Abstract: A significant challenge in women’s health is posed by Polycystic Ovary Syndrome (PCOS) because it is a difficult disorder to comprehend and exhibits various symptoms. Thisresearch project suggests the creation of a computerized prediction scheme for PCOS using machine learning algorithms and bioinformatics tools. The aim of this system is to give personalized risk assessment to women thus enabling early detection, and proactive management of PCOS. It combines other intelligible probabilities about PCOS with the use of user provided health data with Machine Learning models such as Random Forest, Logistic Regression, Support Vector Machine, Naive Bayes, Radial SVM, Linear SVM and KNeighbours Classifier. Additionally, it provides intuitive predictions regarding PCOS likelihood through ML models, which are based on Random Forest, Logistic Regression, Support Vector Machine (SVM), Naive Bayes (NB), Radial SVM (RSVM), Linear SVM (LSVM) and KNeighbours Classifier (KNC). By way of thorough assessment as well as comparison within these models the system intends to improve precision together with reliability during prediction of PCOS. The major objective is therefore to enable timely intervention along with individualized healthcare strategies that will promote better health outcomes for all women.