Aneurysm Of Interventricular Septum Research Articles

Abstract 4123899: Stroke Risk in Patients with an Isolated Interventricular Membranous Septal Aneurysm

Aim: This study investigates the prevalence of isolated interventricular membranous septal (IVMS) aneurysms detected via echocardiography and assesses the associated stroke risk without other classical risk factors. Methods: We searched the echocardiography database at Mount Sinai Morningside from January 2017 to September 2023. Identified echocardiograms were reviewed to confirm IVMS aneurysms and exclude sinus of Valsalva aneurysms. Patients with concurrent structural heart anomalies were excluded. Medical records were examined for baseline characteristics, risk factors, and cortical brain infarcts. Results: From 51,732 subjects, 18 were identified with IVMS aneurysms, yielding a prevalence of 0.04%. Four patients with significant structural heart disease were excluded, resulting in a final sample size of 14. Of these, 9 (64%) were female with a mean age of 59.6, and 5 (36%) were male with a mean age of 55.4. The mean BMI was 27.9 kg/m 2 , with 4 classified as obese. All patients were nonsmokers; 2 had a family history of stroke. One patient had diabetes, 8 had hyperlipidemia, and 9 had hypertension. Only one patient had paroxysmal atrial fibrillation, with a CHA2DS2-VASc score of 0. Echocardiography revealed structurally normal hearts with a mean left ventricular ejection fraction of 61% and a mean left atrial volume index of 24.8 mL/m 2 . The mean neck diameter of the aneurysm was 8.7 mm, and the mean diameter was 11.9 mm. Two patients had inter-atrial septal aneurysms, and one had a patent foramen ovale. Out of the 14 patients, 5 had a history of ischemic stroke (4) or transient ischemic attacks (1), all of whom were 64 years or younger with a mean RoPE Score of 6 and a mean CHA2DS2-VASc score of 1.6 at the time of their first neurologic event. All patients were treated with aspirin and statin therapy. Two patients had recurrent strokes, one of whom had four recurrent strokes, all cortical infarcts. These patients were switched to clopidogrel after 3 months of dual antiplatelet therapy. No anticoagulation was used. Conclusion: This retrospective study highlights a notable association between isolated IVMS aneurysms and an increased risk of ischemic stroke (36%) and recurrent ischemic stroke (14%). Despite their rarity, these anomalies should be considered in unexplained strokes. Optimal management strategies remain ambiguous, but anticoagulation may be favored based on presumed stroke mechanisms. Large-scale multicenter studies are needed for validation.

Neonatal interventricular septal aneurysm associated with right coronary artery fistula.

We present a neonatal case of interventricular septal aneurysm associated with right coronary artery fistula. This report is the first to document such a neonatal case, highlighting the importance of early diagnosis and surgical intervention.

Transcatheter Aortic Valve Implantation for Severe Aortic Stenosis and Large Membranous Interventricular Septal Aneurysm.

Transcatheter Aortic Valve Implantation for Severe Aortic Stenosis and Large Membranous Interventricular Septal Aneurysm.

Aneurysm of interventricular septum: what an anaesthesiologist must know

Aneurysm of interventricular septum (IVSA) is a rare congenital anomaly. It has been documented in isolation but is seen in association with congenital heart disease in 0.3% of cases and in association with ventricular septal defect in 19% of cases. Etiologies are considered to be idiopathic formation, trauma, infection or spontaneous closure of pre-existing ventricular septal defect. Clinical manifestations are variable, some patients are asymptomatic whereas others can present with hemodynamic compromise.
 Key words: Anesthesia; Cardiac aneurysm
 Citation: Kiran S, Bansal T, Jakhar P. Aneurysm of interventricular septum: what an anesthesiologist must know. Anaesth. pain intensive care 2021;25(6):832–833;
 DOI: 10.35975/apic.v25i6.1714

An interventricular membranous septal aneurysm obstructing the right ventricle outflow tract in a five-year-old boy: a case report

BackgroundWhile the aneurysms of the membranous septum (AVS) are rare, the possibility that they lead to obstruction is even rarer. To the best of our knowledge, 11 similar cases have been reported since 1982.Case presentationInitially, the five-year-old boy was evaluated for dyspnoea that had been present since birth. He did not receive any medical treatment until the previous year. At the age of four, the transthoracic echocardiography showed a large aneurysm extending to the right ventricular outflow tract (RVOT) and causing RVOT stenosis. Complete surgical resection of the aneurysmal tissue was performed, and the boy was discharged home in satisfactory condition.ConclusionsAs the occurrence of RVOT obstruction by a membranous ventricular septal aneurysm is very rare, we are reporting the second case in which an aneurysm of the membranous septum dynamically obstructed the RVOT in a child. We are also reviewing all the previously reported similar cases in the literature. Further studies are needed to obtain a more comprehensive understanding of aneurysms of the membranous septum (AVS).

