Angry Condition Research Articles

The impact of anger on intertemporal decision-making in individuals with internet addiction: an fNIRS study.

Intertemporal decision-making is the choice between an immediate smaller reward (SS) and a delayed larger reward (LL). Intertemporal decision-making depends on the interaction of the cognitive and emotional systems, and the latter is particularly vital. According to the Appraisal Tendency Frame (ATF) theory, anger influences intertemporal decision-making by increasing an individual's sense of certainty and control. This study examined whether anger affects intertemporal decision-making in individuals with internet addiction (IA) in this manner and investigated its neural mechanisms. Nineteen individuals with IA and 20 healthy controls were recruited. All subjects performed the Monetary choice task under anger and neutral emotions while functional near-infrared spectroscopy (fNIRS) equipment simultaneously recorded the hemodynamics in the prefrontal cortex (PFC). Individuals with IA showed a more considerable delay discount and lower brain activations in the orbitofrontal cortex (OFC) and left dorsolateral prefrontal cortex (L-dlPFC) compared to HC. Moreover, individuals with IA made more LL choices in the angry condition than in the neutral emotion, yet there was no difference in HC. The brain activation in L-dlPFC of individuals with IA tends to increase in the angry condition compared to the neutral condition. These findings revealed that impairment of intertemporal decision-making in individuals with individuals with IA might be related to the dysfunction of OFC and L-dlPFC. Our work also provided initial footing for the applicability of the appraisal tendency frame theory to individuals with IA, and L-dlPFC might play a role in the effects of anger on intertemporal decision-making.

Village dogs match pet dogs in reading human facial expressions

Most studies on dogs’ cognitive skills in understanding human communication have been conducted on pet dogs, making them a role model for the species. However, pet dogs are just a minor and particular sample of the total dog world population, which would instead be better represented by free-ranging dogs. Since free-ranging dogs are still facing the selective forces of the domestication process, they indeed represent an important study subject to investigate the effect that such a process has had on dogs’ behavior and cognition. Despite only a few studies on free-ranging dogs (specifically village dogs) having been conducted so far, the results are intriguing. In fact, village dogs seem to place a high value on social contact with humans and understand some aspects of humans’ communication. In this study we aimed to investigate village dogs’ ability in understanding a subtle human communicative cue: human facial expressions, and compared them with pet dogs, who have already provided evidence of this social skill. We tested whether subjects were able to distinguish between neutral, happy, and angry human facial expressions in a test mimicking a potential real-life situation, where the experimenter repeatedly performed one facial expression while eating some food, and ultimately dropped it on the ground. We found evidence that village dogs, as well as pet dogs, could distinguish between subtle human communicative cues, since they performed a higher frequency of aversive gazes (looking away) in the angry condition than in the happy condition. However, we did not find other behavioral effects of the different conditions, likely due to the low intensity of the emotional expression performed. We suggest that village dogs’ ability in distinguishing between human facial expressions could provide them with an advantage in surviving in a human-dominated environment.

Context-specific effects of threatening faces on alerting, orienting, and executive control: A fNIRS study

Real-world threatening faces possess both useful and irrelevant attributes with respect to the current goal. How these attributes interact and affect attention, which comprises at least three processes hypothesized to engage the frontal lobes (alerting, orienting, and executive control), remains poorly understood. Here, the neurocognitive effects of threatening facial expressions on the three processes of attention were examined through the emotional Attention Network Test (ANT) and functional near-infrared spectroscopy (fNIRS). Forty-seven (20M, 27F) young adults performed a blocked version of the arrow flanker task with neutral and angry facial cues applied in three cue conditions (no, center, and spatial). Hemodynamic changes occurring in participants' frontal cortices during task performance were recorded by multichannel fNIRS. Behavioral results indicated that alerting, orienting, and executive control processes existed in both the neutral and angry conditions. However, depending on the context, angry facial cues affected these processes differently compared with neutral facial cues. Specifically, the angry face disrupted the classical decrease in reaction time from the no-cue to center-cue condition specifically during the congruent condition. Additionally, fNIRS results revealed significant frontal cortical activation during the incongruent vs. congruent task; neither cue nor emotion significantly affected frontal activation. Thus, the findings suggest that the angry face affects all three attentional processes while exerting context-specific effects on attention. They also imply that during the ANT, the frontal cortex is most involved in executive control. The present study offers essential insights into how various attributes of threatening faces interact and alter attention.

