Occurrence Of Anemia Research Articles

Adolescent nutrition program that is integrated and gender responsive through nutritional actions in the context of support government realize gold generation

Children's health age schools and teenagers moment was determine the degrees generation nation in the future. We need prepare them to become a source power of quality human beings, such as through education health in order to increase their capability to avoid theirselves from possible problems​ impact. Indonesian teenagers experience three burden nutrition which classified as short (25%), thin (8%), overweight body weight (15%) or obesity and about 10% of male teenagers and 23% of female teenagers were suffering from anemia. Teenager is half from source Power man for the future and a huge asset For growth economic and social especially teenager daughter who prone to suffer from anemia due to lost blood at the moment menstruation. Female teenagers who suffer from anemia are at risk experienced anemia at the time pregnant and will impact negative to growth and development fetus in content as well as potential give rise to complications pregnancy and childbirth, even cause death to mother and child. Anemia in children ages 5-14 years amounting to 26.8% and aged 15-24 years by 32%. Activity implementation action program dedicated to implement some programs, such as hemoglobin examination in students, strengthen supplementation of iron substance, and acid folate weekly or Fe table for female teenager, education multi-sectoral nutrition, and sharing and drinking with added tablets blood. Activity This need done monitoring and evaluation the extent of the effectiveness of this program in frame prevent occurrence of anemia in adolescents.

A study to assess the occurrence of anaemia and beta-thalassemia in the tribal population residing in the Yadadri-Bhuvanagiri district of Telangana state

ABSTRACT Background: This study aimed to estimate the prevalence of anaemia and haemoglobinopathies, particularly beta-thalassemia in the tribal population of the Yadadri-Bhuvanagiri district of Telangana. Methods: The sample consisted of a tribal population (Banjara) that visited voluntary blood camps set up in tribal settlements, local schools, and the Gram-panchayat office, in collaboration with local healthcare workers. Haemoglobin measurements (Anaemia) and Mentzer index of whole blood (EDTA) samples were used as diagnostic screening tools for categorising the population at risk of beta-thalassemia. HPLC was used as a confirmatory test. Results: The study included a total of n = 479 (68% females and 32% males) voluntary adult participants of Banjara. Based on the haemoglobin levels, 105 females (32%) were found to be anaemic as compared to 24 males (15.5%). Among the female population, a small percentage of individuals had severe anaemia (1.9%), while most had mild (80%) or moderate anaemia (18%); on the other hand, males primarily had moderate anaemia. Out of the total screened population, 6.7% (5.2% with low Hb levels (anaemic), 3.3% by MI) were found to be thalassemia based on anaemia and Mentzer index as a screening tool. Conclusion: The prevalence of beta-thalassemia was found 6.7% in the Banjara population.

A Multicenter Retrospective Cohort Study Assessing the Incidence of Anemia in Patients Associated With Uterine Fibroids.

Uterine fibroids are benign tumors that develop from the smooth muscle tissue of the uterus, typically during a woman's reproductive years. A substantial proportionof women with uterine fibroids exhibit symptoms, including menorrhagiathat considerably compromise theirquality of life. This study aims to characterizethe fibroid subtype most commonly associated with the incidence ofanemia. This retrospective multi-center cohort study investigated the incidence of anemia in premenopausal women who were diagnosed with uterine fibroids between January 2016 and December 2022. Fibroid position, size, location, and number were assessed by trans-abdominal/vaginal ultrasound and hysteroscopy and correlated to the pre-treatment hemoglobin level. Three-quarters of patients (n=6) with submucosal fibroid presented with any form of anemia followed by 59.3% (n=115) of patients with intramural fibroid and only 36.8% (n=25) of patients with sub serousal fibroid. Interestingly, there was no difference between the groups with regard to the severity of anemia at presentation. Most red blood cells (RBCs) and hemoglobin (Hb) indices were comparable between the groups, except for mean corpuscle volume (MCV) as it was significantly lower in patients with intramural fibroids. Moreover, our investigations showed that the submucosal fibroids tend to present in a higher number as well as the biggest in size. The multivariable logistic regression showed that subserosal fibroids are associated with the lowest risk of developing anemia. In conclusion, our results suggest that the occurrence of anemia should always be considered in women with submucosal fibroids. However, after adjusting for other contributing factors such as menorrhagia, submucosal fibroid did not show an increase in the risk of anemia.

