Animal Categories Research Articles

Using data from cue presentations results in grossly overestimating semantic BCI performance.

Neuroimaging studies have reported the possibility of semantic neural decoding to identify specific semantic concepts from neural activity. This offers promise for brain-computer interfaces (BCIs) for communication. However, translating these findings into a BCI paradigm has proven challenging. Existing EEG-based semantic decoding studies often rely on neural activity recorded when a cue is present, raising concerns about decoding reliability. To address this, we investigate the effects of cue presentation on EEG-based semantic decoding. In an experiment with a clear separation between cue presentation and mental task periods, we attempt to differentiate between semantic categories of animals and tools in four mental tasks. By using state-of-the-art decoding analyses, we demonstrate significant mean classification accuracies up to 71.3% during cue presentation but not during mental tasks, even with adapted analyses from previous studies. These findings highlight a potential issue when using neural activity recorded during cue presentation periods for semantic decoding. Additionally, our results show that semantic decoding without external cues may be more challenging than current state-of-the-art research suggests. By bringing attention to these issues, we aim to stimulate discussion and drive advancements in the field toward more effective semantic BCI applications.

Soil Mediated Helminthiasis: A Study on Neglected Tropical Disease in Wild Animals in Haryana

Background: Soil mediated/ transmitted helminthiasis (STH/SMH) is a neglected tropical disease and includes Ascarids, Trichuris and Hookworms, which prominently affects population living either in the low sanitary condition or in close proximity with the animals. Recent years have witnessed elevation in the Trichuris infection, with India ranking first globally. Variety of factors including low sanitation, close contact with animals, increased man and wild conflict contribute towards STH. However, co-relation of STH/SMH infection from wildlife have not been studied. Methods: The study was conducted for a period of 1 year from August, 2021 to September, 2022. Trichuris infection was present in 72 out of 131 carcasses of wild animals with prevalence rate of 35%. The prevalence percentage of Trichuris infection in different sub categories of wild animals was calculated. Seasonal prevalence rate was calculated with increased cases reported in summer season followed by monsoon. Additionally, fecal samples, worms and intestinal samples for further studies were collected. Result: Wild animals act as bridge for transmission of various zoonotic diseases. However, zoonotic potential of parasitic diseases are neglected in wild animals with no systematic literature. Based on our study we illustrate that wild animals hold considerate potential plausibly demonstrating an iceberg phenomenon. Wildlife is an essential component in the epidemiology of many, if not most, zoonoses, wildlife should be taken into account in the risk analysis framework.

මාතර හෙළ වෙදකම පිළිබඳ විමර්ශනාත්මක අධ්‍යයනයක්

Hela wedakama is Sri Lanka’s local helth insurance system. That has existed since time immemorial.This was not introduced from any other country, but was produced by the ancient inhabitants of ourcountry. Traditional Hela medicine treats the three categories of human, animal and non-humanTraditional medicine helps in the prevention of physical, mental, infectious and non-infectious diseases.The specialties of Hela medicine are unique to each region and they differ from each other. Matararegion has been known as the birth place of Hela medicine since time immemorial. Matara Helavedakama is at the forefront in providing treatment for human and non-human categories as well asphysical, mental, infectious and non-infectious diseases. Matara Hela medicine is special, because it isbased on the practices of the area for disease prevention. Accordingly, the content and practices ofMatara Hela medicine were studied in this research. Data was collected through library reference, fieldstudy and interviews. According to the facts revealed in the study, it was possible to identify thepeculiarities of Hela medicine, that is unique to the Matara area.

Impact of Pre-trained Weights on MobileNet Architectures for Animal Classification

This study aims to address the problem of improving animal image classification accuracy using different versions of MobileNet. Accurate animal classification plays a vital role in biodiversity protection, environmental monitoring, and agriculture. The research is significant because existing studies focus on specific models and datasets, leaving a gap in the comparative performance analysis of MobileNet versions. To address this issue, MobileNet V1, V2, and V3 models were utilized, both with and without ImageNet pre-trained weights. The models were trained on a dataset composed of 30,179 images from two sources, covering 13 animal categories. The experiment involved training the models over 10 epochs using a standard configuration of the TensorFlow framework, with accuracy serving as the primary evaluation metric.The results showed that MobileNet V3Large, with pre-trained weights, achieved the highest accuracy (97.43%), outperforming V1 and V2. Using pre-trained weights consistently enhanced performance, as models without pre-training exhibited lower accuracy and slower convergence. This study contributes by providing a comprehensive comparison of MobileNet versions in animal classification tasks, demonstrating the importance of pre-training and model architecture optimization for achieving high accuracy in image classification.

