Chemical Modification Approaches Research Articles

Acetylation of wood: understanding the risk of de-acetylation during exposure to elevated temperature

Abstract Acetylation is a breakthrough in wood modification and has been established on industrial scale. However, concerns have been raised regarding the stability of acetylated wood under elevated temperatures, particularly during post hot-pressing processes to manufacture products such as laminated veneer lumber (LVL). At around 150 °C, the added acetyl groups might cleave off (“de-acetylation”) and by that release sorption sites for water. This would increase the moisture uptake of the modified wood. In this study, the impact of hot-pressing at 150 °C on the stability of acetylated beech veneers and LVL was investigated. Fourier transform infrared (FTIR) spectroscopy showed that the chemical composition of acetylated veneers seemed to be unaffected after the heat treatment. Dynamic vapor sorption (DVS) analysis and long-term storing over saturated salt-solutions in miniature climate chambers, indicated no de-acetylation on the basis of negligible changes in wood-water interactions. The number of hydroxyl groups of heat-treated acetylated samples was similar to that of not heat-treated ones, indicating the persistence of the effects of acetylation. By the present study, a certain resilience of acetylated wood towards elevated temperature, like it may occur during hot-pressing of acetylated veneers, became apparent and illustrated the thermal stability of this chemical modification approach.

Enhancing durability of superhydrophobic surfaces via nanoparticle-induced bipolar interface effects and micro-nano composite structures: A femtosecond laser and chemical modification approach

Superhydrophobic coatings are vital in energy, aerospace, and chemical engineering, while their complex preparation and limited durability hinder widespread application. Therefore, inspired by the unique structures of hydrophobic cotton surfaces and mosquito eyes in nature, a durable aluminum alloy superhydrophobic surface is developed using a combination of femtosecond laser and chemical modification methods. Initially, porous microneedle micro-nanostructures are ablated on the surface of the aluminum alloy via femtosecond laser technology. Then, epoxy resin modified with γ-aminopropyl triethoxysilane (KH550) forms a covalently bonded intermediate layer. Finally, biphasic silicon dioxide (BP-SiO2) nanoparticles modified by hexadecyltrimethoxysilane (HDTMS) are used to construct the top hydrophobic layer. The covalent interface interactions between the aluminum alloy substrate and the intermediate layer, as well as between the intermediate layer and the top layer, significantly enhance the durability of the superhydrophobic surface. The prepared F-M@KH-EP/BP-SiO2 coating exhibits outstanding superhydrophobic properties, with a water contact angle (CA) as high as 168.56° and a sliding angle (SA) as low as 1.52° More encouragingly, the composite coating maintains its excellent water resistance even when subjected to harsh mechanical durability damage, including sandpaper wear, tape stripping tests, water drop and sand impact tests. Moreover, the prepared coatings maintain distinguished non-wettability in harsh operating conditions such as corrosive liquid environments, ultraviolet radiation, ultrasonic vibration, etc. Additionally, the coating demonstrates remarkable self-cleaning properties. Superhydrophobic surface durability is significantly enhanced by combining nanoparticle-induced bipolar interface effect and micro-nano structures. These findings provide theoretical reference for the design and application of durable superhydrophobic coatings.

Silk fibroin catheter with stable bioinspired inner-surfaces for inhibition of bioadhesion

Biofilm formation on indwelling medical devices such as catheters and ventilators due to the adhesion of bacteria poses significant challenges in healthcare. Surface modification with micro- and nano-structures offers a promising strategy to prevent bioadhesion and is safer than surface chemical modification approaches. Here, catheters were prepared using silk fibroin (SF) hydrogels and an infusion molding method, with the inner surface featuring a micropapillae structure inspired by lotus leaves (SF-CMP). After phenylethanol (PEA) fumigation treatment, the resulting catheters (SF-CMP PEA) displayed improved swelling resistance and mechanical properties compared to methanol-treated catheters (SF-CMP MeOH). PEA was more efficient than methanol in controlling the size, distribution, and content of silk crystalline β-sheet blocks and thus the swelling and mechanical properties. Moreover, the micro-papillae structure on SF-CMP PEA remained stable over 35 days in solution, in contrast to SF-CMP MeOH, which lasted <7 days. SF-CMP PEA exhibited repellent effects against E. coli and S. aureusin vitro, and low cytotoxicity to the endothelial cells cultured on the unpatterned surface. Additionally, subcutaneous implantation studies showed reduced inflammation around the micropatterned samples compared to controls with a plain, unpatterned surface. The unique properties of SF-based materials, including tunable structures, biocompatibility, degradation, and drug-loading capability make them an attractive material for anti-bioadhesion in applications ranging from indwelling medical devices to tissue engineering scaffolds.

