To evaluate the Effectiveness of coatings in reducing biofilm adhesion on arch wire. A literature search was performed on PubMed, Medline, Google Scholar, and Science Direct to examine studies that compared the uncoated group of arch wires to those with nano coatings and assessed the anti-adherent property. After extracting the data from each study, two risk of bias assessment tools were employed and tabulated data was obtained. 8 Studies met the requirements for inclusion. For majority of the included articles, the risk of bias assessment indicated a low to moderate risk. The antibacterial properties of various nanoparticle coatings were examined and evaluated.Regardless of patient compliance, a proper application of each type of coated arch-wire can help prevent white spot lesions and reduce bacterial aggregation around orthodontic attachments. Majority of the studies that made up this systematic review have a risk of bias grade of "fair." A meta-analysis was not feasible because of heterogeneity in the different coating techniques used to test the antibacterial property.
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