ANALISIS FAKTOR YANG MEMENGARUHI KEJADIAN ANEMIA IBU HAMIL DI WILAYAH KERJA PUSKESMAS BIROMARU

Anemia is a common problem frequently experienced by pregnant women, where the hemoglobin levels in the blood fall below normal. This condition is often caused by an iron deficiency. This research aims to identify the factors influencing the occurrence of anemia in pregnant women in the work area of Biromaru Health Center, Sigi Regency, Central Sulawesi Province. The research method employed is quantitative with a cross-sectional analytical approach, aiming to observe the relationship between various variables without intervention. The sample consisted of 76 pregnant women. The results indicate a significant relationship between knowledge, attitude, adherence to iron tablet consumption, and nutritional status and the occurrence of anemia in pregnant women in the area. Pregnant women's knowledge about anemia significantly afFects the incidence of anemia. Positive attitudes towards health and adherence to iron tablet consumption also have a significant impact on preventing anemia in pregnant women. In conclusion, the importance of knowledge, positive attitudes towards health, adherence to iron tablet consumption, and attention to nutritional status in preventing anemia in pregnant women is highlighted. Efforts to improve knowledge and awareness among pregnant women, as well as appropriate iron supplementation, can be efFective steps in addressing the issue of anemia in pregnant women in the area.

META ANALYSIS: EFFECT OF FOOD DIVERSITY, TEA OR COFFEE CONSUMPTION ON ANEMIA IN ADOLESCENT GIRLS

Background: The prevalence of anemia in adolescent girls in the world is 29.60%, and in Indonesia is 32%. A number of primary studies reveal various determinants that contribute to the occurrence of anemia in adolescent girls. Purpose: To analyze the results of primary studies related to consumption patterns (food diversity and tea/coffee consumption) and the occurrence of anemia in adolescent girls. Methods: The research design was a systematic review with meta-analysis. Journal sources from three databases (Google Scholar, Pubmed, and Scopus) using Publish or Perish software with keywords using boolean operators and featured with PRISMA. Inclusion criteria were full text from 2013 to 2022, articles in Indonesian or English language, cross-sectional studies, and the population was adolescent girls, using multiple logistic regression analysis with adjusted odds ratio. The study obtained nine articles from 11,421 articles identified. Data analysis using Rev.Man 5.4. Results: The prevalence of anemia in adolescent girls was 30.83% (95% CI: 15.71-45.95). Food diversity (SMD=1.87; 95% CI=0.88-3.97; P-value=0.10) and tea or coffee consumption (SMD=2.46; 95% CI=1.15-5.27; P-value=0.02) influence the incidence of anemia in adolescent girls. Conclusion: Low food diversity and tea or coffee consumption increase the risk of anemia in adolescent girls. Implementing balanced nutritional guidelines to prevent anemia is recommended.

Inflammatory indexes and anemia in chronic kidney disease: correlation and survival analysis of the National Health and Nutrition Examination Survey 2005–2018

Background There is currently no research on the correlation between novel inflammatory indexes systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and the risk of anemia in chronic kidney disease (CKD) population, as well as survival analysis in CKD with anemia. Methods This investigation encompassed 4444 adult subjects out of the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2018. The study utilized multi-variable logistic regression to assess the relationship between SII, NLR, PLR, and anemia risk occurrence in CKD population. Survival differences in CKD patients with anemia, based on varying levels of SII, NLR, and PLR were evaluated employing Kaplan–Meier and Cox proportional hazards models. Results The adjusted logistic regression model demonstrates that SII, NLR, and PLR are associated with the risk of anemia occurrence in CKD population. Kaplan–Meier’s analysis reveals significant differences in survival rates among CKD patients with anemia stratified by NLR levels. The adjusted Cox proportional hazards model shows that the higher NLR group has a 30% elevated risk of all-cause mortality contrasted with lower group (hazard ratio, HR: 1.30, confidence interval (CI) [1.01, 1.66], p value <.04). Restricted cubic spline (RCS) demonstrates no nonlinear relationship between NLR and all-cause mortality. Lastly, sub-cohort analysis indicates that in populations with diabetes, hypertension, and hyperuricemia, NLR levels have a greater impact on all-cause mortality. Conclusions Controlling inflammation may reduce the occurrence of anemia in CKD populations, with NLR serving to be a potential prognostic indicator for survival results within CKD patients suffering from co-morbid anemia.

