizures are the primary and most important signs of neurologic function disorders that often lead to serious complications. However, this disorder is predictable and manageable with suitable diagnostic and therapeutic methods. The aim of this study was to investigate the frequency, causes, and findings of brain CT scans of neonatal seizure.Methods: This descriptive cross-sectional study has been done on 70 neonates with seizures who hospitalized in Ardabil city hospital during 2016-2017. CT scans were done for all patients. Necessary information for each patient was recorded in a checklist including demographic data, history of diabetes mellitus, hypertension, and maternal endocrine disorders, and history of resuscitation and clinical data including type of seizure and its duration, Cause of seizure and CT scan findings (cerebral hemorrhage, local ischemic lesions, hypoxemic-ischemic encephalopathy, and anatomical cerebral malformations).Results: The mean age of neonates was 12.41±9.33 days. Of them, 61.4% were boys, 3.24% LBW and 40% were preterm at birth time. Of all neonates, 21.4% had history of seizure in their relative degree family members. Fever was the most common symptom accompanying seizures (40%). The most common form was tonic seizure (n=30, 42.9%) and its duration time was 4.99 minute. A total of 41.4% of neonates (29 cases) had abnormal CT scan reports. Hypoxic-ischemic encephalopathy (47%) was the most common findings in the CT scans of neonates with seizures.Conclusions: Results showed that, a considerable number of neonates had abnormal CT findings and the most common abnormal form was hypoxemic-ischemic encephalopathy.

Factors Affecting Unsuccessful Suicide Among Women Referred to Emergency Room of Ardabil City Hospital, Ardabil, Iran

Background: Along with the complexity of social communications, the rate of suicide is increasing, and according to studies, women commit suicide more than men. Various factors affect the occurrence of this phenomenon. The purpose of this study was to determine the factors affecting unsuccessful suicide among women referring to the emergency room of the hospital of Ardabil City, Iran. Methods: This study was a descriptive cross-sectional study conducted on 236 women who had unsuccessful suicide. Questions were asked from patients with a checklist. This checklist has four parts. The first part relates to the patient’s personal information, and the second part relates to the patient’s previous history of mental, physical, and addiction problems. The third part asked about the causes of suicide and the fourth part related to the prior announcement. The collected data were analyzed by statistical methods in SPSS v. 18. Results: The Mean±SD age of the women was 27.66±9.95 years, and the majority was between 15 and 20 years old. About 64% of women were housewives, and 37.7% had undergraduate education. Also, 36% had a positive history of psychological diseases, and 30.9% had a history of suicide. The most common causes of suicide among women were emotional problems (91.9%), family and marriage conflict (81.8%), spouse’s disregard (50.4%), and economic issues (44.5%). Conclusion: The results showed that emotional problems and family and marital conflicts were common causes of suicide among women, and all women had at least one crucial reason for their suicide attempt.

Evaluating diagnostic value of clinical symptoms and signs for chronic sinusitis by CT-scan in patients admitted to Ardabil city hospital, Iran

Background: Chronic rhinosinusitis (CRS) refers to inflammatory nasal and para nasal sinuses which last at least 12 weeks. Despite its high prevalence, it is not easy to diagnose, and clinical criteria and simple radiographs are not so sensitive. The aim of this study was to investigate the diagnostic value of clinical symptoms and signs for chronic sinusitis by Ct-scan in patients admitted to Ardabil city hospital, Iran.Methods: This descriptive cross-sectional study has been done on 83 patients with CRS symptoms who referred to ENT of Ardabil city hospital. The necessary checklist included information such as age, gender, clinical symptoms and CT scan findings were completed and analyzed by statistical methods in SPSS version 21.Results: Of all 83 patients, 55.4% were female and most of patients were in age group 30-39 years with 30.1%. Of all patients, 29 (35%) had positive findings in CT scan of which 72.4% were female. The highest rate of sinus involvement was in the ethmoid sinus. The highest positive predicted value was for nose congestion with OR=2.26 and the lowest was for facial pain and toothache each with OR=0.1.Conclusions: In general, clinical symptoms have a small predictive value in the diagnosis of sinusitis and should be evaluated with CT scan findings (15.7%).