Aminolysis-Based Zwitterionic Immobilization on Polyethersulfone Membranes for Enhanced Hemocompatibility: Experimental, Computational, and Ex Vivo Investigations.

Dialysis membranes are not hemocompatible with human blood, as the patients are suffering from the blood-membrane interactions' side effects. Zwitterionic structures have shown improved hemocompatibility; however, their complicated synthesis hinders their commercialization. The goal of the study is to achieve fast functionalization for carboxybetaine and sulfobetaine zwitterionic immobilization on PES membranes while comparing the stability and the targeted hemocompatibility. The chemical modification approach is based on an aminolysis reaction. Characterization, computational simulations, and clinical analysis were conducted to study the modified membranes. Atomic force microscopy (AFM) patterns showed a lower mean roughness for carboxybetaine-modified (6.3 nm) and sulfobetaine-modified (7.7 nm) membranes compared to the neat membrane (52.61 nm). The pore size of the membranes was reduced from values above 50 nm for the neat PES to values between 2 and 50 nm for zwitterionized membranes, using Brunauer-Emmett-Teller (BET) analysis. More hydrophilic surfaces led to a growth equilibrium water content (EWC) of nearly 6% for carboxybetaine and 10% for sulfobetaine-modified membranes. Differential scanning calorimetry (DSC) measurements were 12% and 16% stable water for carboxybetaine- and sulfobetaine-modified membranes, respectively. Sulfobetaine membranes showed better compatibility with blood with respect to C5a, IL-1a, and IL-6 biomarkers. Aminolysis-based zwitterionization was found to be suitable for the improvement of hemodialysis membranes. The approach introduced in this paper could be used to modify the current dialysis membranes with minimal change in the production facilities.

Covalent vs. Non covalent chemical modification of multiwalled carbon nanotubes based-nanofluids: Stability and thermal conductivity steadiness over temperature

Thermal conductivity enhancement coupled to nanoparticle dispersion stability over time are the two main conflicting requirements to overcome to develop carbon nanomaterial-based nanofluids. Both covalent and non-covalent approaches, having their own advantages and disadvantages, are commonly used for carbon nanotube based nanofluids development. However, they are rarely compared regarding their impact on stability and thermal conductivity performances for the same kind of nanofluid. In this work, multiwalled carbon nanotubes have been chemically modified by both covalent and non-covalent functionalization. For the covalent functionalization, a simple oxidation method is applied. It consists of refluxing the powdered MWCNTs in H2SO4/HNO3 at 5 M concentration. For the non-covalent approach, both an anionic (sodium dodecyl sulfate) and a non-ionic (Pluronic P123, comprising poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) in an alternating linear fashion, PEO-PPO-PEO) surfactants were employed at a concentration of 1 wt%. Nanofluids were prepared with multiwalled carbon nanotubes at a fixed concentration of 0.2 wt% for both chemical modification approaches. The oxidation reaction occurs without significant structure damaging as shown by transmission electron microscopy, Raman spectroscopy, Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. UV–visible spectrophotometry analysis shows a remarkable stability with temperature in the 293.15–303.15 K range over one-week and for a longer period of 49 days for all the three types of nanofluids. Their thermal conductivity has been investigated in the same temperature range. For all the three nanofluid series prepared with a fixed concentration of carbon nanomaterials, a thermal conductivity enhancement compared to that of the base fluid has been observed. The thermal conductivity evolution with temperature is different for each type of nanofluid. The covalently oxidized multiwalled carbon nanotube based nanofluids showed the better thermal conductivity enhancement steadiness (around 7 %) with temperature. The discussion on the surfactant-based nanofluid behavior proposes the possible involved mechanisms as temperature increases for each surfactant.

PrBaFe2O6-δ-based composites as promising electrode materials for protonic ceramic electrochemical cells

PrBaFe2O6–δ (PBF) is considered as a promising material for mixed ionic-electronic conductors used in high-temperature applications. In the present work, PBF was used as a basis for two chemical modification approaches, including doping with cobalt, nickel and copper, as well as composite design with the addition of a BaCe0.8Sm0.2O3–δ phase. The single-phase and composite materials were successfully prepared and characterized in terms of their functional properties. The two approaches were found to synergistically affect the functional properties of PBF, allowing a trade-off between thermomechanical and transport properties to be achieved. As a result, the prepared 70 wt% PrBaFe1.9M0.1O6–δ (M = Co, Ni, Cu) + 30 wt% BaCe0.8Sm0.2O3–δ composites exhibit acceptable electrochemical activity in the intermediate-temperature range. The best electrochemical activity was found for the sample with M = Cu, whose polarization resistance at 700 °C reaches 1.7 Ω cm2. Therefore, the designed PBF-based composites can be considered as promising electrode materials for solid oxide fuel cell applications.