Gambaran Kepatuhan Ibu Hamil dalam Mengonsumsi Tablet Fe Terhadap Kejadian Anemia di Wilayah Kerja Puskesmas Sadananya

Anemia is a concerning condition for pregnant women. The World Health Organization (WHO) reports that the prevalence of anemia among pregnant women is around 35-37%, and this increases with the progression of pregnancy. Nutritional iron deficiency anemia tends to be more prevalent in developing countries than in developed ones. The incidence rate of anemia in Ciamis Regency, based on the health profile of the regency, is 20.05%. This study aims to depict the compliance of pregnant mothers in consuming iron (Fe) tablets concerning the occurrence of anemia in the working area of Sadananya Community Health Center in 2020. The research design employed in this study is descriptive research. The population consists of all pregnant mothers with anemia during pregnancy in the working area of Sadananya Community Health Center, Ciamis Regency, amounting to 723 individuals in the year 2020. Cluster Sampling technique was used for sample selection. The analysis conducted in this study is univariate. The research results revealed that almost all respondents, totaling 67 individuals (84.4%), were non-compliant in consuming Fe tablets, whereas a small portion of respondents, totaling 12 individuals (15.2%), exhibited compliance in consuming Fe tablets. In conclusion, the majority of respondents, 67 individuals (84.8%), were non-compliant in consuming Fe tablets. It is recommended that relevant institutions, particularly Sadananya Community Health Center, become more proactive in providing education to pregnant women about pregnancy-related anemia and the importance of consuming Fe tablets.

Child health outcomes and associated factors among under five years children in Ethiopia: a population attributable fractions analysis of Ethiopia demographic and health survey (2005–2016)

IntroductionIn Ethiopia, more than half (57%) of children aged 6–59 months were estimated to be anemic in 2016 alone. The country had about 37% of under-five children suffering from stunting and under-five mortality rate of 59 deaths per 1000 live births in 2019. The main purpose of this paper was to estimate the proportion of under-five children prevented from childhood undernutrition, anemia, and under-five mortality by removing the risk factors or inequalities.MethodThis cross-sectional study was based on a pooled total sample of 29,831 children aged 0–59 months drawn from three rounds of the Ethiopian Demography and Health Surveys (2005–2016). We employed multiple logistic regression analysis to identify the modifiable risk factors associated with childhood anemia, undernutrition, and under-five mortality among under-five children. We also used Population Attributable Fractions (PAFs) to estimate the proportion of under-five children that could be prevented from childhood undernutrition, anemia, and under-five mortality by removing inequalities.ResultPAF analyses of risk factors of childhood anemia confirmed that 38.5% of occurrence of childhood anemia was attributed to five selected risk factors, which include having a large household size (5+), being in a poor household, being born from anemic and unemployed mothers, and being breastfed for less than six months. About 45.6% of occurrences of childhood undernutrition were attributed to unimproved toilet facility, solid cooking fuel, and home delivery. About 72% of the reported under-five mortality could possibly be averted by removing the use of unimproved toilet facilities, early age childbirth (< 18 years old mothers), and a large number of children ever born to mothers and less than six months breastfeeding practice at the population level.ConclusionThe present study suggests that a substantial reduction in the prevalence of childhood anemia, undernutrition, and under-five mortality in the country is attainable if child survival-focused program interventions and policies target households and mothers with low socioeconomic status and those who have low awareness of child healthcare, including breastfeeding practice and use of safe sanitation facilities.

The Risk Factors for Anemia in Women at Third Trimester of Pregnancy in the Primary Health Center of Tanjung Sekayam: A Case-Control Study

