Application Of Test Research Articles

PFAS Porewater concentrations in unsaturated soil: Field and laboratory comparisons inform on PFAS accumulation at air-water interfaces

Poly- and perfluoroalkyl substance (PFAS) leaching from unsaturated soils impacted with aqueous film-forming foams (AFFFs) is an environmental challenge that remains difficult to measure and predict. Complicating measurements and predictions of this process is a lack of understanding between the PFAS concentrations measured in a collected environmental unsaturated soil sample, and the PFAS concentrations measured in the corresponding porewater using field-deployed lysimeters. The applicability of bench-scale batch testing to assess this relationship also remains uncertain. In this study, field-deployed porous cup suction lysimeters were used to measure PFAS porewater concentrations in unsaturated soils at 5 AFFF-impacted sites. Field-measured PFAS porewater concentrations were compared to those measured in porewater extracted in the laboratory from collected unsaturated soil cores, and from PFAS concentrations measured in the laboratory using batch soil slurries. Results showed that, despite several years since the last AFFF release at most of the test sites, precursors were abundant in 3 out of the 5 sites. Comparison of field lysimeter results to laboratory testing suggested that the local equilibrium assumption was valid for at least 3 of the sites and conditions of this study. Surprisingly, PFAS accumulation at the air-water interface was orders of magnitude less than expected at two of the test sites, suggesting potential gaps in the understanding of PFAS accumulation at the air-water interface at AFFF-impacted sites. Finally, results herein suggest that bench-scale testing on unsaturated soils can in some cases be used to inform on PFAS in situ porewater concentrations.

Application of ANN, hypothesis testing and statistics to the adsorptive removal of toxic dye by nanocomposite

Statistics can be used in a variety of ways to present, compute, and critically analyze experimental data. To determine the significance and validity of the experimental data, a variety of statistical tests are used. Using a synthesized CoO/NiO/MnO2 Nanocomposite, the present study used adsorption to remove the dye Bromophenol Blue (BPB) from a contaminated aqueous solution. In order to (a) determine the optimal pH of the solution, (b) confirm the experiment's success, and (c) investigate the effect of adsorbent dose on BPB dye removal from aqueous solutions. The experimental data were statistically analyzed through hypothesis testing using the t-test, paired t-test, and Chi-square test. The null hypothesis that the optimal pH value is 7 is accepted since tobserved (−1.979)<ttabulated (−2.262). Since χ2observed (1.052)< χ2tabulated (3.841), null hypothesis that the higher adsorbent dose helps in higher % removal of dye is accepted. Both the obtained Freundlich adsorption isotherm and the Langmuir isotherm's R2 values, which were both close to 1, indicate that the isotherms are favorable. Karl Pearson's relationship coefficient values for Langmuir and Freundlich adsorption isotherms found to be 0.9693 and 0.9994 respectively, which show a more significant level of connection between's the factors. The ANN model predicted adsorption percentage with regression value R is 0.996. ANN model result predict 99.60 % BPB dye adsorption using optimized parametric conditions. The ANN model produced values that were more precise, reliable, and reproducible, demonstrating its superiority.

Application of Oxygen Saturation Test after Replantation of Avulsed Immature Permanent Teeth: A Prospective Observational Study

IntroductionThe evaluation of pulp status is crucial for avulsed immature permanent teeth after replantation. In addition to commonly used clinical and radiographic examinations providing clinical evidence, the oxygen saturation test may offer valuable assistance. The aim of this study was to analyze the efficacy of a pulse oximeter in evaluating pulp status in avulsed and replanted immature permanent teeth. MethodsA prospective observational study was performed including 51 avulsed and replanted immature permanent teeth. Routine clinical and radiographic examinations were performed and used as the basis for the diagnosis of pulp status during the 1-year follow-up period. Meanwhile, the oxygen saturation values of these teeth were recorded using a modified pulse oximeter at each visit. ResultsSeven teeth completed pulp revascularization (success group), whereas 44 teeth failed to revascularize (failure group). Abnormal clinical and/or radiographic manifestations in the failure group were observed at an average period of 42.7 days, which was too late because a high incidence of inflammatory root resorption (43.18%) had occurred. For oxygen saturation tests, teeth in the success group showed an immediate postreplantation oxygen value of 70.71 ± 3.35, then an upward trend starting from the 2-week postreplantation visit, and a significantly increased final value of 81.86 ± 2.34 at the 1-year visit. In contrast, no increase trend was found for teeth in the failure group because abnormal clinical and/or radiographic manifestations emerged. ConclusionsThe oxygen saturation test is a reliable diagnostic method to evaluate pulp status of avulsed teeth as early as 2 weeks after replantation.

