Application Of Ultrasound Biomicroscopy Research Articles

Application of Ultrasound Biomicroscopy in Longterm Follow-up Post Modified CO2 Laser-assisted Sclerectomy Surgery

Objective To observe the role of ultrasound biomicroscopy(UBM)in two-year post-operative follow-up for primary open-angle glaucoma patients with modified CO2 laser-assisted sclerectomy surgery(CLASS).Methods This was a case series study.A combination of modified CLASS and preoperative laser iris management was administered to 28 eyes.Visual acuity,intraocular pressure(IOP),and slit-lamp examinations,visual field testing,and gonioscopy were carried out at baseline and until 24 months postoperatively.UBM examination was performed at 1,3,12 and 24 months postoperatively.Results Compared with the mean preoperative IOP [(30.61±10.59)mmHg],the IOP at each time point after operation was significantly lowered [(15.15±5.87),(12.56±3.24),(13.15±2.73),(13.75±2.55)and(13.75±2.46)mmHg at 1,3,6,12 and 24 months,respectively;all P<0.001].Complete success rates and qualified success rates at 12 months and 24 months were 60.71%,89.29% and 53.57%,85.71%,respectively.UBM images can present "dolphin head sign" after successful CLASS.The thickness of trabeculo-Descemet's window was(0.13±0.03)mm,which had no significant correlation with postoperative IOP at 12(r=-0.278,P=0.144)and 24 months(r=0.026,P=0.895).UBM examination revealed a severe scleral lake diminution(a change > 50%)in 1 eye(3.57%)at 12 months and 3 eyes(10.71%)at 24 months.There was no statistical significance detected between the size of the scleral lake and IOP after CLASS.Non-founctional blebs were found in 16 eyes(57.14%)at 12 months and 25 eyes(89.28%)at 24 months.Two eyes(7.14%)demonstrated severe peripheral anterior synechiae at 24 months,requiring surgical intervention.Conclusions UBM can effectively observe the morphology of the scleral lake,anterior chamber angle and filtering blebs in post-operative follow-up after modified CLASS,and give early warning of complications.It plays an important role in ensuring the success of CLASS.

Possibilities of ultrasound methods in diagnostics of eyelid tumors

To determine the informative value of ultrasound biomicroscopy (UBM) with A-scan for assessment of qualitative and quantitative characteristics of eyelid tumors less than 5 mm in size. The study included 25 patients (25 eyes) with eyelid tumors less than 5 mm in size. In addition to standard ophthalmic examination, complex ultrasound diagnostics including B-scan, Color Doppler imaging and UBM with A-scan were performed. The localization, size, structure of eyelid tumors and the state of perifocal tissues were evaluated. All patients underwent surgical treatment with following histological examinations of dissected tissues. Due to qualitative analysis of the studied formations and small number of included patients, there was no need in statistical analysis of the data. Complex application of UBM and A-scan allowed specifying the localization, size, structure of the small-sized tumors and detecting typical echographic signs of benign or malignant properties of the pathological process. Ultrasound data (UBM and A-scan) of eyelid tumors was highly correlated to histological features. UBM with A-scan can be recommended for differential diagnostics of small-sized tumors and optimizing their management.

The application of ultrasound biomicroscopy in pterygium surgery

Objective To observe the guidance role of ultrasound biomicroscope (UBM) examination results for pterygium operation. Methods Eighty-five eyes of 85 cases with primary pterygium were randomly divided into clinical trial group, 46 eyes, using UBM examination results for guiding the pterygium operation; and the control group, 39 eyes, in which traditional pterygium operation was performed. The operation time, postoperative corneal epithelium healing time, patient comfort and recurrence rate between the two groups were compared. Results The conjunctival flap of patients in the two groups healed well. The operation time of the trial group and the control group were (23.06±1.87) minutes and (30.63 ± 2.43) minutes. The difference was statisially significant (t=5.46, P=0.000); The healing time of corneal epithelium were (2.13 ± 0.37) days in trial group and (2.87 ± 0.41) days in control group and the difference was statisially significant (t=4.91, P=0.002); The scores of postoperative discomfort were 0.89±0.39 in trial group and 2.43±0.74 in control group and the difference was statisially significant (t=3.13, P=0.025). The follow-up time was 6 months, and there was no recurrence being found. Conclusion Preoperative UBM examination of pterygium can effectively identify corneal infiltration and adhesion of pterygium, which is conductive to better removal of pterygium head. Key words: Pterygium; Ultrasound biomicroscopy; Stem cell transplantation

The application of ultrasound biomicroscopy on the early diagnosis of occult chestnut thorn foreign bodies in sclera

Objective To analyse the significance to the application of ultrasound biomicroscopy (UBM) in the early diagnosis of occult chestnut thorn foreign bodies in sclera. Methods Thirty-five eyes of 30 patients who were diagnosed as occult scleral chestnut thorn foreign bodies were retrospectively studied. UBM were used to diagnose suspicious scleral foreign bodies. Results Sixty foreign bodies were confirmed by UBM, 58 chestnut thorn foreign bodies were removed by surgical operation, and the false positive rate was 3.5%. One patient with negnative-UBM developed conjuctival redness, and one chestnut thorn foreign bodies was removed by surgical operation, and the false negative rate was 1.8%. Conclusion Ultrasound biomicroscopy is helpful to early detection of occult scleral chestnut thorn foreign bodies, confirming the quantity of chestnut thorns, and is conductive to the intraoperative localization. Key words: Foreign bodies, chestnut thorn, scleral, occult; Ultrasound biomicroscopy