Dynamic right ventricular outflow tract obstruction caused by alarge interventricular membranous septal aneurysm.

Dynamic right ventricular outflow tract obstruction caused by alarge interventricular membranous septal aneurysm.

Fetal Echocardiography in Uncommon Prenatal Cardiac Anomalies: Right Atrium Diverticulum, Interventricular Septal Aneurysm, Left and Right Ventricle Diverticulum – Report from Referral Center for Fetal Cardiology in Poland

Abstract The prenatal detection of congenital anomalies of heart walls is very rare. We present a unique series of 8 cases with prenatal echocardiographic monitoring, treatment and postnatal follow-up, providing new insight into this “mysterious” heart problem

Interventricular Membranous Septal Aneurysm Incidentally Diagnosed during Computed Tomographic Angiography in a Patient with Infrequent Supraventricular Tachycardia

Interventricular membranous septal (IVMS) aneurysm is a rare condition with no accurate incidence. It is known to be associated with 0.3 % of congenital heart disease and 19 % of ventricular septal defects. IVMS aneurysm is often asymptomatic but can be complicated with right ventricular obstruction, rupture, thromboembolism, and conduction defects. Clinicians and radiologist should be aware about this rare clinical entity and evaluation of any possible underlying cardiac abnormalities should be performed. Conservative management with close follow up is the mainstay of management in the absence of complication.

Intraoperative Echocardiographic Detection of Septal Aneurysm and Additional Ventricular Septal Defect in a Child with Tetralogy of Fallot

ABSTRACT A 2-year-old child was diagnosed with subaortic ventricular septal defect (VSD) with severe infundibular and valvular pulmonary stenosis (PS) by transthoracic echocardiography. Intraoperative transesophageal echocardiography (TEE) detected aneurysmal interventricular and interatrial septum (IAS), subaortic VSD, and right ventricular outflow tract (RVOT) with an additional midmuscular VSD. The aneurysmal interventricular septum (IVS) was repaired. An accessory tricuspid papillary muscle was attached to RVOT, which was augmented with a transannular pericardial patch to have minimal postoperative gradient without sacrificing the accessory papillary muscle (APM). This rare case poses a challenge to the anesthetist and surgeon in the form of diagnostic differences, severe right ventricle (RV) dysfunction with aneurysmal IVS, and difficulty in reconstruction of RVOT. Intraoperative TEE played a greater role to diagnose the IVS aneurysm, additional VSD and guide for appropriate surgery. How to cite this article Das S, Kumar A. Intraoperative Echocardiographic Detection of Septal Aneurysm and Additional Ventricular Septal Defect in a Child with Tetralogy of Fallot. J Perioper Echocardiogr 2017;5(1):21-24.

Perioperative Transesophageal Echocardiographic Diagnosis of Membranous Interventricular Septal Aneurysm in Two Patients

ABSTRACT Aneurysms of interventricular septum are a rare anomaly usually seen as an incidental finding on echocardiography. Rarely, they can cause right ventricular outflow tract obstruction. They can present in patients having other cardiac lesions. Diagnosis of interventricular septal aneurysm is not straightforward. They can be confused with sinus of valsalva aneurysm or ventricular septal defect on transthoracic echocardiography. Transesophageal echocardiography (TEE) provides a better alternative to delineate the interventricular septal aneurysm. We describe the TEE diagnosis of membranous interventricular septal aneurysm in two dissimilar patients who presented for cardiac surgery at our cardiac center. How to cite this article Dutta V, Negi SL, Puri GD, Singh RS. Perioperative Transesophageal Echocardiographic Diagnosis of Membranous Interventricular Septal Aneurysm in Two Patients. J Perioper Echocardiogr 2016;4(1):14-16.