Implikasi Religiusitas Pementasan Tari Sanghyang Jaran di Desa Bungkulan pada Masa Pandemi Covid 19

During the COVID-19 pandemic, the performance of the Sanghyang Jaran Dance in Bungkulan Village was delayed several times. The delay in the performance of this sacred dance ultimately has implications for the religious values ??of the adherents. This paper aims to identify the religious implications of the postponement of the Sanghyang Jaran dance performance. Kontjaraningrat and Robertson Smith's religious theory was used to interpret the data obtained. The results of the study indicate that there are at least three forms of religiosity implications experienced by the community during the postponement. First, the dancers are often visited by the spirit of Sanghyang Jaran in an unusual or angry condition. In addition, the dancer's family also experienced unusual illness and frequent household problems. Second, farmers experience anxiety due to declining yields and thefts that have occurred several times. Third, people experience discomfort with the surrounding conditions such as tense, many people are sick, so many people die in a row in the near future or grubug.

Functional Connectivity Between Basal Forebrain and Superficial Amygdala Negatively Correlates with Social Fearfulness

Social anxiety is characterized by an intense fear of evaluation from others and/or withdrawal from social situations. Extreme social anxiety can lead to social anxiety disorder. There remains an urgent need to investigate the neural substrates of subclinical social anxiety for early diagnosis and intervention to reduce the risk to develop social anxiety disorder. Twenty-nine young adults were recruited (10 males/19 females; mean age (SD) = 20.34 (2.29)). Trait-like social anxiety was assessed by Liebowitz Social Anxiety Scale. Functional magnetic resonance imaging was used with an emotional face-matching paradigm to probe brain activation in response to emotional stimuli including angry, fearful, and happy faces, with shape-matching as a control condition. Behavioral results showed positive correlations between Liebowitz Social Anxiety Scale scores and the reaction time in both angry and fearful conditions. The activation of superficial amygdala and the deactivation of basal forebrain in response to angry condition showed positive correlations with the level of social anxiety. In addition, the resting-state functional connectivity between these two regions was negatively correlated with the level of social anxiety. These results may help to understand the individual difference and corresponding neural underpinnings of social anxiety in the subclinical population, and might provide some insight to develop strategies for early diagnosis and interventions of social anxiety to reduce the risk of deterioration from subclinical to clinical level of social anxiety.

Proactive and reactive response inhibition of individuals with high schizotypy viewing different facial expressions: An ERP study using an emotional stop-signal task

The present study aimed to examine whether impairments in reactive (outright stopping) and proactive (preparation for stopping) response inhibition are affected by negative emotions in individuals with high schizotypy, a subclinical group at risk for schizophrenia, as well as the neural mechanisms underlying these processes. Twenty-seven participants with high schizotypy and 28 matched low-schizotypy individuals completed an emotional stop-signal task in which they responded to facial emotions (neutral or angry) or inhibited their responses (when the frame of the picture turned red). Electroencephalogram (EEG) data were also recorded during the task. At the neural level, analysis of go trials revealed that viewing angry faces impaired proactive inhibition. In addition, the high-schizotypy group exhibited a greater P3 amplitude in go trials in the neutral condition than the low-schizotypy group; however, no group difference was found in the angry condition. For stop trials (reactive inhibition), a smaller P3 amplitude was found in the angry condition than in the neutral condition. Moreover, high-schizotypy individuals showed smaller P3 amplitudes than low-schizotypy individuals. The current findings suggest that, at the neural level, viewing negative emotions impaired both proactive and reactive response inhibition. Individuals with high schizotypy exhibited impairments in proactive response inhibition in the neutral condition but not in the angry condition; they exhibited impaired reactive response inhibition in both emotion conditions. The present findings deepen our understanding of emotional response inhibition in individuals on the schizophrenia spectrum.