Background: The presence of anemia in pregnant women significantly affects the health of both mothers and their fetuses. Around 37% of pregnant women worldwide experience anemia. In the Community Health Center of Tanjung Sekayam, the prevalence of anemia in women at the third trimester of their pregnancy was notably high, at 50.4%. Objectives: This study aims to identify the risk factors for anemia in women at third trimester of pregnancy in the working area of the Community Health Center of Tanjung Sekayam Subdistrict, Sanggau Regency. Methods: This study was an observational research with a case-control design. The study population consisted of 153 women at third trimester of pregnancy, receiving antenatal care in the Community Health Center of Tanjung Sekayam. The samples included 62 respondents, selected through a simple random sampling, comprising of 31 cases and 31 controls. Data were collected using questionnaires and analyzed with the Chi-Square test to assess the factors associated with the occurrence of anemia. Results: There was a relation among maternal age (p=0.000; OR=22.9), interpregnancy interval (p=0.024; OR=6.9), parity (p=0.011; OR=2.2), nutritional status (chronic energy deficiency) (p=0.000; OR=11.3), compliance (p=0.021; OR=3.9), and knowledge (p=0.001; OR=8.2) and the prevalence of anemia in the third trimester. However, the family support did not show any significant relation. Conclusions: Maternal age, pregnancy interval, parity, nutritional status, compliance with iron tablet intake, and knowledge are related to the prevalence of anemia in third trimester of pregnancy. Family support did not show any significant relation with the incidence of anemia, possibly due to the limitations in measuring the family support itself and other factors, such as discomfort in consuming iron tablets and forgetfulness. More structured interventions and intensive education on the importance of iron and nutrition during the pregnancy are needed to reduce the risk of anemia.

Anemia incidence and influencing factors among children aged 0-6 years in Shannan city, Xizang Autonomous Region

Objective: To investigate the prevalence and influencing factors of anemia children aged 0-6 years in Shannan city, Xizang Autonomous Region. Methods: A cross-sectional study was performed to measure hemoglobin of 12 405 children aged 0-6 years in 12 counties (districts) of Shannan city, Xizang Autonomous Region and basic information including gender, age, ethnicity, address, local altitude, urban area, agricultural and pastoral areas, etc were collected. According to the altitude of the surveyed children's place of residence, anemia in children under the plain standard and the prevalence of anemia after adjusting for altitude were reported, and the influencing factors of anemia in these children were analyzed by Logistic regression methods. Results: Among the 12 405 children, 6 383 (51.46%) were males, 6 022 (48.54%) were females, 462 (3.72%) were newborns, 68 (0.55%) were 1 month old children, 153 (1.23%) were 4-<6 months old children, and 11 722 (94.49%) were 6 months to 6 years old children. The prevalence of anemia in children aged 0-6 years in Shannan city before altitude correction was 15.50%(1 923/12 405), and it was 57.84% (7 175/12 405) after altitude correction. The hemoglobin level in the children was (131±20) g/L. Univariate analysis showed that the anemia rate of males was higher than that of females (59.17% (3 777/6 383) vs.56.43% (3 398/6 022), P<0.05), the anemia rate of Tibetan children was higher than that of children of other ethnic groups (58.21% (6 992/12 011) vs.46.45% (183/394), P<0.05), the anemia rate of children in agricultural and pastoral areas was higher than that of urban children (58.75% (6 212/10 574) vs.(52.59% 963/1 831), P<0.05), and the anemia rate of children in higher-altitude areas was higher than that of children in high-altitude areas (67.98% (2 773/4 079) vs.52.87% (4 402/8 326), P<0.05). Logistic regression analysis revealed that girls (OR=0.89, 95%CI 0.83-0.96), children of other ethnic groups (OR=0.72, 95%CI 0.58-0.89), children aged 4-<6 months (OR=0.40, 95%CI 0.24-0.67) and children aged 6 months to 6 years (OR=0.59, 95%CI 0.43-0.82) were protective factors, and children who lived in agricultural and pastoral areas (OR=1.15, 95%CI 1.04-1.28) and children living at altitudes higher than 4 000 m areas (OR=1.88, 95%CI 1.73-2.04) were independent risk factors for the occurrence of anemia. Conclusions: The prevalence of anemia in children aged 0-6 years in Shannan city was still relatively high. It might be affected by factors such as sex, ethnicity, age of the children, place of residence and altitude where the children lived.