How Cultural Input Shapes the Development of Idealized Biological Prototypes

ABSTRACT Young children in the U.S. tend to hold narrow, idealized prototypes for animal and social categories, focusing on ideas about how categories should be and ignoring category variability. The current studies tested how children’s (N = 281) reliance on idealized prototypes might be shaped by adults’ communication of common essentialist and teleological biases. In Study 1, 7- to 8-year-old U.S. children viewed more average members of novel animal categories as prototypical when they heard a teacher correct a generic statement about a characteristic feature and highlight how varied features serve varied functions. In Study 2, explanations about varied functions alone explained this effect for novel animals, with mixed effects for familiar animals; there was no additive effect of correcting generic language. Children in Study 2 also expected functionally ideal features to be more frequent among category members, suggesting that idealized prototypes reflect mistaken assumptions that category members homogeneously share ideal features. Children in Study 2 did not explicitly disapprove of nonconformity, suggesting that idealized prototypes do not reflect an inability to dissociate how things are from how they should be. Together, these results support the proposal that U.S. children’s idealized prototypes are shaped by common conceptual biases perpetuated by cultural input.

Physiological and behavioral indicators of water buffaloes with access to heat mitigation resources in a grazing system during the hot season in the subtropics

Water buffaloes are increasingly being raised in similar way to dairy cows, in grazing systems frequently deprived of shade and water for immersion. This study aimed to evaluate the effects of different heat mitigation resources, 1) only shade and 2) shade plus water for immersion, on the behavioral repertoire and physiological characteristics of female grazing buffaloes in the subtropics during the hot season. Twenty buffaloes (Bubalus bubalis), including calves, heifers and non-lactating cows were allocated throughout the hot season (from December 2021 to April 2022) in a grazing system with two different heat mitigation resources (treatments): only shade (SH) and shade plus water for immersion (SHW). Diurnal behavioral repertoire was recorded every 15 days, individually and focally, at every 5 minutes for 12 hours per day. Heart rate (HR; beats/min), respiration rate (RR; breaths/min), rectal temperature (RT; °C) and panting score were also measured. Buffaloes reduced grazing time especially with THI above 75. Buffaloes at SHW spent more time grazing and lying than SH buffaloes (P < 0.05). Cows and heifers had higher ruminating (P < 0.05) and standing time (P < 0.05) compared with calves. Physiological variables did not differ (P > 0.05) between treatments (SH vs. SHW) and were positively correlated with air temperature and THI (P < 0.05). HR was higher for heifers (59.6) and calves (63.5) than for cows (53.3; P < 0.05). RT tended to be higher for heifers (38.4) and calves (38.3) than for cows (38.1; 0.05 < P < 0.10). However, respiration rate did not differ across buffalo categories (P > 0.05). Panting behavior was not reported throughout the observation days (panting score = 0). When both heat mitigation resources, shade and water for immersion were available, buffaloes preferred water for immersion to mitigate the effects of heat stress. Regardless animal category, buffaloes were able to maintain physiological variables within the normal range, indicating that providing shade and/or water for immersion, as environmental enrichment resources for thermoregulation, is suitable for heat stress mitigation in water buffaloes throughout the hot season in the subtropics.

Enteric Methane Production, Yield, and Intensity in Smallholder Dairy Farming Systems in Peri‐Urban Areas of Coastal West African Countries: Case Study of Benin