Dysregulated affective arousal regulates reward-based decision making in patients with schizophrenia: an integrated study

Schizophrenia is a chronic and severe mental disorder. Dysregulated decision-making and affective processing have been implicated in patients with schizophrenia (SZ) and have significant impacts on their cognitive and social functions. However, little is known about how affective arousal influences reward-based decision-making in SZ. Taking advantage of a two-choice probabilistic gambling task and utilizing three facial expressions as affective primes (i.e., neutral, angry, and happy conditions) in each trial, we investigated how affective arousal influences reward-related choice based on behavioral, model fitting, and feedback-related negativity (FRN) data in 38 SZ and 26 healthy controls (CTRL). We also correlated our measurements with patients’ symptom severity. Compared with the CTRL group, SZ expressed blunted responses to angry facial primes. They had lower total game scores and displayed more maladaptive choice strategies (i.e., less win-stay and more lose-shift) and errors in monitoring rewards. Model fitting results revealed that the SZ group had a higher learning rate and lower choice consistency, especially in the happy condition. Brain activity data further indicated that SZ had smaller amplitudes of FRN than their controls in the angry and happy conditions. Importantly, the SZ group exhibited attenuated affective influence on decision-making, and their impairments in decision-making were only correlated with their clinical symptoms in the angry condition. Our findings imply the affective processing is dysregulated in SZ and it is selectively involved in the regulation of choice strategies, choice behaviors, and FRN in SZ, which lead to impairments in reward-related decision-making, especially in the angry condition.

Does gaze direction of fearful faces facilitate the processing of threat? An ERP study of spatial precuing effects.

Eye gaze is very important for attentional orienting in social life. By adopting the event-related potential (ERP) technique, we explored whether attentional orienting of eye gaze is modulated by emotional congruency between facial expressions and the targets in a spatial cuing task. Faces with different emotional expressions (fearful/angry/happy/neutral) directing their eye gaze to the left or right were used as cues, indicating the possible location of subsequent targets. Targets were line drawings of animals, which could be either threatening or neutral. Participants indicated by choice responses whether the animal would fit inside a shoebox in real life or not. Reaction times to targets were faster after valid compared with invalid cues, showing the typical eye gaze cuing effect. Analyses of the late positive potential (LPP) elicited by targets revealed a significant modulation of the gaze cuing effect by emotional congruency. Threatening targets elicited larger LPPs when validly cued by gaze in faces with negative (fearful and angry) expressions. Similarly, neutral targets showed larger LPPs when validly cued by faces with neutral expressions. Such effects were not present after happy face cues. Source localization in the LPP time window revealed that for threatening targets, the activity of right medial frontal gyrus could be related to a larger gaze-orienting effect for the fearful than the angry condition. Our findings provide electrophysiological evidence for the modulation of gaze cuing effects by emotional congruency.

Memory of my victory and your defeat: Contributions of reward- and memory-related regions to the encoding of winning events in competitions with others

