An apodized Chirped Fiber Bragg Grating (CFBG) is presented to compute and depict the sensing response for various uniform and non-uniform profiles of the temperature and the strain for different chirp parameters. The effectiveness of the CFBG can be reduced owing to the appearance of wide-scale side lobes as well as increasing group delay ripples (GDR). The introduction of apodization profile is highly impactful to enhance the sensing efficiency by minimizing the side lobes level along with the quantity of GDR. The sensing response of the apodized CFBG with different chirp parameters are evaluated for various ranges of uniform temperature (30 °C–80 °C) and strain (300 µ∊–550 µ∊). Furthermore, different non-uniform Gaussian profiles are also introduced to illustrate the overview for detecting and locating the spot size sources of measurands. This approach is highly desirable for estimating the structural integrity by ensuring the safety, efficiency, and reliability of the CFBG-based sensing outcomes.