ABSTRACTEnteric methane (eCH4) is a major environmental pollutant emitted by ruminants. To target mitigation measures, it is necessary to accurately estimate GHG emissions from livestock farming. Until now, milk‐producing farms in the peri‐urban areas of South Benin are pasture‐based systems, and have been largely neglected by international research. Therefore, this study estimates eCH4 emissions from pasture‐based peri‐urban dairy farms across four different animal categories during dry and wet seasons. Six herds were selected for field measurements; one representative animal was selected per category from each herd and its body weight estimated. Subsequently, the selected animals were closely monitored on pasture for three consecutive days. Direct observation of their behavior and the hand‐plucking method were used to mimic the animals' selective foraging and to sample parts of the different plant species consumed in proportion to their, to determine the quality of their daily diet. The nutrient content and digestibility of the collected feed samples were assessed using near‐infrared spectroscopy. Additionally, 30 herds were monitored bi‐monthly during a 12‐month period to collect all input and output data, including milk yields. Annual enteric methane (eCH4) emissions per animal category were estimated using the IPCC Tier 2 method. Subsequently, the eCH4 intensities of lactating cows were calculated per kg of fat‐protein corrected milk (FPCM). All statistical analyses were performed using R software. Overall, the average annual eCH4 production was 40.6 kg/head/year and the eCH4 yield was 20.3 g/kg of dry matter intake, with significant differences between seasons and no differences between animal categories. Regardless of season, older animals yielded higher eCH4 outputs. The average eCH4 production per kg of live weight was 0.48 g for both seasons. The overall eCH4 intensity (g CH4/kg FPCM) recorded during the wet season (74.3) was higher than that recorded during the dry season (70.5).

Safety and efficacy of a feed additive consisting of l-arginine produced with Escherichia coliCGMCC 7.401 for all animal species (Eppen Europe SAS).

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the feed additive consisting of l-arginine produced by fermentation with a genetically modified strain of Escherichia coli (CGMCC 7.401). The additive is intended to be used in feed and water for drinking for all animal species and categories. The genetic modifications introduced do not raise safety concerns. No viable cells or DNA of the production strain were detected in the final product. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additive does not pose any safety concern with regard to the production strain. l-Arginine produced with E. coli CGMCC 7.401 is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the target species. The FEEDAP Panel has concerns on the use of amino acids in water for drinking for hygienic reasons, and due to the risk of imbalances when administered simultaneously via feed and water. The use of l-arginine produced with E. coli CGMCC 7.401 in animal nutrition is considered safe for the consumers and for the environment. The endotoxin activity of the additive does not represent a hazard for persons handling the additive. In the absence of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and/or eyes, or to be a dermal or respiratory sensitiser. The additive l-arginine produced with E. coli CGMCC 7.401 is regarded as an efficacious source of the essential amino acid l-arginine for non-ruminant species. For supplemental l-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen.

Determinants of Rabies Post-Exposure Prophylaxis Completion in Sarawak

Objective: Rabies remains persistent in Sarawak despite efforts to control its spread. This study investigates the determinants of rabies post-exposure prophylaxis (PEP) completion among individuals in Sarawak that have been exposed to potential rabies transmission through animal bites.Material and Methods: A retrospective cohort study, using a universal sampling approach was employed, utilizing data from the Sarawak i-Bite System. Binary logistic regression was used to identify significant variables: a p-value&lt;0.05 was considered as statistically significant.Results: The mean age of people having experienced animal bites was 38.1 (S.D.=22.4) years. Most were male (51.6%) and of Chinese ethnicity (37.2%). The predominant sites of animal bites were the upper (53%) and lower limbs (39.5%). Category 3 bite injuries and bites from fully confined pets were the most frequently reported (68.9% and 43.9%, respectively). In total 56.5% of the study population had a complete rabies vaccine regimen as post-exposure prophylaxis, while 5.4% had incomplete vaccinations, and 38% received no vaccination. The majority received treatment at government hospitals (59.1%). The significant determinants of rabies post-exposure prophylaxis completion in Sarawak were the Iban ethnicity (odd ratio (OR)=2.9, 95% confidence interval (CI):1.08-2.44, p-value=0.02), grade 3 bite (OR=3.9, 95% CI=,1.86-4.68, p-value&lt;0.001), pet mixed with stray (OR=2.41, 95% CI=1.32-2.33, p-value&lt;0.001), stray animals (OR=2.41, 95% CI=1.78-3.25, p-value,0.001) and treated in a government hospital (OR=0.63, 95% CI=0.47-0.83, p-value&lt;0.001).Conclusion: This study reported that only 56.5% of patients completed the rabies PEP series. The important determinants of PEP completion status were found to be the Iban ethnicity, bite severity, category of animal, and place of treatment. These findings offer valuable insights to assist the Sarawak State Health Department in prioritizing strategies to enhance the compliance rate, with the ultimate goal of eliminating dog-mediated Rabies deaths by 2030.