Iron Metabolism in Pediatric Living related Liver Transplantation

Abstract Introduction Iron deficiency is a frequent cause of anemia in liver transplant recipients, especially children. Rejection and infection are incriminated causes for occurrence of anemia after liver transplantation (LR). Aim of the Work We aimed to assess iron homeostasis in children who have undergone living related LT (LRLT) and its correlation with occurrence of rejection and infection. Patients and Methods The study was conducted on 35 children who have undergone LRLT. The patient characteristics, frequency of infection and rejection episodes, laboratory investigations including complete blood picture (CBC) and Iron profile (total iron binding capacity (TIBC),serum iron and ferritin) during the patient follow up visits were reported. Results Males were 68.58% of the studied patients and females were 31.42%. Their ages ranged from 1.3-15 years at time of LT with mean (SD) of 7.18 (3.8)years. The mean (SD) duration since LT was 4.83 (4.2) years. The commonest indication to LT was highgamma-glutamyl transferase (GGT) cholestasis (34.7%) followed by biliary atresia (21.7 %). Thirteen percent of patients had low hemoglobin (Hb) of whom 4.3% had normocytic normochromic anemia and 8.7% had microcytic hypochromic anemia. Serum iron was normal in 79.6% of patients and low in 20.4%, and ferritin was normal in 58.7% of patients and low in 41.3% while TIBC was normal in 82.6% of patients and low in 17.4%. Only serum iron showed significant negative correlation with white blood cells (WBCs) (P &amp;lt; 0.05). The iron parameters levels were not different in patients with no rejection or only one attack of rejection and the patients with multiple rejection episodes (P &amp;gt; 0.05). Conclusion Anemia is a reported complication after pediatric LT. Further studies are needed to assess the long term effect of post-LT anemia on patient outcome after LT.

564 The Assessment and Management of Anaemia in Patients Who Underwent an Emergency Laparotomy

Abstract Aim Emergency Laparotomies (EmLap) carry a significant risk of morbidity and mortality. Peri and post-operative anaemia are associated with higher complication rates, delayed healing, and lethargy. This study aimed to assess the occurrence of anaemia in EmLap patients upon admission and discharge, as well as to evaluate its management. Method Data was collected from 260 participants undergoing EmLap from 2016 to 2019 that completed a follow up questionnaire in 2020, as part of PEEL 2 (Patients Experience of Emergency Laparotomy) in Cardiff, a retrospective cohort study. 34% of patients (n=90) had a Haemoglobin (Hb) level on admission and discharge and were included into the study. Information on transfusions and prescriptions of ferrous fumarate tablets during admission and on discharge were obtained from electronic records. Results 46.7% (n=42) were anaemic at time of admission and further 19 patients were anaemic after surgery. 61 patients (68%) were discharged with anaemia post EmLap. Of the 61 patients discharged with anaemia only 10 (16%) were given treatment; 7 (11%) were offered a blood transfusion, 2 (3%) were prescribed ferrous fumarate tablets and 1 (1.6%) received a combination of both. Discharge summaries did not highlight the issue and follow up advice was not given to GPs. Conclusions 2/3 of EmLap patients were discharged with anaemia and was not addressed. A greater understanding is needed to appreciate the impact of anaemia on EmLap patients’ such as fatigue levels. It can be avoided if a closer look at patients’ blood results is conducted and treated aligning with the NICE guidelines.

Risk Factors For Anemia In Pregnant Women In The Third Trimester

Anemia is a condition in which the percentage of erythrocytes and hemoglobin (Hb) levels of pregnant women fall below normal. Ponorogo Regency Health Profile Data in 2022, there were 1,746 anemic pregnant women out of 10,878 (16.50%). This study aims to provide an overview of risk variables and initiatives aiming to decrease the proportion of anemia cases among pregnant women. Method: Analytical observational research was used to conduct the study, which was conducted retrospectively from quantitative data. All 62 pregnant women with anemia in the third trimester formed the study sample for the case population. Two independent (free) factors were used in this study: parity, education, nutritional status, maternal age, and gestational age. The prevalence of anemia in third trimester pregnant women is the dependent variable. The instrument used by researchers is an observation sheet. Data analysis to test the truth of the hypothesis uses Regression Logistic Analysis. Result: The findings of the study revealed that maternal age (p-value 0.009) and gestational age (p-value 0.027) were risk factors that had an impact on the incidence of anemia at the North Ponorogo Health Center, indicating that gestational age affects the incidence of anemia. Maternal age has a significant risk impact on the occurrence of anemia. The data showed that the incidence of anemia with a risk of 0.884 times was not affected by nutritional status (p-value = 0.727), parity (p-value = 0.043), education (p-value = 0.043), while the incidence of anemia with a risk of 8.483 times was influenced by parity. Discussion: The findings of this study lead to the conclusion that influencing risk factors were gestational age, maternal age and parity, while nutritional status and education were risk factors that had no effect on anemia in pregnant women. Suggestion: It is expected to provide advice or reference to health centers in order to conduct early detection or further improve comprehensive examinations in order to reduce the prevalence of anemia in the third trimester of pregnancy among several parameters that have been examined by researchers.

