Obesity is a public health problem, with alarming numbers, when viewed as incidence projections for the coming years. It is a metabolic syndrome characterized by excess fat in adipose tissue. In view of this, see Search for obesity. The practice of daily intake of apple cider vinegar with therapeutic treatment has been widespread, due to the potential antihyperlipidemic property of acetic acid. This study aimed to evaluate the effect of using apple cider vinegar on the surveillance of the high calorie diet. 32 male Wisteros were used, divided into 4 groups: Control Group (C), Group with administration of apple cider vinegar (V), Group with administration of high calorie diet (D), Group with administration of high calorie diet associated with administration of apple cider vinegar (DV). During the experiment, the groups that had induced obesity received a diet in the cafeteria, while other groups received ration. After 3 months, apple cider vinegar was made for 8 weeks. The animals were sacrificed and taken from blood, mesenteric fat, aorta and liver samples for analysis. There are no significant differences due to the use of vinegar, except for TGO and TGP in groups C and V. Therefore, apple cider vinegar is not effective in reducing levels of total cholesterol, HDL, VLDL, LDL, triglycerides, blood glucose, TGO and TGP when already tall, nor for weight reduction of animals. However, it was shown to be hepatoprotective, when associated with a normolipidic diet.