The Overall Situation of the Livestock and Evaluation of the Quantity of Beef Production in Batna City (Algeria)

Background: This study aims to determine the evolution of beef production during the last five years (2019-2023) in Batna city (Algeria) Methods: For the realization of this work we carried out an investigation at the municipal slaughterhouse of the city. During this investigation, we also took slaughter data. These include the weight of the carcasses and the classification of the slaughterhouse according to the categories of animals slaughtered. Moreover, a study was conducted to gather data from the Directorate of Agricultural Services (DSA) and the Ministry of Agriculture and Rural Development (MADR) regarding the number of cow herds in the studied city. The goal of this strategy is to comprehend the general state of the city’s livestock, including those destined for fattening and slaughter. Result: The animals intended for slaughter are mainly male cattle; of the young bulls and calves, the females admitted are cull dairy cows ( greater than 8 years). The results of this investigation showed that the beef production has experienced a remarkable drop from 1262560 kg in 2019 to 473430 kg in 2022, a slight change observed in 2023 but which still remains weak.

Prepartum anti-inflammatory therapies in Holstein dairy cows blocked by parity and body condition score group: Effects on metabolic stress, systemic inflammation, performance, and health

The objective of this study was to assess the effects of prepartum administration of anti-inflammatory therapies on body condition score (BCS), β-hydroxybutyrate (BHB) concentration, haptoglobin (HP) concentration, milk yield, milk components, rumination time, clinical health events and reproductive performance in Holstein dairy cows. At 14 d before the expected calving date, cows (PAR; n = 170) and heifers (nulliparous [NUL]; n = 63) were blocked by BCS group (optimal = 3-3.5 [OPT]; over-conditioned cows [OVERC; BCS ≥ 3.75 pts.]) and parity (NUL; PAR) and randomly allocated to one of 3 treatment groups: 1) ASA (n = 78): receive one oral administration of acetylsalicylic acid (4 boluses; 480 grain/bolus); 2) MEL (n = 76): receive one oral administration with meloxicam (1mg/kg of BW), or 3) PLC (n = 77): receive one oral treatment with gelatin capsules filled with water. Body condition score was assessed, and blood samples were collected, weekly starting one week before treatment until 3 weeks after calving. Daily milk yields and daily rumination times were collected from on-farm computer records. Dairy Herd Improvement Association (DHIA) monthly test data were collected to assess milk yield, somatic cell counts, and milk components. Furthermore, health events, culling rate, and reproductive performance data were collected from on-farm computer records. The data were analyzed using MIXED, GLIMMIX, and LIFETEST procedures of SAS as a randomized complete block design. On average, MEL-NUL cows produced 4.77 ± 0.93 kg/d and 4.81 ± 0.92 kg/d more milk from wk 6 to wk 21 of lactation compared with ASA-NUL and PLC-NUL cows, respectively. Similarly, there was a week by treatment by body condition group interaction (P = 0.01), where OVERC cows treated with MEL produced more milk from wk 10 to wk 15 of lactation compared with ASA- OVERC and PLC-OVERC cows. Parous cows treated with ASA had lower BCS compared with PAR cows treated with MEL or PLC. A lower percentage of OVERC cows treated with ASA became sick in the first 60 DIM compared with MEL- OVERC and PLC- OVERC cows (ASA = 23.88 ± 7.26%, MEL = 46.36 ± 8.57%; PLC = 46.74 ± 8.53%; P = 0.04). Parous cows treated with ASA had (P = 0.03) a higher hazard ratio to become pregnant by 300 DIM compared with PAR MEL cows. Although the study was not sized for finding treatment differences in blocking criteria groups, these results suggest that treatment with prepartum anti-inflammatory therapies may have positive effects on milk yield and postpartum health in specific groups of cows, such as NUL and OVERC cows, while it may not be recommended for other animal categories, such as parous cows and cows with optimal BCS. Larger studies are needed to strengthen the associations observed in this study.

Environmental factors and management practices associated with beef cattle carcass quality in the mid-west of Brazil.

