INTRODUCTION: The risks to the fetus-infant increase substantively in high risk pregnancies. The efforts are always to ensure a vaginal rather than a caesarian delivery. The present study aims to assess the safety and efficacy of Prostaglandin E2( PGE2) intracervical gel and oral PGE2 in inducing and augmenting labour in such patients. METHODS: PGE2 intracervical gel was used for induction oflabour in 100 high risk pregnancies. PGE2 gel was supplemented by oral PGE2 afterARM. RESULTS: PGE2 successfully induced labour in 60% of women while it improved the Bishop's score in the rest of the cases. L.S.C.S. was needed in only 7% of women. CONCLUSION: Intracervical PGE2 gel application is a safe and efficacious method of inducing labour, which can be augmented with oral PGE2 when needed. DOI: http://dx.doi.org/10.3126/jucms.v1i4.9568 Journal of Universal College of Medical Sciences (2013) Vol.1 No.04: 22-25
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