Interference; Quality of Law; Triple Test; Proportionality. Theoretical and Practical Aspects and Applicability

This article aims to bring clarity, based on the case law of the European Court of Human Rights, concerning the applicability of the triple test in cases of interferences admitted by national authorities in the human rights and fundamental freedoms of the citizens in their jurisdiction. In essence, the institution of the triple test, as mentioned in the judgments of the Strasbourg Court, is nothing more than a proportionality test that explains the admissible elements of such interferences and that must prove that a restriction of the exercise of a right has to be provided in the domestic law, to pursue one or more legitimate aims, as well as to be proportionate to the aims pursued and, therefore, necessary in a democratic society.

Current perspectives on the use of artificial intelligence in critical patient safety

Intensive Care Units (ICUs) have undergone enhancements in patient safety, and artificial intelligence (AI) emerges as a disruptive technology offering novel opportunities. While the published evidence is limited and presents methodological issues, certain areas show promise, such as decision support systems, detection of adverse events, and prescription error identification. The application of AI in safety may pursue predictive or diagnostic objectives. Implementing AI-based systems necessitates procedures to ensure secure assistance, addressing challenges including trust in such systems, biases, data quality, scalability, and ethical and confidentiality considerations.The development and application of AI demand thorough testing, encompassing retrospective data assessments, real-time validation with prospective cohorts, and efficacy demonstration in clinical trials. Algorithmic transparency and explainability are essential, with active involvement of clinical professionals being crucial in the implementation process.

On repeated diagnostic testing in screening for a medical condition: How often should the diagnostic test be repeated?

In screening large populations a diagnostic test is frequently used repeatedly. An example is screening for bowel cancer using the fecal occult blood test (FOBT) on several occasions such as at 3 or 6 days. The question that is addressed here is how often should we repeat a diagnostic test when screening for a specific medical condition. Sensitivity is often used as a performance measure of a diagnostic test and is considered here for the individual application of the diagnostic test as well as for the overall screening procedure. The latter can involve an increasingly large number of repeated applications, but how many are sufficient? We demonstrate the issues involved in answering this question using real data on bowel cancer at St Vincents Hospital in Sydney. As data are only available for those testing positive at least once, an appropriate modeling technique is developed on the basis of the zero-truncated binomial distribution which allows for population heterogeneity. The latter is modeled using discrete nonparametric maximum likelihood. If we wish to achieve an overall sensitivity of 90%, the FOBT should be repeated for 2 weeks instead of the 1 week that was used at the time of the survey. A simulation study also shows consistency in the sense that bias and standard deviation for the estimated sensitivity decrease with an increasing number of repeated occasions as well as with increasing samplesize.

Simple, sensitive, and visual detection of 12 respiratory pathogens with one-pot-RPA-CRISPR/Cas12a assay.

Respiratory infections pose a serious threat to global public health, underscoring the urgent need for rapid, accurate, and large-scale diagnostic tools. In recent years, the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system, combined with isothermal amplification methods, has seen widespread application in nucleic acid testing (NAT). However, achieving a single-tube reaction system containing all necessary components is challenging due to the competitive effects between recombinase polymerase amplification (RPA) and CRISPR/Cas reagents. Furthermore, to enable precision medicine, distinguishing between bacterial and viral infections is essential. Here, we have developed a novel NAT method, termed one-pot-RPA-CRISPR/Cas12a, which combines RPA with CRISPR molecular diagnostic technology, enabling simultaneous detection of 12 common respiratory pathogens, including sixbacteria and sixviruses. RPA and CRISPR/Cas12a reactions are separated by paraffin, providing an independent platform for RPA reactions to generate sufficient target products before being mixed with the CRISPR/Cas12a system. Results can be visually observed under LED blue light. The sensitivity of the one-pot-RPA-CRISPR/Cas12a method is 2.5 × 100copies/μL plasmids, with no cross-reaction with other bacteria or viruses. Additionally, the clinical utility was evaluated by testing clinical isolates of bacteria and virus throat swab samples, demonstrating favorable performance. Thus, our one-pot-RPA-CRISPR/Cas12a method shows immense potential for accurate and large-scale detection of 12 common respiratory pathogens in point-of-care testing.