Hubungan Pengetahuan Dan Sikap Ibu Dengan Pemberian Makanan Pendamping Asi (MP -ASI ) Pada Anak Usia 6 - 24 Bulan Di PBM Susi Rini Safitri Kab.Simalungun Tahun 2023

Infancy between the ages of 6-24 months is a golden age for child growth and development. This period is a good opportunity for parents to strive for optimal child growth and development. One effort that parents can make to achieve this is through good and correct parenting patterns given to children. This study aims to determine the Relationship between Mother's Knowledge and Attitudes with the Provision of Complementary Foods (MP-ASI) to Children Aged 6-24 Months at PBM Susi Rini Safitri, Simalungun Regency in 2023. This type of research is an analytical survey study with a cross-sectional method approach. The population is all mothers who have children aged 6-24 months as many as 42 people. The number of samples used was 42 people obtained using the Total sampling technique. The data analysis technique used chi square. the results obtained in this study are from 42 respondents, there is a relationship between maternal attitudes and the Provision of Complementary Food for Breast Milk (MP-ASI) in Children Aged 6-24 Months shows that the p value = 0.000 &lt;0.05. there is a relationship between maternal knowledge and the Provision of Complementary Food for Breast Milk (MP-ASI) in Children Aged 6-24 Months shows that the p value = 0.012 &lt;0.05. It is recommended for Health Workers to increase counseling related to the Occurrence of Anemia in Pregnant Women.

Supplementary decompression and extended surgical time contribute to hidden blood loss In percutaneous endoscopic lumbar discectomy

BackgroundIt is widely believed that the Percutaneous endoscopic lumbar discectomy (PELD) is associated with minimal blood loss. However, significant perioperative hidden blood loss (HBL) is frequently unaccounted for. This study aimed to investigate HBL and peri-operative factors contributing to HBL in a series of individuals undergoing PELD. Methodology: A total of 156 consecutive patients with a mean age of 43.6 years (ranging from 18 to 80 years) who underwent PELD at our department from May 2019 to November 2020, were included in the study. Factors including gender, age, body mass index, symptom duration, operation approach/technique, operation duration, the presence of associated chronic diseases, and improvements in the Visual Analog Scale (VAS) score, Japanese Orthopaedic Association (JOA) score and the Oswestry Disability Index (ODI) were analyzed, and Gross's formula was applied to calculate blood loss, which was used to determine HBL. ResultsThe average total blood loss (TBL) was 221.0 ± 126.2 mL, while the average HBL was 181.7 ± 119.0 mL (82.2 % of TBL). There was no statistically significant difference in HBL between the transverse surgical approach and the interlayer approach. Additionally, no significant differences were observed in improvements in VAS, JOA, and ODI scores between the two surgical approaches. However, the multivariate linear regression analysis revealed that longer surgical time and foraminal decompression were factors contributing to the increase in HBL, which subsequently led to the occurrence of post-operative anemia. ConclusionHBL is significant in PELD cases with long surgical time and lumbar foraminal decompression.

Analysis of Factors in Reducing the Incidence of Anemia in Adolescent Girls at Ummi Kulsum Banjaran SMP Bandung District

Adolescence is a transition period from childhood to adulthood. In Indonesia, around 90% of women menstruate every month, but the onset of menstruation can cause anemia for teenagers who experience it. This is caused by several things, of course because there is irregular bleeding, this is caused by the teenager’s age itself. , parental factors, including education and work, each person’s food intake/nutritional status, and also the menstrual cycle/length of menstruation experienced each month. This research aims to determine the factors associated with the occurrence of anemia in adolescent girls at Umi Kulsum Banjaran Middle School in 2022. The research method used is a quantitative analytical approach research design with a cross sectional research design. The research population was all 120 female students and the sample used was 55 people using the random sampling technique. Data collection was carried out by means of interviews and direct examination of respondents. Data analysis went through three stages, univariate (frequency distribution), bivariate (chi square) and multivariate analysis (Logistic Regression). The results of the research show that there are factors that are associated with the incidence of anemia in adolescent girls, including age, nutritional status and length of menstruation with a p-value &lt;0.05. It is recommended that students increase their knowledge about reproductive health, especially those related to enstruation, educational institutions can optimize education about adolescent reproductive health by collaborating with health workers in the surrounding environment.