Interventricular septum aneurysm: Two differently managed cases and association with bicuspid aortic valve

Interventricular septum aneurysm: Two differently managed cases and association with bicuspid aortic valve

PP-143 An Incidentally Detected Giant Membranous Interventricular Septal Aneurysm Secondary to Previous Surgery for Subaortic Valvular Stenosis

PP-143 An Incidentally Detected Giant Membranous Interventricular Septal Aneurysm Secondary to Previous Surgery for Subaortic Valvular Stenosis

Septic Pulmonary Emboli and Right Ventricular Obstruction in a Membranous Interventricular Septal Aneurysm

Although the majority of patients with perimembranous ventricular septal defect and septal aneurysm remained asymptomatic, some of them presented with serious complications during adulthood and thus required high risky surgery. In accordance with other rare condition, the incidence and natural history have not been well documented. This case describes the occurrence of a septic pulmonary emboli associated with right ventricular outflow tract obstruction in a young child.

Massive Interventricular Septal Aneurysm and Stroke in a Healthy Young Patient: Guilt by Association?

Aneurysm of the membranous interventricular septum is an uncommon cardiac defect that is, on rare occasions, associated with embolic stroke. We describe here the case of an otherwise healthy, 41-year-old man who presented to the hospital with acute-onset confusion and left-sided body weakness attributed to a right middle cerebral artery ischemic stroke. He experienced a nearly complete resolution of deficits following systemic thrombolytic therapy. After an extensive workup, the presumed mechanism of stroke was a thromboembolus that originated in a massive aneurysm of the patient's membranous interventricular septum. Due to a perceived risk of surgical morbidity, the patient was managed conservatively with anticoagulation. He denied further events and reported nearly full function at follow-up.

Large interventricular septal aneurysm with thrombo-embolism in a healthy woman

A 59-year-old Hispanic woman with no significant medical history presented with a stroke while travelling on a South East Asian cruise. Work up included an echocardiogram showing a large multilobulated aneurysm (arrow) with a base measuring 2.2 cm (green line) with several smaller lobulations in the parasternal long-axis view ( Panel A …

Live Three-Dimensional Transesophageal Echocardiography in an Unusual Case of Aorto-Left Ventricular Tunnel with a Large Interventricular Septal Aneurysm

Aorto-left ventricular tunnel (ALVT) is a rare congenital malformation. We report an unusual case of ALVT with a large interventricular septal aneurysm causing severe aortic regurgitation and left ventricular outflow obstruction diagnosed with real time three-dimensional transesophageal echocardiography (3D TEE). Real time 3D TEE allows for assessment and novel views of complex cardiac abnormalities and can aid in perioperative monitoring.

A case of double-chambered right ventricle associated with an interventricular septal aneurysm in an elderly patient.

Double-chambered right ventricle is a congential malformation caused by an anomalous muscle band obstructing the right ventricular outflow tract. Most reported cases of this condition have been diagnosed in infants, or adolescents. We encountered a 61-year-old woman with a double-chambered right ventricle, associated with a large interventricular septal aneurysm, which is a rare complication. The right ventricular obstruction was corrected with surgery.

Ischemic neurologic event in a child as a result of ventricular septal aneurysm

Aneurysm of the interventricular septum without a shunt was found by means of transthoracic echocardiography in a 6-year-old boy with acute hemiparesis. Until the time of the incident, he had been healthy. The aneurysmal sac contained 2 clots, presumably resulting in the ischemic cerebral infarct. On the basis of the echocardiographic scan, successful surgery was performed. To the best of our knowledge, this is the first report describing such dramatic sequelae of interventricular septal aneurysm.

Echocardiographic findings in left ventricular septal aneurysm

The unusual echocardiographic findings are described in a case of congenital interventricular septal aneurysm. The aneurysm involved the middle part of the interventricular septum and was associated with a cleft of the mitral valve and an atrial septal defect but with no evidence of an atrioventricular septal defect. There was extensive fibroelastosis of the right ventricle. The patient presented with brief runs of ventricular tachycardia.

Aneurysm of interventricular septum with aortic valve malformation in an infant.

Aneurysm of interventricular septum with aortic valve malformation in an infant.