The "Precoce MS" program, established by the Brazilian government in Mato Grosso do Sul in 2017, aims to encourage beef producers to harvest animals at younger ages to enhance carcass quality. About 40% of the beef produced in the state now comes from this program, which offers tax refunds ranging from 49% to 67% based on carcass classification and production system. Despite the program success, with participants delivering younger animals (with a maximum of 4 incisors), there remains significant variability in carcass quality. This paper investigates management practices and environmental factors affecting farm performance regarding carcass quality. Data from all animals harvested between the beginning of 2017 and the end of 2018 were analyzed, totaling 1,107 million animals from 1,470 farms. Farm performance was assessed based on the percentage of animals achieving grades "AAA" and "AA." Each batch of harvested cattle from each farm was categorized into two groups: high farm performance (HFP, with more than 50% of animals classified as "AAA" or "AA") and low farm performance (LFP, with less than 50% classified as such). A predictive logistic model was developed to forecast farm performance (FP) using 14 continuous and 15 discrete pre-selected variables. The most effective model, obtained through backward stepwise variable selection, had an R 2 of 0.18, accuracy of 71.5%, and AUC of 0.715. Key predictors included animal category, production system type, carcass weight, individual identification, traceability system, presence of a feed plant, location, and the Normalized Difference Vegetation Index (NDVI) from the 12-mo average before harvest. Developing predictive models of carcass quality by integrating data from commercial farms with other sources of information (animal, production system, and environment) can improve our understanding of production systems, optimize resource allocation, and advance sustainable animal production. Additionally, they offer valuable insights for designing and implementing better sectorial, social, and environmental policies by public administrations, not only in Brazil but also in other tropical and subtropical regions worldwide.

Patient-friendly clinics: exotics

Patient-centric care is increasingly better represented across many veterinary practices, particularly in the most commonly kept domestic companion pets. With specialised accreditations such as the International Society of Feline Medicine ‘Cat Friendly Clinic’ award, the Rabbit Welfare Association and Fund ‘Rabbit Friendly Vets’ initiative and the Dogs Trust ‘Dog Friendly Vet Clinics’, veterinary practices and individuals are able to demonstrate their commitment to species-focused practice, incorporating up-to-date techniques and implementing species-specific adaptations to ultimately reduce stress to the patients and owners while simultaneously cementing a pledge to advocate for these patients when they are under veterinary care. Currently, there are fewer available resources or accreditations for the less commonly presented pets, which are often grouped as ‘exotics’ – a large category of animals from a variety of taxonomic groups including avian, reptilian, amphibian, invertebrate, rodent and small mammal species – though this does not mean that they should not be represented or advocated for, in the same way.

Application of modern spatio-temporal analysis technologies to identify and visualize patterns of rabies emergence among different animal species in Kazakhstan.

During the period 2013-2023, 917 cases of rabies among animals were registered in the Republic of Kazakhstan. Out of these, the number of cases in farm animals amounted to 515, in wild animals to 50 and in pets to 352. Data on rabies cases were obtained from the Committee for Veterinary Control and Supervision of Kazakhstan, as well as during expeditionary trips. This research was carried out to demonstrate the use of modern information and communication technologies, geospatial analysis technologies in particular, to identify and visualize spatio-temporal patterns of rabies emergence among different animal species in Kazakhstan. We also aimed to predict an expected number of cases next year based on time series analysis. Applying the 'space-time cube' technique to a time series representingcases from the three categories of animals at the district-level demonstrated a decreasing trend of incidence in most of the country over the study period. We estimated the expected number of rabies cases for 2024 using a random forest model based on the space-time cube in Arc-GIS. This type of model imposes only a few assumptions on the data and is useful when dealing with time series including complicated trends. The forecast showed that in most districts of Kazakhstan, a total of no more than one case of rabies should beexpected, with the exception of certain areas in the North and the East of the country, where the number of cases could reach three. The results of this research may be useful to the veterinary service in mapping the current epidemiological situation and in planning targeted vaccination campaigns among different categories of animals.