Hubungan Pola Makan, Gaya Hidup, Dan Dukungan Keluarga Terhadap Kejadian Anemia Pada Remaja Putri Di Madrasah Tsanawiah Tanwirian Cianjur

Introduction: Anemia is a nutritional problem that is widely found throughout the world which does not only occur in developing countries but also in developed countries. Young women have a ten times greater risk of suffering from anemia compared to young men. This is because young women experience menstruation every month and are in a period of growth, so they need more iron intake. The impact of the incidence of anemia in adolescents can reduce concentration and academic achievement, as well as affect productivity among adolescents. The general objective of this study was to determine the relationship between diet, lifestyle, and family support for the incidence of anemia in young women at Madrasah Tsanawiah Tanwiriah Cianjur in 2023. Methods: This study used a quantitative method with a cross-sectional study design. The total population is 176 with a sample of 64 young women. Results: The results of the univariate statistical test showed that 36 (56,3%) female students had a poor lifestyle; 50 (78,1%) had a poor diet; and 38 (59.4%) had a supportive family. The results of the bivariate analysis found that the p-values ​​of all p-value variables &lt;α (0,05); diet (0,016); lifestyle (0,011); and family support (0,002) mean that Ho is rejected or there is a significant relationship between pattern eating, lifestyle, and family support on the incidence of anemia in young women. Discussion: This study concludes that diet, lifestyle, and family support have a significant effect on the occurrence of anemia in adolescents, the p-value of diet 0,016 evidences this; lifestyle 0,011; and family support 0,002. Suggestions from the research that has been done, the researcher tries to provide some suggestions to future researchers. With the hope that the suggestions given can be useful in further research.

THE THE ROLE OF NUTRITIONAL STATUS ON HEMOGLOBIN LEVELS IN ADOLESCENTS

Background: Adolescents were one of the strong foundations for the future of the nation because of their role in development and progress of the country. Healthy physical and psychological conditions will form a strong and resilient adolescent character which is affected by adequate nutritional intake. So that if nutrients are not sufficient, it can cause disturbances in metabolic processes. Inadequate intake of nutrients such as protein and iron will aggravate the occurrence of anemia and lead to malnutrition. Indirectly, nutritional status will also affect the occurrence of anemia. Objectives: This study was to examine the relationship between nutritional status and adolescent hemoglobin levels. Methods: This study was an analytic study with Cross Sectional approach. Respondents were 46 students of SMP PGRI 01 Bantur in Malang regency conducted in August 2023. Independent variable was nutritional status using weight, height and Body mass index (BMI) and dependent variable was anemia using hemoglobin level. BMI was calculated using formula weight divided by height square. The analysis used both univariate and bivariate analysis. Bivariate analyzed using Spearman rank correlation test. Results: Results showed 76,1% adolescents classified normal nutritional, 19,6% overweight and 2,2% underweight and obese. The hemoglobin level, 86,9% normal and 13,1% anemia. Based on the results of statistical tests using rank spearman test, the p value = 0.044 less than 0,05. It means there was a significant correlation between nutritional status and anemia. Conclusion: There is a relationship between nutritional status with Hb levels in adolescents. Enrichment of nutritional intake will give big impact on nutritional and anemia status among adolescents.

Clinical outcomes and resource utilization in patients with multiple myeloma admitted with gastrointestinal bleeding.