Social interactions enhance human memories, but little is known about how the neural mechanisms underlying episodic memories are modulated by rewarding outcomes in social interactions. To investigate this, fMRI data were recorded while healthy young adults encoded unfamiliar faces in either a competition or a control task. In the competition task, participants encoded opponents' faces in the rock-paper-scissors game, where trial-by-trial outcomes of Win, Draw, and Lose for participants were shown by facial expressions of opponents (Angry, Neutral, and Happy). In the control task, participants encoded faces by assessing facial expressions. After encoding, participants recognized faces previously learned. Behavioral data showed that emotional valence for opponents' Angry faces as the Win outcome was rated positively in the competition task, whereas the rating for Angry faces was rated negatively in the control task, and that Angry faces were remembered more accurately than Neutral or Happy faces in both tasks. fMRI data showed that activation in the medial orbitofrontal cortex (mOFC) paralleled the pattern of valence ratings, with greater activation for the Win than Draw or Lose conditions of the competition task, and the Angry condition of the control task. Moreover, functional connectivity between the mOFC and hippocampus was increased in Win compared to Angry, and the mOFC-hippocampus functional connectivity predicted individual differences in subsequent memory performance only in Win of the competition task, but not in any other conditions of the two tasks. These results demonstrate that the memory enhancement by context-dependent social rewards involves interactions between reward- and memory-related regions.

Prosodic influence in face emotion perception: evidence from functional near-infrared spectroscopy

Emotion is communicated via the integration of concurrently presented information from multiple information channels, such as voice, face, gesture and touch. This study investigated the neural and perceptual correlates of emotion perception as influenced by facial and vocal information by measuring changes in oxygenated hemoglobin (HbO) using functional near-infrared spectroscopy (fNIRS) and acquiring psychometrics. HbO activity was recorded from 103 channels while participants (hbox {n} = 39, hbox {age} = 20.37 hbox {years}) were presented with vocalizations produced in either a happy, angry or neutral prosody. Voices were presented alone or paired with an emotional face and compared with a face-only condition. Behavioral results indicated that when voices were paired with faces, a bias in the direction of the emotion of the voice was present. Subjects’ responses also showed greater variance and longer reaction times when responding to the bimodal conditions when compared to the face-only condition. While both the happy and angry prosody conditions exhibited right lateralized increases in HbO compared to the neutral condition, these activations were segregated into posterior-anterior subdivisions by emotion. Specific emotional prosodies may therefore differentially influence emotion perception, with happy voices exhibiting posterior activity in receptive emotion areas and angry voices displaying activity in anterior expressive emotion areas.

How Do Amusement, Anger and Fear Influence Heart Rate and Heart Rate Variability?

Emotions involve subjective experiences, behavioral performances, and physiological responses. Research concerning autonomic states corresponding to different emotions has prevailed for several decades. The present study was designed to investigate how specific emotions influence cardiac activities that reflect autonomic responses. Affective videos selected from a standardized Chinese database were used to induce amused, fearful, angry, and neutral emotions, while electrocardiogram and self-rated emotional experiences were recorded. Heart rate was significantly lower in the amused condition than in the angry, fearful and neutral condition. There were no significant differences among the latter three conditions. The root mean square of successive differences, an index of heart rate variability (HRV), was significantly larger in the amused condition than in the fearful, neutral, and angry conditions. It was also significantly larger in the angry condition than in the fearful condition. There were no significant differences between the fearful and neutral, or angry and neutral conditions. These results revealed that: (1) amusement activates the parasympathetic nervous system, and (2) compared with fear, anger is more likely to be linked with parasympathetic activation. We suggest that HRV, rather than the valence dimension (i.e., positive or negative) be regarded as a potential index to discriminate emotions related to approach or avoidance motivation.

Are lecturers who show emotions perceived as understanding? How culture and teacher’s display of emotion are related to students’ judgments about a teacher’s personality

ABSTRACTUniversity lecturers tend to show emotions in congruence with the cultural-educational practices with which they are familiar. As lecturers’ display of emotion can affect students’ learning, it is important to understand how culture influences students’ perception and interpretation of their lecturers’ display of emotion. In this study, we examined how a university lecturer’s display of emotions while giving negative feedback to students on their achievement in different cultural-educational contexts affected students’ perception of the lecturer’s personality. In an online survey university students in Germany (N = 148) and Russia (N = 136) read vignettes in which lecturers gave negative feedback to students during consultation hours. The lecturer’s display of emotion varied (no emotion vs. pity vs. anger) in the vignettes. The participants judged the lecturer’s personality by rating 10 items regarding the lecturer’s conscientiousness, cautiousness, and understanding. Students in Germany differed significantly from students in Russia in their ratings of the lecturer’s conscientiousness and understanding and the students’ judgment of the lecturer’s personality varied significantly between the angry condition and neutral condition. Both groups of students considered the lecturer to be more conscientious, cautious, and understanding when he showed pity than when he showed no emotion or anger.

