Application Of Methyl Nicotinate Research Articles

Protective and anti-inflammatory effects of a dermocosmetic formulation containing a combination of vitamins

The exposome accelerates the skin aging process, highlighting the need to use cosmetics capable of repairing the damage and maintaining the skin's physiological conditions. Thus, the present study aims to evaluate the potential anti-inflammatory and protective action of a dermocosmetic formulation combination of vitamins. For this, a gel-cream formulation added or not with 3% of ascorbyl tetraisopalmitate and 1% of D-panthenol was developed. The stability and sensory properties of these formulations were evaluated. In addition, a short-term clinical efficacy study of the formulations was carried out for 7 days. After this period, measurements were taken in terms of transepidermal water loss and blood microcirculation by Laser Doppler at the initial time and after the application of methyl nicotinate. The results showed that the formulations remained stable during the study period and showed pseudoplastic non-Newtonian behavior. In addition, the association of vitamins was effective in the protection of the skin against the effects of methyl nicotinate by reducing blood microcirculation, which suggests that the active substances in combination can have an anti-inflammatory and protective action on the skin barrier function.

Image-based skin color and texture analysis/synthesis by extracting hemoglobin and melanin information in the skin

This paper proposes an E-cosmetic function for digital images based on physics and physiologically-based image processing. A practical skin color and texture analysis/synthesis technique is introduced for this E-cosmetic function. Shading on the face is removed by a simple color vector analysis in the optical density domain as an inverse lighting technique. The image without shading is analyzed by a previously introduced technique that extracts hemoglobin and melanin components by independent component analysis. Experimental results using UV-B irradiation and the application of methyl nicotinate on the arms support the physiological validity of the analysis and the effectiveness of the proposed shading removal. We synthesized the way facial images changed due to tanning or alcohol consumption, and compared the synthesized images with images of actual changes in skin color. The comparison shows an excellent match between the synthesized and actual images of changes due to tanning and alcohol consumption. We also proposed a technique to synthesize the change of texture in pigment due to aging or the application of cosmetics. The pyramid-based texture analysis/synthesis technique was used for the spatial processing of texture. Using the proposed technique, we could realistically change the skin color and texture of a 50 year-old woman to that of a 20 year-old woman.