Ultrasound biomicroscopy in the diagnosis of chestnut thorn in sclera

Objective To investigate the application of ultrasound biomicroscopy (UBM) in the diagnosis of sclera chestnuts thorns. Methods Retrospective study of 65 eyes of 65 cases which were diagnosed as scleral chestnuts thorns. Before operation, clinical examination was performed, including slit lamp microscopy and anterior segment photograph. Chestnuts thorns were localized using UBM were confirmed by surgical operation. Results Scleral chestnuts thorns of all cases were extracted successfully after being localized by UBM. Five eyes have local sclera erosion and thinning. Among which 1 eye get autologous sclera transplantation for its sclera was too thin.One eye was suffering from bacterial endophthalmitis after operation. His eye ball was saved after vitrectomy and lensectomy combined with postoperative antibiotic therapy. Conclusion UBM is highly significant and has great practical value for diagnosing chestnuts thorns in sclera. And UBM can find chestnuts thorns in time, alleviate introcular infection, decrease misdiagnosis and missed diagnosis. It makes up for the dificiency of routine clinical examination and imaging examination. Key words: Ultrasound biomicroscopy; Chestnuts thorns, sclera

Clinical application of ultrasound biomicroscopy in the treatment of congenital corneal opacities

Objective To investigate the clinical application of ultrasound biomicroscopy in the treatment of congenital corneal opacities.Methods Medical records of 20 eyes (15 patients) with congenital corneal opacity treated at our hospital from July 2004 to November 2011 were retrospectively reviewed.Best corrected visual acuity testing,intraocular pressure testing,slit-lamp anterior segment examination,fundus examination,slit-lamp microscopic photography,B scan examination,and ultrasound biomicroscopy were performed for analysis of complications of congenital corneal opacity and selection of surgical approaches.Results The ultrasound biomicroscopic examination showed that 5 eyes had no Descemet's membrane and corneal endothelium,20 eyes had anterior synechia,5 eyes had aniridia,3 eyes had loss of lens cortex,13 eyes had cataract,14 eyes had closed angle,and 3 eyes had pupillary membrane.14 of 20 eyes received surgical treatment,including penetrating keratoplasty combined with cataract extraction and trabeculectomy (5 eyes),penetrating keratoplasty combined with pupil angioplasty (3 eyes),penetrating keratoplasty combined with cataract extraction (3 eyes),penetrating keratoplasty combined with trabeculectomy (2 eyes),and lamellar keratoplasty (1 eye).Conclusions Ultrasound biomicroscopy is important to guide the diagnosis and treatment of congenital corneal opacity. Key words: Microscopy,acoustic; Corneal opacity

Application of ultrasound biomicro-scopy in the planning of cataract surgery in anterior megalophthalmos

Anterior megalophthalmos, a rare hereditary disorder, is macrocornea (horizontal corneal diameter more than 13 mm) in association with enlarged lens-iris diaphragm and ciliary ring. One of the major challenging issues in the cataract surgery of these patients is preventing intraocular lens (IOL) malposition, because of probable large capsular bag. Several approaches have been selected by previous surgeons, such as, custom-made anterior chamber IOLs. In this study, we show a normal capsular bag diameter despite ciliary ring enlargement, with application of ultrasound biomicroscopy (UMB). We suggest that in cases of anterior megalophthalmos without phacodonesis, UBM could measure the actual size of the capsular bag and obviate the need for further procedures.

Application of ultrasound biomicroscopy in open-globe injury

Background Open-globe injury of zone Ⅱ is a severe eyeball wound in the sclera area near 5mm from the corneal limbus.To accurately evaluate the local tissue structure after the wounding is very important for lessening the complications of eye injury.Ultrasound biomicroscope (UBM) has been proven useful in examining eyeball wall and vitreous at the wound in order to offer the useful information about whether secondary operation is needed for the injured eyes and when is the optimal timing for surgery.Objective The present study is to explore the clinical application of UBM in open-globe injury of zone Ⅱ. Methods This is an observational study of clinical cases.UBM examination was performed on 38 eyes of 38 cases received emergency repair surgery of open-scleral injury.The restore status of sclera,ciliary body and vitreous of injuried zone (zone Ⅱ) were evaluated under the UBM in 3-5 days after the operation.The comprehensive results of UBM,B-scan and ophthalmoscope examinations were analyzed to determine the further treatment.The oral informed consent was obtained from each subject before this trial.Results Vitreous surgery were performed on 15 cases,and all wounds were found by UBM and were proven in the surgery.The other 23 cases were followed up in out-patient department and no obvious complications were found.Conclusion UBM is a valuable and atraumatic examination for open-globe injury of zone Ⅱ.It offers important and appraisal information about ocular injury. Key words: UBM; ocular injury; ophthalmic examination

Application of Ultrasound Biomicroscopy in Dog's Iridocorneal Angle

Application of Ultrasound Biomicroscopy in Dog's Iridocorneal Angle