A redox-responsive prodrug for tumor-targeted glutamine restriction

Modulating the metabolism of cancer cells, immune cells, or both is a promising strategy to potentiate cancer immunotherapy in the nutrient-competitive tumor microenvironment. Glutamine has emerged as an ideal target as cancer cells highly rely on glutamine for replenishing the tricarboxylic acid cycle in the process of aerobic glycolysis. However, non-specific glutamine restriction may induce adverse effects in unconcerned tissues and therefore glutamine inhibitors have achieved limited success in the clinic so far. Here we report the synthesis and evaluation of a redox-responsive prodrug of 6-Diazo-5-oxo-L-norleucine (redox-DON) for tumor-targeted glutamine inhibition. When applied to treat mice bearing subcutaneous CT26 mouse colon carcinoma, redox-DON exhibited equivalent antitumor efficacy but a greatly improved safety profile, particularly, in spleen and gastrointestinal tract, as compared to the state-of-the-art DON prodrug, JHU083. Furthermore, redox-DON synergized with checkpoint blockade antibodies leading to durable cures in tumor-bearing mice. Our results suggest that redox-DON is a safe and effective therapeutic for tumor-targeted glutamine inhibition showing promise for enhanced metabolic modulatory immunotherapy. The approach of reversible chemical modification may be generalized to other metabolic modulatory drugs that suffer from overt toxicity.

Lignin nanoparticles as a promising nanomaterial for encapsulation of Rose damascene essential oil: Physicochemical, structural, antimicrobial and in-vitro release properties

Lignin is the second most abundant biopolymer, suitable for use as a raw material in various industries due to its low cost and inherent properties. The development of lignin nanoparticles (LNPs) can provide an innovative way to utilize lignin for high-value applications. The food industry is seeking to utilize LNPs for various purposes such as dietary supplements, carriers, and preservatives due to their exceptional biodegradability and biocompatibility. This study aimed to prepare LNPs for the encapsulation of Rosa damascena essential oil (REO) to enhance the protection of this bioactive compound under storage conditions and control its release in contact with foodstuff conditions. Alkali lignin was used for the preparation of LNPs through an anti-solvent method and no chemical modification approach was used for their stabilization. The effect of the REO:LNP mass ratio on the physicochemical and structural properties of the encapsulated essential oil (REO-LNPs) was investigated. The REO-LNP sample with a mass ratio of 0.2:1.0 showed excellent physical properties with a zeta potential of −45 mV, a diameter of 119.7 ± 1.4 nm, moderate polydispersity (0.087 ± 0.014) and high encapsulation efficiency (99.63%). The stability assay of REO-LNP demonstrated enhanced protection of the entrapped REO under storage conditions. Subsequently, the morphological, thermal, antioxidant, antimicrobial, and in vitro release properties of the REO-LNP were determined. The thermogravimetric analysis (TGA) showed that the REO-LNP has a significantly higher thermal stability than free REO. The inclusion of REO in LNPs led to an enhancement of the antioxidant activity of REO. Compared to REO, REO-LNPs exhibited improved antibacterial properties against both S. aureus and E. coli. The REO-LNP demonstrated lower release in aqueous food simulant, and the Ritger-Peppas model showed that the Fickian diffusion mechanism occurred, which was caused by the poor swelling degree and presence of oils at the surface of nano-capsules. In vitro cell viability evaluation showed that the prepared samples had no cytotoxicity and excellent biocompatibility with normal human fibroblast cells. Overall, LNPs can be proposed as renewable nanocarriers for the protection and controlled release of natural antioxidants/antibacterials such as REO in multifunctional applications.

Chemical doping-assisted shape transformation of block copolymer particles

Iodine-mediated chemical modification approach was developed for the facile shape transformation of block copolymer colloidal particles.