Determining V̇O2max in competitive swimmers: Comparing the validity and reliability of cycling, arm cranking, ergometer swimming, and tethered swimming

ObjectivesThis study aims to identify the optimal method for determining V̇O2max in competitive swimmers in terms of validity and test–retest reliability. DesignControlled experiment. MethodsTwenty competitive swimmers performed four maximal incremental exercise tests: cycling, arm cranking, ergometer swimming, and tethered swimming. Gas analysis was conducted to estimate V̇O2max. Validity was assessed in terms of the amount of variance of the performance on a 1500-m time trial explained by the estimated V̇O2max . Test–retest reliability was evaluated using the intraclass correlation coefficient (ICC). ResultsV̇O2max obtained from tethered swimming, ergometer swimming, and cycling explained a similar amount of variance of the 1500-m performance (R2 = 0.64, 0.64 and 0.65, respectively). However, ergometer swimming yielded significantly lower V̇O2max estimates (40.54 ± 6.55 ml/kg/min) than tethered swimming (54.40 ± 6.21 ml/kg/min) and cycling (54.39 ± 5.63 ml/kg/min). Arm cranking resulted in both a lower explained variance (R2 = 0.41) and a significantly lower V̇O2max (43.14 ± 7.81 ml/kg/min). Tethered swimming showed good reliability (ICC = 0.81). ConclusionsBicycle and tethered swimming tests demonstrated high validity with comparable V̇O2max estimates, explaining a large proportion of differences in endurance performance. Choosing between these two methods involves a trade-off between a higher practical applicability and reliability of the bicycle test and the more sport-specific nature of the tethered swimming test.

A Randomised Active Controlled Clinical Trial to Evaluate the Efficacy of Vyoshadi Yoga versus Simethicone drop in Udarshula (Infantile Colic)

Background: Infantile colic is said to be the most common complaint among few weeks to 6 months of age babies and is characterised by continual sobbing. Acharya Kashyapa has portrayed a disease named ‘Udarshula,’ which shows the same clinical features as ‘Infantile colic. The present study aimed to evaluate the efficacy of ‘Vyoshadi Yoga in Udarshula. Material and Methods- This study belongs to Randomized Active controlled clinical trial which comprises total 40 patients of Udarshula randomly divided into two equal groups. Group A (Trial group) was treated with Vyoshadi Yoga two times a day after feeding with Honey and Group B (Control group) was treated with Simethicone drop administered two times a day after feeding for 14 days. Assessment of Udarshula was done by using the parameters of the FLACC scale, Subjective Criteria and Parent Questionnaire on 0,3rd ,7th, and 14th day. Results- Positive results were seen in both groups. After application of Wilcoxon Sign Rank test, it has been observed that both the formulation of Vyoshadi Yoga and Simethicone were found to be equally significant P-value=0.01&lt;0.05 in both groups. On the 28th day, post follow-up showed both the group were reduced the symptoms of Infantile colic and improvement was seen. Conclusion- Significant results were noted in both the interventions. No ADR was reported. Further large sample studies with standard control would render better evidence in results with justification.

Evaluating the Knowledge, Practice, and Regulatory Situation of Veterinary Experts Regarding Counterfeit Veterinary Medications in the Selected Districts of Central Gondar Zone, Ethiopia.

The intentional and illegal misrepresentation of fake medications involves falsely indicating their source. These fraudulent medications can include products that contain either accurate or incorrect ingredients, lack proper labeling, have insufficient quantities of ingredients, and are packaged with counterfeit packaging. This unlawful activity has led to treatment failures, the development of antibiotic resistance, adverse effects, and even deaths. Hence, the objective of this study was to assess the knowledge, practice, and regulatory status of veterinary drug experts in the central Gondar zone of Ethiopia regarding counterfeit veterinary medications. From January 2023 to July 2023, a self-administered structured questionnaire was utilized to conduct a cross-sectional study in Central Gondar Zone, Ethiopia. The analysis of the data involved the application of descriptive and chi-square tests. The study revealed that the majority of professionals possessed a work experience ranging from 5 to 9 years (23; 56.1%). Additionally, a total of 25 individuals (61.0%) who participated in the research had not undergone any kind of training. It was observed that a significant proportion of participants (82.9%) possessed knowledge about counterfeit veterinary drugs. Only about 63% and 36% of respondents had high knowledge and good practice concerning veterinary counterfeit drugs, respectively. Only 29.3% of participants have reported practices. Furthermore, a poor regulatory level of coordination was detected (85.4%). The study revealed a significant (χ2 =7.6165; p = 0.022) disparity between the respondents' practice levels and training. Respondents' regulatory levels were also significantly associated (p < 0.05) with their sex (χ2 = 13.34; p = 0.001) and work experience (χ2 = 13.64; p = 0.033). The research findings also revealed a noteworthy correlation between practice and regulatory activity (χ2 = 15.0463; p = 0.005). The study outlines the necessity of awareness initiatives, with a focus on the significance of veterinary experts' knowledge, practice, and regulatory efforts in addressing the issue of counterfeit veterinary medications.