Fostering creativity in science education reshapes semantic memory

Fostering creativity is vital for tackling 21st-century challenges, and education plays a key role in nurturing this skill. According to the associative theory, creativity involves connecting distant concepts in semantic memory. Here, we explore how semantic memory changes following an educational intervention intended to promote creativity. Specifically, we examine how a scientific education curriculum—Scientific Creativity in Practice (SCIP) program—impacts the semantic memory networks of 10–18-year-old students in a chemistry class (n = 176). Students in an Intervention group who received the SCIP intervention, and a Control group who did not, completed creative thinking tests, as well as verbal fluency tasks to estimate semantic networks in science-specific (chemistry) and domain-general (animal) categories. Results showed that the SCIP intervention enhanced performance on one test of scientific creative thinking but showed no significant difference on another. Using network science methods, we observed increased interconnectedness in both science-specific and domain-general categories, with lower path distances between concepts and reduced modularity. These traits define a ‘small-world’ network, balancing connections between closely related and remote concepts. Notably, the chemistry semantic network showed substantially more reorganization, consistent with the chemistry contents of the SCIP intervention. The findings suggest that semantic memory reorganization may be a cognitive mechanism underlying successful creativity interventions in science education.

Reference limits for blood gas analysis performed from coccygeal vessels of multiparous Holstein dairy cows: Effects of stage of lactation and season of sampling

Blood gas analysis is a great support to the diagnostic process of critically ill patients. Its correct application to the medicine of dairy cows depends on the availability of specific reference intervals that are still difficult to find in the literature. They may vary according to the type of blood sampled, animals' age and production stage, and climatic conditions. This study aimed at calculating the reference limits for some blood gas parameters in the blood collected from the coccygeal vessels of multiparous Holstein dairy cows. This site of sampling implies the risk of withdrawing blood of unknown origin (venous, arterial, or mixed), but has a high practical interest for the easy and quick performance and the minimal animal restraint required. Data from 379 cows were used, and reference limits were produced for pH, partial pressure of carbon dioxide (pCO2), bicarbonate concentration (HCO3), total carbon dioxide concentration (tCO2), oxygen saturation (sO2), hemoglobin (Hb), hematocrit (Hct), base excess (BE), glucose, Na, K, and ionized calcium (iCa). The effects of stage of lactation (5 to 60 vs. > 60 DIM) and season of sampling (cold vs. hot) were investigated, and specific reference limits were produced for each variable and each level of the factors whenever a significant effect was detected. The pH, sO2, K, and iCa were not influenced by season or stage of lactation. All the other blood gas parameters were significantly affected by season of sampling, and Hb, Hct, glucose, and Na were also affected by stage of lactation. Reference limits provided in this study are specific to the site of sampling (coccygeal vessels) and the animal category considered. Further studies are needed to produce reference intervals for other blood gas parameters, cow categories, and blood types.

An integral assessment of the impact of diet and manure management on whole-farm greenhouse gas and nitrogen emissions in dairy cattle production systems using process-based models

Feed management decisions are crucial in mitigating greenhouse gas (GHG) and nitrogen (N) emissions from ruminant farming systems. However, assessing the downstream impact of diet on emissions in dairy production systems is complex, due to the multifunctional relationships between a variety of distinct but interconnected sources such as animals, housing, manure storage, and soil. Therefore, there is a need for an integral assessment of the direct and indirect GHG and N emissions that considers the underlying processes of carbon (C), N and their drivers within the system. Here we show the relevance of using a cascade of process-based (PB) models, such as Dutch Tier 3 and (Manure)-DNDC (Denitrification-Decomposition) models, for capturing the downstream influence of diet on whole-farm emissions in two contrasting case study dairy farms: a confinement system in Germany and a pasture-based system in New Zealand. Considerable variation was found in emissions on a per hectare and per head basis, and across different farm components and categories of animals. Moreover, the confinement system had a farm C emission of 1.01 kg CO2-eq kg−1 fat and protein corrected milk (FPCM), and a farm N emission of 0.0300 kg N kg−1 FPCM. In contrast, the pasture-based system had a lower farm C and N emission averaging 0.82 kg CO2-eq kg−1 FPCM and 0.006 kg N kg−1 FPCM, respectively over the 4-year period. The results demonstrate how inputs and outputs could be made compatible and exchangeable across the PB models for quantifying dietary effects on whole-farm GHG and N emissions.

Neural Representations of Sensory Uncertainty and Confidence Are Associated with Perceptual Curiosity.