e19522 Background: In multiple myeloma (MM) patients, GIB can be due to factors such as abnormal proteins affecting the GI tract, coagulation issues, or secondary conditions like amyloidosis. There's limited scientific evidence examining outcomes among patients presenting with both GIB and MM. Thus, our objective was to assess clinical outcomes in this specific population. Methods: We accessed the National Inpatient Sample from 2017-2020 to identify adult patients with MM hospitalized due to GIB. The primary endpoint was inpatient mortality, with secondary endpoints including length of stay and total hospital charges. We utilized multivariable logistic regression analysis to estimate clinical outcomes, considering a significance threshold of P &lt; 0.05. Results: We identified 4,067,364 hospitalizations with GIB, among which 22,000 (5.9%) presented with MM. Comparing MM and Non-MM cohorts, the mean age was 71.9 vs 67.8 years, males constituted 58% vs 52.2%, and White ethnicity accounted for 55.6% vs 66.1%. The prevalence of obesity was 10.6% vs 14.5%, diabetes mellitus was 32.1% vs 33.8%, chronic obstructive pulmonary disease was 16.9% vs 20.4%, dyslipidemia was 38.5% vs 40.7%, atrial fibrillation was 27.7% vs 25.6%, hypertension was 22.9% vs 34.7%, heart failure (HF) was 30.7% vs 26.4%, peripheral vascular disease (PVD) was 2.9% vs 4.1%, acute kidney injury was 45.6% vs 29.4%, anemia was 26.3% vs 27.7% and chronic kidney disease (CKD) was 51.9% vs 28.6%. Clinical outcomes revealed stark differences between MM and Non-MM cohorts: in-hospital mortality rates were 10.9% vs 6.3% with an odds ratio (OR) of 1.5 (CI 1.4-1.7); LOS was 9.6 days vs 6.7 days (IRR 1.26, CI 1.21-1.32); and hospital charges were $30,006 vs $20,172 (IRR 1.34, CI 1.26-1.42). All data demonstrated a p-value &lt; 0.001 and were adjusted for various factors including age, sex, race, comorbidity indices, obesity, atrial fibrillation, diabetes mellitus, hypertension, peripheral vascular disease, acute kidney injury, chronic kidney disease, nicotine and alcohol use, stroke, acute respiratory failure, and inflation during 2017-2020. Conclusions: Patients hospitalized for GIB and MM were comparatively older, with a larger male population and fewer Caucasians. They exhibited higher Afib, HF, AKI, and CKD rates with lower occurrences of obesity, DM, COPD, dyslipidemia, HTN, anemia and PVD. This group showed a significantly worse mortality rate with prolonged hospital stays and resource utilization. This entails to have prompt medical attention, appropriate management of bleeding, and addressing the underlying causes are crucial in improving outcomes and reducing mortality rates. Treatment strategies often involve a multidisciplinary approach involving oncologists, hematologists, gastroenterologists, and other specialists to provide comprehensive care tailored to the individual's condition.

The risk profiles of pregnancy-related cerebral venous thrombosis: a retrospective study in a comprehensive hospital

ObjectivesTo investigate the risk factors and underlying causes of pregnancy-related cerebral venous thrombosis (PCVT).MethodsA retrospective cohort of 16 patients diagnosed with CVT during pregnancy and postpartum (within six weeks after delivery) in a comprehensive hospital in China between 2009 and 2022 were carefully reviewed, focusing on demographic, clinical, and etiological characteristics, especially underlying causes. We matched 16 PCVT patients with 64 pregnant and puerperal women without PCVT to explore risk factors and clinical susceptibility to PCVT.ResultsPCVT occurred commonly during the first trimester (43.75%) and the puerperium (37.5%). The frequency of anemia, thrombocytosis and thrombocytopenia during pregnancy, dehydration, and pre-pregnancy anemia was significantly higher in women with PCVT than in those without PCVT (P < 0.05). Among the 16 patients, five were diagnosed with antiphospholipid syndrome and one was diagnosed with systemic lupus erythematosus. Three patients had distinct protein S deficiency and one had protein C deficiency. Whole Exome Sequencing (WES) was performed for five patients and revealed likely pathogenic mutations associated with CVT, including heterozygous PROC c.1218G > A (p. Met406Ile), heterozygous PROS1 c.301C > T (p. Arg101Cys), composite heterozygous mutation in the F8 gene (c.144-1259C > T; c.6724G > A (p. Val2242Met)) and homozygous MTHFR c.677C > T (p. Ala222Val).ConclusionsThe occurrence of anemia, thrombocytopenia and thrombocytosis during pregnancy, dehydration and pre-pregnancy anemia suggested a greater susceptibility to PCVT. For confirmed PCVT patients, autoimmune diseases, hereditary thrombophilia, and hematological disorders were common causes. Screening for potential etiologies should be paid more attention, as it has implications for treatment and long-term management.