Study complications and follow-up outcomes of preterm infants hospitalized in Ardabil city hospital in 2016

Background: Preterm birth is one of the leading and direct causes of newborn mortality. The aim of this was to study complications and follow-up outcomes of preterm infants hospitalized in Ardabil city hospital in 2016. Methodology: This cross-sectional study was conducted on 73 preterm babies at Ardabil city hospital in 2016. The research-based checklist included demographics, and the outcome data were completed through the infant’s examination and by studying hospital files. Collected data were analyzed by statistical methods in statistical package for the social sciences v.19. Results: The rate of mortality was 21.2%, and the rate of developmental disorders (DD) was 26.2%. The main preterm infant’s problems were respiratory distress syndrome (RDS) and ICTER, respectively. There was a significant inverse relation between gestational age (GA) and birth weight with the rate of mortality and developmental disorders. The relationship between sex and mortality rate was not significant. There was a significant relation between DD with RDS, age of infants, weight and round head of infants in 6 months. Conclusion: Results showed that preterm infants are at risk for DD and mortality in comparison with full-term infants. Hence, specialized care for them is essential in the future.

Epidemiological and Clinical Characteristics of Infants with Visceral Leishmaniasis hospitalized in Ardabil city Hospital during 2011-6

Epidemiological and Clinical Characteristics of Infants with Visceral Leishmaniasis hospitalized in Ardabil city Hospital during 2011-6

Relationship between migraine and hypertensive disorders of pregnancy

Aim: Preeclampsia is a pregnancy-specific syndrome associated with vascular spasm and endothelium dysfunction that leads to reduced organ blood flow. Migraine is a syndrome of benign recurrent headaches, nausea, vomiting, or other signs of neurologic dysfunction. Some studies have shown that women who have a history of migraines during pregnancy are at high risk of preeclampsia. The aim of this was determine the relation between migraine and hypertensive disorders of pregnancy. Material and Methods: In this case- control study, cases consisted of 100 women with preeclampsia, and controls were 100 normotensive women. All women were hospitalized in Ardabil city hospital and all of them were evaluated for any history of migraine. The two groups were matched for confounding factors. The data were collected by questionnaire including demographic, medical, obstetrics, and migraine assessment sections. Data were analyzed by statistical methods using SPSS version 19.Results: The mean age of women in study group was 28.12±6.50 and in control group was 25.2±5.75. Majority of persons in the study, were in age group16 to 35 years old and their education levels were high school graduates and they were housewives. The mean of BMI was 24.8. Of people, 11% were suffering from migraine. The history of migraine in the study group was 16% and in the control group was 6% and the difference was significant between two groups (p=0.001). History of migraine headaches in patients with hypertensive disorders was 2.65 times more than women in control group. Conclusion: Results showed that migraine headaches to be associated with gestational hypertension and history of any migraine could be as a risk factor for PE /gestational hypertension (GH) in future. Keywords: Gestational hypertension; migraine; preeclampsia.

Association between serum Vitamin D deficiency and Knee Osteoarthritis.

Objective: Levels of Vitamin D may influence the development of knee osteoarthritis (OA), which is one of the most common joint diseases. The aim of this study was to investigate the association between serum Vitamin D deficiency and knee OA in Ardabil and Iran.Methods:One hundred fifty-eight consecutive patients referred to rheumatology clinic of Ardabil City Hospital were recruited in the study. All the participants underwent x-rays in two anterior-posterior and side views of the knees. Staging of knee OA was done according to Kellgren-Lawrence criteria. Seventy-nine individuals with clinical and radiographic signs of knee OA were defined as the case group, and those without clinical and radiographic signs of the disease were defined as a control group. Haematology and biochemical profile including measurement of 25-hydroxyvitamin D serum level was performed in the participants.Results:The mean age of patients and controls were 54.12 ± 4.67 and 55.37 ± 5.12 years, respectively. The average serum vitamin D in OA patients and controls were 26.8±6.2 ng/ml and 28.1±5.3ng/ml, respectively (p=0.36). There was a significant association between serum vitamin D and staging of knee OA (p=0.001). Based on vitamin D levels, most of patients with vitamin D deficiency were in stages III and IV.Conclusion:The findings of the study suggest that vitamin D deficiency should be considered in patients with OA and treated accordingly.

