Applications Of Hypervalent Iodine Reagents Research Articles

Azidation with Hypervalent Iodine Reagents

AbstractIn this short review, we describe applications of hypervalent iodine reagents for the azidation of organic compounds from seminal publications to the most recent reports. After reviewing selected examples of azidations based on the use of in situ formed unstable non-cyclic reagents, we focus in more detail on stable cyclic hypervalent iodine reagents. Important advances in the azidation of C–H bonds, alkenes, as well as other transformations are described. Rather than being comprehensive, we highlight selected key reports that, in our opinion, especially contributed to the advancement of research in the field.1 Introduction2 Non-Cyclic λ3-Iodanes3 Heterocyclic λ3-Iodanes3.1 Azidation of Aliphatic C–H Bonds3.2 Azidation of Alkenes3.3 Other Azidations4 Conclusion and Outlook

Recent Advances in Organic Electrochemical Synthesis and Application of Hypervalent Iodine Reagents

Recent Advances in Organic Electrochemical Synthesis and Application of Hypervalent Iodine Reagents

Iodanes as Trifluoromethylation Reagents.

This chapter describes synthesis, structural properties, activation modes, and applications of hypervalent iodine reagents for trifluoromethylation, thereby focusing on recent advances.

ChemInform Abstract: Hypervalent Iodine Reagents in the Total Synthesis of Natural Products

AbstractReview: 445 refs.

Hypervalent iodine reagents in the total synthesis of natural products

Covering: 2008–2010 This report describes the recent applications of hypervalent iodine reagents in the total synthesis of natural products. The large diversity of high-yielding and chemoselective reactions that can be achieved, even for highly functionalized molecules, is summarized, demonstrating that hypervalent iodine reagents have become an essential tool in synthetic organic chemistry.

Hypervalent Iodine Chemistry in Synthesis: Scope and New Directions

AbstractFor Abstract see ChemInform Abstract in Full Text.

Hypervalent Iodine and Carbohydrates – A New Liaison

Synthetic applications of hypervalent iodine reagents in the oxidation state +3 in relation to unsaturated carbohydrates are reviewed. By using the Koser reagent or its bis(azido) derivative, fully protected glycals are oxidatively deblocked in the allylic position. The reaction furnishes carbohydrate-derived 2,3-dihydro-4H-pyranones, which serve as starting materials for the preparation of C-saccharides, glycosyl stannanes or thromboxane A2-analogues. Alternatively, iodine(III) reagents can be used to oxidize halide anions. The halogen-ate complexes thus generated behave like synthetic equivalents of acyl hypobromite and iodite, respectively, or halogen azides, which can all add to alkenes, including glycals, under very mild conditions.

Hypervalent Iodine and Carbohydrates – A New Liaison

Synthetic applications of hypervalent iodine reagents in the oxidation state +3 in relation to unsaturated carbohydrates are reviewed. By using the Koser reagent or its bis(azido) derivative, fully protected glycals are oxidatively deblocked in the allylic position. The reaction furnishes carbohydrate-derived 2,3-dihydro-4H-pyranones, which serve as starting materials for the preparation of C-saccharides, glycosyl stannanes or thromboxane A2-analogues. Alternatively, iodine(III) reagents can be used to oxidize halide anions. The halogen-ate complexes thus generated behave like synthetic equivalents of acyl hypobromite and iodite, respectively, or halogen azides, which can all add to alkenes, including glycals, under very mild conditions.

ChemInform Abstract: Application of Hypervalent Iodine Reagents to the Synthesis of Aminophosphonic Acids.

AbstractBecause of their easy preparation and stability the iodine reagents shown in the condition A) and B) are applied to the Hofmann degradation.

Application of hypervalent iodine reagents to the Synthesis of Aminophosphonic Acids

Application of hypervalent iodine reagents to the Synthesis of Aminophosphonic Acids