Processing differences between monolingual and bilingual young adults on an emotion n-back task

Bilingualism is associated with enhancement of executive control (EC) across the lifespan. Working memory and non-verbal emotion regulation both draw upon EC mechanisms so may also be affected by bilingualism, but these relationships are not fully understood. These relationships were explored using an n-back task with distracting emotional stimuli administered to young adults while continuous EEG was recorded. Monolinguals were faster but less accurate on the 2-back than bilinguals, and monolingual accuracy was more impeded by the presence of emotional stimuli than was that of bilinguals. The P300 event-related potential, a neural signature of working memory processing in the n-back, had smaller amplitudes in both groups on the 2-back than the 1-back, but attenuation in response to distracting emotional stimuli was greater for bilinguals than monolinguals. P300 latencies were also differentially affected by emotional stimuli in each group: Bilingual latencies were constant across emotions but monolingual latencies increased from neutral to angry conditions. In general, bilingual performance was less impacted by the emotional distraction than was that of the monolinguals. Additionally, bilinguals adjusted to the changing demands of the 1-back and 2-back conditions by recruiting neural networks to support different behavioral outcomes than monolinguals.

The Influence Of Self-generated Emotions On Aerobic Physical Performance

PURPOSE: The purpose of this study was to test the influence of self-generated emotions on exercise performance during an aerobic workout on a cycle ergometer. METHODS: Sixteen males (Mean ± STDEV age = 23.1 ± 2.7 years; height = 162.7 ± 26.2 cm; weight = 82.6 ± 16.1 kg) performed 4 sessions of aerobic exercise on a cycle ergometer. A randomized within-subjects experimental design was used to test the hypotheses. The four randomized testing sessions included: the control (No-Emotion), sadness (SAD), happiness (HAPPY), and anger (ANGRY). Cycle ergometer seat heights for subjects were measured and used for each session. Subjects performed a 3-min warm-up, a 15-min workout on the cycle ergometer at a 2.5 kg resistance, and a 3-min cool-down. Subjects were instructed to stop pedaling on the cycle after the warm-up and take 1-2 min to begin self-generating the emotion being tested. Subjects alerted testers when ready to begin workout. Flexibility was measured and recorded before and after testing. Heart rate (HR) was observed and recorded before testing, every 3 min during exercise, and immediately after exercise. Blood pressure (BP) measurements were taken before and immediately after each testing session, and at the 5 min, 10 min, and 15 min mark following cycling exercise. RESULTS: No significant condition main effect for systolic and diastolic BP was observed, but there was a significant time main effect (p < .05). HR values were significantly higher during the ANGRY session compared to the values recorded during the No-Emotion and SAD sessions (p < .05). Participants covered significantly longer distance during the ANGRY condition compared to all other conditions (p < .05). CONCLUSIONS: Self-generation of angry emotion during aerobic exercise resulted in significant increases in heart rate and distance traveled compared to all other emotions tested. Increased performance during the ANGRY session could be due to increased sympathetic nervous system activity and/or hormonal changes such as epinephrine, norepinephrine, and cortisol leading to a temporarily altered state of consciousness similar to a situation that is perceived as a threat or danger. Further studies should investigate the effects of emotion on hormonal changes, performance, and hemodynamic responses during long-distance events such as a 10K and marathon.

How disgust facilitates avoidance: an ERP study on attention modulation by threats.