Evaluation of brain CT-scan results and indications before lumbar puncture in children suspected of meningitis hospitalized in Ardabil city hospital

Background: Multiple use of CT scan is associated with an increased risk of cancer in the future especially in children due to cellular growth and mutation. The aim of this study was to evaluate the result and indications of brain CT scan before lumber puncture in children with suspected of meningitis.Methods: In this retrospective cross-sectional study, information of brain CT Scans on all meningitis suspected children under 12 years old hospitalized in Ardabil city hospital at 2016 who were candidates of CT Scan before Lumbar Puncture were extracted and the results were analyzed by statistical methods in SPSS version 22.Results: In this study, a total number of 67 patients were studied and CT scan changes were seen in 13 cases (19.4%) that of them 6 (46.2%) were male and rest of them were female. The mean age of the cases that had CT scan changes was 36.9±2.14 months and in other patients were 38.8±3.56 months. Of all patients, 13 patients experienced decrease in consciousness level that CT scan changes were observed in 8 cases (61.5%). Of the 13 patients (19.4%) had CT scan changes, 5 (38.4%) ha brain structural lesions.Conclusions: The prevalence rate of CT-scan changes was 19.4% and the most commonly detections in patients by CT scan, were structural disorder of the brain and subdural effusion.

The relationship between serum lactate and VO2/VCO2 in patients undergoing coronary artery bypass grafting in Ardabil city hospital, 2017

&lt;p class="abstract"&gt;&lt;strong&gt;Background:&lt;/strong&gt; VO&lt;sub&gt;2&lt;/sub&gt;/VCO&lt;sub&gt;2&lt;/sub&gt; ratio and blood lactate are different indices of adequacy of oxygen delivery to oxygen needs. The aim of this study was to investigate the relationship between serum lactate and VO&lt;sub&gt;2&lt;/sub&gt;/VCO&lt;sub&gt;2&lt;/sub&gt; in patients undergoing CABG in Ardabil city.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Methods:&lt;/strong&gt; This descriptive-analytical study was performed on 30 patients who underwent CABG at Ardabil city hospital during 2017. Demographic data of patients including age and sex were collected. Standard monitoring included electrocardiogram, invasive arterial pressure, pulse oximetry, end tidal carbon dioxide, temperature and urine output was done. The CAB was carried out through a CPB pump at the time of grafting. Blood lactate and VO&lt;sub&gt;2&lt;/sub&gt;/VCO&lt;sub&gt;2&lt;/sub&gt; were measured in 3 groups of patients based on number of grafts, EF and serum Creatinine. Collected data analyzed by statistical methods in SPSS version 19. &lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Results:&lt;/strong&gt; Most of patients were male (86.7%). The mean age of patients was 58.1 years. The blood lactate and VO&lt;sub&gt;2&lt;/sub&gt;/VCO&lt;sub&gt;2&lt;/sub&gt; values increased after surgery. There was no statistically significant difference in two groups based on number of grafts and serum Cr but it was statistically significant based on E/F. There was a significant correlation between Blood lactate and VO&lt;sub&gt;2&lt;/sub&gt;/VCO&lt;sub&gt;2&lt;/sub&gt; ratio in patients.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; The results showed that blood lactate as an indicator for patients status during CABG surgery can be replaced with VO&lt;sub&gt;2&lt;/sub&gt;/VCO&lt;sub&gt;2&lt;/sub&gt;.&lt;/p&gt;

Efficacy of Erythropoietin in treatment of anemia in patients hospitalized in the ICU of Ardabil city hospital