IMPROVEMENT OF SAWDUST FIBER IN PROPERTIES OF POLYLACTIC ACID COMPOSITES: EFFECT OF FIBER SURFACE TREATMENTS

In this study, we investigated the impact of surface treatment on polylactic acid (PLA)/sawdust fiber (SF) composites. Utilizing a 20&amp;#37; weight-to-weight ratio of agricultural waste, three distinct chemical modification approaches were employed to treat the sawdust, with the aim of enhancing the compatibility between the PLA matrix and the wood fibers. The treatments included alkali-, benzoyl chloride-, and permanganate-treated SFs. The results demonstrated an increase in rigidity with alkali treatment, while composites treated with benzoyl chloride and permanganate exhibited improved ductility. However, the thermal stability of the treated fiber composites was reduced. Comparative analysis revealed that wood fibers treated with sodium hydroxide and permanganates exhibited superior dispersion in the PLA matrix compared to fibers treated with benzoyl chloride. Beyond these findings, this assessment carries significant implications for sustainable material development, since the utilization of agricultural waste provides an alternative composite material for construction or industrial applications. The study's outcomes contribute to the ongoing quest for eco-friendly solutions in material science and offer practical insights for selecting the most suitable composite material based on specific applications and industry needs.

Using recycled gangue to capture CO2 and prepare alkali-activated backfill paste: Adsorption and microevolution mechanisms

Gangue is a type of coal-based solid waste that can be used to prepare mine backfill and CO2 capture materials. However, the CO2 capture ability and activity of gangue are limited by its natural unreactive minerals and dense micro-structure. This study developed a novel chemical modification approach to modify recycled gangue and enhance its CO2 capture and hydration properties. Moreover, a new type of recycled gangue-based backfill paste was prepared to capture CO2. Multiple experiments were conducted to characterize the CO2 capture ability, mineral composition, and specific surface area of the modified gangue, as well as the hydration and microstructure of the alkali-activated modified gangue-based paste (ACM). The results reveal that the CO2 adsorbed ability and compressive strength of ACM can be significantly improved via acetic acid (AA) modification, and the optimum dosage of AA is 2 wt% of the gangue. At this dosage, the CO2 capture ability of gangue reaches 0.30 mmol/g, and the 3 d compressive strength of the ACM is doubled. This is because of the following reasons: 1) AA reacts with kaolinite and muscovite to generate acetate, which increases gangue activity; 2) the modification reduces the particle size and increases the specific surface area of the gangue, both of which are crucial for improving the CO2 capture capacity of the gangue. 3) More gels are generated in ACM, and the dense microstructure contributes to an increase in the compressive strength. This study develops an effective approach to improve the activity and CO2 capture ability of recycled gangue and thus provides guidance for backfill mining, recycled gangue utilization, and CO2 capture.

Surface modification of Nano cellulose: The path to advanced uses of smart and sustainable bio-material

In order to develop sophisticated applications for intelligent and sustainable biomaterials, our work focuses on the surface modification of nanocellulose. Nanocellulose has the ability to be modified to improve its surface characteristics, making it appropriate for a variety of uses in industries including biomedicine, packaging, textiles, and water treatment. There have been discussions on a number of physical and chemical surface modification approaches, including mechanical treatment, high-pressure homogenization, and chemical functionalization. The study also highlights the results of different characterization methods that were employed to examine the surface-modified nanocellulose. The review addresses the difficulties in integrating nanocellulose into many applications, despite its potential, including manufacturing scale-up, standardisation, and toxicity issues. The article's conclusion highlights the need for continuing research and development of nanocellulose-based materials in order to meet these obstacles and offer long-term solutions to a range of social issues.

Ionizing and nonionizing radiations can change physicochemical, technofunctional, and nutritional attributes of starch.

Challenges for the food/non-food applications of starch mostly arise from its low stability against severe processing conditions (i.e. elevated temperatures, pH variations, intense shear forces), inordinate retrogradability, as well as restricted applicability. These drawbacks have been addressed through the modification of starch. The escalating awareness of individuals toward the presumptive side effects of chemical modification approaches has engrossed the attention of scientists to the development of physical modification procedures. In this regard, starch treatment via ionizing (i.e. gamma, electron beam, and X-rays) and non-ionizing (microwave, radiofrequency, infrared, ultraviolet) radiations has been introduced as a potent physical strategy offering new outstanding attributes to the modified product. Ionizing radiations, through dose-dependent pathways, are able to provoke depolymerization or cross-linking/grafting reactions to the starch medium. While non-ionizing radiations could modify the starch attributes by changing the morphology/architecture of granules and inducing reorientation/rearrangement in the molecular order of starch amorphous/crystalline fractions.