Application of a clamshell isothermal nucleic acid amplification analyzer in the detection of lower respiratory tract bacteria

ObjectivesThe clamshell isothermal nucleic acid amplification analyzer RTisochip-S, a next-generation instrument featuring improved structural design, enhanced functional integration, reduced cost, and increased portability, was assessed for its suitability in clinical respiratory pathogens detection. MethodsThe certificated detection kit for lower respiratory tract bacteria (LRTB-kit) was applied to evaluate the performance of RTisochip-S via sensitivity, specificity, and repeatability analysis. The clinical specimens, including 51 sputum specimens and 10 bronchoalveolar lavage fluid specimens, were simultaneously detected on both RTisochip-S and a certificated reference instrument (RTisochip-A) to assess the consistency. ResultsThe results indicated that RTisochip-S fulfills the sensitivity, specificity, and repeatability requirements of the LRTB-Kit, and the results of clinical specimens on the two instruments were consistent. ConclusionsRTisochip-S is satisfying the clinical detection of respiratory pathogens while enhancing portability and compactness, making it more well-suited for point-of-care testing (POCT) applications.

Detection and delineation of cracks and voids in concrete structures using the ground penetrating radar technique

The accurate detection of early-age cracking and voids in concrete structures is vital for assessing their health and preventing deterioration, ultimately saving lives and resources. While Ground Penetrating Radar (GPR) offers a widely used method for concrete inspection and defect detection, its accuracy is subject to various limitations influenced by factors such as software, defect dimensions, moisture, and the analysis and interpretation of data. This study presents comprehensive techniques for detecting, delineating, and analyzing hidden cracks and voids in concrete using GPR, validated through laboratory testing and real-world applications. Introducing “DefectInspectoPy,” Python software, aims to address limitations in traditional GPR data processing software and defect detection methods. Results demonstrate the effectiveness of the proposed methods in accurately locating, analyzing, and delineating defects, aiding in determining coring locations for concrete structures. These findings have significant implications for enhancing safety, reducing maintenance costs, and preserving concrete infrastructure integrity.

Impact of smartphone on mental health among medical undergraduates: A cross-sectional study

BACKGROUND: Smartphones have become an indispensable part of almost everyone’s life. India has now become the leading and second-largest Smartphone market in the world. It has been noted that the purpose of Smartphone usage has exceptionally changed over the past few years, especially among students, professionals, and the common man. Smartphones have now become essential and the need of the hour, and medical students are no exception. Smartphones can make “smart students smarter”! There are now 10,275 unique applications labeled under the “Medical” and “Healthcare and Fitness” categories. The common medical applications used are MedCalc, Drug Infusion, Flashcards, Encyclopedia, Merck Manual, Medscape, PubMed, Epocrates, MedlinePlus, Lab test applications, Medical Dictionary, Eponyms etc. Despite the advantages and needs of smartphones, they have proven to be a source of potential hazard to human health, not only physical but also mental, social, and emotional well-being. There is consistent evidence for co-morbidity (such as obesity, heart diseases, neck and back pain, etc.) between excessive smartphone use and other psychiatric disorders, such as depression, anxiety, obsessive and compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD) similar to internet addiction. The significant association of this addiction with poorer sleep quality and higher perceived stress has been a cause for concern. Hence, further investigation to explore the association between smartphone addiction and mental health, this study was undertaken. MATERIALS AND METHODS: Our study was undertaken in Dr VMGMC, Solapur, from June to August 2022, after obtaining approval from the ethical committee, approval number 172/22. Total voluntary participation for the study was 600 (from first to final year), and accordingly convenient sample size was taken. RESULTS: We found that out of the total participants, 42% of the participants had an average screen time of 4–6 h daily. A very small percentage of participants (4%) spent less than two hours in front of a screen. Alarmingly, 65% of the participants had an average screen time of more than 4 hours, which puts them at risk for the negative health impacts of prolonged screen time. Around 12% of them had symptoms of mild stress, 10.3% for mild anxiety, and 15.6% for mild depression. 10.6% had symptoms of moderate stress, 23.3% for moderate anxiety, and 16% for moderate depression. A small proportion of undergraduates, that is, 5%, 16%, and 11.6%, had symptoms of severe and extremely severe stress, anxiety, and depression, respectively. CONCLUSION: The study participants did not feel a lot of stress, anxiety, or depression symptoms when smartphones were used judiciously and mostly for non-social purposes (such as studying, listening to music, or watching videos). This investigation led us to the conclusion that there are some positive effects of smartphones on mental health. However, those who spent an excessive amount of time on their smartphones for social contact, with an average screen time of 5 h, showed signs of mild to moderate sadness, moderate anxiety, and tension, demonstrating that social media had a negative impact on the mental health of medical undergraduates. Therefore, efforts should be made to inform medical students about how using a smartphone is harming their mental health.