This study investigated the attention modulation of disgust in comparison with anger in a dot-probe task. Results indicated a two-stage processing of attention modulation by threats. When participants viewed the cues that were represented by Chinese faces (i.e. the in-group condition), it was found at the early processing stage that an angry face elicited a larger occipital P1 component whereas a disgusted face elicited a smaller P1 for validly than for invalidly cued targets. However, the result pattern was reversed at the later processing stage: the P3 amplitudes were larger for valid disgust cues but were smaller for valid angry cues, when both were compared with invalid cue conditions. In addition, when participants viewed the cues that were represented by foreign faces (i.e. the out-group condition), the attention modulation of disgust/anger diminished at the early stage, whereas enhanced P3 amplitudes were observed in response to validly cued targets in both disgusting and angry conditions at the later stage. The current result implied that although people can perceptually differentiate the emotional categories of out-group faces as accurately as in-group faces, they may still be not able to psychologically understand the subtle differences behind different categories of out-group facial expressions.

Childhood and adult trauma both correlate with dorsal anterior cingulate activation to threat in combat veterans

Prior studies of adult post-traumatic stress disorder (PTSD) suggest abnormal functioning of prefrontal and limbic regions. Cumulative childhood and adult trauma exposures are major risk factors for developing adult PTSD, yet their contribution to neural dysfunction in PTSD remains poorly understood. This study aimed to examine the neural correlates of childhood and adult trauma exposure and post-traumatic stress symptoms (PTSS) within a single model. Method Medication-free male combat veterans (n=28, average age 26.6 years) with a wide range of PTSS were recruited from the community between 2010 and 2011. Subjects completed an emotional face-morphing task while undergoing functional magnetic resonance imaging (fMRI). Clinical ratings included the Clinician-Administered PTSD Scale (CAPS), Childhood Trauma Questionnaire (CTQ) and Combat Exposure Scale (CES). A priori regions were examined through multivariate voxelwise regression in SPM8, using depressive symptoms and IQ as covariates. In the angry condition, CAPS scores correlated positively with activation in the medial prefrontal cortex [mPFC; Brodmann area (BA) 10, z=3.51], hippocampus (z=3.47), insula (z=3.62) and, in earlier blocks, the amygdala. CES and CTQ correlated positively with activation in adjacent areas of the dorsal anterior cingulate cortex (dACC; BA 32, z=3.70 and BA 24, z=3.88 respectively). In the happy condition, CAPS, CTQ and CES were not correlated significantly with activation patterns. dACC activation observed in prior studies of PTSD may be attributable to the cumulative effects of childhood and adult trauma exposure. By contrast, insula, hippocampus and amygdala activation may be specific to PTSS. The specificity of these results to threat stimuli, but not to positive stimuli, is consistent with abnormalities in threat processing associated with PTSS.

Visual search for real emotional faces: the advantage of anger

Previous research indicates angry expressions are detected faster than happy ones, but most data concern schematic faces. The present study looks into the differences in visual search performance in a sample of adults confronted with real neutral, angry, and happy faces of 9 different individuals. Participants searched for a discrepant happy or angry face among neutral or emotional faces. We compared detection speed and accuracy between the angry and happy discrepant face conditions. We measured state and trait anxiety with the State and Trait Anxiety Inventory (Spielberger, 1983; Pitariu & Peleasa, 2007) and looked for anxiety modulation on search. Results suggested angry faces were detected more efficiently and no modulation by anxiety. This study offers preliminary evidence for a general attentional bias towards facial threat in a task created to resemble real-life situations of searching through a crowd.

Mad enough to see the other side: Anger and the search for disconfirming information

The current research explored the effect of anger on hypothesis confirmation—the propensity to seek information that confirms rather than disconfirms one's opinion. We argued that the moving against action tendency associated with anger leads angry individuals to seek out more disconfirming information than sad individuals, attenuating the confirmation bias. We tested this hypothesis in two studies of experimentally primed anger and sadness on the selective exposure to hypothesis confirming and disconfirming information. In Study 1, participants in the angry condition were more likely to choose disconfirming information than those in the sad or neutral condition when given the opportunity to read more about a social debate, and reading the disconfirming information affected their subsequent attitude. Study 2 measured participants' opinions and information selection about the 2008 US Presidential Election and their desire to “move against” a person or object. Participants in the angry condition reported a greater tendency to oppose a person or object, which resulted in the attenuation of the confirmation bias.