Drug Delivery through Epidermal Tissue Cells by Functionalized Biosilica from Diatom Microalgae.

Diatom microalgae are a natural source of fossil biosilica shells, namely the diatomaceous earth (DE), abundantly available at low cost. High surface area, mesoporosity and biocompatibility, as well as the availability of a variety of approaches for surface chemical modification, make DE highly profitable as a nanostructured material for drug delivery applications. Despite this, the studies reported so far in the literature are generally limited to the development of biohybrid systems for drug delivery by oral or parenteral administration. Here we demonstrate the suitability of diatomaceous earth properly functionalized on the surface with n-octyl chains as an efficient system for local drug delivery to skin tissues. Naproxen was selected as a non-steroidal anti-inflammatory model drug for experiments performed both in vitro by immersion of the drug-loaded DE in an artificial sweat solution and, for the first time, by trans-epidermal drug permeation through a 3D-organotypic tissue that better mimics the in vivo permeation mechanism of drugs in human skin tissues. Octyl chains were demonstrated to both favour the DE adhesion onto porcine skin tissues and to control the gradual release and the trans-epidermal permeation of Naproxen within 24 h of the beginning of experiments. The evidence of the viability of human epithelial cells after permeation of the drug released from diatomaceous earth, also confirmed the biocompatibility with human skin of both Naproxen and mesoporous biosilica from diatom microalgae, disclosing promising applications of these drug-delivery systems for therapies of skin diseases.

Advanced Metallized Nanofibers for Biomedical Applications.

Nanofibers are long, wire-like materials with nanoscale diameters and specific length diameter ratios. Nanofibers have porous reticular networks with remarkably high specific surface areas and significant interconnectivity between pores, allowing for the chemical modification and loading of drugs. Metallized nanofibers are novel materials that enhance the performance of attributes of conventional nanofibers by combining metals with nanofibers through electrostatic spinning doping, chemical modification, and loading approaches. Due to their unique physical and chemical properties, metallized nanofibers are diverse, rapidly developed materials in the fields of physical chemistry, materials science, and battery preparation. To date, with improvement in advanced preparation techniques and biocompatibility levels for materials, metallized nanofiber applications are gradually expanding into the biomedical field due to their excellent thermal and electrical conductivities and unique metal properties. In this review, the applications of metallized nanofibers in biomedicine are summarized. It is suggested to prepare metallized multifunctional nanofibers for tissue engineering, drug delivery, tumor treatment, wound healing, and biosensing applications by taking safety and stability as the main material selection guidelines. Finally, the development of nanofibers for biomedical applications is summarized and discussed.

Deep insights into kinetics, optimization and thermodynamic estimates of methylene blue adsorption from aqueous solution onto coffee husk (Coffee arabica) activated carbon

In the current study, an attempt was made to synthesize coffee husk (CH) activated carbon by chemical modification approach (sulphuric acid-activated CH (SACH) activated carbon) and was used as a valuable and economical sorbent for plausible remediation of Methylene blue (MB) dye. Batch mode trials were carried out by carefully varying the batch experimental variables: SACH activated carbon (SACH AC) dosage, pH, initial dye concentration, temperature, and contact time. The optimum equilibrium time for adsorption by SACH activated carbon was obtained as 60 min, and the maximum adsorption took place at 30 °C. Morphological and elemental composition, crystallinity behaviour, functional groups, and thermal stability were examined using SEM with EDX, XRD, FTIR, BET, TGA, and DTA and these tests showed successful production of activated carbon. The outcomes showed that chemical activation enhanced the number of pores and roughness which possibly maximized the adsorptive potential of coffee husk. The Box-Benken design (BBD) was used to optimize the MB dye adsorption studies and 99.48% MB dye removed at SACH AC dosage of 4.83 g/L at 30 °C for 60 min and pH 8.12, and the maximum adsorption was yielded for sulphuric acid-activated coffee husk carbon carbon with 88.1 mg/g maximum MB adsorption capacity. Langmuir- Freundlich model deliberately provided a better fit to the equilibrium data. The SACH AC-MB dye system kinetics showed a high goodness-of-fit with pseudo second order model, compared to other studied models. Change in Gibbs's free energy (ΔGo) of the system indicated spontaneity whereas low entropy value (ΔSo) suggested that the removal of MB dye on the SACH activated carbon was an enthalpy-driven process. The exothermic nature of the sorption cycle was affirmed by the negative enthalpy value (ΔHo). The adsorptive-desorptive studies reveal that SACH AC could be restored with the maximum adsorption efficiency being conserved after the fifth cycles. Overall, the outcomes revealed that sulphuric acid-activated coffee husk activated carbon (SACH AC) can be used as prompt alternative for low-cost sorbent for treating dye-laden synthetic wastewaters.