Background: Several studies have shown that approximately 95% of patients who have been admitted to the ICU are anemic. Anemia in acute patients leads to significant transfusion. Transfusion can lead to significant complications. Because of the risks of transfusion an alternative therapy for anemia in patients seems be a necessary need for its. The aim of this study was to investigate the efficacy of Erythropoietin in treatment of anemia in patients hospitalized in the ICU of Ardabil city hospital.Methods: This study is a clinical trial. In this study after selection of patients based on inclusion and exclusion criteria, their data were entered in a check list. Patients were divided into two groups of 35 persons randomly. For first group, erythropoietin was administrated in addition of iron and in second group only iron was administrated. All patients were administrated 100 mg of iron. Hematological indexes and clinical status of patients was evaluated and results were analyzed by statistical methods in SPSS version 19.Results: In this study, in cases 65.7% and in controls 71.4% were male. The average age of patients in cases was 61.6±20.8 and controls were 61.02±22.5 years. The mean duration of hospitalization in internal ICU was 37.73 days and in surgical ICU was 21.35 days and was observed that at baseline the hemoglobin levels in internal patients was lower than surgical patients (p=0.023). 80% of patients in case group (5.8 units) and 88.57% of patients in controls (6.3 units) required blood transfusion. The hemoglobin level in erythropoietin receiving group increased significantly compared to the control group.Conclusions: The results of this study showed that erythropoietin is an effective drug to increase hemoglobin level and can provide a significant increase in hemoglobin level compared to placebo.

Prognostic value of peripheral blood eosinophil count on first day of infancy in the incidence of neonatal hyperbilirubinemia

&lt;p class="abstract"&gt;&lt;strong&gt;Background:&lt;/strong&gt; Neonatal jaundice is one of the most common problems in the neonatal period. Eosinophilia is common in preterm and term newborns, and it is considered when the absolute count of eosinophil is ≥500 cell/mm&lt;sup&gt;3&lt;/sup&gt;. It is thought that there was some relationship between hyperbilirubinemia and increasing of blood eosinophil count in newborns hospitalized by jaundice. The aim of this study was to determine the prognostic value of peripheral blood eosinophil count on first day of infancy in the incidence of neonatal hyperbilirubinemia.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Methods:&lt;/strong&gt; 150 newborns with gestational ages of 35-40 weeks, born in Ardabil city hospital, were engaged in this study. After obtaining the parents' consent, getting patients biography and their physical examination, we got a blood sample from umbilical cord of newborns to measure differential count of white blood cells. The neonates were observed up to 28 day followed. Then, second blood test conducted for the purpose of measuring serum level of bilirubin. Data were analyzed by statistical methods in SPSS version 19. &lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Results:&lt;/strong&gt; Various group of age, sex, blood type and gestational age showed no significant difference in their eosinophil rate. Total serum bilirubin doesn't had a significant relationship with gestational age, sex, type of delivery and major or minor blood groups of neonates.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; Results showed that there was no significant relationship between the amount of eosinophil in newborn umbilical cord and total serum bilirubin. So, we could say that newborns eosinophil count isn’t a good criteria for predicating the appearance of neonate hyperbilirubinemia.&lt;/p&gt;

Study frequency of ABO and RH in patients with acute coronary syndrome referred to Ardabil city hospital

&lt;p class="abstract"&gt;&lt;strong&gt;Background:&lt;/strong&gt; Regarding the high prevalence, the increasing trend of acute coronary syndrome (ACS), the importance of etiological studies of diseases and the existence of some reports on the role of blood groups in the development of diseases, including IHD, in order to study the blood groups in patients with acute coronary syndrome and other factors, this research was conducted in Ardabil.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Methods:&lt;/strong&gt; This is a descriptive study that was carried out from March 2016 to May 2017 in a Hospital of Ardabil on 500 patients selected randomly from patients admitted to cardiac care unit of Hospital. The criteria for entering the study were: All subjects over the age of 30 and both sexes were males and females who had myocardial infarction (MI), unstable angina (UA) based on history, examination, serial electrocardiography and measurement cardiac enzymes are given by a specialist physician and they are willing to participate in the study. Then, in the checklist for each patient, the blood type ABO and RH, the age, sex, and risk factors of the disease such as hypertension, diabetes, obesity, consumption smoking, high blood lipids, and family history of premature stenosis were extracted from the patient records and then analyzes by statistical methods in SPSS.19. &lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Results:&lt;/strong&gt; Of all patients, 60.2% were male and the mean age was 62.28 years. Hypertension with 61.6%, smoking with 37.4%, and hyperlipidemia with 23.4% were the most common risk factors among patients. The blood groups A and A+ were the most common type of blood type, but due to the higher prevalence of A blood group in healthy individuals living in Ardabil, there was no significant relation between ACS and blood groups.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; Results showed that blood groups did not show a meaningful relationship with the incidence of ACS and did not find any association between severity of this syndrome and blood groups.&lt;/p&gt;