Humans are immensely curious and motivated to reduce uncertainty, but little is known about the neural mechanisms that generate curiosity. Curiosity is inversely associated with confidence, suggesting that it is triggered by states of low confidence (subjective uncertainty), but the neural mechanisms of this link, have been little investigated. Inspired by studies of sensory uncertainty, we hypothesized that visual areas provide multivariate representations of uncertainty, which are read out by higher-order structures to generate signals of confidence and, ultimately, curiosity. We scanned participants (17 female, 15 male) using fMRI while they performed a new task in which they rated their confidence in identifying distorted images of animals and objects and their curiosity to see the clear image. We measured the activity evoked by each image in the occipitotemporal cortex (OTC) and devised a new metric of "OTC Certainty" indicating the strength of evidence this activity conveys about the animal versus object categories. We show that, perceptual curiosity peaked at low confidence and OTC Certainty negatively correlated with curiosity, establishing a link between curiosity and a multivariate representation of sensory uncertainty. Moreover, univariate (average) activity in two frontal areas-vmPFC and ACC-correlated positively with confidence and negatively with curiosity, and the vmPFC mediated the relationship between OTC Certainty and curiosity. The results reveal novel mechanisms through which uncertainty about an event generates curiosity about that event.

Association Between Subclinical Thyroid Dysfunction and Cognitive Decline: Findings From the ELSA-Brasil Study.

Thyroid dysfunction has been associated with cognitive decline and dementia. However, the role of subtle thyroid hormone alterations in cognitive function is still debatable. Participants without overt thyroid dysfunction aged 35-74 years at baseline were evaluated in 3 study waves (2008-2010, 2012-2014, and 2017-2019). We assessed baseline thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3). Cognitive performance was evaluated every 4 years in each wave using 10-word immediate and late recall, word recognition, semantic (animals category) and phonemic (letter f) verbal fluency, and the trail-making B-version tests. A global composite z-score was derived from these tests. The associations of TSH, FT4, and FT3 levels with cognitive decline over time were evaluated using linear mixed-effect models adjusted for sociodemographic, clinical, and lifestyle variables. In 9524 participants (mean age 51.2 ± 8.9 years old, 51% women, 52% White), there was no association between baseline TSH, FT4, and FT3 levels and cognitive decline during the follow-up. However, increase in FT4 levels over time was associated with faster memory (β = -0.004, 95% CI = -0.007; -0.001, p = .014), verbal fluency (β = -0.003, 95% CI = -0.007; -0.0005, p = .021), executive function (β = -0.004, 95% CI = -0.011; -0.003, p < .001), and global cognition decline (β = -0.003, 95% CI = -0.006; -0.001, p = .001). Decrease in FT4 levels over time was associated with faster verbal fluency (β = -0.003, 95% CI = -0.007; -0.0004, p = .025) and executive function (β = -0.004, 95% CI = -0.007; -0.0003, p = .031) decline. An increase or decrease in FT4 levels over time was associated with faster cognitive decline in middle-aged and older adults without overt thyroid dysfunction during 8 years of follow-up.

The Effect of Russia's Invasion of Ukraine on Non-Human Animals: International Humanitarian Law Perspectives

AbstractSince Russia's full-scale aggression against Ukraine, there have been thousands of instances of civilian casualties, damage to the natural environment and cultural property, destruction of buildings and infrastructure, blockading of ports, siege, capturing installations containing dangerous forces, and other consequences that accompany hostilities. In addition to the fatalities related to humans (civilians and combatants alike) and their property or environment, the war in Ukraine has also accounted for non-human tolls – namely, the destruction of animals or damage to their habitats.The primary objective of this article is to study three patterns of animal suffering documented during Russia's invasion of Ukraine: (i) targeting zoos and killing zoo animals; (ii) extermination of the Black Sea dolphin population; and (iii) eating pigeons or other pets in besieged localities, and to analyse these patterns in the light of applicable rules of international humanitarian law (IHL).The idea of this research is to underline that war can have a significant effect on various categories of animals, and Russia's invasion of Ukraine is just another example of this. The article also discusses how, and the extent to which international law can provide protection for animals in armed conflict, and whether there are any gaps in the applicable IHL rules related to the protection of animals.