Utilizing the open-source programming language Python to create interactive Quality Assurance dashboards for diagnostic and screening performance in Cytology

Effective feedback on cytology performance relies on navigating complex laboratory information system data, which is prone to errors and lacks flexibility. As a comprehensive solution, we used the Python programming language to create a dashboard application for screening and diagnostic quality metrics. Data from the 5-year period (2018-2022) were accessed. Versatile open-source Python libraries (user developed program code packages) were used from the first step of LIS data cleaning through the creation of the application. To evaluate performance, we selected 3 gynecologic metrics: the ASC/LSIL ratio, the ASC-US/ASC-H ratio, and the proportion of cytologic abnormalities in comparison to the total number of cases (abnormal rate). We also evaluated the referral rate of cytologists/cytotechnologists (CTs) and the ratio of thyroid AUS interpretations by cytopathologists (CPs). These were formed into colored graphs that showcase individual results in established, color-coded laboratory "goal," "borderline," and "attention" zones based on published reference benchmarks. A representation of the results distribution for the entire laboratory was also developed. We successfully created a web-based test application that presents interactive dashboards with different interfaces for the CT, CP, and laboratory management (https://drkvcsstvn-dashboards.hf.space/app). The user can choose to view the desired quality metric, year, and the anonymized CT or CP, with an additional automatically generated written report of results. Python programming proved to be an effective toolkit to ensure high-level data processing in a modular and reproducible way to create a personalized, laboratory specific cytology dashboard.

Flowback Rates for Pump-In/Flowback Test

Summary The pump-in/flowback test (PIFT), often referred to as the diagnostic fracture injection test (DFIT) with flowback, offers notable advantages in terms of time efficiency and accuracy, particularly in the context of low-permeability formations. The key to the success of this test lies in the careful selection of an optimal flowback rate to yield meaningful results. The fundamental assumption underlying the pressure analysis of these tests is the uniform closure of fractures during the flowback phase, which is considered the default fracture closure mode in current analyses. In this study, we present evidence that challenges the validity of this assumption, highlighting instances where unsuitable flowback rates can lead to nonuniform fracture closure and result in abnormal pressure data. To address this challenge, we identify different closure modes through the signature of fracture closure in the excessive bottomhole pressure decline curve. Subsequently, we propose an optimal range of flowback rates using a scaling analysis approach to obtain a uniform closure mode in an extended openhole section of a vertical well. Our method has been rigorously validated through 3D numerical simulations and field studies, enhancing its reliability and applicability. This approach helps operators to conduct effective tests in complex situations, overcoming a barrier to widespread test application.

PCB Rogowski Coil With DC Sensing for Double Pulse Test Applications

PCB Rogowski Coil With DC Sensing for Double Pulse Test Applications

Damage assessment in L-shaped bends by nonlinear feature guided waves

L-shaped bends are crucial lightweight structural components in aerospace manufacturing, renowned for their high specific strength and stiffness. However, the geometric configuration of these bends makes them susceptible to stress concentration in the bending zone. Effective technique for damage assessment of the bending region of L-shaped bends is highly demanded. This paper proposes a nondestructive testing method using nonlinear ultrasonic feature guided waves (FGWs) for early damage assessment of L-shaped bends. Semi-analytical finite element (SAFE) method and perfectly matched layer (PML) technique are employed to analyze FGW propagation in L-shaped bends. Three-dimensional finite element models are utilized to investigate the FGWs propagation in the bending region of L-shaped bends in a numerical perspective. Cumulative second harmonic generation (SHG) of FGWs is successfully observed by selecting suitable mode pairs based on synchronism and non-zero power flux conditions, which provides a promising alternative for early damage assessment in L-shaped bends. Experimental findings are consistent with the numerical ones. Subsequently, thermal damage and plastic deformation with varying gradients were introduced into the bending region of L-shaped bends. The use of SHG of selected FGW mode has effectively assessed the damage with an improved sensitivity, compared to conventional linear acoustic one. This investigation substantiates the potential of nonlinear FGWs in detecting early damage in L-shaped bends, offering promise for future industrial testing applications.

