A 50-W-class annular Hall thruster is studied with a hybrid axial–radial two-dimensional model. Ions are described by a kinetic approach, whereas fluid conservation equations are solved for electrons. In such models, additional (anomalous) contributions must be added to the momentum-transfer electron collision frequency to obtain realistic values of the cross-field electron mobility. First, a parametric study is performed, where anomalous transport is described with a simple two-region model based on constant empirical parameters. The simulated global performance is subsequently compared with experimental measurements. Then, laser-induced fluorescence ion velocity measurements are employed to infer a continuous profile of the anomalous electron collision frequency along the channel centerline. The model reproduces the performance, the acceleration structure, the current oscillations, and the doubly charged ion fraction of the laboratory thruster. Measurements of the ion velocity distribution function highlight the presence of a slow ion population in the near plume. The production of the slow ions and their growth for increasing distances from the thruster channel exit is qualitatively reproduced by the model. The results obtained suggest that the generation and dynamics of the observed slow ions can be attributed to the presence of energetic electrons in the plume.