Rock is a widely used engineering material, and accurate understanding of its internal microcrack evolution process during loading can provide a theoretical basis for preventing instability and failure in rock engineering. The rock pressure test system and acoustic emission equipment were used to carry out uniaxial loading and acoustic emission monitoring tests on fractured red sandstone. Based on the RA and AF values of acoustic emission and the fractal theory, the internal crack patterns and evolution rules of red sandstone with different crack angles were explored. The results show that the compressive strength of red sandstone varies with the crack Angle in the shape of “U”, and there is an obvious stress drop after the elastic stage of 30° and 45° crack red sandstone, which has a good correspondence with the acoustic emission ringing count rate. During the loading process, the damage mainly caused by tension cracks first appears inside the rock, and then the tension cracks increase steadily and the shear cracks gradually increase, indicating that the rock enters the stage of fracture instability development. With the development of shear cracks, the peak strength is finally reached and the instability failure occurs. During the loading process of 30° fracture red sandstone, the corresponding stress drop phenomenon of “shear crack group” appears. According to the D/S statistical analysis of different crack samples based on acoustic emission ringing count, the fractal dimension presents a decreasing-rising-decreasing trend with the increase of crack inclination, which corresponds to the change of the complexity of crack development in rock.