CORTICAL DYSFUNCTION IN ADOLESCENTS WITH SCHIZOPHRENIA DURING WORKING MEMORY COMPONENT PROCESSES - A FUNCTIONAL MAGNETIC RESONANCE IMAGING STUDY

Klinefelter (van Rijn et al., 2006a). Difficulties in social adaptation and abnormal brain asymmetries suggest that a genetic mechanism (involving genes on theX chromosome)might affect the development of social cognition in XXY men. Language and emotion are important aspects of social cognition. Reduced or abnormal lateralization of language has been found in Klinefelter's syndrome (Geschwind,1998; van Rijn et al., 2008). Additionally, impairments in emotional prosody perceptionhavebeen reported (vanRijn et al., 2007).Weexpected that lateralization of emotional prosody differed in Klinefelter's syndrome. Therefore, we used fMRI-guided transcranial magnetic stimulation (TMS) to study lateralization effects. Methods: Sevenmenwith Klinefelter's syndrome and seven controls (matched on age, gender and education) performed an emotional prosody task during fMRI-scanning. In this task, subjects attended to the affective (happy, sad, angry or anxious) intonation and had to ignore the neutral semantic content of the sentences. We used fMRIguided TMS (with BrainVoyager neuronavigation) to reduce excitability of areas thatwere active during emotional prosody processing in the MR scanner (left and right superior temporal gyrus). TMS was performed for 20 minutes on 1 Hz. After stimulation, the subjects performed the emotional prosody task again. In addition, a baseline measurement without TMS was included. Results were analyzed with repeated measures analysis of variance (ANOVA). Results: Klinefelter patients showed a trend to react slower than controls (p=0.12). They also showed longer reaction times on the angry condition after stimulation of the right superior gyrus (p=0.05), whereas controls reacted faster. No other effects of TMS reached significance. Discussion: Menwith Klinefelter's syndrome respondedmore slowly to sentences with an angry intonation in the emotional prosody task after right STG stimulation, whereas controls responded faster. The emotion angry is hypothesized to be primarily processed by the left hemisphere. Thus, the involvement of the right STG in anger prosody processing in Klinefelter patients suggests a switch in lateralization. The faster responses in the healthy group for this emotion might be due to callosal disinhibition of the left hemishere by the right hemisphere TMS. As fMRI studies have suggested similar patterns of aberrant lateralization in Klinefelter syndrome and schizophrenia, our results may have implications for understanding schizophrenia.

Neural basis of attributional style in schizophrenia

Attributional style means how people typically infer the causes of emotional behaviors. No study has shown neural basis of attributional style in schizophrenia, although it was suggested as a major area of social cognition research of schizophrenia. Fifteen patients with schizophrenia and 16 healthy controls underwent functional magnetic resonance imaging while performing three (happy, angry, and neutral) conditions of attribution task. Each condition included inferring situational causes of an avatar’ (virtual character) emotional or neutral behavior. In the between-groups contrast maps of the happy conditions, the patient group compared to the control group showed decreased activations in the inferior frontal (BA 44) and the ventral premotor cortex (BA 6), in which the % signal changes were associated with negative symptoms. In the angry conditions, the patient group compared to the control group exhibited increased activations in the precuneus/posterior cingulate cortex (Pcu/PCC) (BA 7/31), in which the % signal changes were related to positive symptoms. In conclusion, patients with schizophrenia may have functional deficits in mirror neuron system when attributing positive behaviors, which may be related to a lack of inner simulation and empathy and negative symptoms. In contrast, patients may have increased activation in the Pcu/PCC related to self-representations while attributing negative behaviors, which may be related to failures in self- and source-monitoring and positive symptoms.