Genetic Association of MSTN Gene Variant (18:66493737T&gt;C) with Track Performance &amp; Muscle Development in Pakistani Horses

The horse, revered for its diverse traits including racing prowess, gaitedness, and distinctive behavior, plays a pivotal role in various sports. Numerous studies have linked racing performance in horses to the MSTN gene across global populations. Objectives: To investigate the genetic variability of the 18:66493737T&gt;C variant in Pakistani random-bred horses. Methods: ARMS-PCR was employed where 24 horses sourced from UVAS equine clinic were genotyped. Results: Revealing a population distribution of 54% homozygous wild-type (TT), 41% heterozygous (TC), and 4% homozygous mutant (CC) at this locus. The alternative allele frequency within elite performers and control horses stood at 0.36 and 0.12, respectively. Application of the Chi-Square association test using the PLINK data toolset yielded a highly significant p-value of 7.832×10-6. Conclusions: This underscores significant genetic variability at the locus in the Pakistani horse population, aligning with global patterns. Future studies are advocated, incorporating racing performance data and encompassing diverse indigenous horse breeds with substantial sample sizes. Identification of subject markers can inform targeted breeding strategies, contributing to the enhancement and preservation of desirable traits across various horse breeds

Advancements and Applications of Preimplantation Genetic Testing in In Vitro Fertilization: A Comprehensive Review.

Preimplantation genetic testing (PGT) has become an integral component of assisted reproductive technology (ART), offering couples the opportunity to screen embryos for genetic abnormalities before implantation during in vitro fertilization (IVF). This comprehensive review explores the advancements and applications of PGT in IVF, covering its various types, technological developments, clinical applications, efficacy, challenges, regulatory aspects, and future directions. The evolution of PGT techniques, including next-generation sequencing (NGS) and comparative genomic hybridization (CGH), has significantly enhanced the accuracy and reliability of genetic testing in embryos. PGT holds profound implications for the future of ART by improving IVF success rates, reducing the incidence of genetic disorders, and mitigating the emotional and financial burdens associated with failed pregnancies and genetic diseases. Recommendations for clinicians, researchers, and policymakers include staying updated on the latest PGT techniques and guidelines, exploring innovative technologies, establishing clear regulatory frameworks, and fostering collaboration to maximize the potential benefits of PGT in assisted reproduction. Overall, this review provides valuable insights into the current state of PGT and its implications for the field of reproductive medicine.

Qualitative Fecal Immunochemical Test as a Screening Test for Colorectal Cancer

Colorectal cancer is one of the most common cancers, causing mortality, morbidity, and economic burden. Patient survival differs due to differences in access to health facilities, as well as diagnostic and therapeutic modalities. Early detection can allow colorectal cancer to be diagnosed at an earlier stage, improving patient outcomes and lowering mortality. Due to the lack of a national screening program in Indonesia, as well as the uneven availability of colonoscopy tools, the fecal immunochemical test has become the preferred screening method. This cross-sectional study aims to validate the application of the fecal immunochemical test for colorectal cancer detection. Fecal immunochemical test examination is performed on all patients with suspected colorectal cancer who will undergo a colonoscopy examination at Prof. Hospital dr. I.G.N.G. Ngoerah, Bali, Indonesia. Histopathological examination is used to diagnose colorectal cancer. This study included 78 people with a colorectal cancer prevalence of 40.91%. There were 38(57.6%) subjects with positive fecal immunochemical test results in this study, and 25(65.6%) of them were diagnosed with colorectal cancer. The sensitivity, specificity, positive predictive value, and negative predictive value of the qualitative fecal immunochemical test in detecting colorectal cancer were 92.59%, 66.67%, 65.79%, and 92.86%, respectively. The qualitative fecal immunochemical test has high sensitivity and can be used as an objective and accurate method of screening symptomatic patients with suspected CRC for colonoscopy.