Protein Modification via Nitrile Oxide-Dehydroalanine Cycloaddition: Formation of Isoxazoline Ring on the Protein Backbone.

Here we describe a novel catalyst-free 1,3-dipolar cycloaddition bioconjugation approach for chemical modification of proteins. The dehydroalanine (Dha)-containing protein reacts with nitrile oxides generated in situ through 1,3-dipolar cycloaddition in fully aqueous-buffered systems. This leads to the formation of a new isoxazoline ring at a pre-defined site (Dha) of the protein. Furthermore, the 1-pyrene isoxazoline-installed annexin V acts as a fluorescent probe, which successfully labels the outer cellular membranes of human cholangiocarcinoma (HuCCA-1) cells for detection of apoptosis.

High-efficiency recovery of cerium ions from monazite leach liquor by polyamines and polycarboxylates chitosan sorbents prepared from marine industrial wastes

Rare earth elements have received a lot of attention in recent years due to their increasing demand in high-tech industries. Cerium is of current interest and is commonly used in different industries and medical applications. Cerium's uses are expanding due to its superior chemical characteristics over other metals. In this study, different functionalized chitosan macromolecule sorbents were developed from shrimp waste for cerium recovery from a leached monazite liquor. The process involves demineralization, deproteinization, deacetylation, and chemical modification steps. A new class of two-multi-dentate nitrogen and nitrogen‑oxygen donor ligand-based macromolecule biosorbents was synthesized and characterized for cerium biosorption. The crosslinked chitosan/epichlorohydrin, chitosan/polyamines, and chitosan/polycarboxylate biosorbents have been produced from marine industrial waste (shrimp waste) using a chemical modification approach. The produced biosorbents were used to recover cerium ions from aqueous mediums. The affinity of the adsorbents towards cerium was tested in batch systems under different experimental conditions. The biosorbents showed high affinities for cerium ions. The percentage of cerium ions removed (%) from its aqueous system by polyamines and polycarboxylate chitosan sorbents is 85.73 and 90.92 %, respectively. The results indicated that the biosorbents have a high biosorption capacity for cerium ions from aqueous and leach liquor streams.

Intracellular delivery of therapeutic proteins. New advancements and future directions.

Achieving the full potential of therapeutic proteins to access and target intracellular receptors will have enormous benefits in advancing human health and fighting disease. Existing strategies for intracellular protein delivery, such as chemical modification and nanocarrier-based protein delivery approaches, have shown promise but with limited efficiency and safety concerns. The development of more effective and versatile delivery tools is crucial for the safe and effective use of protein drugs. Nanosystems that can trigger endocytosis and endosomal disruption, or directly deliver proteins into the cytosol, are essential for successful therapeutic effects. This article aims to provide a brief overview of the current methods for intracellular protein delivery to mammalian cells, highlighting current challenges, new developments, and future research opportunities.

Influence of chemical modification approaches on physicochemical and structural properties of dietary fiber from oat

The effects of carboxymethylation (CM), hydroxypropylation (HP), and cross-linking (CL) on the physicochemical, thermal, and microstructural properties of oat dietary fiber (ODF) were investigated. ODF extracted from defatted oat flour had 66.14% total dietary fiber, 3.42% protein, 5.15% ash, and 1.86% starch. Chemical modifications (CM, HP, CL) significantly improved the SDF but decreased the IDF content of ODF. Results displayed that all the chemical treatments significantly (p < 0.05) improved the swelling capacity, oil absorption capacity, and water absorption capacity of ODF with carboxymethylation being the highly influential. The CM significantly increased the solubility (7.15%), while CL (4.78%) and HP (4.17%) significantly (p < 0.05) decreased the solubility of ODF. The color evaluation showed a decrease in the L* value of ODF after all three modifications, resulting in an increase in the brown color of ODF. XRD results demonstrated an increase in the crystallinity value of ODF after these modifications (19.23–28.94%). DSC results reflected an increase in decomposition/peak temperature of cross-linked ODF showing enhanced thermal stability of such type of modified DF. The changes in physicochemical, microstructural, and thermal properties of ODF after chemical modifications could be attributed to the variations in chemical composition and structure as demonstrated by XRD, FTIR, and SEM analysis.